Genotype instability during long-term subculture of lymphoblastoid cell lines

Journal of Human Genetics

Volumn 58, Issue 1, 2013, Pages 16-20

  Oh, Ji Hee ^a,c   Kim, Young Jin ^a,d   Moon, Sanghoon ^a   Nam, Hye Young ^b   Jeon, Jae Pil ^b   Ho Lee, Jong ^c   Lee, Jong Young ^a   Cho, Yoon Shin ^a,e  

^a Korea National Institute of Health   (South Korea)

^b National Biobank of Korea   (South Korea)

^c Yonsei University   (South Korea)

^d Seoul National University   (South Korea)

^e Hallym University   (South Korea)

Author keywords

Genome wide association study; Lymphoblastoid cell line; Single nucleotide polymorphism

Indexed keywords

GENOMIC DNA;

ADULT; AGED; ARTICLE; CELL COUNT; CELL CULTURE; CELL IMMORTALIZATION; CULTURE MEDIUM; EPSTEIN BARR VIRUS; GENE FREQUENCY; GENETIC ANALYSIS; GENOMIC INSTABILITY; GENOTYPE; HETEROZYGOSITY LOSS; HUMAN; HUMAN CELL; LYMPHOID CELL LINE; PERIPHERAL BLOOD MONONUCLEAR CELL; VIRUS DNA CELL DNA INTERACTION;

ADULT; AGED; CELL LINE, TRANSFORMED; CELL TRANSFORMATION, VIRAL; CELLS, CULTURED; GENETIC VARIATION; GENOTYPE; HERPESVIRUS 4, HUMAN; HUMANS; LEUKOCYTES, MONONUCLEAR; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; VIRUS INTEGRATION;

EID: 84873020917     PISSN: 14345161     EISSN: 1435232X     Source Type: Journal    
DOI: 10.1038/jhg.2012.123     Document Type: Article

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