Isoliquiritigenin showed strong inhibitory effects towards multiple UDP-glucuronosyltransferase (UGT) isoform-catalyzed 4-methylumbelliferone (4-MU) glucuronidation

Fitoterapia

Volumn 84, Issue 1, 2013, Pages 208-212

  Lu, Hang ^a   Fang, Zhong Ze ^b,d   Cao, Yun Feng ^b,c   Hu, Cui Min ^d   Hong, Mo ^b   Sun, Xiao Yu ^b   Li, Hua ^a   Liu, Yan ^a   Fu, Xiaoguang ^a   Sun, Hongzhi ^a  

^a JINZHOU MEDICAL UNIVERSITY   (China)

^b DALIAN INSTITUTE OF CHEMICAL PHYSICS   (China)

^c SHANGHAI INSTITUTE OF PLANNED PARENTHOOD RESEARCH   (China)

^d NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Enzyme inhibition; Isoliquiritigenin; UDP glucuronosyltransferase (UGT)

Indexed keywords

GLUCURONOSYLTRANSFERASE; GLUCURONOSYLTRANSFERASE 1A1; GLUCURONOSYLTRANSFERASE 1A10; GLUCURONOSYLTRANSFERASE 1A3; GLUCURONOSYLTRANSFERASE 1A6; GLUCURONOSYLTRANSFERASE 1A7; GLUCURONOSYLTRANSFERASE 1A8; GLUCURONOSYLTRANSFERASE 1A9; HYMECROMONE; ISOLIQUIRITIGENIN;

ARTICLE; CATALYST; CHEMICAL REACTION; COMPETITIVE INHIBITION; CONTROLLED STUDY; DRUG GLUCURONIDATION; ENZYME ACTIVITY; ENZYME INHIBITION; KINETICS; LIMIT OF DETECTION; PLOTS AND CURVES; PRIORITY JOURNAL;

CHALCONES; GLUCURONOSYLTRANSFERASE; HYMECROMONE; PROTEIN ISOFORMS;

EID: 84873370253     PISSN: 0367326X     EISSN: 18736971     Source Type: Journal    
DOI: 10.1016/j.fitote.2012.12.002     Document Type: Article

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