The instant blood-mediated inflammatory reaction characterized in hepatocyte transplantation

Transplantation

Volumn 91, Issue 6, 2011, Pages 632-638

  Gustafson, Elisabet K ^a   Elgue, Graciela ^b   Hughes, Robin D ^c   Mitry, Ragai R ^c   Sanchez, Javier ^b   Haglund, Ulf ^a   Meurling, Staffan ^a   Dhawan, Anil ^c   Korsgren, Olle ^b   Nilsson, Bo ^b,d  

^a UPPSALA UNIVERSITY HOSPITAL   (Sweden)

^b UPPSALA UNIVERSITY   (Sweden)

^c KING S COLLEGE HOSPITAL   (United Kingdom)

^d UPPSALA UNIVERSITY   (Sweden)

Author keywords

Cell transplantation; Engraftment; IBMIR; Innate immunity; Islet transplantation

Indexed keywords

DEXTRAN SULFATE;

ARTICLE; BLOOD CLOTTING; BLOOD GROUP ABO SYSTEM; CELL FUNCTION; CELL LOSS; CONTROLLED STUDY; GRANULOCYTE; HEPATOCYTE TRANSPLANTATION; HUMAN; HUMAN CELL; IN VIVO STUDY; INFLAMMATION; INNATE IMMUNITY; INSTANT BLOOD MEDIATED INFLAMMATORY REACTION; LIVER CELL; LYMPHOCYTE; MONOCYTE; PORTAL VEIN BLOOD FLOW; PRIORITY JOURNAL; THROMBOCYTE;

ABO BLOOD-GROUP SYSTEM; BLOOD COAGULATION; CELLS, CULTURED; DEXTRAN SULFATE; HEPATOCYTES; HUMANS; IMMUNOHISTOCHEMISTRY; INFLAMMATION; POSTOPERATIVE COMPLICATIONS; THROMBOPLASTIN;

EID: 79952753132     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/TP.0b013e31820ae459     Document Type: Article

References (42)

1. Matas AJ, Sutherland DE, Steffes MW, et al. Hepatocellular transplantation for metabolic deficiencies: Decrease of plasms bilirubin in Gunn rats. Science 1976; 192: 892.
2. Groth CG, Arborgh B, Bjorken C, et al. Correction of hyperbilirubinemia in the glucuronyltransferase-deficient rat by intraportal hepatocyte transplantation. Transplant Proc 1977; 9: 313.
3. Demetriou AA, Reisner A, Sanchez J, et al. Transplantation of microcarrier-attached hepatocytes into 90% partially hepatectomized rats. Hepatology 1988; 8: 1006.
4. Kobayashi N, Ito M, Nakamura J, et al. Hepatocyte transplantation in rats with decompensated cirrhosis. Hepatology 2000; 31: 851.
5. Fox IJ, Chowdhury JR, Kaufman SS, et al. Treatment of the Crigler-Najjar syndrome type I with hepatocyte transplantation. N Engl J Med 1998; 338: 1422.
6. Horslen SP, McCowan TC, Goertzen TC, et al. Isolated hepatocyte transplantation in an infant with a severe urea cycle disorder. Pediatrics 2003; 111: 1262.
7. Strom SC, Fisher RA, Thompson MT, et al. Hepatocyte transplantation as a bridge to orthotopic liver transplantation in terminal liver failure. Transplantation 1997; 63: 559.
8. Strom SC, Chowdhury JR, Fox IJ. Hepatocyte transplantation for the treatment of human disease. Semin Liver Dis 1999; 19: 39.
9. Muraca M, Gerunda G, Neri D, et al. Hepatocyte transplantation as a treatment for glycogen storage disease type 1a. Lancet 2002; 359: 317.
10. Mito M, Kusano M, Kawaura Y. Hepatocyte transplantation in man. Transplant Proc 1992; 24: 3052.
11. Fox IJ, Chowdhury JR. Hepatocyte transplantation. Am J Transplant 2004; 4(suppl 6): 7.
12. Strom SC, Fisher RA, Rubinstein WS, et al. Transplantation of human hepatocytes. Transplant Proc 1997; 29: 2103.
13. Rajvanshi P, Kerr A, Bhargava KK, et al. Studies of liver repopulation using the dipeptidyl peptidase IV-deficient rat and other rodent recipients: Cell size and structure relationships regulate capacity for increased transplanted hepatocyte mass in the liver lobule. Hepatology 1996; 23: 482.
14. Slehria S, Rajvanshi P, Ito Y, et al. Hepatic sinusoidal vasodilators improve transplanted cell engraftment and ameliorate microcirculatory perturbations in the liver. Hepatology 2002; 35: 1320.
15. Gupta S, Rajvanshi P, Sokhi R, et al. Entry and integration of transplanted hepatocytes in rat liver plates occur by disruption of hepatic sinusoidal endothelium. Hepatology 1999; 29: 509.
16. Malhi H, Annamaneni P, Slehria S, et al. Cyclophosphamide disrupts hepatic sinusoidal endothelium and improves transplanted cell engraftment in rat liver. Hepatology 2002; 36: 112.
17. Joseph B, Malhi H, Bhargava KK, et al. Kupffer cells participate in early clearance of syngeneic hepatocytes transplanted in the rat liver. Gastroenterology 2002; 123: 1677.
18. Bennet W, Sundberg B, Groth CG, et al. Incompatibility between human blood and isolated islets of Langerhans: A finding with implications for clinical intraportal islet transplantation? Diabetes 1999; 48: 1907.
19. Moberg L, Johansson H, Lukinius A, et al. Production of tissue factor by pancreatic islet cells as a trigger of detrimental thrombotic reactions in clinical islet transplantation. Lancet 2002; 360: 2039.
20. Johansson H, Lukinius A, Moberg L, et al. Tissue factor produced by the endocrine cells of the islets of Langerhans is associated with a negative outcome of clinical islet transplantation. Diabetes 2005; 54: 1755.
21. Gong J, Larsson R, Ekdahl KN, et al. Tubing loops as a model for cardiopulmonary bypass circuits: Both the biomaterial and the bloodgas phase interfaces induce complement activation in an in vitro model. J Clin Immunol 1996; 16: 222.
22. Larsson R, Elgue G, Larsson A, et al. Inhibition of complement activation by soluble recombinant CR1 under conditions resembling those in a cardiopulmonary circuit: Reduced up-regulation of CD11b and complete abrogation of binding of PMNs to the biomaterial surface. Immunopharmacology 1997; 38: 119.
23. Puppi J, Tan N, Mitry RR, et al. Hepatocyte transplantation followed by auxiliary liver transplantation -A novel treatment for ornithine transcarbamylase deficiency. Am J Transplant 2008; 8: 452.
24. Ozmen L, Ekdahl KN, Elgue G, et al. Inhibition of thrombin abrogates the instant blood-mediated inflammatory reaction triggered by isolated human islets: Possible application of the thrombin inhibitor melagatran in clinical islet transplantation. Diabetes 2002; 51: 1779.
25. Hamad OA, Ekdahl KN, Nilsson PH, et al. Complement activation triggered by chondroitin sulfate released by thrombin receptor-activated platelets. J Thromb Haemost 2008; 6: 1413.
26. Hjortoe G, Sorensen BB, Petersen LC, et al. Factor VIIa binding and internalization in hepatocytes. J Thromb Haemost 2005; 3: 2264.
27. Dhawan A, Mitry RR, Hughes RD, et al. Hepatocyte transplantation for inherited factor VII deficiency. Transplantation 2004; 78: 1812.
28. Stephenne X, Vosters O, Najimi M, et al. Tissue factor-dependent procoagulant activity of isolated human hepatocytes: Relevance to liver cell transplantation. Liver Transpl 2007; 13: 599.
29. Willingham AK, Matschiner JT. The activation of factor X by hepatocyte plasma membranes. Cell Mol Biol 1989; 35: 421.
30. Rosenthal RJ, Chen SC, Hewitt W, et al. Techniques for intrasplenic hepatocyte transplantation in the large animal model. Surg Endosc 1996; 10: 1075.
31. Quaglia A, Lehec SC, Hughes RD, et al. Liver after hepatocyte transplantation for liver-based metabolic disorders in children. Cell Transplant 2008; 17: 1403.
32. Krohn N, Kapoor S, Enami Y, et al. Hepatocyte transplantation-induced liver inflammation is driven by cytokines-chemokines associated with neutrophils and Kupffer cells. Gastroenterology 2009; 136: 1806.
33. Johansson H, Goto M, Dufrane D, et al. Low molecular weight dextran sulfate: A strong candidate drug to block IBMIR in clinical islet transplantation. Am J Transplant 2006; 6: 305.
34. Goto M, Johansson H, Maeda A, et al. Low molecular weight dextran sulfate prevents the instant blood-mediated inflammatory reaction induced by adult porcine islets. Transplantation 2004; 77: 741.
35. Schmidt P, Magnusson C, Lundgren T, et al. Low molecular weight dextran sulfate is well tolerated in humans and increases endogenous expression of islet protective hepatocyte growth factor. Transplantation 2008; 86: 1523.
36. Leja J, Dzojic H, Gustafson E, et al. A novel chromogranin-A promoterdriven oncolytic adenovirus for midgut carcinoid therapy. Clin Cancer Res 2007; 13: 2455.
37. Strom SC, Pisarov LA, Dorko K, et al. Use of human hepatocytes to study P450 gene induction. Methods Enzymol 1996; 272: 388.
38. Kreamer BL, Staecker JL, Sawada N, et al. Use of a low-speed, isodensity percoll centrifugation method to increase the viability of isolated rat hepatocyte preparations. In Vitro Cell Dev Biol 1986; 22: 201.
39. Sanchez J, Elgue G, Riesenfeld J, et al. Studies of adsorption, activation, and inhibition of factor XII on immobilized heparin. Thromb Res 1998; 89: 41.
40. Nilsson Ekdahl K, Nilsson B, Pekna M, et al. Generation of iC3 at the interface between blood and gas. Scand J Immunol 1992; 35: 85.
41. Vermehren D, Sumitran-Holgersson S. Isolation of precursor endothelial cells from peripheral blood for donor-specific crossmatching before organ transplantation. Transplantation 2002; 74: 1479.
42. Nava S, Westgren M, Jaksch M, et al. Characterization of cells in the developing human liver. Differentiation 2005; 73: 249.