Mannose-binding lectin and its associated proteases (MASPs) mediate coagulation and its deficiency is a risk factor in developing complications from infection, including disseminated intravascular coagulation

Immunobiology

Volumn 216, Issue 1-2, 2011, Pages 96-102

  Takahashi, Kazue ^a,d   Chang, Wei Chuan ^a   Takahashi, Minoru ^b   Pavlov, Vasile ^c   Ishida, Yumi ^b   La Bonte, Laura ^c   Shi, Lei ^a   Fujita, Teizo ^b   Stahl, Gregory L ^c   Van Cott, Elizabeth M ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b FUKUSHIMA MEDICAL UNIVERSITY   (Japan)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

^d Harvard Medical School ^*  (United States)

Author keywords

Coagulation; Deficiency; Infection; Inflammation; Mannose binding lectin; MASP

Indexed keywords

INTERLEUKIN 6; MANNAN BINDING LECTIN; MANNAN BINDING LECTIN ASSOCIATED SERINE PROTEINASE; MANNAN BINDING LECTIN ASSOCIATED SERINE PROTEINASE 1; MANNAN BINDING LECTIN ASSOCIATED SERINE PROTEINASE 3; THROMBIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD CLOTTING; CONTROLLED STUDY; DISSEMINATED INTRAVASCULAR CLOTTING; ENZYME ACTIVITY; ENZYME DEFICIENCY; HEMOSTASIS; INFECTION COMPLICATION; INFLAMMATION; LIVER INJURY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN DEPLETION; RISK FACTOR; STAPHYLOCOCCUS INFECTION;

ADOPTIVE TRANSFER; ANIMALS; BLOOD COAGULATION; COMPLEMENT PATHWAY, MANNOSE-BINDING LECTIN; DISEASE SUSCEPTIBILITY; DISSEMINATED INTRAVASCULAR COAGULATION; INTERLEUKIN-6; LIVER; MANNOSE-BINDING LECTIN; MANNOSE-BINDING PROTEIN-ASSOCIATED SERINE PROTEASES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; RISK FACTORS; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS; THROMBIN;

EID: 78649500126     PISSN: 01712985     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.imbio.2010.02.005     Document Type: Article

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