Insulin-like growth factor (IGF) signaling requires αvβ3-IGF1- IGF type 1 receptor (IGF1R) ternary complex formation in anchorage independence, and the complex formation does not require IGF1R and Src activation

Journal of Biological Chemistry

Volumn 288, Issue 5, 2013, Pages 3059-3069

  Fujita, Masaaki ^a   Takada, Yoko K ^a   Takada, Yoshikazu ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEX FORMATIONS; INSULIN-LIKE GROWTH FACTOR; TERNARY COMPLEX; THERAPEUTIC TARGETS;

BIOCHEMISTRY; BIOLOGY;

ANCHORAGES (FOUNDATIONS);

MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN TYROSINE KINASE; SOMATOMEDIN; SOMATOMEDIN C RECEPTOR; VITRONECTIN RECEPTOR;

ANIMAL CELL; ARTICLE; CHO CELL; COMPLEX FORMATION; CONTROLLED STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION;

ANIMALS; CELL ADHESION; CHO CELLS; CONTACT INHIBITION; CRICETINAE; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HUMANS; INSULIN-LIKE GROWTH FACTOR I; INTEGRIN ALPHAVBETA3; MODELS, BIOLOGICAL; MULTIPROTEIN COMPLEXES; MUTATION; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECEPTOR, IGF TYPE 1; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES;

EID: 84873282225     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.412536     Document Type: Article

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