Effects of 7-O substitutions on estrogenic and anti-estrogenic activities of daidzein analogues in MCF-7 breast cancer cells

Journal of Medicinal Chemistry

Volumn 53, Issue 16, 2010, Pages 6153-6163

  Jiang, Quan ^a   Payton Stewart, Florastina ^a,b,c   Elliott, Steven ^b,c   Driver, Jennifer ^b   Rhodes, Lyndsay V ^b,c   Zhang, Qiang ^a   Zheng, Shilong ^d   Bhatnagar, Deepak ^e   Boue, Stephen M ^e   Collins Burow, Bridgette M ^b,c   Sridhar, Jayalakshmi ^a   Stevens, Cheryl ^a   McLachlan, John A ^b,c   Wiese, Thomas E ^a   Burow, Matthew E ^b,c   Wang, Guangdi ^a  

^a XAVIER UNIVERSITY OF LOUISIANA   (United States)

^b Tulane and Xavier Universities   (United States)

^c TULANE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d Tulane University School of Medicine ^*  (United States)

^e U S DEPARTMENT OF AGRICULTURE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 (4 HYDROXYPHENYL) 7 ISOBUTOXYCHROMEN 4 ONE; 3 (4 HYDROXYPHENYL) 7 ISOPROPOXYCHROMEN 4 ONE; 3 (4 HYDROXYPHENYL) 7 METHOXYCHROMEN 4 ONE; 3 (4 HYDROXYPHENYL) 7ETHOXYCHROMEN 4 ONE; 3 (4 HYDROXYPHENYL) 8,8 DIMETHYL 8H PYRANO[2,3 F]CHROMEN 4 ONE; 7 CYCLOPENTYLOXY 3 (4 HYDROXYPHENYL)CHROMEN 4 ONE; ANTIESTROGEN; DAIDZEIN; ESTROGEN RECEPTOR; FULVESTRANT; PROGESTERONE RECEPTOR; TAMOXIFEN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREAST CANCER; CANCER CELL; CANCER INHIBITION; CARCINOGENESIS; CELL PROLIFERATION; CONTROLLED STUDY; DRUG DESIGN; DRUG SYNTHESIS; ESTROGEN ACTIVITY; FEMALE; GENE EXPRESSION; MOLECULAR MODEL; MOUSE; NONHUMAN; STRUCTURE ACTIVITY RELATION; SUBSTITUTION REACTION; TUMOR XENOGRAFT;

ANIMALS; ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; CELL LINE, TUMOR; ESTRADIOL; ESTROGEN ANTAGONISTS; ESTROGEN RECEPTOR ALPHA; ESTROGENS; FEMALE; HUMANS; HYDROPHOBICITY; ISOFLAVONES; MICE; MICE, NUDE; MODELS, MOLECULAR; RECEPTORS, PROGESTERONE; RESPONSE ELEMENTS; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSCRIPTION, GENETIC; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 77955871456     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm100610w     Document Type: Article

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