Airway epithelium is a predominant source of endogenous airway GABA and contributes to relaxation of airway smooth muscle tone

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 304, Issue 3, 2013, Pages

  Gallos, George ^a   Townsend, Elizabeth ^a   Yim, Peter ^a   Virag, Laszlo ^a   Zhang, Yi ^a   Xu, Dingbang ^a   Bacchetta, Matthew ^a   Emala, Charles W ^a  

^a College of Physicians and Surgeons of Columbia University ^*  (United States)

Author keywords

Airway; Epithelial; GABA; Tone

Indexed keywords

4 AMINOBUTYRIC ACID; ACETYLCHOLINE; MESSENGER RNA; TETRODOTOXIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL STIMULATION; CONTROLLED STUDY; GABAERGIC SYSTEM; GUINEA PIG; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PARACRINE SIGNALING; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; RESPIRATORY EPITHELIUM; SMOOTH MUSCLE FIBER; SMOOTH MUSCLE RELAXATION; SMOOTH MUSCLE TONE;

ACETYLCHOLINE; ANIMALS; CHOLINERGIC AGONISTS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; GABA PLASMA MEMBRANE TRANSPORT PROTEINS; GABA UPTAKE INHIBITORS; GAMMA-AMINOBUTYRIC ACID; GENE EXPRESSION; GLUTAMATE DECARBOXYLASE; GUINEA PIGS; HUMANS; MUSCLE CONTRACTION; MUSCLE RELAXATION; MUSCLE TONUS; MUSCLE, SMOOTH; ORGAN CULTURE TECHNIQUES; RESPIRATORY MUCOSA; RNA, MESSENGER; TETRODOTOXIN; TRACHEA;

EID: 84873330567     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00274.2012     Document Type: Article

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