Modeling complex equilibria in isothermal titration calorimetry experiments: Thermodynamic parameters estimation for a three-binding-site model

Analytical Biochemistry

Volumn 434, Issue 2, 2013, Pages 233-241

  Le, Vu H ^a   Buscaglia, Robert ^b   Chaires, Jonathan B ^b   Lewis, Edwin A ^a  

^a MISSISSIPPI STATE UNIVERSITY   (United States)

^b University of Louisville School of Medicine   (United States)

Author keywords

Analysis; Calorimetry; Fitting; ITC; Multiple binding sites; Nonlinear regression; Three binding site model

Indexed keywords

BINDING ENERGY; CALORIMETERS; CALORIMETRY; EQUILIBRIUM CONSTANTS; ISOTHERMS; LIGANDS; MATLAB; REGRESSION ANALYSIS; SITE SELECTION; THERMODYNAMIC PROPERTIES; TITRATION;

ANALYSIS; BINDING SITE MODELS; FITTING; MULTIPLE BINDING SITES; NON-LINEAR REGRESSION;

BINDING SITES;

ALGORITHM; ANALYTICAL ERROR; ARTICLE; BINDING SITE; CHEMICAL INTERACTION; COMPUTER PROGRAM; EQUILIBRIUM CONSTANT; ISOTHERMAL TITRATION CALORIMETRY; LIGAND BINDING; MACROMOLECULE; MODEL; MONTE CARLO METHOD; NONLINEAR REGRESSION ANALYSIS; PRIORITY JOURNAL; THERMODYNAMICS;

EID: 84873348065     PISSN: 00032697     EISSN: 10960309     Source Type: Journal    
DOI: 10.1016/j.ab.2012.11.030     Document Type: Article

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