|
|
Volumn 21, Issue 4, 2013, Pages 993-1005
|
|
Structure-activity relationship of benzodiazepine derivatives as LXXLL peptide mimetics that inhibit the interaction of vitamin D receptor with coactivators
|
|
Author keywords
Antagonist; Cofactor; LXXLL; Non peptide; Nuclear receptor; Protein interaction inhibitor; Structure activity relationship; Vitamin D
|
|
Indexed keywords
1,2,4,5 TETRAHYDRO 2 (2 METHYLPROPYL) 3H 1,4 BENZODIAZEPIN 3 ONE;
1,2,4,5 TETRAHYDRO 4 (3 METHYLBUTYL) 2 (2 METHYLPROPYL) 3H 1,4 BENZODIAZEPIN 3 ONE;
1,2,4,5 TETRAHYDRO 4 (3 METHYLBUTYL) 2,7 DI(2 METHYLPROPYL) 3H 1,4 BENZODIAZEPIN 3 ONE;
1,2,4,5 TETRAHYDRO 4 (3 METHYLBUTYL) 7 (2 METHYLPROPYL 1 ENYL) 2 (2 METHYLPROPYL) 3H 1,4 BENZODIAZEPIN 3 ONE;
1,2,4,5 TETRAHYDRO 7 (3 HYDROXYPROP 1 ENYL) 4 (3 METHYLBUTYL) 2 (2 METHYLPROPYL) 3H 1,4 BENZODIAZEPIN 3 ONE;
1,2,4,5 TETRAHYDRO 7 (3 HYDROXYPROPYL) 4 (3 METHYLBUTYL) 2 (2 METHYLPROPYL) 3H 1,4 BENZODIAZEPIN 3 ONE;
1,2,4,5 TETRAHYDRO 7 (4 HYDROXYBUT 1 ENYL) 4 (3 METHYLBUTYL) 2 (2 METHYLPROPYL) 3H 1,4 BENZODIAZEPIN 3 ONE;
1,2,4,5 TETRAHYDRO 7 (4 HYDROXYBUTYL) 4 (3 METHYLBUTYL) 2 (2 METHYLPROPYL) 3H 1,4 BENZODIAZEPIN 3 ONE;
1,2,4,5 TETRAHYDRO 7 [4 (TERT BUTYLDIMETHYLSILYLOXY)BUTYL] 4 (3 METHYLBUTYL) 2 (2 METHYLPROPYL) 3H 1,4 BENZODIAZEPIN 3 ONE;
1,2,4,5 TETRAHYDRO 7 IODO 4 (3 METHYLBUTYL) 2 (2 METHYLPROPYL) 3H 1,4 BENZODIAZEPIN 3 ONE;
3 (TERT BUTYLDIMETHYLSILYLOXY)PROP 1 ENYLBORONIC ACID;
4 (TERT BUTYLDIMETHYLSILYLOXY)BUT 1 ENYLBORONIC ACID;
7 (BUT 1 ENYL) 1,2,4,5 TETRAHYDRO 4 (3 METHYLBUTYL) 2 (2 METHYLPROPYL) 3H 1,4 BENZODIAZEPIN 3 ONE;
8 AMINO 1,2,4,5 TETRAHYDRO 4 (3 METHYLBUTYL) 2 (2 METHYLPROPYL) 7 PENTYL 3H 1,4 BENZODIAZEPIN 3 ONE;
8 AMINO 4 (3 METHYLBUTYL) 2 (2 METHYLPROPYL) 1,2,4,5 TETRAHYDRO 7 (PENT 1 ENYL) 3H 1,4 BENZODIAZEPIN 3 ONE;
8 AMINO 4 (3 METHYLBUTYL) 2 (2 METHYLPROPYL) 1,2,4,5 TETRAHYDROHYDRO 7 PENTYL 3H 1,4 BENZODIAZEPIN 3 ONE;
8 AMINO 7 BUTYL 4 (3 METHYLBUTYL) 2 (2 METHYLPROPYL) 1,2,4,5 TETRAHYDROHYDRO 3H 1,4 BENZODIAZEPIN 3 ONE;
8 BIS(TERT BUTOXYCARBONYL)AMINO 1,2,4,5 TETRAHYDRO 2 (2 METHYLPROPYL) 3H 1,4 BENZODIAZEPIN 3 ONE;
8 BIS(TERT BUTOXYCARBONYL)AMINO 1,2,4,5 TETRAHYDRO 4 (3 METHYLBUT 2 ENYL) 2 (2 METHYLPROPYL) 3H 1,4 BENZODIAZEPIN 3 ONE;
BENZODIAZEPINE DERIVATIVE;
ETHYL 3 [2 (BENZYLOXY)ETHOXY] 4 IODOBENZOATE;
ETHYL 3 HYDROXY 4 IODOBENZOATE;
ETHYL 4 [8 AMINO 1,2,4,5 TETRAHYDRO 2 (2 METHYLPROPYL) 4 (3 METHYLBUTYL) 3 OXO 3H 1,4 BENZODIAZEPIN 7 YL] 3 (2 HYDROXYETHOXY)BENZOATE;
ETHYL 4 [8 AMINO 1,2,4,5 TETRAHYDRO 2 (2 METHYLPROPYL) 4 (3 METHYLBUTYL) 3 OXO 3H 1,4 BENZODIAZEPIN 7 YL] 3 [2 (BENZYLOXY)ETHOXY]BENZOATE;
ETHYL 4 [8 AMINO 1,2,4,5 TETRAHYDRO 2 (2 METHYLPROPYL) 4 (3 METHYLBUTYL) 3 OXO 3H 1,4 BENZODIAZEPIN 7 YL]BENZOATE;
LXXLL PEPTIDE;
NUCLEAR RECEPTOR COACTIVATOR;
PEPTIDE DERIVATIVE;
UNCLASSIFIED DRUG;
UNINDEXED DRUG;
VITAMIN D RECEPTOR;
ARTICLE;
CONTROLLED STUDY;
DRUG DESIGN;
DRUG MECHANISM;
DRUG SYNTHESIS;
HUMAN;
HUMAN CELL;
HYDROGEN BOND;
PROTEIN FUNCTION;
PROTEIN PROTEIN INTERACTION;
STRUCTURE ACTIVITY RELATION;
STRUCTURE ANALYSIS;
AMINO ACID SEQUENCE;
BENZODIAZEPINES;
BINDING SITES;
BIOMIMETIC MATERIALS;
MOLECULAR DOCKING SIMULATION;
PEPTIDES;
PROTEIN BINDING;
PROTEIN STRUCTURE, TERTIARY;
RECEPTORS, CALCITRIOL;
STRUCTURE-ACTIVITY RELATIONSHIP;
TRANSCRIPTIONAL ACTIVATION;
|
|
EID: 84873320439
PISSN: 09680896
EISSN: 14643391
Source Type: Journal
DOI: 10.1016/j.bmc.2012.11.042 Document Type: Article |
|
Times cited : (26)
|
|
References (20)
|
