메뉴 건너뛰기




Volumn 24, Issue 1, 2012, Pages 66-82

Major clinical research advances in gynecologic cancer in 2012

Author keywords

Bevacizumab; Image based high dose rate brachytherapy; Low risk endometrial cancer; PARP inhibitor; Practice guidelines

Indexed keywords

ANGIOPOIETIN 1; ANGIOPOIETIN 2; BEVACIZUMAB; BRCA1 ASSOCIATED RING DOMAIN PROTEIN 1; BRCA2 PROTEIN; CA 125 ANTIGEN; CAPECITABINE; CARBOPLATIN; CISPLATIN; DICER; DOCETAXEL; DOXORUBICIN; EPIDERMAL GROWTH FACTOR RECEPTOR 2; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE INHIBITOR; EPOTHILONE B; EVEROLIMUS; EXEMESTANE; GEMCITABINE; LAPATINIB; METFORMIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE INHIBITOR; OLAPARIB; PACLITAXEL; TEMSIROLIMUS; TRASTUZUMAB; TREBANANIB;

EID: 84873033900     PISSN: 20050380     EISSN: 20050399     Source Type: Journal    
DOI: 10.3802/jgo.2013.24.1.66     Document Type: Article
Times cited : (34)

References (114)
  • 3
    • 84861736119 scopus 로고    scopus 로고
    • OCEANS: A randomized, doubleblind, placebo-controlled phase III trial of chemotherapy with or without bevacizumab in patients with platinumsensitive recurrent epithelial ovarian, primary peritoneal, or fallopian tube cancer
    • Aghajanian C, Blank SV, Goff BA, Judson PL, Teneriello MG, Husain A, et al. OCEANS: a randomized, doubleblind, placebo-controlled phase III trial of chemotherapy with or without bevacizumab in patients with platinumsensitive recurrent epithelial ovarian, primary peritoneal, or fallopian tube cancer. J Clin Oncol 2012;30:2039-45.
    • (2012) J Clin Oncol , vol.30 , pp. 2039-2045
    • Aghajanian, C.1    Blank, S.V.2    Goff, B.A.3    Judson, P.L.4    Teneriello, M.G.5    Husain, A.6
  • 4
    • 84861736119 scopus 로고    scopus 로고
    • An updated safety analysis of OCEANS, a randomized, double-blind, phase III trial of gemcitabine (G) and carboplatin (C) with bevacizumab (BV) or placebo (PL) followed by BV or PL to disease progression (PD) in patients with platinum-sensitive (Plat-S) recurrent ovarian cancer
    • abstr 5054
    • Aghajanian C, Blank SV, Goff BA, Judson PL, Nycum LR, Sovak MA, et al. An updated safety analysis of OCEANS, a randomized, double-blind, phase III trial of gemcitabine (G) and carboplatin (C) with bevacizumab (BV) or placebo (PL) followed by BV or PL to disease progression (PD) in patients with platinum-sensitive (Plat-S) recurrent ovarian cancer. J Clin Oncol 2012;30:abstr 5054.
    • (2012) J Clin Oncol , vol.30
    • Aghajanian, C.1    Blank, S.V.2    Goff, B.A.3    Judson, P.L.4    Nycum, L.R.5    Sovak, M.A.6
  • 5
    • 84866493383 scopus 로고    scopus 로고
    • AURELIA: A randomized phase III trial evaluating bevacizumab (BEV) plus chemotherapy (CT) for platinum (PT)-resistant recurrent ovarian cancer (OC)
    • abstr LBA 5002
    • Pujade-Lauraine E, Hilpert F, Weber B, Reuss A, Poveda A, Kristensen G, et al. AURELIA: a randomized phase III trial evaluating bevacizumab (BEV) plus chemotherapy (CT) for platinum (PT)-resistant recurrent ovarian cancer (OC). J Clin Oncol 2012;30:abstr LBA 5002.
    • (2012) J Clin Oncol , vol.30
    • Pujade-Lauraine, E.1    Hilpert, F.2    Weber, B.3    Reuss, A.4    Poveda, A.5    Kristensen, G.6
  • 6
    • 84873026932 scopus 로고    scopus 로고
    • The effect of bevaxizumab (BEV) plus chemotherapy (CT) for platinum-resistant ovarian cancer (OC) with ascites: Analysis of the AURELIA trial
    • Kristensen G, Berton-Rigaud D, Hilpert F, Reuss A, Bover I, Raspagliesi F, et al. The effect of bevaxizumab (BEV) plus chemotherapy (CT) for platinum-resistant ovarian cancer (OC) with ascites: analysis of the AURELIA trial. Int J Gynecol Cancer 2012;22(8 suppl 3):E103.
    • (2012) Int J Gynecol Cancer , vol.22 , Issue.8 SUPPL. 3
    • Kristensen, G.1    Berton-Rigaud, D.2    Hilpert, F.3    Reuss, A.4    Bover, I.5    Raspagliesi, F.6
  • 7
    • 70349878651 scopus 로고    scopus 로고
    • Dose-dense paclitaxel once a week in combination with carboplatin every 3 weeks for advanced ovarian cancer: A phase 3, open-label, randomised controlled trial
    • Katsumata N, Yasuda M, Takahashi F, Isonishi S, Jobo T, Aoki D, et al. Dose-dense paclitaxel once a week in combination with carboplatin every 3 weeks for advanced ovarian cancer: a phase 3, open-label, randomised controlled trial. Lancet 2009;374:1331-8.
    • (2009) Lancet , vol.374 , pp. 1331-1338
    • Katsumata, N.1    Yasuda, M.2    Takahashi, F.3    Isonishi, S.4    Jobo, T.5    Aoki, D.6
  • 8
    • 84872199175 scopus 로고    scopus 로고
    • Safety of front-line bevacizumab (BEV) combined with weekly paclitaxel (wPAC) and q3w carboplatin (C) for ovarian cancer (OC): Results from OCTAVIA
    • abstr 5017
    • Gonzalez-Martin A, Gladieff L, Tholander B, Stroyakovsky D, Gore ME, Segalla JGM, et al. Safety of front-line bevacizumab (BEV) combined with weekly paclitaxel (wPAC) and q3w carboplatin (C) for ovarian cancer (OC): Results from OCTAVIA. J Clin Oncol 2012;30:abstr 5017.
    • (2012) J Clin Oncol , vol.30
    • Gonzalez-Martin, A.1    Gladieff, L.2    Tholander, B.3    Stroyakovsky, D.4    Gore, M.E.5    Segalla, J.G.M.6
  • 9
    • 84866152751 scopus 로고    scopus 로고
    • Bevacizumab (BEV) plus chemotherapy (CT) continued beyond first progression in patients with metastatic colorectal cancer (mCRC) previously treated with BEV plus CT: Results of a randomized phase III intergroup study (TML study)
    • abstr CRA 3503
    • Arnold D, Andre T, Bennouna J, Sastre J, Osterlund PJ, Greil R, et al. Bevacizumab (BEV) plus chemotherapy (CT) continued beyond first progression in patients with metastatic colorectal cancer (mCRC) previously treated with BEV plus CT: results of a randomized phase III intergroup study (TML study). J Clin Oncol 2012;30:abstr CRA 3503.
    • (2012) J Clin Oncol , vol.30
    • Arnold, D.1    Andre, T.2    Bennouna, J.3    Sastre, J.4    Osterlund, P.J.5    Greil, R.6
  • 10
    • 84873023889 scopus 로고    scopus 로고
    • Bevacizumab beyond progression is not associated with prolonged progression-free survival in epithelial ovarian cancer
    • Previs R, Perry L, Sperling J, Brevis K, McCann G, Moore K, et al. Bevacizumab beyond progression is not associated with prolonged progression-free survival in epithelial ovarian cancer. Int J Gynecol Cancer 2012;22(8 suppl 3): E220.
    • (2012) Int J Gynecol Cancer , vol.22 , Issue.8 SUPPL. 3
    • Previs, R.1    Perry, L.2    Sperling, J.3    Brevis, K.4    McCann, G.5    Moore, K.6
  • 11
    • 79952747328 scopus 로고    scopus 로고
    • Nonhomologous end joining drives poly(ADP-ribose) polymerase (PARP) inhibitor lethality in homologous recombinationdeficient cells
    • Patel AG, Sarkaria JN, Kaufmann SH. Nonhomologous end joining drives poly(ADP-ribose) polymerase (PARP) inhibitor lethality in homologous recombinationdeficient cells. Proc Natl Acad Sci U S A 2011;108:3406-11.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 3406-3411
    • Patel, A.G.1    Sarkaria, J.N.2    Kaufmann, S.H.3
  • 12
    • 84856731422 scopus 로고    scopus 로고
    • Comparing poly (ADP-ribose) polymerase inhibitors with standard chemotherapy in BRCA-mutated, recurrent ovarian cancer: Lessons learned from a negative trial
    • Konstantinopoulos PA, Cannistra SA. Comparing poly (ADP-ribose) polymerase inhibitors with standard chemotherapy in BRCA-mutated, recurrent ovarian cancer: lessons learned from a negative trial. J Clin Oncol 2012;30:347-50.
    • (2012) J Clin Oncol , vol.30 , pp. 347-350
    • Konstantinopoulos, P.A.1    Cannistra, S.A.2
  • 13
    • 77954700380 scopus 로고    scopus 로고
    • Phase III study of bevacizumab plus docetaxel compared with placebo plus docetaxel for the first-line treatment of human epidermal growth factor receptor 2-negative metastatic breast cancer
    • Miles DW, Chan A, Dirix LY, Cortes J, Pivot X, Tomczak P, et al. Phase III study of bevacizumab plus docetaxel compared with placebo plus docetaxel for the first-line treatment of human epidermal growth factor receptor 2-negative metastatic breast cancer. J Clin Oncol 2010;28:3239-47.
    • (2010) J Clin Oncol , vol.28 , pp. 3239-3247
    • Miles, D.W.1    Chan, A.2    Dirix, L.Y.3    Cortes, J.4    Pivot, X.5    Tomczak, P.6
  • 14
    • 55949092708 scopus 로고    scopus 로고
    • High sensitivity of BRCA1-deficient mammary tumors to the PARP inhibitor AZD2281 alone and in combination with platinum drugs
    • Rottenberg S, Jaspers JE, Kersbergen A, van der Burg E, Nygren AO, Zander SA, et al. High sensitivity of BRCA1-deficient mammary tumors to the PARP inhibitor AZD2281 alone and in combination with platinum drugs. Proc Natl Acad Sci U S A 2008;105:17079-84.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 17079-17084
    • Rottenberg, S.1    Jaspers, J.E.2    Kersbergen, A.3    van der Burg, E.4    Nygren, A.O.5    Zander, S.A.6
  • 15
    • 84863010984 scopus 로고    scopus 로고
    • Phase II, open-label, randomized, multicenter study comparing the efficacy and safety of olaparib, a poly (ADP-ribose) polymerase inhibitor, and pegylated liposomal doxorubicin in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer
    • Kaye SB, Lubinski J, Matulonis U, Ang JE, Gourley C, Karlan BY, et al. Phase II, open-label, randomized, multicenter study comparing the efficacy and safety of olaparib, a poly (ADP-ribose) polymerase inhibitor, and pegylated liposomal doxorubicin in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer. J Clin Oncol 2012;30:372-9.
    • (2012) J Clin Oncol , vol.30 , pp. 372-379
    • Kaye, S.B.1    Lubinski, J.2    Matulonis, U.3    Ang, J.E.4    Gourley, C.5    Karlan, B.Y.6
  • 16
    • 77955039099 scopus 로고    scopus 로고
    • Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer: A proofof-concept trial
    • Audeh MW, Carmichael J, Penson RT, Friedlander M, Powell B, Bell-McGuinn KM, et al. Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer: a proofof-concept trial. Lancet 2010;376:245-51.
    • (2010) Lancet , vol.376 , pp. 245-251
    • Audeh, M.W.1    Carmichael, J.2    Penson, R.T.3    Friedlander, M.4    Powell, B.5    Bell-McGuinn, K.M.6
  • 17
    • 77954032829 scopus 로고    scopus 로고
    • Poly(ADP)-ribose polymerase inhibition: Frequent durable responses in BRCA carrier ovarian cancer correlating with platinum-free interval
    • Fong PC, Yap TA, Boss DS, Carden CP, Mergui-Roelvink M, Gourley C, et al. Poly(ADP)-ribose polymerase inhibition: frequent durable responses in BRCA carrier ovarian cancer correlating with platinum-free interval. J Clin Oncol 2010;28:2512-9.
    • (2010) J Clin Oncol , vol.28 , pp. 2512-2519
    • Fong, P.C.1    Yap, T.A.2    Boss, D.S.3    Carden, C.P.4    Mergui-Roelvink, M.5    Gourley, C.6
  • 18
    • 0035879099 scopus 로고    scopus 로고
    • Recurrent epithelial ovarian carcinoma: A randomized phase III study of pegylated liposomal doxorubicin versus topotecan
    • Gordon AN, Fleagle JT, Guthrie D, Parkin DE, Gore ME, Lacave AJ. Recurrent epithelial ovarian carcinoma: a randomized phase III study of pegylated liposomal doxorubicin versus topotecan. J Clin Oncol 2001;19:3312-22.
    • (2001) J Clin Oncol , vol.19 , pp. 3312-3322
    • Gordon, A.N.1    Fleagle, J.T.2    Guthrie, D.3    Parkin, D.E.4    Gore, M.E.5    Lacave, A.J.6
  • 19
    • 80053950209 scopus 로고    scopus 로고
    • Association of BRCA1 and BRCA2 mutations with survival, chemotherapy sensitivity, and gene mutator phenotype in patients with ovarian cancer
    • Yang D, Khan S, Sun Y, Hess K, Shmulevich I, Sood AK, et al. Association of BRCA1 and BRCA2 mutations with survival, chemotherapy sensitivity, and gene mutator phenotype in patients with ovarian cancer. JAMA 2011;306:1557-65.
    • (2011) JAMA , vol.306 , pp. 1557-1565
    • Yang, D.1    Khan, S.2    Sun, Y.3    Hess, K.4    Shmulevich, I.5    Sood, A.K.6
  • 20
    • 39849106300 scopus 로고    scopus 로고
    • Secondary mutations as a mechanism of cisplatin resistance in BRCA2-mutated cancers
    • Sakai W, Swisher EM, Karlan BY, Agarwal MK, Higgins J, Friedman C, et al. Secondary mutations as a mechanism of cisplatin resistance in BRCA2-mutated cancers. Nature 2008;451:1116-20.
    • (2008) Nature , vol.451 , pp. 1116-1120
    • Sakai, W.1    Swisher, E.M.2    Karlan, B.Y.3    Agarwal, M.K.4    Higgins, J.5    Friedman, C.6
  • 22
    • 84867062943 scopus 로고    scopus 로고
    • Randomized phase III study of erlotinib versus observation in patients with no evidence of disease progression after first-line platin-based chemotherapy for ovarian carcinoma: A GCIG and EORTC-GCG study
    • abstr LBA 5000
    • Vergote IB, Joly F, Katsaros D, Coens C, Reinthaller A, Hall M, et al. Randomized phase III study of erlotinib versus observation in patients with no evidence of disease progression after first-line platin-based chemotherapy for ovarian carcinoma: a GCIG and EORTC-GCG study. J Clin Oncol 2012;30:abstr LBA 5000.
    • (2012) J Clin Oncol , vol.30
    • Vergote, I.B.1    Joly, F.2    Katsaros, D.3    Coens, C.4    Reinthaller, A.5    Hall, M.6
  • 23
    • 84869109927 scopus 로고    scopus 로고
    • Randomized, open-label, phase III study comparing patupilone (EPO906) with pegylated liposomal doxorubicin in platinum-refractory or-resistant patients with recurrent epithelial ovarian, primary fallopian tube, or primary peritoneal cancer
    • Colombo N, Kutarska E, Dimopoulos M, Bae DS, Rzepka-Gorska I, Bidzinski M, et al. Randomized, open-label, phase III study comparing patupilone (EPO906) with pegylated liposomal doxorubicin in platinum-refractory or-resistant patients with recurrent epithelial ovarian, primary fallopian tube, or primary peritoneal cancer. J Clin Oncol 2012;30:3841-7.
    • (2012) J Clin Oncol , vol.30 , pp. 3841-3847
    • Colombo, N.1    Kutarska, E.2    Dimopoulos, M.3    Bae, D.S.4    Rzepka-Gorska, I.5    Bidzinski, M.6
  • 24
    • 0031027531 scopus 로고    scopus 로고
    • Activities of the microtubule-stabilizing agents epothilones A and B with purified tubulin and in cells resistant to paclitaxel (Taxol(R)
    • Kowalski RJ, Giannakakou P, Hamel E. Activities of the microtubule-stabilizing agents epothilones A and B with purified tubulin and in cells resistant to paclitaxel (Taxol(R). J Biol Chem 1997;272:2534-41.
    • (1997) J Biol Chem , vol.272 , pp. 2534-2541
    • Kowalski, R.J.1    Giannakakou, P.2    Hamel, E.3
  • 25
    • 0034678986 scopus 로고    scopus 로고
    • Epothilones and related structures: A new class of microtubule inhibitors with potent in vivo antitumor activity
    • Altmann KH, Wartmann M, O'Reilly T. Epothilones and related structures: a new class of microtubule inhibitors with potent in vivo antitumor activity. Biochim Biophys Acta 2000;1470:M79-91.
    • (2000) Biochim Biophys Acta , vol.1470
    • Altmann, K.H.1    Wartmann, M.2    O'Reilly, T.3
  • 26
    • 67650318481 scopus 로고    scopus 로고
    • Safety and efficacy of patupilone in patients with advanced ovarian, primary fallopian, or primary peritoneal cancer: A phase I, openlabel, dose-escalation study
    • Ten Bokkel Huinink WW, Sufliarsky J, Smit WM, Spanik S, Wagnerova M, Hirte HW, et al. Safety and efficacy of patupilone in patients with advanced ovarian, primary fallopian, or primary peritoneal cancer: a phase I, openlabel, dose-escalation study. J Clin Oncol 2009;27:3097-103.
    • (2009) J Clin Oncol , vol.27 , pp. 3097-3103
    • Ten Bokkel Huinink, W.W.1    Sufliarsky, J.2    Smit, W.M.3    Spanik, S.4    Wagnerova, M.5    Hirte, H.W.6
  • 27
    • 0038745370 scopus 로고    scopus 로고
    • Tumor-derived vascular endothelial growth factor up-regulates angiopoietin-2 in host endothelium and destabilizes host vasculature, supporting angiogenesis in ovarian cancer
    • Zhang L, Yang N, Park JW, Katsaros D, Fracchioli S, Cao G, et al. Tumor-derived vascular endothelial growth factor up-regulates angiopoietin-2 in host endothelium and destabilizes host vasculature, supporting angiogenesis in ovarian cancer. Cancer Res 2003;63:3403-12.
    • (2003) Cancer Res , vol.63 , pp. 3403-3412
    • Zhang, L.1    Yang, N.2    Park, J.W.3    Katsaros, D.4    Fracchioli, S.5    Cao, G.6
  • 28
    • 36849056497 scopus 로고    scopus 로고
    • Phase II study of bevacizumab in patients with platinum-resistant ovarian cancer or peritoneal serous cancer
    • Cannistra SA, Matulonis UA, Penson RT, Hambleton J, Dupont J, Mackey H, et al. Phase II study of bevacizumab in patients with platinum-resistant ovarian cancer or peritoneal serous cancer. J Clin Oncol 2007;25:5180-6.
    • (2007) J Clin Oncol , vol.25 , pp. 5180-5186
    • Cannistra, S.A.1    Matulonis, U.A.2    Penson, R.T.3    Hambleton, J.4    Dupont, J.5    McKey, H.6
  • 29
    • 70249114453 scopus 로고    scopus 로고
    • Safety, pharmacokinetics, and antitumor activity of AMG 386, a selective angiopoietin inhibitor, in adult patients with advanced solid tumors
    • Herbst RS, Hong D, Chap L, Kurzrock R, Jackson E, Silverman JM, et al. Safety, pharmacokinetics, and antitumor activity of AMG 386, a selective angiopoietin inhibitor, in adult patients with advanced solid tumors. J Clin Oncol 2009;27:3557-65.
    • (2009) J Clin Oncol , vol.27 , pp. 3557-3565
    • Herbst, R.S.1    Hong, D.2    Chap, L.3    Kurzrock, R.4    Jackson, E.5    Silverman, J.M.6
  • 30
    • 77953097101 scopus 로고    scopus 로고
    • Phase 1 study of AMG 386, a selective angiopoietin 1/2-neutralizing peptibody, in combination with chemotherapy in adults with advanced solid tumors
    • Mita AC, Takimoto CH, Mita M, Tolcher A, Sankhala K, Sarantopoulos J, et al. Phase 1 study of AMG 386, a selective angiopoietin 1/2-neutralizing peptibody, in combination with chemotherapy in adults with advanced solid tumors. Clin Cancer Res 2010;16:3044-56.
    • (2010) Clin Cancer Res , vol.16 , pp. 3044-3056
    • Mita, A.C.1    Takimoto, C.H.2    Mita, M.3    Tolcher, A.4    Sankhala, K.5    Sarantopoulos, J.6
  • 31
    • 84863012011 scopus 로고    scopus 로고
    • Randomized, double-blind, placebo-controlled phase II study of AMG 386 combined with weekly paclitaxel in patients with recurrent ovarian cancer
    • Karlan BY, Oza AM, Richardson GE, Provencher DM, Hansen VL, Buck M, et al. Randomized, double-blind, placebo-controlled phase II study of AMG 386 combined with weekly paclitaxel in patients with recurrent ovarian cancer. J Clin Oncol 2012;30:362-71.
    • (2012) J Clin Oncol , vol.30 , pp. 362-371
    • Karlan, B.Y.1    Oza, A.M.2    Richardson, G.E.3    Provencher, D.M.4    Hansen, V.L.5    Buck, M.6
  • 32
    • 84873028344 scopus 로고    scopus 로고
    • Phase III HECTOR study: Recurring platinum sensitive ovarian cancer [Internet]
    • [cited 2012 Nov 25]. Available from:
    • Mahner S. Phase III HECTOR study: recurring platinum sensitive ovarian cancer [Internet]. Cancer Intelligence; 2012 [cited 2012 Nov 25]. Available from: http://ecancer. org/tv/conference/157/1688.
    • (2012) Cancer Intelligence
    • Mahner, S.1
  • 33
    • 45749148248 scopus 로고    scopus 로고
    • Topotecan and carboplatin in patients with platinum-sensitive recurrent ovarian cancer: Results of a multicenter NOGGO: Phase I/II study
    • Koensgen D, Stengel D, Belau A, Klare P, Oskay-Oezcelik G, Steck T, et al. Topotecan and carboplatin in patients with platinum-sensitive recurrent ovarian cancer: results of a multicenter NOGGO: phase I/II study. Cancer Chemother Pharmacol 2008;62:393-400.
    • (2008) Cancer Chemother Pharmacol , vol.62 , pp. 393-400
    • Koensgen, D.1    Stengel, D.2    Belau, A.3    Klare, P.4    Oskay-Oezcelik, G.5    Steck, T.6
  • 34
    • 78649907376 scopus 로고    scopus 로고
    • An open-label, single-arm phase II study of intravenous weekly (days 1 and 8) topotecan in combination with carboplatin (day 1) every 21 days as secondline therapy in patients with platinum-sensitive relapsed ovarian cancer
    • Rose PG, Monk BJ, Provencher D, Hartney J, Legenne P, Lane S. An open-label, single-arm phase II study of intravenous weekly (days 1 and 8) topotecan in combination with carboplatin (day 1) every 21 days as secondline therapy in patients with platinum-sensitive relapsed ovarian cancer. Gynecol Oncol 2011;120:38-42.
    • (2011) Gynecol Oncol , vol.120 , pp. 38-42
    • Rose, P.G.1    Monk, B.J.2    Provencher, D.3    Hartney, J.4    Legenne, P.5    Lane, S.6
  • 35
    • 84870317593 scopus 로고    scopus 로고
    • Long-term follow-up of a rancomized trial comparing conventional paclitaxel and carboplatin with dose-dense weekly paclitaxel and carboplatin in women with advanced epithelial ovarian, fallopian tube, or primary peritoneal cancer: JGOG 3016 trial
    • abstr 5003
    • Katsumata N, Yasuda M, Isonishi S, Michimae H, Kimura E, Aoki D, et al. Long-term follow-up of a rancomized trial comparing conventional paclitaxel and carboplatin with dose-dense weekly paclitaxel and carboplatin in women with advanced epithelial ovarian, fallopian tube, or primary peritoneal cancer: JGOG 3016 trial. J Clin Oncol 2012;30:abstr 5003.
    • (2012) J Clin Oncol , vol.30
    • Katsumata, N.1    Yasuda, M.2    Isonishi, S.3    Michimae, H.4    Kimura, E.5    Aoki, D.6
  • 36
    • 77953337981 scopus 로고    scopus 로고
    • Major clinical research advances in gynecologic cancer 2009
    • Kim K, Ryu SY. Major clinical research advances in gynecologic cancer 2009. J Gynecol Oncol 2009;20:203-9.
    • (2009) J Gynecol Oncol , vol.20 , pp. 203-209
    • Kim, K.1    Ryu, S.Y.2
  • 37
    • 79959838081 scopus 로고    scopus 로고
    • Integrated genomic analyses of ovarian carcinoma
    • Cancer Genome Atlas Research Network
    • Cancer Genome Atlas Research Network. Integrated genomic analyses of ovarian carcinoma. Nature 2011;474:609-15.
    • (2011) Nature , vol.474 , pp. 609-615
  • 38
    • 84873042599 scopus 로고    scopus 로고
    • Is it necessary to screen everybody for inherited cancer? when, why and how
    • Levy-Lahad E. Is it necessary to screen everybody for inherited cancer? when, why and how. Ann Oncol 2012;23(suppl 9):ix34.
    • (2012) Ann Oncol , vol.23 , Issue.SUPPL. 9
    • Levy-Lahad, E.1
  • 39
    • 84863275781 scopus 로고    scopus 로고
    • Major clinical research advances in gynecologic cancer in 2011
    • Suh DH, Kim K, Kim JW. Major clinical research advances in gynecologic cancer in 2011. J Gynecol Oncol 2012;23:53-64.
    • (2012) J Gynecol Oncol , vol.23 , pp. 53-64
    • Suh, D.H.1    Kim, K.2    Kim, J.W.3
  • 40
    • 84873019398 scopus 로고    scopus 로고
    • Challenges of dealing with next generation sequencing for hereditary cancer in clinical practice
    • Claes K. Challenges of dealing with next generation sequencing for hereditary cancer in clinical practice. Ann Oncol 2012;23(suppl 9):ix33.
    • (2012) Ann Oncol , vol.23 , Issue.SUPPL. 9
    • Claes, K.1
  • 41
    • 84856158117 scopus 로고    scopus 로고
    • Association between BRCA1 and BRCA2 mutations and survival in women with invasive epithelial ovarian cancer
    • Bolton KL, Chenevix-Trench G, Goh C, Sadetzki S, Ramus SJ, Karlan BY, et al. Association between BRCA1 and BRCA2 mutations and survival in women with invasive epithelial ovarian cancer. JAMA 2012;307:382-90.
    • (2012) JAMA , vol.307 , pp. 382-390
    • Bolton, K.L.1    Chenevix-Trench, G.2    Goh, C.3    Sadetzki, S.4    Ramus, S.J.5    Karlan, B.Y.6
  • 42
    • 37849030476 scopus 로고    scopus 로고
    • Effect of BRCA1/2 mutations on long-term survival of patients with invasive ovarian cancer: The national Israeli study of ovarian cancer
    • Chetrit A, Hirsh-Yechezkel G, Ben-David Y, Lubin F, Friedman E, Sadetzki S. Effect of BRCA1/2 mutations on long-term survival of patients with invasive ovarian cancer: the national Israeli study of ovarian cancer. J Clin Oncol 2008;26:20-5.
    • (2008) J Clin Oncol , vol.26 , pp. 20-25
    • Chetrit, A.1    Hirsh-Yechezkel, G.2    Ben-David, Y.3    Lubin, F.4    Friedman, E.5    Sadetzki, S.6
  • 46
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: Genomics, biogenesis, mechanism, and function
    • Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 2004;116:281-97.
    • (2004) Cell , vol.116 , pp. 281-297
    • Bartel, D.P.1
  • 47
    • 66549084297 scopus 로고    scopus 로고
    • Non-epithelial ovarian cancer: ESMO clinical recommendations for diagnosis, treatment and follow-up
    • Colombo N, Peiretti M, Castiglione M. Non-epithelial ovarian cancer: ESMO clinical recommendations for diagnosis, treatment and follow-up. Ann Oncol 2009;20 Suppl 4:24-6.
    • (2009) Ann Oncol , vol.20 , Issue.SUPPL. 4 , pp. 24-26
    • Colombo, N.1    Peiretti, M.2    Castiglione, M.3
  • 49
    • 84863338519 scopus 로고    scopus 로고
    • PI3K/AKT/mTOR inhibitors in patients with breast and gynecologic malignancies harboring PIK3CA mutations
    • Janku F, Wheler JJ, Westin SN, Moulder SL, Naing A, Tsimberidou AM, et al. PI3K/AKT/mTOR inhibitors in patients with breast and gynecologic malignancies harboring PIK3CA mutations. J Clin Oncol 2012;30:777-82.
    • (2012) J Clin Oncol , vol.30 , pp. 777-782
    • Janku, F.1    Wheler, J.J.2    Westin, S.N.3    Moulder, S.L.4    Naing, A.5    Tsimberidou, A.M.6
  • 51
    • 38949121953 scopus 로고    scopus 로고
    • PIK3CA gene mutations and amplifications in uterine cancers, identified by methods that avoid confounding by PIK3CA pseudogene sequences
    • Miyake T, Yoshino K, Enomoto T, Takata T, Ugaki H, Kim A, et al. PIK3CA gene mutations and amplifications in uterine cancers, identified by methods that avoid confounding by PIK3CA pseudogene sequences. Cancer Lett 2008;261:120-6.
    • (2008) Cancer Lett , vol.261 , pp. 120-126
    • Miyake, T.1    Yoshino, K.2    Enomoto, T.3    Takata, T.4    Ugaki, H.5    Kim, A.6
  • 53
    • 77955288855 scopus 로고    scopus 로고
    • Deregulation of the PI3K and KRAS signaling pathways in human cancer cells determines their response to everolimus
    • Di Nicolantonio F, Arena S, Tabernero J, Grosso S, Molinari F, Macarulla T, et al. Deregulation of the PI3K and KRAS signaling pathways in human cancer cells determines their response to everolimus. J Clin Invest 2010;120:2858-66.
    • (2010) J Clin Invest , vol.120 , pp. 2858-2866
    • Di Nicolantonio, F.1    Arena, S.2    Tabernero, J.3    Grosso, S.4    Molinari, F.5    McArulla, T.6
  • 54
    • 0033784805 scopus 로고    scopus 로고
    • Hormonal treatment of endometrial cancer
    • Emons G, Heyl W. Hormonal treatment of endometrial cancer. J Cancer Res Clin Oncol 2000;126:619-23.
    • (2000) J Cancer Res Clin Oncol , vol.126 , pp. 619-623
    • Emons, G.1    Heyl, W.2
  • 55
    • 33847662544 scopus 로고    scopus 로고
    • Chemotherapy for advanced, recurrent or metastatic endometrial cancer: A systematic review of Cochrane collaboration
    • Humber CE, Tierney JF, Symonds RP, Collingwood M, Kirwan J, Williams C, et al. Chemotherapy for advanced, recurrent or metastatic endometrial cancer: a systematic review of Cochrane collaboration. Ann Oncol 2007;18:409-20.
    • (2007) Ann Oncol , vol.18 , pp. 409-420
    • Humber, C.E.1    Tierney, J.F.2    Symonds, R.P.3    Collingwood, M.4    Kirwan, J.5    Williams, C.6
  • 56
    • 80052010923 scopus 로고    scopus 로고
    • Phase II study of temsirolimus in women with recurrent or metastatic endometrial cancer: A trial of the NCIC Clinical Trials Group
    • Oza AM, Elit L, Tsao MS, Kamel-Reid S, Biagi J, Provencher DM, et al. Phase II study of temsirolimus in women with recurrent or metastatic endometrial cancer: a trial of the NCIC Clinical Trials Group. J Clin Oncol 2011;29:3278-85.
    • (2011) J Clin Oncol , vol.29 , pp. 3278-3285
    • Oza, A.M.1    Elit, L.2    Tsao, M.S.3    Kamel-Reid, S.4    Biagi, J.5    Provencher, D.M.6
  • 57
    • 84873023915 scopus 로고    scopus 로고
    • New therapies to treat advanced endometrial cancer [Internet]
    • [cited 2012 Nov 25]. Available from:
    • Fleming G. New therapies to treat advanced endometrial cancer [Internet]. Cancer Intelligence; 2012 [cited 2012 Nov 25]. Available from: http://ecancer.org/tv/ pubdate/1676.
    • (2012) Cancer Intelligence
    • Fleming, G.1
  • 58
    • 84860226762 scopus 로고    scopus 로고
    • Clinicopathological and prognostic impact of human epidermal growth factor receptor type 2 (HER2) and hormone receptor expression in uterine papillary serous carcinoma
    • Togami S, Sasajima Y, Oi T, Ishikawa M, Onda T, Ikeda S, et al. Clinicopathological and prognostic impact of human epidermal growth factor receptor type 2 (HER2) and hormone receptor expression in uterine papillary serous carcinoma. Cancer Sci 2012;103:926-32.
    • (2012) Cancer Sci , vol.103 , pp. 926-932
    • Togami, S.1    Sasajima, Y.2    Oi, T.3    Ishikawa, M.4    Onda, T.5    Ikeda, S.6
  • 59
    • 67349200943 scopus 로고    scopus 로고
    • Adjuvant carboplatin and paclitaxel chemotherapy interposed with involved field radiation for advanced endometrial cancer
    • Lupe K, D'Souza DP, Kwon JS, Radwan JS, Harle IA, Hammond JA, et al. Adjuvant carboplatin and paclitaxel chemotherapy interposed with involved field radiation for advanced endometrial cancer. Gynecol Oncol 2009;114:94-8.
    • (2009) Gynecol Oncol , vol.114 , pp. 94-98
    • Lupe, K.1    D'Souza, D.P.2    Kwon, J.S.3    Radwan, J.S.4    Harle, I.A.5    Hammond, J.A.6
  • 60
    • 79251596941 scopus 로고    scopus 로고
    • Prospective, non-randomized phase 2 clinical trial of carboplatin plus paclitaxel with sequential radical pelvic radiotherapy for uterine papillary serous carcinoma
    • Obermair A, Mileshkin L, Bolz K, Kondalsamy-Chennakesavan S, Cheuk R, Vasey P, et al. Prospective, non-randomized phase 2 clinical trial of carboplatin plus paclitaxel with sequential radical pelvic radiotherapy for uterine papillary serous carcinoma. Gynecol Oncol 2011;120:179-84.
    • (2011) Gynecol Oncol , vol.120 , pp. 179-184
    • Obermair, A.1    Mileshkin, L.2    Bolz, K.3    Kondalsamy-Chennakesavan, S.4    Cheuk, R.5    Vasey, P.6
  • 61
    • 77953288236 scopus 로고    scopus 로고
    • A single institution experience using sequential multi-modality adjuvant chemotherapy and radiation in the "sandwich" method for high risk endometrial carcinoma
    • Geller MA, Ivy J, Dusenbery KE, Ghebre R, Isaksson Vogel R, Argenta PA. A single institution experience using sequential multi-modality adjuvant chemotherapy and radiation in the "sandwich" method for high risk endometrial carcinoma. Gynecol Oncol 2010;118:19-23.
    • (2010) Gynecol Oncol , vol.118 , pp. 19-23
    • Geller, M.A.1    Ivy, J.2    Dusenbery, K.E.3    Ghebre, R.4    Isaksson Vogel, R.5    Argenta, P.A.6
  • 62
    • 79952817755 scopus 로고    scopus 로고
    • A phase II trial of carboplatin and docetaxel followed by radiotherapy given in a "Sandwich" method for stage III, IV, and recurrent endometrial cancer
    • Geller MA, Ivy JJ, Ghebre R, Downs LS Jr, Judson PL, Carson LF, et al. A phase II trial of carboplatin and docetaxel followed by radiotherapy given in a "Sandwich" method for stage III, IV, and recurrent endometrial cancer. Gynecol Oncol 2011;121:112-7.
    • (2011) Gynecol Oncol , vol.121 , pp. 112-117
    • Geller, M.A.1    Ivy, J.J.2    Ghebre, R.3    Downs Jr., L.S.4    Judson, P.L.5    Carson, L.F.6
  • 63
    • 83055186625 scopus 로고    scopus 로고
    • Phase II trial of adjuvant pelvic radiation "sandwiched" between combination paclitaxel and carboplatin in women with uterine papillary serous carcinoma
    • Einstein MH, Frimer M, Kuo DY, Reimers LL, Mehta K, Mutyala S, et al. Phase II trial of adjuvant pelvic radiation "sandwiched" between combination paclitaxel and carboplatin in women with uterine papillary serous carcinoma. Gynecol Oncol 2012;124:21-5.
    • (2012) Gynecol Oncol , vol.124 , pp. 21-25
    • Einstein, M.H.1    Frimer, M.2    Kuo, D.Y.3    Reimers, L.L.4    Mehta, K.5    Mutyala, S.6
  • 64
    • 37349112426 scopus 로고    scopus 로고
    • Pilot phase II trial of radiation "sandwiched" between combination paclitaxel/platinum chemotherapy in patients with uterine papillary serous carcinoma (UPSC)
    • Fields AL, Einstein MH, Novetsky AP, Gebb J, Goldberg GL. Pilot phase II trial of radiation "sandwiched" between combination paclitaxel/platinum chemotherapy in patients with uterine papillary serous carcinoma (UPSC). Gynecol Oncol 2008;108:201-6.
    • (2008) Gynecol Oncol , vol.108 , pp. 201-206
    • Fields, A.L.1    Einstein, M.H.2    Novetsky, A.P.3    Gebb, J.4    Goldberg, G.L.5
  • 65
    • 57349198710 scopus 로고    scopus 로고
    • Systematic pelvic lymphadenectomy vs. no lymphadenectomy in earlystage endometrial carcinoma: Randomized clinical trial
    • Benedetti Panici P, Basile S, Maneschi F, Alberto Lissoni A, Signorelli M, Scambia G, et al. Systematic pelvic lymphadenectomy vs. no lymphadenectomy in earlystage endometrial carcinoma: randomized clinical trial. J Natl Cancer Inst 2008;100:1707-16.
    • (2008) J Natl Cancer Inst , vol.100 , pp. 1707-1716
    • Benedetti Panici, P.1    Basile, S.2    Maneschi, F.3    Alberto Lissoni, A.4    Signorelli, M.5    Scambia, G.6
  • 66
    • 58149191223 scopus 로고    scopus 로고
    • Efficacy of systematic pelvic lymphadenectomy in endometrial cancer (MRC ASTEC trial): A randomised study
    • Kitchener H, Swart AM, Qian Q, Amos C, Parmar MK. Efficacy of systematic pelvic lymphadenectomy in endometrial cancer (MRC ASTEC trial): a randomised study. Lancet 2009;373:125-36.
    • (2009) Lancet , vol.373 , pp. 125-136
    • Kitchener, H.1    Swart, A.M.2    Qian, Q.3    Amos, C.4    Parmar, M.K.5
  • 67
    • 40949141349 scopus 로고    scopus 로고
    • Prospective assessment of lymphatic dissemination in endometrial cancer: A paradigm shift in surgical staging
    • Mariani A, Dowdy SC, Cliby WA, Gostout BS, Jones MB, Wilson TO, et al. Prospective assessment of lymphatic dissemination in endometrial cancer: a paradigm shift in surgical staging. Gynecol Oncol 2008;109:11-8.
    • (2008) Gynecol Oncol , vol.109 , pp. 11-18
    • Mariani, A.1    Dowdy, S.C.2    Cliby, W.A.3    Gostout, B.S.4    Jones, M.B.5    Wilson, T.O.6
  • 68
    • 0031202077 scopus 로고    scopus 로고
    • Surgical staging of endometrial cancer: Evolution, evaluation, and responsible challenge--a personal perspective
    • Boronow RC. Surgical staging of endometrial cancer: evolution, evaluation, and responsible challenge--a personal perspective. Gynecol Oncol 1997;66:179-89.
    • (1997) Gynecol Oncol , vol.66 , pp. 179-189
    • Boronow, R.C.1
  • 70
    • 0023232969 scopus 로고
    • Surgical pathologic spread patterns of endometrial cancer: A Gynecologic Oncology Group Study
    • Creasman WT, Morrow CP, Bundy BN, Homesley HD, Graham JE, Heller PB. Surgical pathologic spread patterns of endometrial cancer: a Gynecologic Oncology Group Study. Cancer 1987;60:2035-41.
    • (1987) Cancer , vol.60 , pp. 2035-2041
    • Creasman, W.T.1    Morrow, C.P.2    Bundy, B.N.3    Homesley, H.D.4    Graham, J.E.5    Heller, P.B.6
  • 71
    • 0026060964 scopus 로고
    • Relationship between surgicalpathological risk factors and outcome in clinical stage I and II carcinoma of the endometrium: A Gynecologic Oncology Group study
    • Morrow CP, Bundy BN, Kurman RJ, Creasman WT, Heller P, Homesley HD, et al. Relationship between surgicalpathological risk factors and outcome in clinical stage I and II carcinoma of the endometrium: a Gynecologic Oncology Group study. Gynecol Oncol 1991;40:55-65.
    • (1991) Gynecol Oncol , vol.40 , pp. 55-65
    • Morrow, C.P.1    Bundy, B.N.2    Kurman, R.J.3    Creasman, W.T.4    Heller, P.5    Homesley, H.D.6
  • 72
    • 80052599644 scopus 로고    scopus 로고
    • Incidence of nodal metastasis in endometrioid endometrial cancer risk groups: A Gynecologic Oncology Groups multicenter review
    • Milan M, Java J, Walker J, Parker L, Metzinger D, Coleman R. Incidence of nodal metastasis in endometrioid endometrial cancer risk groups: a Gynecologic Oncology Groups multicenter review. Gynecol Oncol 2011;120(Suppl 1):S4.
    • (2011) Gynecol Oncol , vol.120 , Issue.SUPPL. 1
    • Milan, M.1    Java, J.2    Walker, J.3    Parker, L.4    Metzinger, D.5    Coleman, R.6
  • 73
    • 80052602950 scopus 로고    scopus 로고
    • Retrospective review of an intraoperative algorithm to predict lymph node metastasis in low-grade endometrial adenocarcinoma
    • Convery PA, Cantrell LA, Di Santo N, Broadwater G, Modesitt SC, Secord AA, et al. Retrospective review of an intraoperative algorithm to predict lymph node metastasis in low-grade endometrial adenocarcinoma. Gynecol Oncol 2011;123:65-70.
    • (2011) Gynecol Oncol , vol.123 , pp. 65-70
    • Convery, P.A.1    Cantrell, L.A.2    Di Santo, N.3    Broadwater, G.4    Modesitt, S.C.5    Secord, A.A.6
  • 74
    • 84865676566 scopus 로고    scopus 로고
    • Prospective assessment of survival, morbidity, and cost associated with lymphadenectomy in low-risk endometrial cancer
    • Dowdy SC, Borah BJ, Bakkum-Gamez JN, Weaver AL, McGree ME, Haas LR, et al. Prospective assessment of survival, morbidity, and cost associated with lymphadenectomy in low-risk endometrial cancer. Gynecol Oncol 2012;127:5-10.
    • (2012) Gynecol Oncol , vol.127 , pp. 5-10
    • Dowdy, S.C.1    Borah, B.J.2    Bakkum-Gamez, J.N.3    Weaver, A.L.4    McGree, M.E.5    Haas, L.R.6
  • 75
    • 84867182268 scopus 로고    scopus 로고
    • How low is low enough? Evaluation of various riskassessment models for lymph node metastasis in endometrial cancer: A Korean multicenter study
    • Kang S, Lee JM, Lee JK, Kim JW, Cho CH, Kim SM, et al. How low is low enough? Evaluation of various riskassessment models for lymph node metastasis in endometrial cancer: a Korean multicenter study. J Gynecol Oncol 2012;23:251-6.
    • (2012) J Gynecol Oncol , vol.23 , pp. 251-256
    • Kang, S.1    Lee, J.M.2    Lee, J.K.3    Kim, J.W.4    Cho, C.H.5    Kim, S.M.6
  • 76
    • 84862243015 scopus 로고    scopus 로고
    • Preoperative identification of a low-risk group for lymph node metastasis in endometrial cancer: A Korean gynecologic oncology group study
    • Kang S, Kang WD, Chung HH, Jeong DH, Seo SS, Lee JM, et al. Preoperative identification of a low-risk group for lymph node metastasis in endometrial cancer: a Korean gynecologic oncology group study. J Clin Oncol 2012;30:1329-34.
    • (2012) J Clin Oncol , vol.30 , pp. 1329-1334
    • Kang, S.1    Kang, W.D.2    Chung, H.H.3    Jeong, D.H.4    Seo, S.S.5    Lee, J.M.6
  • 77
    • 73949107889 scopus 로고    scopus 로고
    • Laparoscopy compared with laparotomy for comprehensive surgical staging of uterine cancer: Gynecologic Oncology Group Study LAP2
    • Walker JL, Piedmonte MR, Spirtos NM, Eisenkop SM, Schlaerth JB, Mannel RS, et al. Laparoscopy compared with laparotomy for comprehensive surgical staging of uterine cancer: Gynecologic Oncology Group Study LAP2. J Clin Oncol 2009;27:5331-6.
    • (2009) J Clin Oncol , vol.27 , pp. 5331-5336
    • Walker, J.L.1    Piedmonte, M.R.2    Spirtos, N.M.3    Eisenkop, S.M.4    Schlaerth, J.B.5    Mannel, R.S.6
  • 78
    • 84863393302 scopus 로고    scopus 로고
    • Recurrence and survival after random assignment to laparoscopy versus laparotomy for comprehensive surgical staging of uterine cancer: Gynecologic Oncology Group LAP2 Study
    • Walker JL, Piedmonte MR, Spirtos NM, Eisenkop SM, Schlaerth JB, Mannel RS, et al. Recurrence and survival after random assignment to laparoscopy versus laparotomy for comprehensive surgical staging of uterine cancer: Gynecologic Oncology Group LAP2 Study. J Clin Oncol 2012;30:695-700.
    • (2012) J Clin Oncol , vol.30 , pp. 695-700
    • Walker, J.L.1    Piedmonte, M.R.2    Spirtos, N.M.3    Eisenkop, S.M.4    Schlaerth, J.B.5    Mannel, R.S.6
  • 79
    • 84857565641 scopus 로고    scopus 로고
    • Minimally invasive surgery for endometrial cancer: The horse is already out of the barn
    • Berchuck A, Secord AA, Havrilesky LJ. Minimally invasive surgery for endometrial cancer: the horse is already out of the barn. J Clin Oncol 2012;30:681-2.
    • (2012) J Clin Oncol , vol.30 , pp. 681-682
    • Berchuck, A.1    Secord, A.A.2    Havrilesky, L.J.3
  • 80
    • 84863338301 scopus 로고    scopus 로고
    • Comparative effectiveness of robotic versus laparoscopic hysterectomy for endometrial cancer
    • Wright JD, Burke WM, Wilde ET, Lewin SN, Charles AS, Kim JH, et al. Comparative effectiveness of robotic versus laparoscopic hysterectomy for endometrial cancer. J Clin Oncol 2012;30:783-91.
    • (2012) J Clin Oncol , vol.30 , pp. 783-791
    • Wright, J.D.1    Burke, W.M.2    Wilde, E.T.3    Lewin, S.N.4    Charles, A.S.5    Kim, J.H.6
  • 81
    • 23244438005 scopus 로고    scopus 로고
    • The elevated 10-year risk of cervical precancer and cancer in women with human papillomavirus (HPV) type 16 or 18 and the possible utility of type-specific HPV testing in clinical practice
    • Khan MJ, Castle PE, Lorincz AT, Wacholder S, Sherman M, Scott DR, et al. The elevated 10-year risk of cervical precancer and cancer in women with human papillomavirus (HPV) type 16 or 18 and the possible utility of type-specific HPV testing in clinical practice. J Natl Cancer Inst 2005;97:1072-9.
    • (2005) J Natl Cancer Inst , vol.97 , pp. 1072-1079
    • Khan, M.J.1    Castle, P.E.2    Lorincz, A.T.3    Wacholder, S.4    Sherman, M.5    Scott, D.R.6
  • 82
    • 84865772757 scopus 로고    scopus 로고
    • Clinical human papillomavirus detection forecasts cervical cancer risk in women over 18 years of follow-up
    • Castle PE, Glass AG, Rush BB, Scott DR, Wentzensen N, Gage JC, et al. Clinical human papillomavirus detection forecasts cervical cancer risk in women over 18 years of follow-up. J Clin Oncol 2012;30:3044-50.
    • (2012) J Clin Oncol , vol.30 , pp. 3044-3050
    • Castle, P.E.1    Glass, A.G.2    Rush, B.B.3    Scott, D.R.4    Wentzensen, N.5    Gage, J.C.6
  • 83
    • 84870400848 scopus 로고    scopus 로고
    • A randomized, phase III trial of paclitaxel plus carboplatin (TC) versus paclitaxel plus cisplatin (TP) in stage IVb, persistent or recurrent cervical cancer: Japan Clinical Oncology Group study (JCOG 0505)
    • abstr 5006
    • Kitagawa R, Katsumata N, Shibata T, Nakanishi T, Nishimura S, Ushijima K, et al. A randomized, phase III trial of paclitaxel plus carboplatin (TC) versus paclitaxel plus cisplatin (TP) in stage IVb, persistent or recurrent cervical cancer: Japan Clinical Oncology Group study (JCOG 0505). J Clin Oncol 2012;30:abstr 5006.
    • (2012) J Clin Oncol , vol.30
    • Kitagawa, R.1    Katsumata, N.2    Shibata, T.3    Nakanishi, T.4    Nishimura, S.5    Ushijima, K.6
  • 84
    • 84869213258 scopus 로고    scopus 로고
    • Lymphatic mapping and sentinel lymph node biopsy in women with squamous cell carcinoma of the vulva: A gynecologic oncology group study
    • Levenback CF, Ali S, Coleman RL, Gold MA, Fowler JM, Judson PL, et al. Lymphatic mapping and sentinel lymph node biopsy in women with squamous cell carcinoma of the vulva: a gynecologic oncology group study. J Clin Oncol 2012;30:3786-91.
    • (2012) J Clin Oncol , vol.30 , pp. 3786-3791
    • Levenback, C.F.1    Ali, S.2    Coleman, R.L.3    Gold, M.A.4    Fowler, J.M.5    Judson, P.L.6
  • 85
    • 0034761028 scopus 로고    scopus 로고
    • Intraoperative lymphatic mapping and sentinel node identification with blue dye in patients with vulvar cancer
    • Levenback C, Coleman RL, Burke TW, Bodurka-Bevers D, Wolf JK, Gershenson DM. Intraoperative lymphatic mapping and sentinel node identification with blue dye in patients with vulvar cancer. Gynecol Oncol 2001;83:276-81.
    • (2001) Gynecol Oncol , vol.83 , pp. 276-281
    • Levenback, C.1    Coleman, R.L.2    Burke, T.W.3    Bodurka-Bevers, D.4    Wolf, J.K.5    Gershenson, D.M.6
  • 86
    • 33846785512 scopus 로고    scopus 로고
    • Further data on sentinel lymph node mapping in vulvar cancer by blue dye and radiocolloid Tc99
    • Rob L, Robova H, Pluta M, Strnad P, Kacirek J, Skapa P, et al. Further data on sentinel lymph node mapping in vulvar cancer by blue dye and radiocolloid Tc99. Int J Gynecol Cancer 2007;17:147-53.
    • (2007) Int J Gynecol Cancer , vol.17 , pp. 147-153
    • Rob, L.1    Robova, H.2    Pluta, M.3    Strnad, P.4    Kacirek, J.5    Skapa, P.6
  • 90
    • 20044389263 scopus 로고    scopus 로고
    • Recommendations from Gynaecological (GYN) GEC-ESTRO Working Group (I): Concepts and terms in 3D image based 3D treatment planning in cervix cancer brachytherapy with emphasis on MRI assessment of GTV and CTV
    • Haie-Meder C, Potter R, Van Limbergen E, Briot E, De Brabandere M, Dimopoulos J, et al. Recommendations from Gynaecological (GYN) GEC-ESTRO Working Group (I): concepts and terms in 3D image based 3D treatment planning in cervix cancer brachytherapy with emphasis on MRI assessment of GTV and CTV. Radiother Oncol 2005;74:235-45.
    • (2005) Radiother Oncol , vol.74 , pp. 235-245
    • Haie-Meder, C.1    Potter, R.2    van Limbergen, E.3    Briot, E.4    de Brabandere, M.5    Dimopoulos, J.6
  • 91
    • 31144452943 scopus 로고    scopus 로고
    • Recommendations from gynaecological (GYN) GEC ESTRO working group (II): Concepts and terms in 3D image-based treatment planning in cervix cancer brachytherapy-3D dose volume parameters and aspects of 3D image-based anatomy, radiation physics, radiobiology
    • Potter R, Haie-Meder C, Van Limbergen E, Barillot I, De Brabandere M, Dimopoulos J, et al. Recommendations from gynaecological (GYN) GEC ESTRO working group (II): concepts and terms in 3D image-based treatment planning in cervix cancer brachytherapy-3D dose volume parameters and aspects of 3D image-based anatomy, radiation physics, radiobiology. Radiother Oncol 2006;78:67-77.
    • (2006) Radiother Oncol , vol.78 , pp. 67-77
    • Potter, R.1    Haie-Meder, C.2    van Limbergen, E.3    Barillot, I.4    de Brabandere, M.5    Dimopoulos, J.6
  • 94
    • 80055120113 scopus 로고    scopus 로고
    • Implementation of image-guided brachytherapy for cervix cancer in the UK: Progress update
    • Tan LT. Implementation of image-guided brachytherapy for cervix cancer in the UK: progress update. Clin Oncol (R Coll Radiol) 2011;23:681-4.
    • (2011) Clin Oncol (R Coll Radiol) , vol.23 , pp. 681-684
    • Tan, L.T.1
  • 95
    • 67651087466 scopus 로고    scopus 로고
    • Comparative study of LDR (Manchester system) and HDR image-guided conformal brachytherapy of cervical cancer: Patterns of failure, late complications, and survival
    • Narayan K, van Dyk S, Bernshaw D, Rajasooriyar C, Kondalsamy-Chennakesavan S. Comparative study of LDR (Manchester system) and HDR image-guided conformal brachytherapy of cervical cancer: patterns of failure, late complications, and survival. Int J Radiat Oncol Biol Phys 2009;74:1529-35.
    • (2009) Int J Radiat Oncol Biol Phys , vol.74 , pp. 1529-1535
    • Narayan, K.1    van Dyk, S.2    Bernshaw, D.3    Rajasooriyar, C.4    Kondalsamy-Chennakesavan, S.5
  • 96
    • 29244465064 scopus 로고    scopus 로고
    • CT-guided intracavitary radiotherapy for cervical cancer: Comparison of conventional point A plan with clinical target volume-based three-dimensional plan using dose-volume parameters
    • Shin KH, Kim TH, Cho JK, Kim JY, Park SY, Kim DY, et al. CT-guided intracavitary radiotherapy for cervical cancer: Comparison of conventional point A plan with clinical target volume-based three-dimensional plan using dose-volume parameters. Int J Radiat Oncol Biol Phys 2006;64:197-204.
    • (2006) Int J Radiat Oncol Biol Phys , vol.64 , pp. 197-204
    • Shin, K.H.1    Kim, T.H.2    Cho, J.K.3    Kim, J.Y.4    Park, S.Y.5    Kim, D.Y.6
  • 97
    • 84861807198 scopus 로고    scopus 로고
    • Impact of 3D image-based PDR brachytherapy on outcome of patients treated for cervix carcinoma in France: Results of the French STIC prospective study
    • Charra-Brunaud C, Harter V, Delannes M, Haie-Meder C, Quetin P, Kerr C, et al. Impact of 3D image-based PDR brachytherapy on outcome of patients treated for cervix carcinoma in France: results of the French STIC prospective study. Radiother Oncol 2012;103:305-13.
    • (2012) Radiother Oncol , vol.103 , pp. 305-313
    • Charra-Brunaud, C.1    Harter, V.2    Delannes, M.3    Haie-Meder, C.4    Quetin, P.5    Kerr, C.6
  • 98
    • 84870517100 scopus 로고    scopus 로고
    • A review of recent developments in image-guided radiation therapy in cervix cancer
    • Sadozye AH, Reed N. A review of recent developments in image-guided radiation therapy in cervix cancer. Curr Oncol Rep 2012;14:519-26.
    • (2012) Curr Oncol Rep , vol.14 , pp. 519-526
    • Sadozye, A.H.1    Reed, N.2
  • 99
    • 34247844654 scopus 로고    scopus 로고
    • Computed tomography versus magnetic resonance imaging-based contouring in cervical cancer brachytherapy: Results of a prospective trial and preliminary guidelines for standardized contours
    • Viswanathan AN, Dimopoulos J, Kirisits C, Berger D, Potter R. Computed tomography versus magnetic resonance imaging-based contouring in cervical cancer brachytherapy: results of a prospective trial and preliminary guidelines for standardized contours. Int J Radiat Oncol Biol Phys 2007;68:491-8.
    • (2007) Int J Radiat Oncol Biol Phys , vol.68 , pp. 491-498
    • Viswanathan, A.N.1    Dimopoulos, J.2    Kirisits, C.3    Berger, D.4    Potter, R.5
  • 100
    • 80051789536 scopus 로고    scopus 로고
    • Clinical outcome of protocol based image (MRI) guided adaptive brachytherapy combined with 3D conformal radiotherapy with or without chemotherapy in patients with locally advanced cervical cancer
    • Potter R, Georg P, Dimopoulos JC, Grimm M, Berger D, Nesvacil N, et al. Clinical outcome of protocol based image (MRI) guided adaptive brachytherapy combined with 3D conformal radiotherapy with or without chemotherapy in patients with locally advanced cervical cancer. Radiother Oncol 2011;100:116-23.
    • (2011) Radiother Oncol , vol.100 , pp. 116-123
    • Potter, R.1    Georg, P.2    Dimopoulos, J.C.3    Grimm, M.4    Berger, D.5    Nesvacil, N.6
  • 101
    • 34249672864 scopus 로고    scopus 로고
    • Trastuzumab: Triumphs and tribulations
    • Nahta R, Esteva FJ. Trastuzumab: triumphs and tribulations. Oncogene 2007;26:3637-43.
    • (2007) Oncogene , vol.26 , pp. 3637-3643
    • Nahta, R.1    Esteva, F.J.2
  • 102
    • 84862914692 scopus 로고    scopus 로고
    • Pertuzumab plus trastuzumab plus docetaxel for metastatic breast cancer
    • Baselga J, Cortes J, Kim SB, Im SA, Hegg R, Im YH, et al. Pertuzumab plus trastuzumab plus docetaxel for metastatic breast cancer. N Engl J Med 2012;366:109-19.
    • (2012) N Engl J Med , vol.366 , pp. 109-119
    • Baselga, J.1    Cortes, J.2    Kim, S.B.3    Im, S.A.4    Hegg, R.5    Im, Y.H.6
  • 103
    • 67649472398 scopus 로고    scopus 로고
    • Novel anticancer targets: Revisiting ERBB2 and discovering ERBB3
    • Baselga J, Swain SM. Novel anticancer targets: revisiting ERBB2 and discovering ERBB3. Nat Rev Cancer 2009;9:463-75.
    • (2009) Nat Rev Cancer , vol.9 , pp. 463-475
    • Baselga, J.1    Swain, S.M.2
  • 105
    • 73649149433 scopus 로고    scopus 로고
    • Strongly enhanced antitumor activity of trastuzumab and pertuzumab combination treatment on HER2-positive human xenograft tumor models
    • Scheuer W, Friess T, Burtscher H, Bossenmaier B, Endl J, Hasmann M. Strongly enhanced antitumor activity of trastuzumab and pertuzumab combination treatment on HER2-positive human xenograft tumor models. Cancer Res 2009;69:9330-6.
    • (2009) Cancer Res , vol.69 , pp. 9330-9336
    • Scheuer, W.1    Friess, T.2    Burtscher, H.3    Bossenmaier, B.4    Endl, J.5    Hasmann, M.6
  • 108
    • 32944466881 scopus 로고    scopus 로고
    • Clinical efforts to combine endocrine agents with targeted therapies against epidermal growth factor receptor/human epidermal growth factor receptor 2 and mammalian target of rapamycin in breast cancer
    • Johnston SR. Clinical efforts to combine endocrine agents with targeted therapies against epidermal growth factor receptor/human epidermal growth factor receptor 2 and mammalian target of rapamycin in breast cancer. Clin Cancer Res 2006;12:1061s-1068s.
    • (2006) Clin Cancer Res , vol.12
    • Johnston, S.R.1
  • 109
    • 65249190250 scopus 로고    scopus 로고
    • S6 kinase 1 regulates estrogen receptor alpha in control of breast cancer cell proliferation
    • Yamnik RL, Digilova A, Davis DC, Brodt ZN, Murphy CJ, Holz MK. S6 kinase 1 regulates estrogen receptor alpha in control of breast cancer cell proliferation. J Biol Chem 2009;284:6361-9.
    • (2009) J Biol Chem , vol.284 , pp. 6361-6369
    • Yamnik, R.L.1    Digilova, A.2    Davis, D.C.3    Brodt, Z.N.4    Murphy, C.J.5    Holz, M.K.6
  • 110
    • 22344446415 scopus 로고    scopus 로고
    • Dual inhibition of mTOR and estrogen receptor signaling in vitro induces cell death in models of breast cancer
    • Boulay A, Rudloff J, Ye J, Zumstein-Mecker S, O'Reilly T, Evans DB, et al. Dual inhibition of mTOR and estrogen receptor signaling in vitro induces cell death in models of breast cancer. Clin Cancer Res 2005;11:5319-28.
    • (2005) Clin Cancer Res , vol.11 , pp. 5319-5328
    • Boulay, A.1    Rudloff, J.2    Ye, J.3    Zumstein-Mecker, S.4    O'Reilly, T.5    Evans, D.B.6
  • 111
    • 66849136781 scopus 로고    scopus 로고
    • Phase II randomized study of neoadjuvant everolimus plus letrozole compared with placebo plus letrozole in patients with estrogen receptor-positive breast cancer
    • Baselga J, Semiglazov V, van Dam P, Manikhas A, Bellet M, Mayordomo J, et al. Phase II randomized study of neoadjuvant everolimus plus letrozole compared with placebo plus letrozole in patients with estrogen receptor-positive breast cancer. J Clin Oncol 2009;27:2630-7.
    • (2009) J Clin Oncol , vol.27 , pp. 2630-2637
    • Baselga, J.1    Semiglazov, V.2    van Dam, P.3    Manikhas, A.4    Bellet, M.5    Mayordomo, J.6
  • 112
    • 37549072095 scopus 로고    scopus 로고
    • National Comprehensive Cancer Network, Fort Washington, PA: National Comprehensive Cancer Network, [cited 2012 Dec 25]. Available from:
    • National Comprehensive Cancer Network. NCCN clinical practice guidelines in oncology [Internet]. Fort Washington, PA: National Comprehensive Cancer Network; 2012 [cited 2012 Dec 25]. Available from: http:// www.nccn.org/professionals/physician_gls/f_guidelines. asp.
    • (2012) NCCN clinical practice guidelines in oncology [Internet]
  • 113
    • 84860818533 scopus 로고    scopus 로고
    • American Cancer Society, American Society for Colposcopy and Cervical Pathology, and American Society for Clinical Pathology screening guidelines for the prevention and early detection of cervical cancer
    • Saslow D, Solomon D, Lawson HW, Killackey M, Kulasingam SL, Cain J, et al. American Cancer Society, American Society for Colposcopy and Cervical Pathology, and American Society for Clinical Pathology screening guidelines for the prevention and early detection of cervical cancer. CA Cancer J Clin 2012;62:147-72.
    • (2012) CA Cancer J Clin , vol.62 , pp. 147-172
    • Saslow, D.1    Solomon, D.2    Lawson, H.W.3    Killackey, M.4    Kulasingam, S.L.5    Cain, J.6
  • 114
    • 84873046955 scopus 로고    scopus 로고
    • American College of Obstetricians and Gynecologists (ACOG), Washington, DC: ACOG, [cited 2012 Dec 25]. Available from:
    • American College of Obstetricians and Gynecologists (ACOG). Management of gynecologic issues in women with breast cancer [Internet]. Washington, DC: ACOG; 2012 [cited 2012 Dec 25]. Available from: http://www. guideline.gov/content.aspx?id=36055&search=gynecol ogic+issues+in+women+with+breast+cancer.
    • (2012) Management of gynecologic issues in women with breast cancer [Internet]


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.