Kinetic and chemical mechanisms of the fabG-encoded Streptococcus pneumoniae β-ketoacyl-ACP reductase

Biochemistry

Volumn 44, Issue 50, 2005, Pages 16753-16765

  Patel, Mehul P ^a   Liu, Wu Schyong ^a   West, Joshua ^a   Tew, David ^a   Meek, Thomas D ^a   Thrall, Sara H ^a  

^a GLAXOSMITHKLINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIA; BIOSYNTHESIS; CATALYSIS; DEUTERIUM; ENZYMES; FATTY ACIDS; ISOTOPES; PH EFFECTS;

Β-KETOACYL-ACYL CARRIER PROTEIN REDUCTASE (KACPR); CHEMICAL MECHANISMS; PRODUCT INHIBITION; STREPTOCOCCUS PNEUMONIAE;

ENZYME KINETICS;

3 OXOACYL ACYL CARRIER PROTEIN SYNTHASE; ACETYL COENZYME A ACETYLTRANSFERASE; ACYL CARRIER PROTEIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE;

ARTICLE; BACTERIAL GENOME; CATALYSIS; CHEMICAL REACTION KINETICS; COMPLEX FORMATION; ENZYME ANALYSIS; ENZYME SUBSTRATE; FATTY ACID SYNTHESIS; GENE IDENTIFICATION; MULTIDRUG RESISTANCE; NONHUMAN; PRIORITY JOURNAL; PROTON TRANSPORT; RESPIRATORY TRACT INFECTION; SCREENING; STREPTOCOCCUS PNEUMONIAE;

ALCOHOL OXIDOREDUCTASES; BASE SEQUENCE; CATALYSIS; CLONING, MOLECULAR; DEUTERIUM; DNA PRIMERS; HYDROGEN-ION CONCENTRATION; KINETICS; STREPTOCOCCUS PNEUMONIAE;

BACTERIA (MICROORGANISMS); STREPTOCOCCUS PNEUMONIAE;

EID: 29244441171     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi050947j     Document Type: Article

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