H. pylori infection is associated with DNA damage of Lgr5-positive epithelial stem cells in the stomach of patients with gastric cancer

Digestive Diseases and Sciences

Volumn 58, Issue 1, 2013, Pages 140-149

  Uehara, Takeshi ^a,b   Ma, Deqin ^a   Yao, Yuan ^a   Lynch, John P ^a   Morales, Knashawn ^a   Ziober, Amy ^a   Feldman, Michael ^a   Ota, Hiroyoshi ^b   Sepulveda, Antonia R ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b SHINSHU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

8OHdG; DNA damage; Gastric; Helicobacter pylori; Lgr5; Stem cells

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; BIOLOGICAL MARKER; G PROTEIN COUPLED RECEPTOR; LEUCINE RICH REPEAT CONTAINING G PROTEIN COUPLED RECEPTOR 5; UNCLASSIFIED DRUG;

ADULT; AGED; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CANCER PATIENT; CANCER RISK; CANCER STEM CELL; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE PREDISPOSITION; DNA DAMAGE; EPITHELIUM CELL; HELICOBACTER INFECTION; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMAGE ANALYSIS; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; SPECTROSCOPY; STOMACH ANTRUM; STOMACH CANCER; STOMACH EPITHELIUM; STOMACH MUCOSA;

DNA DAMAGE; EPITHELIAL CELLS; FLUORESCENT ANTIBODY TECHNIQUE; GASTRIC MUCOSA; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; IMMUNOHISTOCHEMISTRY; RECEPTORS, G-PROTEIN-COUPLED; STAINING AND LABELING; STEM CELLS; STOMACH NEOPLASMS;

EID: 84873198169     PISSN: 01632116     EISSN: 15732568     Source Type: Journal    
DOI: 10.1007/s10620-012-2360-8     Document Type: Article

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