Induction of death of leukemia cells by tw-74, a novel derivative of chloro-naphthoquinone

Anticancer Research

Volumn 33, Issue 1, 2013, Pages 183-190

  Hallak, Maher ^a,b   Thakur, Basant K ^c   Winn, Thida ^d   Shpilberg, Ofer ^e   Bittner, Shmuel ^a   Granot, Yosef ^a   Levy, Itai ^a   Nathan, Ilana ^a,b  

^a BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

^b BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

^c HANNOVER MEDICAL SCHOOL   (Germany)

^d Kyaukse University   (Myanmar)

^e RABIN MEDICAL CENTER   (Israel)

Author keywords

Apoptosis; BCL2; Chronic lymphocytic leukemia (CLL); Cytochrome C; MAPKs; Mitochondria; Naphthoquinones

Indexed keywords

CASPASE; CYTOCHROME C; NAPHTHOQUINONE; PROTEIN BCL 2; TW 74; UNCLASSIFIED DRUG;

ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG STRUCTURE; ENZYME ACTIVATION; HUMAN; HUMAN CELL; LEUKEMIA CELL; LIVER MITOCHONDRION; MITOCHONDRIAL MEMBRANE POTENTIAL; MYELOID LEUKEMIA; NONHUMAN; PRIORITY JOURNAL; PROTEIN SECRETION; RAT; RECEPTOR DOWN REGULATION; SWELLING;

ANIMALS; APOPTOSIS; CASPASES; CYTOCHROMES C; HL-60 CELLS; HUMANS; LEUKEMIA, MYELOID, ACUTE; MITOCHONDRIA, LIVER; MITOGEN-ACTIVATED PROTEIN KINASES; NAPHTHOQUINONES; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; STRUCTURE-ACTIVITY RELATIONSHIP; U937 CELLS;

EID: 84873027018     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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