-
2
-
-
0018171211
-
Differentiation of epithelial foot processes and filtration slits: Sequential appearance of occluding junctions, epithelial polyanion, and slit membranes in developing glomeruli
-
Reeves W, Caulfield JP, Farquhar MG: Differentiation of epithelial foot processes and filtration slits: Sequential appearance of occluding junctions, epithelial polyanion, and slit membranes in developing glomeruli. Lab Invest 39:90-100, 1978
-
(1978)
Lab Invest
, vol.39
, pp. 90-100
-
-
Reeves, W.1
Caulfield, J.P.2
Farquhar, M.G.3
-
3
-
-
33751161268
-
The cellular basis of kidney development
-
Dressler GR: The cellular basis of kidney development. Annu Rev Cell Dev Biol 22:509-529, 2006
-
(2006)
Annu Rev Cell Dev Biol
, vol.22
, pp. 509-529
-
-
Dressler, G.R.1
-
4
-
-
34447123177
-
Ontogenetic development of the filtration barrier
-
Kriz W: Ontogenetic development of the filtration barrier. Nephron, Exp Nephrol 106:e44-e50, 2007
-
(2007)
Nephron, Exp Nephrol
, vol.106
-
-
Kriz, W.1
-
5
-
-
38149090050
-
How do mesangial and endothelial cells form the glomerular tuft?
-
Vaughan MR, Quaggin SE: How do mesangial and endothelial cells form the glomerular tuft? J Am Soc Nephrol 19:24-33, 2008
-
(2008)
J Am Soc Nephrol
, vol.19
, pp. 24-33
-
-
Vaughan, M.R.1
Quaggin, S.E.2
-
7
-
-
79954546158
-
Protein complexes that control renal epithelial polarity
-
Pieczynski J, Margolis B: Protein complexes that control renal epithelial polarity. Am J Physiol Renal Physiol 300:F589-F601, 2011
-
(2011)
Am J Physiol Renal Physiol
, vol.300
-
-
Pieczynski, J.1
Margolis, B.2
-
8
-
-
53149104790
-
Neph-Nephrin proteins bind the Par3-Par6-atypical protein kinase C (aPKC) complex to regulate podocyte cell polarity
-
Hartleben B, Schweizer H, Lübben P, Bartram MP, Möller CC, Herr R, Wei C, Neumann-Haefelin E, Schermer B, Zentgraf H, Kerjaschki D, Reiser J, Walz G, Benzing T, Huber TB: Neph-Nephrin proteins bind the Par3-Par6-atypical protein kinase C (aPKC) complex to regulate podocyte cell polarity. J Biol Chem 283:23033-23038, 2008
-
(2008)
J Biol Chem
, vol.283
, pp. 23033-23038
-
-
Hartleben, B.1
Schweizer, H.2
Lübben, P.3
Bartram, M.P.4
Möller, C.C.5
Herr, R.6
Wei, C.7
Neumann-Haefelin, E.8
Schermer, B.9
Zentgraf, H.10
Kerjaschki, D.11
Reiser, J.12
Walz, G.13
Benzing, T.14
Huber, T.B.15
-
9
-
-
65249087940
-
Loss of podocyte aPKClambda/iota causes polarity defects and nephrotic syndrome
-
Huber TB, Hartleben B, Winkelmann K, Schneider L, Becker JU, Leitges M, Walz G, Haller H, Schiffer M: Loss of podocyte aPKClambda/iota causes polarity defects and nephrotic syndrome. J AmSoc Nephrol 20:798-806, 2009
-
(2009)
J AmSoc Nephrol
, vol.20
, pp. 798-806
-
-
Huber, T.B.1
Hartleben, B.2
Winkelmann, K.3
Schneider, L.4
Becker, J.U.5
Leitges, M.6
Walz, G.7
Haller, H.8
Schiffer, M.9
-
10
-
-
58449096160
-
An essential role of the universal polarity protein, aPKClambda, on the maintenance of podocyte slit diaphragms
-
Hirose T, Satoh D, Kurihara H, Kusaka C, Hirose H, Akimoto K, Matsusaka T, Ichikawa I, Noda T, Ohno S: An essential role of the universal polarity protein, aPKClambda, on the maintenance of podocyte slit diaphragms. PLoS ONE 4:e4194, 2009
-
(2009)
PLoS ONE
, vol.4
-
-
Hirose, T.1
Satoh, D.2
Kurihara, H.3
Kusaka, C.4
Hirose, H.5
Akimoto, K.6
Matsusaka, T.7
Ichikawa, I.8
Noda, T.9
Ohno, S.10
-
11
-
-
0034253536
-
The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42
-
Joberty G, Petersen C, Gao L, Macara IG: The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42. Nat Cell Biol 2:531-539, 2000
-
(2000)
Nat Cell Biol
, vol.2
, pp. 531-539
-
-
Joberty, G.1
Petersen, C.2
Gao, L.3
Macara, I.G.4
-
12
-
-
0034659420
-
A human homolog of the C. elegans polarity determinant Par-6 links Rac and Cdc42 to PKCzeta signaling and cell transformation
-
Qiu RG, Abo A, Steven Martin G: A human homolog of the C. elegans polarity determinant Par-6 links Rac and Cdc42 to PKCzeta signaling and cell transformation. Curr Biol 10:697-707, 2000
-
(2000)
Curr Biol
, vol.10
, pp. 697-707
-
-
Qiu, R.G.1
Abo, A.2
Martin, G.S.3
-
13
-
-
0000202186
-
A mammalian PAR-3-PAR-6 complex implicated in Cdc42/Rac1 and aPKC signalling and cell polarity
-
Lin D, Edwards AS, Fawcett JP, Mbamalu G, Scott JD, Pawson T: A mammalian PAR-3-PAR-6 complex implicated in Cdc42/Rac1 and aPKC signalling and cell polarity. Nat Cell Biol 2:540-547, 2000
-
(2000)
Nat Cell Biol
, vol.2
, pp. 540-547
-
-
Lin, D.1
Edwards, A.S.2
Fawcett, J.P.3
Mbamalu, G.4
Scott, J.D.5
Pawson, T.6
-
14
-
-
0034874862
-
PAR-6 regulates aPKC activity in a novel way and mediates cell-cell contact-induced formation of the epithelial junctional complex
-
Yamanaka T, Horikoshi Y, Suzuki A, Sugiyama Y, Kitamura K, Maniwa R, Nagai Y, Yamashita A, Hirose T, Ishikawa H, Ohno S: PAR-6 regulates aPKC activity in a novel way and mediates cell-cell contact-induced formation of the epithelial junctional complex. Genes Cells 6:721-731, 2001
-
(2001)
Genes Cells
, vol.6
, pp. 721-731
-
-
Yamanaka, T.1
Horikoshi, Y.2
Suzuki, A.3
Sugiyama, Y.4
Kitamura, K.5
Maniwa, R.6
Nagai, Y.7
Yamashita, A.8
Hirose, T.9
Ishikawa, H.10
Ohno, S.11
-
15
-
-
0037287298
-
Protein kinase C lambda/iota (PKClambda/iota): A PKC isotype essential for the development of multicellular organisms
-
Suzuki A, Akimoto K, Ohno S: Protein kinase C lambda/iota (PKClambda/iota): A PKC isotype essential for the development of multicellular organisms. J Biochem 133:9-16, 2003
-
(2003)
J Biochem
, vol.133
, pp. 9-16
-
-
Suzuki, A.1
Akimoto, K.2
Ohno, S.3
-
16
-
-
4344652068
-
Targeted deletion of protein kinase C lambda reveals a distribution of functions between the two atypical protein kinase C isoforms
-
Soloff RS, Katayama C, Lin MY, Feramisco JR, Hedrick SM: Targeted deletion of protein kinase C lambda reveals a distribution of functions between the two atypical protein kinase C isoforms. J Immunol 173:3250-3260, 2004
-
(2004)
J Immunol
, vol.173
, pp. 3250-3260
-
-
Soloff, R.S.1
Katayama, C.2
Lin, M.Y.3
Feramisco, J.R.4
Hedrick, S.M.5
-
17
-
-
13944253118
-
Targeted disruption of the zetaPKC gene results in the impairment of the NF-kappaB pathway
-
Leitges M, Sanz L, Martin P, Duran A, Braun U, García JF, Camacho F, Diaz-Meco MT, Rennert PD, Moscat J: Targeted disruption of the zetaPKC gene results in the impairment of the NF-kappaB pathway. Mol Cell 8:771-780, 2001
-
(2001)
Mol Cell
, vol.8
, pp. 771-780
-
-
Leitges, M.1
Sanz, L.2
Martin, P.3
Duran, A.4
Braun, U.5
García, J.F.6
Camacho, F.7
Diaz-Meco, M.T.8
Rennert, P.D.9
Moscat, J.10
-
18
-
-
34547663520
-
Musclespecific knockout of PKC-lambda impairs glucose transport and induces metabolic and diabetic syndromes
-
Farese RV, Sajan MP, Yang H, Li P, Mastorides S, Gower WR Jr, Nimal S, Choi CS, Kim S, Shulman GI, Kahn CR, Braun U, Leitges M: Musclespecific knockout of PKC-lambda impairs glucose transport and induces metabolic and diabetic syndromes. J Clin Invest 117:2289-2301, 2007
-
(2007)
J Clin Invest
, vol.117
, pp. 2289-2301
-
-
Farese, R.V.1
Sajan, M.P.2
Yang, H.3
Li, P.4
Mastorides, S.5
Gower Jr., W.R.6
Nimal, S.7
Choi, C.S.8
Kim, S.9
Shulman, G.I.10
Kahn, C.R.11
Braun, U.12
Leitges, M.13
-
19
-
-
0037247603
-
Podocytespecific expression of cre recombinase in transgenic mice
-
Moeller MJ, Sanden SK, Soofi A, Wiggins RC, Holzman LB: Podocytespecific expression of cre recombinase in transgenic mice. Genesis 35:39-42, 2003
-
(2003)
Genesis
, vol.35
, pp. 39-42
-
-
Moeller, M.J.1
Sanden, S.K.2
Soofi, A.3
Wiggins, R.C.4
Holzman, L.B.5
-
20
-
-
23644449576
-
Centrosome localization determines neuronal polarity
-
de Anda FC, Pollarolo G, Da Silva JS, Camoletto PG, Feiguin F, Dotti CG: Centrosome localization determines neuronal polarity. Nature 436:704-708, 2005
-
(2005)
Nature
, vol.436
, pp. 704-708
-
-
De Anda, F.C.1
Pollarolo, G.2
Da Silva, J.S.3
Camoletto, P.G.4
Feiguin, F.5
Dotti, C.G.6
-
21
-
-
4143082698
-
Differential expression of atypical PKCs in the adult mouse brain
-
Oster H, Eichele G, Leitges M: Differential expression of atypical PKCs in the adult mouse brain. Brain Res Mol Brain Res 127:79-88, 2004
-
(2004)
Brain Res Mol Brain Res
, vol.127
, pp. 79-88
-
-
Oster, H.1
Eichele, G.2
Leitges, M.3
-
22
-
-
33947191092
-
Role of aPKC isoforms and their binding partners Par3 and Par6 in epidermal barrier formation
-
Helfrich I, Schmitz A, Zigrino P, Michels C, Haase I, le Bivic A, Leitges M, Niessen CM: Role of aPKC isoforms and their binding partners Par3 and Par6 in epidermal barrier formation. J Invest Dermatol 127:782-791, 2007
-
(2007)
J Invest Dermatol
, vol.127
, pp. 782-791
-
-
Helfrich, I.1
Schmitz, A.2
Zigrino, P.3
Michels, C.4
Haase, I.5
Le Bivic, A.6
Leitges, M.7
Niessen, C.M.8
-
23
-
-
79959968305
-
Atypical protein kinase C (aPKCzeta and aPKClambda) is dispensable for mammalian hematopoietic stemcell activity and blood formation
-
Sengupta A, Duran A, Ishikawa E, Florian MC, Dunn SK, Ficker AM, Leitges M, Geiger H, Diaz-Meco M, Moscat J, Cancelas JA: Atypical protein kinase C (aPKCzeta and aPKClambda) is dispensable for mammalian hematopoietic stemcell activity and blood formation. Proc Natl Acad Sci U S A 108:9957-9962, 2011
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 9957-9962
-
-
Sengupta, A.1
Duran, A.2
Ishikawa, E.3
Florian, M.C.4
Dunn, S.K.5
Ficker, A.M.6
Leitges, M.7
Geiger, H.8
Diaz-Meco, M.9
Moscat, J.10
Cancelas, J.A.11
-
24
-
-
0347986678
-
Early glomerular filtration defect and severe renal disease in podocindeficient mice
-
Roselli S, Heidet L, Sich M, Henger A, Kretzler M, Gubler MC, Antignac C: Early glomerular filtration defect and severe renal disease in podocindeficient mice. Mol Cell Biol 24:550-560, 2004
-
(2004)
Mol Cell Biol
, vol.24
, pp. 550-560
-
-
Roselli, S.1
Heidet, L.2
Sich, M.3
Henger, A.4
Kretzler, M.5
Gubler, M.C.6
Antignac, C.7
-
25
-
-
0035164681
-
The murine nephrin gene is specifically expressed in kidney, brain and pancreas: Inactivation of the gene leads to massive proteinuria and neonatal death
-
Putaala H, Soininen R, Kilpeläinen P, Wartiovaara J, Tryggvason K: The murine nephrin gene is specifically expressed in kidney, brain and pancreas: Inactivation of the gene leads to massive proteinuria and neonatal death. Hum Mol Genet 10:1-8, 2001
-
(2001)
Hum Mol Genet
, vol.10
, pp. 1-8
-
-
Putaala, H.1
Soininen, R.2
Kilpeläinen, P.3
Wartiovaara, J.4
Tryggvason, K.5
-
26
-
-
0034948819
-
Proteinuria and perinatal lethality in mice lacking NEPH1, a novel protein with homology to NEPHRIN
-
Donoviel DB, Freed DD, Vogel H, Potter DG, Hawkins E, Barrish JP, Mathur BN, Turner CA, Geske R, Montgomery CA, Starbuck M, Brandt M, Gupta A, Ramirez-Solis R, Zambrowicz BP, Powell DR: Proteinuria and perinatal lethality in mice lacking NEPH1, a novel protein with homology to NEPHRIN. Mol Cell Biol 21:4829-4836, 2001
-
(2001)
Mol Cell Biol
, vol.21
, pp. 4829-4836
-
-
Donoviel, D.B.1
Freed, D.D.2
Vogel, H.3
Potter, D.G.4
Hawkins, E.5
Barrish, J.P.6
Mathur, B.N.7
Turner, C.A.8
Geske, R.9
Montgomery, C.A.10
Starbuck, M.11
Brandt, M.12
Gupta, A.13
Ramirez-Solis, R.14
Zambrowicz, B.P.15
Powell, D.R.16
-
27
-
-
0037428076
-
Hippocampal neuronal polarity specified by spatially localized mPar3/mPar6 and PI 3-kinase activity
-
Shi SH, Jan LY, Jan YN: Hippocampal neuronal polarity specified by spatially localized mPar3/mPar6 and PI 3-kinase activity. Cell 112:63-75, 2003
-
(2003)
Cell
, vol.112
, pp. 63-75
-
-
Shi, S.H.1
Jan, L.Y.2
Jan, Y.N.3
-
29
-
-
33644747349
-
The polarity protein PAR-3 and TIAM1 cooperate in dendritic spine morphogenesis
-
Zhang H, Macara IG: The polarity protein PAR-3 and TIAM1 cooperate in dendritic spine morphogenesis. Nat Cell Biol 8:227-237, 2006
-
(2006)
Nat Cell Biol
, vol.8
, pp. 227-237
-
-
Zhang, H.1
Macara, I.G.2
-
30
-
-
38849119148
-
The PAR-6 polarity protein regulates dendritic spinemorphogenesis through p190 RhoGAP and the RhoGTPase
-
Zhang H, Macara IG: The PAR-6 polarity protein regulates dendritic spinemorphogenesis through p190 RhoGAP and the RhoGTPase. Dev Cell 14:216-226, 2008
-
(2008)
Dev Cell
, vol.14
, pp. 216-226
-
-
Zhang, H.1
Macara, I.G.2
-
31
-
-
0035943401
-
Integrin-mediated activation of Cdc42 controls cell polarity in migrating astrocytes through PKCzeta
-
Etienne-Manneville S, Hall A: Integrin-mediated activation of Cdc42 controls cell polarity in migrating astrocytes through PKCzeta. Cell 106:489-498, 2001
-
(2001)
Cell
, vol.106
, pp. 489-498
-
-
Etienne-Manneville, S.1
Hall, A.2
-
32
-
-
84863534353
-
-
Scott RP, Hawley SP, Ruston J, Du J, Brakebusch C, Jones N, Pawson T: Podocyte-specific loss of Cdc42 leads to congenital nephropathy. JAm Soc Nephrol 23:1149-1154, 2012
-
(2012)
Podocyte-specific Loss of Cdc42 Leads to Congenital Nephropathy. JAm Soc Nephrol
, vol.23
, pp. 1149-1154
-
-
Scott, R.P.1
Hawley, S.P.2
Ruston, J.3
Du, J.4
Brakebusch, C.5
Jones, N.6
Pawson, T.7
-
33
-
-
0037370325
-
Glomerular-specific alterations of VEGF-A expression lead to distinct congenital and acquired renal diseases
-
Eremina V, Sood M, Haigh J, Nagy A, Lajoie G, Ferrara N, Gerber HP, Kikkawa Y, Miner JH, Quaggin SE: Glomerular-specific alterations of VEGF-A expression lead to distinct congenital and acquired renal diseases. J Clin Invest 111:707-716, 2003
-
(2003)
J Clin Invest
, vol.111
, pp. 707-716
-
-
Eremina, V.1
Sood, M.2
Haigh, J.3
Nagy, A.4
Lajoie, G.5
Ferrara, N.6
Gerber, H.P.7
Kikkawa, Y.8
Miner, J.H.9
Quaggin, S.E.10
-
34
-
-
0031668536
-
Paracrine PDGF-B/PDGF-Rbeta signaling controls mesangial cell development in kidney glomeruli
-
Lindahl P, Hellström M, Kalén M, Karlsson L, Pekny M, Pekna M, Soriano P, Betsholtz C: Paracrine PDGF-B/PDGF-Rbeta signaling controls mesangial cell development in kidney glomeruli. Development 125:3313-3322, 1998
-
(1998)
Development
, vol.125
, pp. 3313-3322
-
-
Lindahl, P.1
Hellström, M.2
Kalén, M.3
Karlsson, L.4
Pekny, M.5
Pekna, M.6
Soriano, P.7
Betsholtz, C.8
-
35
-
-
0344921338
-
Mesangial cells organize the glomerular capillaries by adhering to the G domain of laminin alpha5 in the glomerular basement membrane
-
Kikkawa Y, Virtanen I, Miner JH: Mesangial cells organize the glomerular capillaries by adhering to the G domain of laminin alpha5 in the glomerular basement membrane. J Cell Biol 161:187-196, 2003
-
(2003)
J Cell Biol
, vol.161
, pp. 187-196
-
-
Kikkawa, Y.1
Virtanen, I.2
Miner, J.H.3
-
36
-
-
40849130173
-
VEGF inhibition and renal thrombotic microangiopathy
-
Eremina V, Jefferson JA, Kowalewska J, Hochster H, Haas M, Weisstuch J, Richardson C, Kopp JB, Kabir MG, Backx PH, Gerber HP, Ferrara N, Barisoni L, Alpers CE, Quaggin SE: VEGF inhibition and renal thrombotic microangiopathy. N Engl J Med 358:1129-1136, 2008
-
(2008)
N Engl J Med
, vol.358
, pp. 1129-1136
-
-
Eremina, V.1
Jefferson, J.A.2
Kowalewska, J.3
Hochster, H.4
Haas, M.5
Weisstuch, J.6
Richardson, C.7
Kopp, J.B.8
Kabir, M.G.9
Backx, P.H.10
Gerber, H.P.11
Ferrara, N.12
Barisoni, L.13
Alpers, C.E.14
Quaggin, S.E.15
-
37
-
-
0036733653
-
A new method for large scale isolation of kidney glomeruli from mice
-
Takemoto M, Asker N, Gerhardt H, Lundkvist A, Johansson BR, Saito Y, Betsholtz C: A new method for large scale isolation of kidney glomeruli from mice. Am J Pathol 161:799-805, 2002
-
(2002)
Am J Pathol
, vol.161
, pp. 799-805
-
-
Takemoto, M.1
Asker, N.2
Gerhardt, H.3
Lundkvist, A.4
Johansson, B.R.5
Saito, Y.6
Betsholtz, C.7
|