Hydroxylated PAHs alter the synthesis of androgens and estrogens in subcellular fractions of carp gonads

Science of the Total Environment

Volumn 447, Issue , 2013, Pages 152-159

  Fernandes, Denise ^a   Porte, Cinta ^a  

^a INSTITUTE OF ENVIRONMENTAL ASSESSMENT AND WATER RESEARCH   (Spain)

Author keywords

11 HSD2; C17,20 Lyase; Carp; CYP11 ; P450 aromatase; PAH metabolites

Indexed keywords

1-HYDROXYPYRENE; AROMATASE; C17,20-LYASE; CARP; CHRYSENE; CYPRINUS CARPIO; HYDROXYLATED METABOLITES; INHIBITORY EFFECT; SUBCELLULAR FRACTIONS;

ANTHRACENE; BIOCHEMISTRY; BIOMOLECULES; METABOLITES; NAPHTHALENE; PYRENE;

HYDROXYLATION;

1 HYDROXYCHRYSENE; 1 HYDROXYNAPHTHALENE; 1 HYDROXYPYRENE; 11BETA HYDROXYANDROSTENEDIONE; 11BETA HYDROXYSTEROID DEHYDROGENASE; 9 PHENANTHROL; ANDROGEN; ANDROSTENEDIONE; AROMATASE; CHRYSENE; CHRYSENE DERIVATIVE; CYTOCHROME P450 17; ESTROGEN; FISH PROTEIN; HYDROXYPROGESTERONE; NAPHTHALENE; NAPHTHALENE DERIVATIVE; PHENANTHRENE; PHENANTHRENE DERIVATIVE; POLYCYCLIC AROMATIC HYDROCARBON; PROTEIN CYP11BETA; PYRENE; UNCLASSIFIED DRUG;

ANDROGEN; CATALYSIS; CYPRINID; ESTROGENIC COMPOUND; NAPHTHALENE; PAH; PHENANTHRENE; PYRENE; STEROID;

ANDROGEN SYNTHESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CARP; CELL FRACTIONATION; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME INHIBITION; ESTROGEN SYNTHESIS; FEMALE; IC 50; IN VITRO STUDY; MALE; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; REPRODUCTIVE TOXICITY; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS;

11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 2; ANDROGENS; ANDROSTENES; ANIMALS; AROMATASE; CARPS; CHRYSENES; ESTROGENS; FEMALE; HYDROXYLATION; MALE; MITOCHONDRIA; OVARY; PHENANTHRENES; POLYCYCLIC HYDROCARBONS, AROMATIC; PYRENES; STEROID 17-ALPHA-HYDROXYLASE; SUBCELLULAR FRACTIONS; TESTIS; TOXICITY TESTS; WATER POLLUTANTS, CHEMICAL;

EID: 84873272653     PISSN: 00489697     EISSN: 18791026     Source Type: Journal    
DOI: 10.1016/j.scitotenv.2012.12.068     Document Type: Article

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