Synthesis and biological evaluation of conformationally restricted gabapentin analogues

Bioorganic and Medicinal Chemistry Letters

Volumn 9, Issue 16, 1999, Pages 2329-2334

  Receveur, Jean Marie ^a   Bryans, Justin S ^a   Field, Mark J ^a   Singh, Lakhbir ^a   Horwell, David C ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

2 AZA SPIRO[4.5]DECANE 4 CARBOXYLIC ACID; 4 AMINOBUTYRIC ACID; ANTICONVULSIVE AGENT; CALCIUM CHANNEL; CARRAGEENAN; GABAPENTIN; GABAPENTIN DERIVATIVE; PYRROLIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG BINDING SITE; DRUG CONFORMATION; DRUG EFFECT; DRUG SYNTHESIS; HYPERALGESIA; NONHUMAN; RAT; REACTION ANALYSIS;

ACETIC ACIDS; AMINES; ANALGESICS, NON-NARCOTIC; ANIMALS; CONVULSANTS; CYCLOHEXANECARBOXYLIC ACIDS; GAMMA-AMINOBUTYRIC ACID; MOLECULAR STRUCTURE; RATS;

EID: 0033575678     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(99)00383-2     Document Type: Article

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