PIVL, a new serine protease inhibitor from Macrovipera lebetina transmediterranea venom, impairs motility of human glioblastoma cells

Matrix Biology

Volumn 32, Issue 1, 2013, Pages 52-62

  Morjen, Maram ^a   Kallech ziri, Olfa ^a   Bazaa, Amine ^a   Othman, Houcemeddine ^a   Mabrouk, Kamel ^b   Zouari kessentini, Raoudha ^a   Sanz, Libia ^c   Calvete, Juan José ^c   Srairi Abid, Najet ^a   El Ayeb, Mohamed ^a   Luis, José ^d,e   Marrakchi, Naziha ^a,f  

^a PASTEUR INSTITUTE OF TUNIS   (Tunisia)

^b AIX MARSEILLE UNIV   (France)

^c INSTITUTO DE BIOMEDICINA DE VALENCIA   (Spain)

^d AIX MARSEILLE UNIVERSITY   (France)

^e University of the Mediterranean Aix Marseille II   (France)

^f UNIVERSITY OF TUNIS EL MANAR   (Tunisia)

Author keywords

CDNA cloning; Cell motility; Integrin; Kunitz type serine protease inhibitor; Snake venom

Indexed keywords

ALPHAVBETA1 INTEGRIN; ALPHAVBETA5 INTEGRIN; ALPHAVBETA6 INTEGRIN; COMPLEMENTARY DNA; INTEGRIN; PEPTIDE; SERINE PROTEINASE INHIBITOR; SERINE PROTEINASE INHIBITOR PIVL; SNAKE VENOM; TRYPSIN; UNCLASSIFIED DRUG; VERY LATE ACTIVATION ANTIGEN 1; VITRONECTIN RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL ADHESION; CELL INVASION; CELL MIGRATION; CELL MOTILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA SEQUENCE; DRUG ISOLATION; DRUG PURIFICATION; DRUG STRUCTURE; ENZYME INHIBITION; GLIOMA CELL; HUMAN; HUMAN CELL; MACROVIPERA LEBETINA TRANSMEDITERRANEA; MOLECULAR CLONING; MOLECULAR MODEL; MOLECULAR WEIGHT; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SNAKE; TOXICITY;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CELL ADHESION; CELL LINE, TUMOR; CELL MOVEMENT; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CLONING, MOLECULAR; DNA PRIMERS; DNA, COMPLEMENTARY; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; INTEGRIN ALPHAVBETA3; LETHAL DOSE 50; MICROSCOPY, VIDEO; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PEPTIDES; PROTEIN CONFORMATION; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS, DNA; SERINE PROTEINASE INHIBITORS; TANDEM MASS SPECTROMETRY; TIME-LAPSE IMAGING; TUNISIA; VIPER VENOMS; VIPERIDAE;

MACROVIPERA LEBETINA;

EID: 84873250923     PISSN: 0945053X     EISSN: 15691802     Source Type: Journal    
DOI: 10.1016/j.matbio.2012.11.015     Document Type: Article

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