Anticancer effects of O-desmethylangolensin are mediated through cell cycle arrest at the G2/M phase and mitochondrial-dependent apoptosis in Hep3B human hepatocellular carcinoma cells

International Journal of Molecular Medicine

Volumn 31, Issue 3, 2013, Pages 726-730

  Choi, Eun Jeong ^a   Lee, Jae In ^a   Kim, Gun Hee ^a  

^a Duksung Women's University   (South Korea)

Author keywords

Apoptosis; Cell cycle arrest; Daidzein; Hep3B cells; O desmethylangolensin

Indexed keywords

ANTINEOPLASTIC AGENT; CASPASE 3; CYCLIN A; CYCLIN B; CYCLIN DEPENDENT KINASE 1; CYTOCHROME C; LIPOCORTIN 5; O DESMETHYLANGOLENSIN; PROTEIN BAX; PROTEIN BCL 2; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; G2 PHASE CELL CYCLE CHECKPOINT; HUMAN; HUMAN CELL; IC 50; LIVER CELL CARCINOMA; M PHASE CELL CYCLE CHECKPOINT; MITOCHONDRION; PRIORITY JOURNAL; PROTEIN SECRETION; RECEPTOR DOWN REGULATION; RECEPTOR UPREGULATION;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CARCINOMA, HEPATOCELLULAR; CASPASE 3; CDC2 PROTEIN KINASE; CELL LINE, TUMOR; CELL PROLIFERATION; CYCLIN A; CYCLIN B; CYTOCHROMES C; G2 PHASE CELL CYCLE CHECKPOINTS; HUMANS; ISOFLAVONES; LIVER NEOPLASMS; MITOCHONDRIA; PHYTOESTROGENS; PROTO-ONCOGENE PROTEINS C-BCL-2;

EID: 84873185757     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.2013.1230     Document Type: Article

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