Liposomal-benzocaine gel formulation: Correlation between in vitro assays and in vivo topical anesthesia in volunteers

Journal of Liposome Research

Volumn 23, Issue 1, 2013, Pages 54-60

  Franz Montan, Michelle ^a   Cereda, Cintia Maria Saia ^a   Gaspari, Adele ^c   Da Silva, Camila Morais Gonçalves ^a   De Araújo, Daniele Ribeiro ^a,b   Padula, Cristina ^c   Santi, Patrizia ^c   Narvaes, Eliene ^a   Novaes, Pedro Duarte ^a   Groppo, Francisco Carlos ^a   De Paula, Eneida ^a  

^a UNIVERSITY OF CAMPINAS   (Brazil)

^b UNIVERSIDADE FEDERAL DO ABC   (Brazil)

^c UNIVERSITY OF PARMA   (Italy)

Author keywords

Anesthetic efficacy; Benzocaine; Oral mucosa; Permeation; Retention

Indexed keywords

BENZOCAINE; LIPOSOME;

ANALGESIA; ANALGESIC ACTIVITY; ANIMAL TISSUE; ARTICLE; DRUG ABSORPTION; DRUG EFFICACY; DRUG FORMULATION; DRUG PENETRATION; DRUG RELEASE; DRUG RETENTION; DRUG SOLUBILITY; DRUG TRANSPORT; ENCAPSULATION; ESOPHAGUS MUCOSA; GEL; GEL FORMULATION; HUMAN; IN VITRO STUDY; IN VIVO STUDY; LAMINA PROPRIA; LIMIT OF DETECTION; LIMIT OF QUANTITATION; LIPID MEMBRANE; LIPOPHILICITY; MOUTH MUCOSA; NERVE ENDING; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; TOPICAL ANESTHESIA; VISUAL ANALOG SCALE; ZETA POTENTIAL;

ADMINISTRATION, TOPICAL; ANESTHESIA, LOCAL; ANIMALS; BENZOCAINE; DRUG STABILITY; ESOPHAGUS; GELS; HEALTHY VOLUNTEERS; HUMANS; LIPOSOMES; MOUTH MUCOSA; PARTICLE SIZE; SWINE;

EID: 84873302842     PISSN: 08982104     EISSN: 15322394     Source Type: Journal    
DOI: 10.3109/08982104.2012.742536     Document Type: Article

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