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Volumn 22, Issue 1, 2013, Pages 147-158

The combined expression of Pdx1 and MafA with either Ngn3 or NeuroD improves the differentiation efficiency of mouse embryonic stem cells into insulin-producing cells

Author keywords

Differentiation efficiency; Embryonic stem cells; Insulin secreting cells; Transcription factors

Indexed keywords

ADENOVIRUS VECTOR; C PEPTIDE; GLUCOSE; GREEN FLUORESCENT PROTEIN; INSULIN; NEUROGENIC DIFFERENTIATION FACTOR; NEUROGENIN 3; TRANSCRIPTION FACTOR MAFA; TRANSCRIPTION FACTOR PDX 1;

EID: 84873041547     PISSN: 09636897     EISSN: None     Source Type: Journal    
DOI: 10.3727/096368912X653057     Document Type: Article
Times cited : (34)

References (42)
  • 1
    • 0036323269 scopus 로고    scopus 로고
    • Insulinotropic hormone glucagon-like peptide-1 differentiation of human pancreatic islet-derived progenitor cells into insulin-producing cells
    • Abraham, E. J.; Leech, C. A.; Lin, J. C.; Zulewski, H.; Habener, J. F. Insulinotropic hormone glucagon-like peptide-1 differentiation of human pancreatic islet-derived progenitor cells into insulin-producing cells. Endocrinology 143(8):3152-3161; 2002.
    • (2002) Endocrinology , vol.143 , Issue.8 , pp. 3152-3161
    • Abraham, E.J.1    Leech, C.A.2    Lin, J.C.3    Zulewski, H.4    Habener, J.F.5
  • 2
    • 22444443484 scopus 로고    scopus 로고
    • Synergistic activation of the insulin gene promoter by the beta-cell ranscription factors MafA, Beta2, and Pdx1
    • Aramata, S.; Han, S. I.; Yasuda, K.; Kataoka, K. Synergistic activation of the insulin gene promoter by the beta-cell ranscription factors MafA, Beta2, and Pdx1. Biochim. Biophys. Acta 1730(1):41-46; 2005.
    • (2005) Biochim. Biophys. Acta , vol.1730 , Issue.1 , pp. 41-46
    • Aramata, S.1    Han, S.I.2    Yasuda, K.3    Kataoka, K.4
  • 3
    • 62549083921 scopus 로고    scopus 로고
    • Biphasic induction of Pdx1 in mouse and human embryonic stem cells can mimic development of pancreatic beta-cells
    • Bernardo, A. S.; Cho, C. H.; Mason, S.; Docherty, H. M.; Pedersen, R. A.; Vallier, L.; Docherty, K. Biphasic induction of Pdx1 in mouse and human embryonic stem cells can mimic development of pancreatic beta-cells. Stem Cells 27(2):341-351; 2009.
    • (2009) Stem Cells , vol.27 , Issue.2 , pp. 341-351
    • Bernardo, A.S.1    Cho, C.H.2    Mason, S.3    Docherty, H.M.4    Pedersen, R.A.5    Vallier, L.6    Docherty, K.7
  • 4
    • 0037417958 scopus 로고    scopus 로고
    • Expression of Pax4 in embryonic stem cells promotes differentiation of nestin-positive progenitor and insulin-producing cells
    • Blyszczuk, P.; Czyz, J.; Kania, G.; Wagner, M.; Roll, U.; St-Onge, L.; Wobus, A. M. Expression of Pax4 in embryonic stem cells promotes differentiation of nestin-positive progenitor and insulin-producing cells. Proc. Natl. Acad. Sci. USA 100(3):998-1003; 2003.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , Issue.3 , pp. 998-1003
    • Blyszczuk, P.1    Czyz, J.2    Kania, G.3    Wagner, M.4    Roll, U.5    St-Onge, L.6    Wobus, A.M.7
  • 5
    • 33845270456 scopus 로고    scopus 로고
    • Transcription factors regulating beta-cell function
    • Cerf, M. E. Transcription factors regulating beta-cell function. Eur. J. Endocrinol. 155(5):671-679; 2006.
    • (2006) Eur. J. Endocrinol. , vol.155 , Issue.5 , pp. 671-679
    • Cerf, M.E.1
  • 7
    • 78651501561 scopus 로고    scopus 로고
    • Stem cell research in cell transplantation: Sources, geopolitical influence, and transplantation
    • Eve, D. J.; Fillmore, R. W.; Borlongan, C. V.; Sanberg, P. R. Stem cell research in cell transplantation: Sources, geopolitical influence, and transplantation. Cell Transplant 19(11):1493-1509; 2010.
    • (2010) Cell Transplant , vol.19 , Issue.11 , pp. 1493-1509
    • Eve, D.J.1    Fillmore, R.W.2    Borlongan, C.V.3    Sanberg, P.R.4
  • 8
    • 77955019118 scopus 로고    scopus 로고
    • Exendin-4 protects pancreatic beta cells from human islet amyloid polypeptide-induced cell damage: Potential involvement of AKT and mitochondria biogenesis
    • Fan, R.; Li, X.; Gu, X.; Chan, J. C.; Xu, G. Exendin-4 protects pancreatic beta cells from human islet amyloid polypeptide-induced cell damage: Potential involvement of AKT and mitochondria biogenesis. Diabetes Obes. Metab. 12(9):815-824; 2010.
    • (2010) Diabetes Obes. Metab. , vol.12 , Issue.9 , pp. 815-824
    • Fan, R.1    Li, X.2    Gu, X.3    Chan, J.C.4    Xu, G.5
  • 9
    • 0034068602 scopus 로고    scopus 로고
    • Pancreatic and duodenal homeobox gene 1 induces expression of insulin genes in liver and ameliorates streptozotocin-induced hyperglycemia
    • Ferber, S.; Halkin, A.; Cohen, H.; Ber, I.; Einav, Y.; Goldberg, I.; Barshack, I.; Seijffers, R.; Kopolovic, J.; Kaiser, N.; Karasik, A. Pancreatic and duodenal homeobox gene 1 induces expression of insulin genes in liver and ameliorates streptozotocin-induced hyperglycemia. Nat. Med. 6(5):568-572; 2000.
    • (2000) Nat. Med. , vol.6 , Issue.5 , pp. 568-572
    • Ferber, S.1    Halkin, A.2    Cohen, H.3    Ber, I.4    Einav, Y.5    Goldberg, I.6    Barshack, I.7    Seijffers, R.8    Kopolovic, J.9    Kaiser, N.10    Karasik, A.11
  • 10
    • 62649140098 scopus 로고    scopus 로고
    • Stem cell sources to treat diabetes
    • Furth, M. E.; Atala, A. Stem cell sources to treat diabetes. J. Cell. Biochem. 106(4):507-511; 2009.
    • (2009) J. Cell. Biochem. , vol.106 , Issue.4 , pp. 507-511
    • Furth, M.E.1    Atala, A.2
  • 11
    • 70350495679 scopus 로고    scopus 로고
    • Lytic infection of permissive cells with human cytomegalovirus is regulated by an intrinsic "pre-immediate-early" repression of viral gene expression mediated by histone post-translational modification
    • Groves, I. J.; Reeves, M. B.; Sinclair, J. H. Lytic infection of permissive cells with human cytomegalovirus is regulated by an intrinsic "pre-immediate-early" repression of viral gene expression mediated by histone post-translational modification. J. Gen. Virol. 90(Pt 10):2364-2374; 2009.
    • (2009) J. Gen. Virol. , vol.90 , Issue.PART 10 , pp. 2364-2374
    • Groves, I.J.1    Reeves, M.B.2    Sinclair, J.H.3
  • 12
    • 79951843726 scopus 로고    scopus 로고
    • Lack of evidence for recipient precursor cells replenishing beta-cells in transplanted islets
    • Hamamoto, Y.; Akashi, T.; Inada, A.; Bonner-Weir, S.; Weir, G. C. Lack of evidence for recipient precursor cells replenishing beta-cells in transplanted islets. Cell Transplant. 19(12):1563-1572; 2010.
    • (2010) Cell Transplant. , vol.19 , Issue.12 , pp. 1563-1572
    • Hamamoto, Y.1    Akashi, T.2    Inada, A.3    Bonner-Weir, S.4    Weir, G.C.5
  • 14
    • 34547857040 scopus 로고    scopus 로고
    • Generation of insulin-producing isletlike clusters from human embryonic stem cells
    • Jiang, J.; Au, M.; Lu, K.; Eshpeter, A.; Korbutt, G.; Fisk, G.; Majumdar, A. S. Generation of insulin-producing isletlike clusters from human embryonic stem cells. Stem Cells 25(8):1940-1953; 2007.
    • (2007) Stem Cells , vol.25 , Issue.8 , pp. 1940-1953
    • Jiang, J.1    Au, M.2    Lu, K.3    Eshpeter, A.4    Korbutt, G.5    Fisk, G.6    Majumdar, A.S.7
  • 15
    • 49249124292 scopus 로고    scopus 로고
    • Differentiation of mouse nuclear transfer embryonic stem cells into functional pancreatic beta cells
    • Jiang, W.; Bai, Z.; Zhang, D.; Shi, Y.; Yong, J.; Chen, S.; Ding, M.; Deng, H. Differentiation of mouse nuclear transfer embryonic stem cells into functional pancreatic beta cells. Diabetologia 51(9):1671-1679; 2008.
    • (2008) Diabetologia , vol.51 , Issue.9 , pp. 1671-1679
    • Jiang, W.1    Bai, Z.2    Zhang, D.3    Shi, Y.4    Yong, J.5    Chen, S.6    Ding, M.7    Deng, H.8
  • 17
    • 77953756833 scopus 로고    scopus 로고
    • Enhanced prediction of porcine islet yield and posttransplant outcome using a combination of quantitative histomorphometric parameters and flow cytometry
    • Jin, S. M.; Kim, K. S.; Lee, S. Y.; Gong, C. H.; Park, S. K.; Yu, J. E.; Yeom, S. C.; Yoon, T. W.; Ha, J.; Park, C. G.; Kim, S. J. Enhanced prediction of porcine islet yield and posttransplant outcome using a combination of quantitative histomorphometric parameters and flow cytometry. Cell Transplant. 19(3):299-311; 2010.
    • (2010) Cell Transplant. , vol.19 , Issue.3 , pp. 299-311
    • Jin, S.M.1    Kim, K.S.2    Lee, S.Y.3    Gong, C.H.4    Park, S.K.5    Yu, J.E.6    Yeom, S.C.7    Yoon, T.W.8    Ha, J.9    Park, C.G.10    Kim, S.J.11
  • 18
    • 0042767581 scopus 로고    scopus 로고
    • Pancreatic precursors and differentiated islet cell types from murine embryonic stem cells: An in vitro model to study islet differentiation
    • Kahan, B. W.; Jacobson, L. M.; Hullett, D. A.; Ochoada, J. M.; Oberley, T. D.; Lang, K. M.; Odorico, J. S. Pancreatic precursors and differentiated islet cell types from murine embryonic stem cells: An in vitro model to study islet differentiation. Diabetes 52(8):2016-2024; 2003.
    • (2003) Diabetes , vol.52 , Issue.8 , pp. 2016-2024
    • Kahan, B.W.1    Jacobson, L.M.2    Hullett, D.A.3    Ochoada, J.M.4    Oberley, T.D.5    Lang, K.M.6    Odorico, J.S.7
  • 20
    • 4544310572 scopus 로고    scopus 로고
    • In vitro directed differentiation of mouse embryonic stem cells into insulin-producing cells
    • Leon-Quinto, T.; Jones, J.; Skoudy, A.; Burcin, M.; Soria, B. In vitro directed differentiation of mouse embryonic stem cells into insulin-producing cells. Diabetologia 47(8):1442-1451; 2004.
    • (2004) Diabetologia , vol.47 , Issue.8 , pp. 1442-1451
    • Leon-Quinto, T.1    Jones, J.2    Skoudy, A.3    Burcin, M.4    Soria, B.5
  • 21
    • 51849144706 scopus 로고    scopus 로고
    • Coexpression of Pdx1 and betacellulin in mesenchymal stem cells could promote the differentiation of nestin-positive epithelium-like progenitors and pancreatic islet-like spheroids
    • Li, L.; Li, F.; Qi, H.; Feng, G.; Yuan, K.; Deng, H.; Zhou, H. Coexpression of Pdx1 and betacellulin in mesenchymal stem cells could promote the differentiation of nestin-positive epithelium-like progenitors and pancreatic islet-like spheroids. Stem Cells Dev. 17(4):815-823; 2008.
    • (2008) Stem Cells Dev. , vol.17 , Issue.4 , pp. 815-823
    • Li, L.1    Li, F.2    Qi, H.3    Feng, G.4    Yuan, K.5    Deng, H.6    Zhou, H.7
  • 22
    • 68849109257 scopus 로고    scopus 로고
    • Mouse ES cells over-expressing the transcription factor NeuroD1 show increased differentiation towards endocrine lineages and insulin-expressing cells
    • Marchand, M.; Schroeder, I. S.; Markossian, S.; Skoudy, A.; Negre, D.; Cosset, F. L.; Real, P.; Kaiser, C.; Wobus, A. M.; Savatier, P. Mouse ES cells over-expressing the transcription factor NeuroD1 show increased differentiation towards endocrine lineages and insulin-expressing cells. Int. J. Dev. Biol. 53(4):569-578; 2009.
    • (2009) Int. J. Dev. Biol. , vol.53 , Issue.4 , pp. 569-578
    • Marchand, M.1    Schroeder, I.S.2    Markossian, S.3    Skoudy, A.4    Negre, D.5    Cosset, F.L.6    Real, P.7    Kaiser, C.8    Wobus, A.M.9    Savatier, P.10
  • 24
    • 1542297749 scopus 로고    scopus 로고
    • The MafA transcription factor appears to be responsible for tissue-specific expression of insulin
    • Matsuoka, T. A.; Artner, I.; Henderson, E.; Means, A.; Sander, M.; Stein, R. The MafA transcription factor appears to be responsible for tissue-specific expression of insulin. Proc. Natl. Acad. Sci. USA 101(9):2930-2933; 2004.
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , Issue.9 , pp. 2930-2933
    • Matsuoka, T.A.1    Artner, I.2    Henderson, E.3    Means, A.4    Sander, M.5    Stein, R.6
  • 25
    • 0034775035 scopus 로고    scopus 로고
    • Pancreatic duodenal homeobox-1, PDX1, a major regulator of beta cell identity and function
    • McKinnon, C. M.; Docherty, K. Pancreatic duodenal homeobox-1, PDX1, a major regulator of beta cell identity and function. Diabetologia 44(10):1203-1214; 2001.
    • (2001) Diabetologia , vol.44 , Issue.10 , pp. 1203-1214
    • McKinnon, C.M.1    Docherty, K.2
  • 28
    • 1842527497 scopus 로고    scopus 로고
    • Regulated expression of pdx1 promotes in vitro differentiation of insulinproducing cells from embryonic stem cells
    • Miyazaki, S.; Yamato, E.; Miyazaki, J. Regulated expression of pdx1 promotes in vitro differentiation of insulinproducing cells from embryonic stem cells. Diabetes 53(4):1030-1037; 2004.
    • (2004) Diabetes , vol.53 , Issue.4 , pp. 1030-1037
    • Miyazaki, S.1    Yamato, E.2    Miyazaki, J.3
  • 29
    • 60549108411 scopus 로고    scopus 로고
    • A new experimental protocol for preferential differentiation of mouse embryonic stem cells into insulin-producing cells
    • Naujok, O.; Francini, F.; Picton, S.; Jorns, A.; Bailey, C. J.; Lenzen, S. A new experimental protocol for preferential differentiation of mouse embryonic stem cells into insulin-producing cells. Cell Transplant. 17(10-11):1231-1242; 2008.
    • (2008) Cell Transplant. , vol.17 , Issue.10-11 , pp. 1231-1242
    • Naujok, O.1    Francini, F.2    Picton, S.3    Jorns, A.4    Bailey, C.J.5    Lenzen, S.6
  • 30
    • 33947590955 scopus 로고    scopus 로고
    • Stem cells for the treatment of diabetes
    • Noguchi, H. Stem cells for the treatment of diabetes. Endocr. J. 54(1):7-16; 2007.
    • (2007) Endocr. J. , vol.54 , Issue.1 , pp. 7-16
    • Noguchi, H.1
  • 31
    • 33846639665 scopus 로고    scopus 로고
    • Induction of pancreatic stem/progenitor cells into insulin-producing cells by adenoviral-mediated gene transfer technology
    • Noguchi, H.; Xu, G.; Matsumoto, S.; Kaneto, H.; Kobayashi, N.; Bonner-Weir, S.; Hayashi, S. Induction of pancreatic stem/progenitor cells into insulin-producing cells by adenoviral-mediated gene transfer technology. Cell Transplant. 15(10):929-938; 2006.
    • (2006) Cell Transplant. , vol.15 , Issue.10 , pp. 929-938
    • Noguchi, H.1    Xu, G.2    Matsumoto, S.3    Kaneto, H.4    Kobayashi, N.5    Bonner-Weir, S.6    Hayashi, S.7
  • 32
    • 18444407829 scopus 로고    scopus 로고
    • Inducing embryonic stem cells to differentiate into pancreatic beta cells by a novel three-step approach with activin A and all-trans retinoic acid
    • Shi, Y.; Hou, L.; Tang, F.; Jiang, W.; Wang, P.; Ding, M.; Deng, H. Inducing embryonic stem cells to differentiate into pancreatic beta cells by a novel three-step approach with activin A and all-trans retinoic acid. Stem Cells 23(5):656-662; 2005.
    • (2005) Stem Cells , vol.23 , Issue.5 , pp. 656-662
    • Shi, Y.1    Hou, L.2    Tang, F.3    Jiang, W.4    Wang, P.5    Ding, M.6    Deng, H.7
  • 35
    • 0035495728 scopus 로고    scopus 로고
    • In-vitro differentiation of pancreatic beta-cells
    • Soria, B. In-vitro differentiation of pancreatic beta-cells. Differentiation 68(4-5):205-219; 2001.
    • (2001) Differentiation , vol.68 , Issue.4-5 , pp. 205-219
    • Soria, B.1
  • 36
    • 0033979603 scopus 로고    scopus 로고
    • Insulin-secreting cells derived from embryonic stem cells normalize glycemia in streptozotocin-induced diabetic mice
    • Soria, B.; Roche, E.; Berna, G.; Leon-Quinto, T.; Reig, J. A.; Martin, F. Insulin-secreting cells derived from embryonic stem cells normalize glycemia in streptozotocin-induced diabetic mice. Diabetes 49(2):157-162; 2000.
    • (2000) Diabetes , vol.49 , Issue.2 , pp. 157-162
    • Soria, B.1    Roche, E.2    Berna, G.3    Leon-Quinto, T.4    Reig, J.A.5    Martin, F.6
  • 37
    • 0024494423 scopus 로고
    • Germ line transmission and expression of a corrected HPRT gene produced by gene targeting in embryonic stem cells
    • Thompson, S.; Clarke, A. R.; Pow, A. M.; Hooper, M. L.; Melton, D. W. Germ line transmission and expression of a corrected HPRT gene produced by gene targeting in embryonic stem cells. Cell 56(2):313-321; 1989.
    • (1989) Cell , vol.56 , Issue.2 , pp. 313-321
    • Thompson, S.1    Clarke, A.R.2    Pow, A.M.3    Hooper, M.L.4    Melton, D.W.5
  • 39
    • 3242784958 scopus 로고    scopus 로고
    • Neurogenin 3 is a key transcription factor for differentiation of the endocrine pancreas
    • Watada, H. Neurogenin 3 is a key transcription factor for differentiation of the endocrine pancreas. Endocr. J. 51(3):255-264; 2004.
    • (2004) Endocr. J. , vol.51 , Issue.3 , pp. 255-264
    • Watada, H.1
  • 40
    • 0037931806 scopus 로고    scopus 로고
    • Distinct gene expression programs function in progenitor and mature islet cells
    • Watada, H.; Scheel, D. W.; Leung, J.; German, M. S. Distinct gene expression programs function in progenitor and mature islet cells. J. Biol. Chem. 278(19):17130-17140; 2003.
    • (2003) J. Biol. Chem. , vol.278 , Issue.19 , pp. 17130-17140
    • Watada, H.1    Scheel, D.W.2    Leung, J.3    German, M.S.4
  • 41
    • 53349178722 scopus 로고    scopus 로고
    • In vivo reprogramming of adult pancreatic exocrine cells to beta-cells
    • Zhou, Q.; Brown, J.; Kanarek, A.; Rajagopal, J.; Melton, D. A. In vivo reprogramming of adult pancreatic exocrine cells to beta-cells. Nature 455(7213):627-632; 2008.
    • (2008) Nature , vol.455 , Issue.7213 , pp. 627-632
    • Zhou, Q.1    Brown, J.2    Kanarek, A.3    Rajagopal, J.4    Melton, D.A.5
  • 42
    • 0035119871 scopus 로고    scopus 로고
    • Multipotential nestin-positive stem cells isolated from adult pancreatic islets differentiate ex vivo into pancreatic endocrine, exocrine, and hepatic phenotypes
    • Zulewski, H.; Abraham, E. J.; Gerlach, M. J.; Daniel, P. B.; Moritz, W.; Muller, B.; Vallejo, M.; Thomas, M. K.; Habener, J. F. Multipotential nestin-positive stem cells isolated from adult pancreatic islets differentiate ex vivo into pancreatic endocrine, exocrine, and hepatic phenotypes. Diabetes 50(3):521-533; 2001.
    • (2001) Diabetes , vol.50 , Issue.3 , pp. 521-533
    • Zulewski, H.1    Abraham, E.J.2    Gerlach, M.J.3    Daniel, P.B.4    Moritz, W.5    Muller, B.6    Vallejo, M.7    Thomas, M.K.8    Habener, J.F.9


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