-
1
-
-
4344576889
-
Acetaminophen-induced oxidant stress and cell injury in cultured mouse hepatocytes: protection by N-acetyl cysteine
-
BAJT ML, KNIGHT TR, LEMASTERS JJ, JAESCHKE H: Acetaminophen-induced oxidant stress and cell injury in cultured mouse hepatocytes: protection by N-acetyl cysteine. Toxicol Sci 80: 343-349, 2004.
-
(2004)
Toxicol Sci
, vol.80
, pp. 343-349
-
-
Bajt, M.L.1
Knight, T.R.2
Lemasters, J.J.3
Jaeschke, H.4
-
2
-
-
0017395968
-
A high-yield preparative method for isolation of rat liver mitochondria
-
BUSTAMANTE E, SOPER JW, PEDERSEN PL: A high-yield preparative method for isolation of rat liver mitochondria. Anal Biochem 80: 401-408, 1977.
-
(1977)
Anal Biochem
, vol.80
, pp. 401-408
-
-
Bustamante, E.1
Soper, J.W.2
Pedersen, P.L.3
-
3
-
-
0016808562
-
Purification and characterization of the flavoenzyme glutathione reductase from rat liver
-
CARLBERG I, MANNERVIK B: Purification and characterization of the flavoenzyme glutathione reductase from rat liver. J Biol Chem 250: 5475-5480, 1975.
-
(1975)
J Biol Chem
, vol.250
, pp. 5475-5480
-
-
Carlberg, I.1
Mannervik, B.2
-
4
-
-
0024044003
-
The spontaneous and enzymatic reaction of N-acetyl-p-benzoquinonimine with glutathione: a stopped-flow kinetic study
-
COLES B, WILSON I, WARDMAN P, HINSON JA, NELSON SD, KETTERER B: The spontaneous and enzymatic reaction of N-acetyl-p-benzoquinonimine with glutathione: a stopped-flow kinetic study. Arch Biochem Biophys 264: 253-260, 1988.
-
(1988)
Arch Biochem Biophys
, vol.264
, pp. 253-260
-
-
Coles, B.1
Wilson, I.2
Wardman, P.3
Hinson, J.A.4
Nelson, S.D.5
Ketterer, B.6
-
5
-
-
30144436108
-
Disruption of the glutathione transferase pi class genes
-
HENDERSON CJ, WOLF CR: Disruption of the glutathione transferase pi class genes. Methods Enzymol 401: 116-135, 2005.
-
(2005)
Methods Enzymol
, vol.401
, pp. 116-135
-
-
Henderson, C.J.1
Wolf, C.R.2
-
6
-
-
0033732323
-
Increased resistance to acetaminophen hepatotoxicity in mice lacking glutathione S-transferase Pi
-
HENDERSON CJ, WOLF CR, KITTERINGHAM N, POWELL H, OTTO D, PARK BK: Increased resistance to acetaminophen hepatotoxicity in mice lacking glutathione S-transferase Pi. Proc Natl Acad Sci U S A 97: 12741-12745, 2000.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 12741-12745
-
-
Henderson, C.J.1
Wolf, C.R.2
Kitteringham, N.3
Powell, H.4
Otto, D.5
Park, B.K.6
-
7
-
-
29544448331
-
Intracellular signaling mechanisms of acetaminophen-induced liver cell death
-
JAESCHKE H, BAJT ML: Intracellular signaling mechanisms of acetaminophen-induced liver cell death. Toxicol Sci 89: 31-41, 2006.
-
(2006)
Toxicol Sci
, vol.89
, pp. 31-41
-
-
Jaeschke, H.1
Bajt, M.L.2
-
8
-
-
79954615800
-
Current issues with acetaminophen hepatotoxicity - a clinically relevant model to test the efficacy of natural products
-
JAESCHKE H, MCGILL MR, WILLIAMS CD, RAMACHANDRAN A: Current issues with acetaminophen hepatotoxicity - a clinically relevant model to test the efficacy of natural products. Life Sci 88: 737-745, 2011.
-
(2011)
Life Sci
, vol.88
, pp. 737-745
-
-
Jaeschke, H.1
Mcgill, M.R.2
Williams, C.D.3
Ramachandran, A.4
-
10
-
-
7044226521
-
Mitochondrial permeability transition in acetaminophen-induced necrosis and apoptosis of cultured mouse hepatocytes
-
KON K, KIM JS, JAESCHKE H, LEMASTERS JJ: Mitochondrial permeability transition in acetaminophen-induced necrosis and apoptosis of cultured mouse hepatocytes. Hepatology 40: 1170-1179, 2004.
-
(2004)
Hepatology
, vol.40
, pp. 1170-1179
-
-
Kon, K.1
Kim, J.S.2
Jaeschke, H.3
Lemasters, J.J.4
-
11
-
-
3042738919
-
Acetaminophen and the US. Acute Liver Failure Study Group: lowering the risks of hepatic failure
-
LEE WM: Acetaminophen and the U.S. Acute Liver Failure Study Group: lowering the risks of hepatic failure. Hepatology 40: 6-9, 2004.
-
(2004)
Hepatology
, vol.40
, pp. 6-9
-
-
Lee, W.M.1
-
12
-
-
0033067354
-
Regulation of hepatic glutathione synthesis: current concepts and controversies
-
LU SC: Regulation of hepatic glutathione synthesis: current concepts and controversies. FASEB J 13: 1169-1183, 1999.
-
(1999)
FASEB J
, vol.13
, pp. 1169-1183
-
-
Lu, S.C.1
-
13
-
-
34250731278
-
Development and evaluation of an electrochemical method for studying reactive phase-I metabolites: correlation to in vitro drug metabolism
-
MADSEN KG, OLSEN J, SKONBERG C, HANSEN SH, JURVA U: Development and evaluation of an electrochemical method for studying reactive phase-I metabolites: correlation to in vitro drug metabolism. Chem Res Toxicol 20: 821-831, 2007.
-
(2007)
Chem Res Toxicol
, vol.20
, pp. 821-831
-
-
Madsen, K.G.1
Olsen, J.2
Skonberg, C.3
Hansen, S.H.4
Jurva, U.5
-
14
-
-
0018621529
-
Evidence for the involvement of N-acetyl-p-quinoneimine in acetaminophen metabolism
-
MINER DJ, KISSINGER PT: Evidence for the involvement of N-acetyl-p-quinoneimine in acetaminophen metabolism. Biochem Pharmacol 28: 3285-3290, 1979.
-
(1979)
Biochem Pharmacol
, vol.28
, pp. 3285-3290
-
-
Miner, D.J.1
Kissinger, P.T.2
-
15
-
-
0015748302
-
Acetaminophen-induced hepatic necrosis I. Role of drug metabolism
-
MITCHELL JR, JOLLOW DJ, POTTER WZ, DAVIS DC, GILLETTE JR, BRODIE BB: Acetaminophen-induced hepatic necrosis. I. Role of drug metabolism. J Pharmacol Exp Ther 187: 185-194, 1973a.
-
(1973)
J Pharmacol Exp Ther
, vol.187
, pp. 185-194
-
-
Mitchell, J.R.1
Jollow, D.J.2
Potter, W.Z.3
Davis, D.C.4
Gillette, J.R.5
Brodie, B.B.6
-
16
-
-
0015733053
-
Acetaminophen-induced hepatic necrosis IV. Protective role of glutathione
-
MITCHELL JR, JOLLOW DJ, POTTER WZ, GILLETTE JR, BRODIE BB: Acetaminophen-induced hepatic necrosis. IV. Protective role of glutathione. J Pharmacol Exp Ther 187: 211-217, 1973b.
-
(1973)
J Pharmacol Exp Ther
, vol.187
, pp. 211-217
-
-
Mitchell, J.R.1
Jollow, D.J.2
Potter, W.Z.3
Gillette, J.R.4
Brodie, B.B.5
-
17
-
-
58249093939
-
How mitochondria produce reactive oxygen species
-
MURPHY MP: How mitochondria produce reactive oxygen species. Biochem J 417: 1-13, 2009.
-
(2009)
Biochem J
, vol.417
, pp. 1-13
-
-
Murphy, M.P.1
-
18
-
-
0023103693
-
Mechanisms of acetaminophen oxidation to N-acetyl-P-benzoquinone imine by horseradish peroxidase and cytochrome P-450
-
POTTER DW, HINSON JA: Mechanisms of acetaminophen oxidation to N-acetyl-P-benzoquinone imine by horseradish peroxidase and cytochrome P-450. J Biol Chem 262: 966-973, 1987.
-
(1987)
J Biol Chem
, vol.262
, pp. 966-973
-
-
Potter, D.W.1
Hinson, J.A.2
-
19
-
-
77953924015
-
Glutathione reductase is inhibited by acetaminophen-glutathione conjugate in vitro
-
ROUŠAR T, PAŘÍK P, KUČERA O, BARTOŠ M, ČERVINKOVÁ Z: Glutathione reductase is inhibited by acetaminophen-glutathione conjugate in vitro. Physiol Res 59: 225-232, 2010.
-
(2010)
Physiol Res
, vol.59
, pp. 225-232
-
-
Roušar, T.1
Pařík, P.2
Kučera, O.3
Bartoš, M.4
Červinková, Z.5
-
20
-
-
0017360297
-
Rat liver glutathione: possible role as a reservoir of cysteine
-
TATEISHI N, HIGASHI T, NARUSE A, NAKASHIMA K, SHIOZAKI H: Rat liver glutathione: possible role as a reservoir of cysteine. J Nutr 107: 51-60, 1977.
-
(1977)
J Nutr
, vol.107
, pp. 51-60
-
-
Tateishi, N.1
Higashi, T.2
Naruse, A.3
Nakashima, K.4
Shiozaki, H.5
-
21
-
-
0034834292
-
Analysis of the glutathione conjugate of paracetamol in human liver microsomal fraction by liquid chromatography mass spectrometry
-
THATCHER NJ, MURRAY S: Analysis of the glutathione conjugate of paracetamol in human liver microsomal fraction by liquid chromatography mass spectrometry. Biomed Chromatogr 15: 374-378, 2001.
-
(2001)
Biomed Chromatogr
, vol.15
, pp. 374-378
-
-
Thatcher, N.J.1
Murray, S.2
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