Synthetic studies on CP-225,917 and CP-263,114: Access to advanced tetracyclic systems by intramolecular conjugate displacement and [2,3]-wittig rearrangement

Journal of Organic Chemistry

Volumn 78, Issue 3, 2013, Pages 996-1013

  Malihi, Farzad ^a   Clive, Derrick L J ^a   Chang, Che Chien ^a   Minaruzzaman, ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

SYNTHETIC STUDY; WITTIG REARRANGEMENT;

CHEMISTRY;

ORGANIC COMPOUNDS;

2 (CYCLOHEX 1 EN 1 YLMETHOXY)ACETIC ACID; 2 HYDROXY 2 (2 METHYLIDENECYCLOHEXYL)ACETIC ACID; 3 HYDROXY 10 [2 [(2 METHOXYETHOXY)METHOXY]ETHYL] 9 [(TRIETHYLSILYL)OXY] 4 OXATRICYLCO[5.2.1.0 3,8]DECAN 2 ONE; 3 HYDROXY 7A (IODOMETHYL)OCTAHYDRO 1 BENZOFURAN 2 ONE; 7A (IODOMETHYL) 3 [(TRIETHYLSILYL)OXY]OCTAHYDRO 1 BENZOFURAN 2 ONE; 9 [2 [(TERT BUTYLDIMETHYLSILYL)OXY]ETHYL] 15 METHOXY 6 [2 [(2 METHOXYETHOXY)METHOXY]ETHYL] 11 METHYLIDENE 2,14 DIOXATETRACYCLO[7.4.2.0 1,8.0 5,13]PENTADEC 7 EN 12 YL]METHOXY]TRIETHYLSILANE; 9 [2 [(TERT BUTYLDIMETHYLSILYL)OXY]ETHYL] 15 METHOXY 6 [2 [(2 METHOXYETHOXY)METHOXY]ETHYL] 2,14 DIOXATETRACYCLO[7.4.2.0 1,8.0 5,13]PENTADECA 7,11 DIEN 11 YL]METHYL 2 [(TERT BUTYLDIMETHYLSILYL)OXY]ACETATE; CP 225 917; CP 263 114; METHYL 2 HYDROXY 2 [1 OXASPIRO[2.5]OCTAN 4 YL]ACETATE; NATURAL PRODUCT; TERT BUTYL [2 (15 METHOXY 6 [2 [(2 METHOXYETHOXY)METHOXY]ETHYL] 11 [[(TRIBUTYLSTANNYL) METHOXY]METHYL] 2,14 DIOXATETRACYCLO[7.4.2.0 1,8 .0 5,13]PENTADECA 7,11 DIEN 9 YL)ETHOXY]DIPHENYLSILANE; UNCLASSIFIED DRUG;

ALKYLATION; ARTICLE; BAYLIS HILLMAN REACTION; CARBON NUCLEAR MAGNETIC RESONANCE; CRYSTAL STRUCTURE; CYCLOADDITION; DIELS ALDER REACTION; DRUG STRUCTURE; DRUG SYNTHESIS; ISOMERIZATION; SILYLATION; STEREOCHEMISTRY; WITTIG REARRANGEMENT;

HETEROCYCLIC COMPOUNDS WITH 4 OR MORE RINGS; MAGNETIC RESONANCE SPECTROSCOPY; MALEIC ANHYDRIDES; STEREOISOMERISM;

EID: 84873330308     PISSN: 00223263     EISSN: 15206904     Source Type: Journal    
DOI: 10.1021/jo302467w     Document Type: Article

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