메뉴 건너뛰기




Volumn 38, Issue 1, 2013, Pages 103-114

Differential mRNA expression and the uptake of methotrexate in primary MAEC and MLF cells: Involvement of the Abc and Slco/Oatp transporters in alveolar epithelial cell toxicity

Author keywords

Drug transporters; MAEC; Methotrexate; MLF; Pulmonary toxicity

Indexed keywords

ABC TRANSPORTER; BREAST CANCER RESISTANCE PROTEIN; METHOTREXATE; MULTIDRUG RESISTANCE PROTEIN 1; MULTIDRUG RESISTANCE PROTEIN 3; MULTIDRUG RESISTANCE PROTEIN 4; MULTIDRUG RESISTANCE PROTEIN 5; ORGANIC ANION TRANSPORTER; ORGANIC ANION TRANSPORTER 2; ORGANIC ANION TRANSPORTER 3; ORGANIC ANION TRANSPORTER 4; REDUCED FOLATE CARRIER; VERLUKAST;

EID: 84873111875     PISSN: 03881350     EISSN: 18803989     Source Type: Journal    
DOI: 10.2131/jts.38.103     Document Type: Article
Times cited : (10)

References (29)
  • 1
    • 33846681607 scopus 로고    scopus 로고
    • Multidrug resistance-associated proteins 3, 4, and 5
    • Borst, P., de Wolf, C. and van de Wetering, K. (2007): Multidrug resistance-associated proteins 3, 4, and 5. Pflugers. Arch., 453, 661-673.
    • (2007) Pflugers. Arch , vol.453 , pp. 661-673
    • Borst, P.1    de Wolf, C.2    van de Wetering, K.3
  • 3
    • 0023143528 scopus 로고
    • Pulmonary disease during the treatment of rheumatoid arthritis with low dose pulse methotrexate
    • Carson, C.W., Cannon, G.W., Egger, M.J., Ward, J.R. and Clegg, D.O. (1987): Pulmonary disease during the treatment of rheumatoid arthritis with low dose pulse methotrexate. Semin. Arthritis Rheum., 16, 186-195.
    • (1987) Semin. Arthritis Rheum , vol.16 , pp. 186-195
    • Carson, C.W.1    Cannon, G.W.2    Egger, M.J.3    Ward, J.R.4    Clegg, D.O.5
  • 4
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    • Chomczynski, P. and Sacchi, N. (1987): Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem., 162, 156-159.
    • (1987) Anal. Biochem , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 5
    • 34247236764 scopus 로고    scopus 로고
    • Transport of the dipeptidyl peptidase-4 inhibitor sitagliptin by human organic anion transporter 3, organic anion transporting polypeptide 4C1, and multidrug resistance P-glycoprotein
    • Chu, X.Y., Bleasby, K., Yabut, J., Cai, X., Chan, G.H., Hafey, M.J., Xu, S., Bergman, A.J., Braun, M.P., Dean, D.C. and Evers, R. (2007): Transport of the dipeptidyl peptidase-4 inhibitor sitagliptin by human organic anion transporter 3, organic anion transporting polypeptide 4C1, and multidrug resistance P-glycoprotein. J. Pharmacol. Exp. Ther., 321, 673-683.
    • (2007) J. Pharmacol. Exp. Ther , vol.321 , pp. 673-683
    • Chu, X.Y.1    Bleasby, K.2    Yabut, J.3    Cai, X.4    Chan, G.H.5    Hafey, M.J.6    Xu, S.7    Bergman, A.J.8    Braun, M.P.9    Dean, D.C.10    Evers, R.11
  • 6
    • 0027982786 scopus 로고
    • A novel cDNA restores reduced folate carrier activity and methotrexate sensitivity to transport deficient cells
    • Dixon, K.H., Lanpher, B.C., Chiu, J., Kelley, K. and Cowan, K.H. (1994): A novel cDNA restores reduced folate carrier activity and methotrexate sensitivity to transport deficient cells. J. Biol. Chem., 269, 17-20.
    • (1994) J. Biol. Chem , vol.269 , pp. 17-20
    • Dixon, K.H.1    Lanpher, B.C.2    Chiu, J.3    Kelley, K.4    Cowan, K.H.5
  • 8
    • 0033964302 scopus 로고    scopus 로고
    • Methotrexate pneumonitis: Review of the literature and histopathological findings in nine patients
    • Imokawa, S., Colby, T.V., Leslie, K.O. and Helmers, R.A. (2000): Methotrexate pneumonitis: review of the literature and histopathological findings in nine patients. Eur. Respir. J., 15, 373-381.
    • (2000) Eur. Respir. J , vol.15 , pp. 373-381
    • Imokawa, S.1    Colby, T.V.2    Leslie, K.O.3    Helmers, R.A.4
  • 9
    • 84862670760 scopus 로고    scopus 로고
    • Optimal use of non-biologic therapy in the treatment of rheumatoid arthritis
    • Jacobs, W.G. (2012): Optimal use of non-biologic therapy in the treatment of rheumatoid arthritis. Rheumatology, 51, iv3-iv8.
    • (2012) Rheumatology , vol.51
    • Jacobs, W.G.1
  • 10
    • 77949398878 scopus 로고    scopus 로고
    • Xenobiotic, bile acid and cholesterol transporters: Function and regulation
    • Klaassenn, C.D. and Aleksunes, L.M. (2010): Xenobiotic, bile acid and cholesterol transporters: function and regulation. Pharmacol. Rev., 62, 1-96.
    • (2010) Pharmacol. Rev , vol.62 , pp. 1-96
    • Klaassenn, C.D.1    Aleksunes, L.M.2
  • 12
  • 13
    • 78649656801 scopus 로고    scopus 로고
    • Uptake transporters of the human OATP family: Molecular characteristics, substrates, their role in drug-drug interactions, and functional consequences of polymorphisms
    • Konig, J. (2011): Uptake transporters of the human OATP family: molecular characteristics, substrates, their role in drug-drug interactions, and functional consequences of polymorphisms. Handb. Exp. Pharmacol., 201, 1-28.
    • (2011) Handb. Exp. Pharmacol , vol.201 , pp. 1-28
    • Konig, J.1
  • 14
    • 0022547880 scopus 로고
    • Methotrexate metabolism analysis in blood and liver of rheumatoid arthritis patients. Association with hepatic folate deficiency and formation of polyglutamates
    • Kremer, J.M., Galivan, J., Streckfuss, A. and Kamen, B. (1986): Methotrexate metabolism analysis in blood and liver of rheumatoid arthritis patients. Association with hepatic folate deficiency and formation of polyglutamates. Arthritis Rheum., 29, 832-835.
    • (1986) Arthritis Rheum , vol.29 , pp. 832-835
    • Kremer, J.M.1    Galivan, J.2    Streckfuss, A.3    Kamen, B.4
  • 17
    • 22344432207 scopus 로고    scopus 로고
    • Tissue distribution and hepatic and renal ontogeny of the multidrug resistance-associated protein (Mrp) family in mice
    • Maher, J.M., Slitt, A.L., Cherrington, N.J., Cheng, X. and Klaassen, C.D. (2005): Tissue distribution and hepatic and renal ontogeny of the multidrug resistance-associated protein (Mrp) family in mice. Drug Metab. Dispos., 33, 947-955.
    • (2005) Drug Metab. Dispos , vol.33 , pp. 947-955
    • Maher, J.M.1    Slitt, A.L.2    Cherrington, N.J.3    Cheng, X.4    Klaassen, C.D.5
  • 19
    • 67650084777 scopus 로고    scopus 로고
    • Identification of novel specific and general inhibitors of the three major human ATP-binding cassette transporters P-gp, BCRP and MRP2 among registered drugs
    • Matsson, P., Pedersen, J.M., Norinder, U., Bergstrom, C.A. and Artursson, P. (2009): Identification of novel specific and general inhibitors of the three major human ATP-binding cassette transporters P-gp, BCRP and MRP2 among registered drugs. Pharm. Res., 26, 1816-1831.
    • (2009) Pharm. Res. , vol.26 , pp. 1816-1831
    • Matsson, P.1    Pedersen, J.M.2    Norinder, U.3    Bergstrom, C.A.4    Artursson, P.5
  • 22
    • 0029786681 scopus 로고    scopus 로고
    • Cloning and functional characterization of a novel rat organic anion transporter mediating basolateral uptake of methotrexate in the kidney
    • Saito, H., Masuda, S. and Inui, K. (1996): Cloning and functional characterization of a novel rat organic anion transporter mediating basolateral uptake of methotrexate in the kidney. J. Biol. Chem., 271, 20719-20725.
    • (1996) J. Biol. Chem , vol.271 , pp. 20719-20725
    • Saito, H.1    Masuda, S.2    Inui, K.3
  • 23
    • 65249089205 scopus 로고    scopus 로고
    • Contribution of organic anion transporting polypeptide OATP2B1 to amiodarone accumulation in lung epithelial cells
    • Seki, S., Kobayashi, M., Itagaki, S., Hirano, T. and Iseki, K. (2009): Contribution of organic anion transporting polypeptide OATP2B1 to amiodarone accumulation in lung epithelial cells. Biochim. Biophys. Acta., 1788, 911-917.
    • (2009) Biochim. Biophys. Acta , vol.1788 , pp. 911-917
    • Seki, S.1    Kobayashi, M.2    Itagaki, S.3    Hirano, T.4    Iseki, K.5
  • 24
    • 0030855487 scopus 로고    scopus 로고
    • Expression cloning and characterization of a novel multispecific organic anion transporter
    • Sekine, T., Watanabe, N., Hosoyamada, M., Kanai, Y. and Endou, H. (1997): Expression cloning and characterization of a novel multispecific organic anion transporter. J. Biol. Chem., 272, 18526-18529.
    • (1997) J. Biol. Chem , vol.272 , pp. 18526-18529
    • Sekine, T.1    Watanabe, N.2    Hosoyamada, M.3    Kanai, Y.4    Endou, H.5
  • 25
    • 0022376725 scopus 로고
    • Pneumonitis complicating low-dose methotrexate therapy in rheumatoid arthritis
    • St. Clair, E.W Rice, J.R. and Snyderman, R. (1985): Pneumonitis complicating low-dose methotrexate therapy in rheumatoid arthritis. Arch. Intern. Med., 145, 2035-2038.
    • (1985) Arch. Intern. Med , vol.145 , pp. 2035-2038
    • Clair, S.1    Rice, E.W.2    Snyderman, R.3
  • 26
    • 84856070846 scopus 로고    scopus 로고
    • Substrate- and pH-specific antifolate transport mediated by organic anion-transporting polypeptide 2B1 (OATP2B1- SLCO2B1)
    • Visentin, M., Chang, M.H., Romero, M.F., Zhao, R. and Goldman, I.D. (2012): Substrate- and pH-specific antifolate transport mediated by organic anion-transporting polypeptide 2B1 (OATP2B1- SLCO2B1). Mol. Pharmacol., 81, 134-142.
    • (2012) Mol. Pharmacol , vol.81 , pp. 134-142
    • Visentin, M.1    Chang, M.H.2    Romero, M.F.3    Zhao, R.4    Goldman, I.D.5
  • 27
    • 0035476729 scopus 로고    scopus 로고
    • Transport of methotrexate (MTX) and folates by multidrug resistance protein (MRP) 3 and MRP1: Effect of polyglutamylation on MTX transport
    • Zeng, H., Chen, Z.S., Belinsky, M.G., Rea, P.A. and Kruh, G.D. (2001): Transport of methotrexate (MTX) and folates by multidrug resistance protein (MRP) 3 and MRP1: effect of polyglutamylation on MTX transport. Cancer Res., 61, 7225-7232.
    • (2001) Cancer Res , vol.61 , pp. 7225-7232
    • Zeng, H.1    Chen, Z.S.2    Belinsky, M.G.3    Rea, P.A.4    Kruh, G.D.5
  • 28
    • 70349110758 scopus 로고    scopus 로고
    • Role of multidrug resistance associated proteins in drug development
    • Zhou, S.F. (2008): Role of multidrug resistance associated proteins in drug development. Drug Discov. Ther., 2, 305-332.
    • (2008) Drug Discov. Ther , vol.2 , pp. 305-332
    • Zhou, S.F.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.