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Volumn 78, Issue 3, 2013, Pages 330-337

The role of obesity and type 2 diabetes mellitus in the development of male obesity-associated secondary hypogonadism

Author keywords

[No Author keywords available]

Indexed keywords

LUTEINIZING HORMONE; TESTOSTERONE;

EID: 84872961206     PISSN: 03000664     EISSN: 13652265     Source Type: Journal    
DOI: 10.1111/cen.12092     Document Type: Review
Times cited : (115)

References (66)
  • 3
    • 67650233470 scopus 로고    scopus 로고
    • Lower testosterone levels predict incident stroke and transient ischemic attack in older men
    • Yeap, B.B., Hyde, Z., Almeida, O.P., et al,. (2009) Lower testosterone levels predict incident stroke and transient ischemic attack in older men. The Journal of Clinical Endocrinology and Metabolism, 94, 2353-2359.
    • (2009) The Journal of Clinical Endocrinology and Metabolism , vol.94 , pp. 2353-2359
    • Yeap, B.B.1    Hyde, Z.2    Almeida, O.P.3
  • 4
    • 77956616664 scopus 로고    scopus 로고
    • Gonadal and adrenal androgen deficiencies as independent predictors of increased cardiovascular mortality in men with type II diabetes mellitus and stable coronary artery disease
    • Ponikowska, B., Jankowska, E.A., Maj, J., et al,. (2010) Gonadal and adrenal androgen deficiencies as independent predictors of increased cardiovascular mortality in men with type II diabetes mellitus and stable coronary artery disease. International Journal of Cardiology, 143, 343-348.
    • (2010) International Journal of Cardiology , vol.143 , pp. 343-348
    • Ponikowska, B.1    Jankowska, E.A.2    Maj, J.3
  • 5
    • 84855568280 scopus 로고    scopus 로고
    • Androgens and adipose tissue in males: A complex and reciprocal interplay
    • Mammi, C., Calanchini, M., Antelmi, A., et al,. (2012) Androgens and adipose tissue in males: a complex and reciprocal interplay. International Journal of Endocrinology, 2012, 789653.
    • (2012) International Journal of Endocrinology , vol.2012 , pp. 789653
    • Mammi, C.1    Calanchini, M.2    Antelmi, A.3
  • 7
    • 0033055409 scopus 로고    scopus 로고
    • The hypogonadal-obesity cycle: Role of aromatase in modulating the testosterone-estradiol shunt-A major factor in the genesis of morbid obesity
    • Cohen, P.G., (1999) The hypogonadal-obesity cycle: role of aromatase in modulating the testosterone-estradiol shunt-a major factor in the genesis of morbid obesity. Medical Hypotheses, 52, 49-51.
    • (1999) Medical Hypotheses , vol.52 , pp. 49-51
    • Cohen, P.G.1
  • 8
    • 24144493455 scopus 로고    scopus 로고
    • Androgens, insulin resistance and vascular disease in men
    • DOI 10.1111/j.1365-2265.2005.02299.x
    • Kapoor, D., Malkin, C.J., Channer, K.S., et al,. (2005) Androgens, insulin resistance and vascular disease in men. Clinical Endocrinology, 63, 239-250. (Pubitemid 41233438)
    • (2005) Clinical Endocrinology , vol.63 , Issue.3 , pp. 239-250
    • Kapoor, D.1    Malkin, C.J.2    Channer, K.S.3    Jones, T.H.4
  • 10
    • 33746324557 scopus 로고    scopus 로고
    • Contrasting testosterone concentrations in type 1 and type 2 diabetes
    • DOI 10.2337/diacare.2951120
    • Tomar, R., Dhindsa, S., Chaudhuri, A., et al,. (2006) Contrasting testosterone concentrations in type 1 and type 2 diabetes. Diabetes Care, 29, 1120-1122. (Pubitemid 44115257)
    • (2006) Diabetes Care , vol.29 , Issue.5 , pp. 1120-1122
    • Tomar, R.1    Dhindsa, S.2    Chaudhuri, A.3    Mohanty, P.4    Garg, R.5    Dandona, P.6
  • 11
    • 77954394453 scopus 로고    scopus 로고
    • Clinical review 1: Adverse effects of testosterone therapy in adult men: A systematic review and meta-analysis
    • Fernandez-Balsells, M.M., Murad, M.H., Lane, M., et al,. (2010) Clinical review 1: adverse effects of testosterone therapy in adult men: a systematic review and meta-analysis. The Journal of Clinical Endocrinology and Metabolism, 95, 2560-2575.
    • (2010) The Journal of Clinical Endocrinology and Metabolism , vol.95 , pp. 2560-2575
    • Fernandez-Balsells, M.M.1    Murad, M.H.2    Lane, M.3
  • 12
    • 68949172537 scopus 로고    scopus 로고
    • Effect of long-acting testosterone treatment on functional exercise capacity, skeletal muscle performance, insulin resistance, and baroreflex sensitivity in elderly patients with chronic heart failure a double-blind, placebo-controlled, randomized study
    • Caminiti, G., Volterrani, M., Iellamo, F., et al,. (2009) Effect of long-acting testosterone treatment on functional exercise capacity, skeletal muscle performance, insulin resistance, and baroreflex sensitivity in elderly patients with chronic heart failure a double-blind, placebo-controlled, randomized study. Journal of the American College of Cardiology, 54, 919-927.
    • (2009) Journal of the American College of Cardiology , vol.54 , pp. 919-927
    • Caminiti, G.1    Volterrani, M.2    Iellamo, F.3
  • 14
    • 79956271879 scopus 로고    scopus 로고
    • Testosterone replacement in hypogonadal men with type 2 diabetes and/or metabolic syndrome (the TIMES2 study)
    • Jones, T.H., Arver, S., Behre, H.M., et al,. (2011) Testosterone replacement in hypogonadal men with type 2 diabetes and/or metabolic syndrome (the TIMES2 study). Diabetes Care, 34, 828-837.
    • (2011) Diabetes Care , vol.34 , pp. 828-837
    • Jones, T.H.1    Arver, S.2    Behre, H.M.3
  • 15
    • 78449294931 scopus 로고    scopus 로고
    • Effects of testosterone supplementation on markers of the metabolic syndrome and inflammation in hypogonadal men with the metabolic syndrome: The double-blinded placebo-controlled Moscow study
    • Kalinchenko, S.Y., Tishova, Y.A., Mskhalaya, G.J., et al,. (2010) Effects of testosterone supplementation on markers of the metabolic syndrome and inflammation in hypogonadal men with the metabolic syndrome: the double-blinded placebo-controlled Moscow study. Clinical Endocrinology (Oxford), 73, 602-612.
    • (2010) Clinical Endocrinology (Oxford) , vol.73 , pp. 602-612
    • Kalinchenko, S.Y.1    Tishova, Y.A.2    Mskhalaya, G.J.3
  • 16
    • 79953765663 scopus 로고    scopus 로고
    • Associations of endogenous testosterone and SHBG with glycated haemoglobin in middle-aged and older men
    • Brand, J.S., Wareham, N.J., Dowsett, M., et al,. (2011) Associations of endogenous testosterone and SHBG with glycated haemoglobin in middle-aged and older men. Clinical Endocrinology, 74, 572-578.
    • (2011) Clinical Endocrinology , vol.74 , pp. 572-578
    • Brand, J.S.1    Wareham, N.J.2    Dowsett, M.3
  • 17
    • 0242636831 scopus 로고    scopus 로고
    • Hypothalamic Interleukin-1β and Tumor Necrosis Factor-α, but Not Interleukin-6, Mediate the Endotoxin-Induced Suppression of the Reproductive Axis in Rats
    • DOI 10.1210/en.2003-0644
    • Watanobe, H., &, Hayakawa, Y., (2003) Hypothalamic interleukin-1 beta and tumor necrosis factor-alpha, but not interleukin-6, mediate the endotoxin-induced suppression of the reproductive axis in rats. Endocrinology, 144, 4868-4875. (Pubitemid 37378401)
    • (2003) Endocrinology , vol.144 , Issue.11 , pp. 4868-4875
    • Watanobe, H.1    Hayakawa, Y.2
  • 18
    • 0348222671 scopus 로고    scopus 로고
    • Inflammation: The link between insulin resistance, obesity and diabetes
    • DOI 10.1016/j.it.2003.10.013
    • Dandona, P., Aljada, A., &, Bandyopadhyay, A., (2004) Inflammation: the link between insulin resistance, obesity and diabetes. Trends in Immunology, 25, 4-7. (Pubitemid 38032801)
    • (2004) Trends in Immunology , vol.25 , Issue.1 , pp. 4-7
    • Dandona, P.1    Aljada, A.2    Bandyopadhyay, A.3
  • 19
    • 34249103249 scopus 로고    scopus 로고
    • The effect of testosterone replacement theraphy on adipocytokines and C-reactive protein in hypogonadal men with type 2 diabetes
    • DOI 10.1530/EJE-06-0737
    • Kapoor, D, Clarke, S., Stanworth, R., et al,. (2007) The effect of testosterone replacement therapy on adipocytokines and C-reactive protein in hypogonadal men with type 2 diabetes. European Journal of Endocrinology/European Federation of Endocrine Societies, 156, 595-602. (Pubitemid 46796527)
    • (2007) European Journal of Endocrinology , vol.156 , Issue.5 , pp. 595-602
    • Kapoor, D.1    Clarke, S.2    Stanworth, R.3    Channer, K.S.4    Jones, T.H.5
  • 20
    • 84855428534 scopus 로고    scopus 로고
    • Updates on the relation of weight excess and reproductive function in men: Sleep apnea as a new area of interest
    • Hammoud, A.O., Carrell, D.T., Gibson, M., et al,. (2012) Updates on the relation of weight excess and reproductive function in men: sleep apnea as a new area of interest. Asian Journal of Andrology, 14, 77-81.
    • (2012) Asian Journal of Andrology , vol.14 , pp. 77-81
    • Hammoud, A.O.1    Carrell, D.T.2    Gibson, M.3
  • 21
    • 79960848642 scopus 로고    scopus 로고
    • The role of testosterone in the etiology and treatment of obesity, the metabolic syndrome, and diabetes mellitus type 2
    • Saad, F., &, Gooren, L.J., (2011) The role of testosterone in the etiology and treatment of obesity, the metabolic syndrome, and diabetes mellitus type 2. Journal of Obesity 2011, 2011.
    • (2011) Journal of Obesity , vol.2011 , pp. 2011
    • Saad, F.1    Gooren, L.J.2
  • 22
    • 77956070954 scopus 로고    scopus 로고
    • Testosterone concentrations in diabetic and nondiabetic obese men
    • Dhindsa, S., Miller, M.G., McWhirter, C.L., et al,. (2010) Testosterone concentrations in diabetic and nondiabetic obese men. Diabetes Care, 33, 1186-1192.
    • (2010) Diabetes Care , vol.33 , pp. 1186-1192
    • Dhindsa, S.1    Miller, M.G.2    McWhirter, C.L.3
  • 23
    • 74049148850 scopus 로고    scopus 로고
    • Recent dynamics suggest selected countries catching up to US obesity
    • Popkin, B.M., (2010) Recent dynamics suggest selected countries catching up to US obesity. The American Journal of Clinical Nutrition, 91, 284S-288S.
    • (2010) The American Journal of Clinical Nutrition , vol.91
    • Popkin, B.M.1
  • 24
    • 33644780661 scopus 로고    scopus 로고
    • Male hypogonadism. Part I: Epidemiology of hypogonadism
    • DOI 10.1038/sj.ijir.3901397, PII 3901397
    • Seftel, A.D., (2006) Male hypogonadism. Part I: epidemiology of hypogonadism. International Journal of Impotence Research, 18, 115-120. (Pubitemid 43336474)
    • (2006) International Journal of Impotence Research , vol.18 , Issue.2 , pp. 115-120
    • Seftel, A.D.1
  • 25
    • 33646573358 scopus 로고    scopus 로고
    • Male hypogonadism. Part II: Etiology, pathophysiology, and diagnosis
    • Seftel, A., (2006) Male hypogonadism. Part II: etiology, pathophysiology, and diagnosis. International Journal of Impotence Research, 18, 223-228.
    • (2006) International Journal of Impotence Research , vol.18 , pp. 223-228
    • Seftel, A.1
  • 26
    • 80051560339 scopus 로고    scopus 로고
    • Reference ranges for testosterone in men generated using liquid chromatography tandem mass spectrometry in a community-based sample of healthy nonobese young men in the Framingham Heart Study and applied to three geographically distinct cohorts
    • Bhasin, S., Pencina, M., Jasuja, G.K., et al,. (2011) Reference ranges for testosterone in men generated using liquid chromatography tandem mass spectrometry in a community-based sample of healthy nonobese young men in the Framingham Heart Study and applied to three geographically distinct cohorts. The Journal of Clinical Endocrinology and Metabolism, 96, 2430-2439.
    • (2011) The Journal of Clinical Endocrinology and Metabolism , vol.96 , pp. 2430-2439
    • Bhasin, S.1    Pencina, M.2    Jasuja, G.K.3
  • 27
    • 77954414397 scopus 로고    scopus 로고
    • Identification of late-onset hypogonadism in middle-aged and elderly men
    • Wu, FC., Tajar, A., Beynon, J.M., et al,. (2010) Identification of late-onset hypogonadism in middle-aged and elderly men. The New England Journal of Medicine, 363, 123-135.
    • (2010) The New England Journal of Medicine , vol.363 , pp. 123-135
    • Wu, F.C.1    Tajar, A.2    Beynon, J.M.3
  • 28
    • 62149150656 scopus 로고    scopus 로고
    • Interlaboratory comparison study of serum total testosterone [corrected] measurements performed by mass spectrometry methods
    • Vesper, H.W., Bhasin, S., Wang, C., et al,. (2009) Interlaboratory comparison study of serum total testosterone [corrected] measurements performed by mass spectrometry methods. Steroids, 74, 498-503.
    • (2009) Steroids , vol.74 , pp. 498-503
    • Vesper, H.W.1    Bhasin, S.2    Wang, C.3
  • 30
    • 84862885980 scopus 로고    scopus 로고
    • European association of urology guidelines on male infertility: The 2012 update
    • Jungwirth, A., Giwercman, A., Tournaye, H., et al,. (2012) European association of urology guidelines on male infertility: the 2012 update. European Urology, 62, 324-332.
    • (2012) European Urology , vol.62 , pp. 324-332
    • Jungwirth, A.1    Giwercman, A.2    Tournaye, H.3
  • 31
    • 77952970891 scopus 로고    scopus 로고
    • Complex genetics in idiopathic hypogonadotropic hypogonadism
    • Pitteloud, N., Durrani, S., Raivio, T., et al,. (2010) Complex genetics in idiopathic hypogonadotropic hypogonadism. Frontiers of Hormone Research, 39, 142-153.
    • (2010) Frontiers of Hormone Research , vol.39 , pp. 142-153
    • Pitteloud, N.1    Durrani, S.2    Raivio, T.3
  • 32
    • 77954409942 scopus 로고    scopus 로고
    • Testosterone therapy in men with androgen deficiency syndromes: An Endocrine Society clinical practice guideline
    • Bhasin, S., Cunningham, GR., Hayes, FJ., et al,. (2010) Testosterone therapy in men with androgen deficiency syndromes: an Endocrine Society clinical practice guideline. The Journal of Clinical Endocrinology and Metabolism, 95, 2536-2559.
    • (2010) The Journal of Clinical Endocrinology and Metabolism , vol.95 , pp. 2536-2559
    • Bhasin, S.1    Cunningham, G.R.2    Hayes, F.J.3
  • 33
    • 34147104552 scopus 로고    scopus 로고
    • Clinical and biochemical assessment of hypogonadism in men with type 2 diabetes: Correlations with bioavailable testosterone and visceral adiposity
    • DOI 10.2337/dc06-1426
    • Kapoor, D., Aldred, H., Clark, S., et al,. (2007) Clinical and biochemical assessment of hypogonadism in men with type 2 diabetes: correlations with bioavailable testosterone and visceral adiposity. Diabetes Care, 30, 911-917. (Pubitemid 46556586)
    • (2007) Diabetes Care , vol.30 , Issue.4 , pp. 911-917
    • Kapoor, D.1    Aldred, H.2    Clark, S.3    Channer, K.S.4    Jones, T.H.5
  • 35
    • 47549111535 scopus 로고    scopus 로고
    • The relative role of gonadal sex steroids and gonadotropin-releasing hormone pulse frequency in the regulation of follicle-stimulating hormone secretion in men
    • DOI 10.1210/jc.2007-2548
    • Pitteloud, N., Dwyer, A.A., DeCruz, S., et al,. (2008) The relative role of gonadal sex steroids and gonadotropin-releasing hormone pulse frequency in the regulation of follicle-stimulating hormone secretion in men. The Journal of Clinical Endocrinology and Metabolism, 93, 2686-2692. (Pubitemid 352008537)
    • (2008) Journal of Clinical Endocrinology and Metabolism , vol.93 , Issue.7 , pp. 2686-2692
    • Pitteloud, N.1    Dwyer, A.A.2    DeCruz, S.3    Lee, H.4    Boepple, P.A.5    Crowley Jr., W.F.6    Hayes, F.J.7
  • 36
    • 43149085965 scopus 로고    scopus 로고
    • Letrozole once a week normalizes serum testosterone in obesity-related male hypogonadism
    • DOI 10.1530/EJE-07-0663
    • Loves, S., Ruinemans-Koerts, J., &, de Boer, H., (2008) Letrozole once a week normalizes serum testosterone in obesity-related male hypogonadism. European Journal of Endocrinology/European Federation of Endocrine Societies, 158, 741-747. (Pubitemid 351639613)
    • (2008) European Journal of Endocrinology , vol.158 , Issue.5 , pp. 741-747
    • Loves, S.1    Ruinemans-Koerts, J.2    De Boer, H.3
  • 39
    • 0141570989 scopus 로고    scopus 로고
    • Reversal of the hypogonadotropic hypogonadism of obese men by administration of the aromatase inhibitor testolactone
    • DOI 10.1016/S0026-0495(03)00186-0
    • Zumoff, B., Miller, L.K., &, Strain, G.W., (2003) Reversal of the hypogonadotropic hypogonadism of obese men by administration of the aromatase inhibitor testolactone. Metabolism: Clinical and Experimental, 52, 1126-1128. (Pubitemid 37203485)
    • (2003) Metabolism: Clinical and Experimental , vol.52 , Issue.9 , pp. 1126-1128
    • Zumoff, B.1    Miller, L.K.2    Strain, G.W.3
  • 40
    • 59249097381 scopus 로고    scopus 로고
    • Hypogonadotrophic hypogonadism in type 2 diabetes, obesity and the metabolic syndrome
    • Dandona, P., Dhindsa, S., Chaudhuri, A., et al,. (2008) Hypogonadotrophic hypogonadism in type 2 diabetes, obesity and the metabolic syndrome. Current Molecular Medicine 8, 816-828.
    • (2008) Current Molecular Medicine , vol.8 , pp. 816-828
    • Dandona, P.1    Dhindsa, S.2    Chaudhuri, A.3
  • 42
    • 33745976149 scopus 로고    scopus 로고
    • Control of GnRH neuronal activity by metabolic factors: The role of leptin and insulin
    • DOI 10.1016/j.mce.2006.04.023, PII S0303720706002255
    • Gamba, M., &, Pralong, FP., (2006) Control of GnRH neuronal activity by metabolic factors: the role of leptin and insulin. Molecular and Cellular Endocrinology 254-255, 133-139. (Pubitemid 44063601)
    • (2006) Molecular and Cellular Endocrinology , vol.254-255 , pp. 133-139
    • Gamba, M.1    Pralong, F.P.2
  • 43
    • 32144439859 scopus 로고    scopus 로고
    • Altered luteinizing hormone and testosterone secretion in middle-aged obese men with obstructive sleep apnea
    • Luboshitzky, R., Lavie, L., Shen-Orr, Z., et al,. (2005) Altered luteinizing hormone and testosterone secretion in middle-aged obese men with obstructive sleep apnea. Obesity Research, 13, 780-786.
    • (2005) Obesity Research , vol.13 , pp. 780-786
    • Luboshitzky, R.1    Lavie, L.2    Shen-Orr, Z.3
  • 45
    • 77954647851 scopus 로고    scopus 로고
    • Hypothesis: Kisspeptin mediates male hypogonadism in obesity and type 2 diabetes
    • George, J.T., Millar, R.P., &, Anderson, R.A., (2010) Hypothesis: kisspeptin mediates male hypogonadism in obesity and type 2 diabetes. Neuroendocrinology, 91, 302-307.
    • (2010) Neuroendocrinology , vol.91 , pp. 302-307
    • George, J.T.1    Millar, R.P.2    Anderson, R.A.3
  • 47
    • 56149107529 scopus 로고    scopus 로고
    • Testosterone concentration in young patients with diabetes
    • Chandel, A., Dhindsa, S., Topiwala, S., et al,. (2008) Testosterone concentration in young patients with diabetes. Diabetes Care, 31, 2013-2017.
    • (2008) Diabetes Care , vol.31 , pp. 2013-2017
    • Chandel, A.1    Dhindsa, S.2    Topiwala, S.3
  • 48
    • 70349758939 scopus 로고    scopus 로고
    • Lower serum testosterone is independently associated with insulin resistance in non-diabetic older men: The Health in Men Study
    • Yeap, B.B., Chubb, S.A., Hyde, Z., et al,. (2009) Lower serum testosterone is independently associated with insulin resistance in non-diabetic older men: the Health In Men Study. European journal of endocrinology / European Federation of Endocrine Societies, 161, 591-598.
    • (2009) European Journal of Endocrinology / European Federation of Endocrine Societies , vol.161 , pp. 591-598
    • Yeap, B.B.1    Chubb, S.A.2    Hyde, Z.3
  • 49
    • 40649127931 scopus 로고    scopus 로고
    • Male hypogonadism: The unrecognized cardiovascular risk factor
    • DOI 10.1016/j.jacl.2008.01.011, PII S193328740800010X
    • Potenza, M., &, Shimshi, M., (2008) Male hypogonadism: The unrecognized cardiovascular risk factor. Journal of Clinical Lipidology 2, 71-78. (Pubitemid 351372948)
    • (2008) Journal of Clinical Lipidology , vol.2 , Issue.2 , pp. 71-78
    • Potenza, M.1    Shimshi, M.2
  • 50
    • 77958187103 scopus 로고    scopus 로고
    • Association of testosterone and sex hormone-binding globulin with metabolic syndrome and insulin resistance in men
    • Li, C., Ford, E.S., Li, B., et al,. (2010) Association of testosterone and sex hormone-binding globulin with metabolic syndrome and insulin resistance in men. Diabetes Care, 33, 1618-1624.
    • (2010) Diabetes Care , vol.33 , pp. 1618-1624
    • Li, C.1    Ford, E.S.2    Li, B.3
  • 51
    • 0034703229 scopus 로고    scopus 로고
    • Role of brain insulin receptor in control of body weight and reproduction
    • Bruning, J.C., Gautam, D., Burks, D.J., et al,. (2000) Role of brain insulin receptor in control of body weight and reproduction. Science, 289, 2122-2125.
    • (2000) Science , vol.289 , pp. 2122-2125
    • Bruning, J.C.1    Gautam, D.2    Burks, D.J.3
  • 52
    • 77951642063 scopus 로고    scopus 로고
    • Characteristics of secondary, primary, and compensated hypogonadism in aging men: Evidence from the European Male Ageing Study
    • Tajar, A., Forti, G., O'Neill, T.W., et al,. (2010) Characteristics of secondary, primary, and compensated hypogonadism in aging men: evidence from the European Male Ageing Study. The Journal of Clinical Endocrinology and Metabolism, 95, 1810-1818.
    • (2010) The Journal of Clinical Endocrinology and Metabolism , vol.95 , pp. 1810-1818
    • Tajar, A.1    Forti, G.2    O'Neill, T.W.3
  • 53
    • 0035101072 scopus 로고    scopus 로고
    • The in vitro role of tumour necrosis factor-alpha and interleukin-6 in the hypothalamic-pituitary gonadal axis
    • DOI 10.1046/j.1365-2826.2001.00632.x
    • Russell, S.H., Small, C.J., Stanley, S.A., et al,. (2001) The in vitro role of tumour necrosis factor-alpha and interleukin-6 in the hypothalamic-pituitary gonadal axis. Journal of Neuroendocrinology, 13, 296-301. (Pubitemid 32170995)
    • (2001) Journal of Neuroendocrinology , vol.13 , Issue.3 , pp. 296-301
    • Russell, S.H.1    Small, C.J.2    Stanley, S.A.3    Franks, S.4    Ghatei, M.A.5    Bloom, S.R.6
  • 54
    • 33845467935 scopus 로고    scopus 로고
    • Low testosterone and high C-reactive protein concentrations predict low hematocrit in type 2 diabetes
    • DOI 10.2337/dc06-0637
    • Bhatia, V., Chaudhuri, A., Tomar, R., et al,. (2006) Low testosterone and high C-reactive protein concentrations predict low hematocrit in type 2 diabetes. Diabetes Care, 29, 2289-2294. (Pubitemid 44899867)
    • (2006) Diabetes Care , vol.29 , Issue.10 , pp. 2289-2294
    • Bhatia, V.1    Chaudhuri, A.2    Tomar, R.3    Dhindsa, S.4    Ghanim, H.5    Dandona, P.6
  • 55
    • 34648817335 scopus 로고    scopus 로고
    • Role of inflammatory mediators in the suppression of insulin receptor phosphorylation in circulating mononuclear cells of obese subjects
    • Ghanim, H., Aljada, A., Daoud, N., et al,. (2007) Role of inflammatory mediators in the suppression of insulin receptor phosphorylation in circulating mononuclear cells of obese subjects. Diabetologia, 50, 278-285.
    • (2007) Diabetologia , vol.50 , pp. 278-285
    • Ghanim, H.1    Aljada, A.2    Daoud, N.3
  • 56
    • 70349235444 scopus 로고    scopus 로고
    • Sex hormone-binding globulin and risk of type 2 diabetes in women and men
    • Ding, E.L., Song, Y., Manson, J.E., et al,. (2009) Sex hormone-binding globulin and risk of type 2 diabetes in women and men. The New England Journal of Medicine, 361, 1152-1163.
    • (2009) The New England Journal of Medicine , vol.361 , pp. 1152-1163
    • Ding, E.L.1    Song, Y.2    Manson, J.E.3
  • 57
    • 77949911881 scopus 로고    scopus 로고
    • Genetic evidence that raised sex hormone binding globulin (SHBG) levels reduce the risk of type 2 diabetes
    • Perry, J.R., Weedon, M.N., Langenberg, C., et al,. (2010) Genetic evidence that raised sex hormone binding globulin (SHBG) levels reduce the risk of type 2 diabetes. Human Molecular Genetics, 19, 535-544.
    • (2010) Human Molecular Genetics , vol.19 , pp. 535-544
    • Perry, J.R.1    Weedon, M.N.2    Langenberg, C.3
  • 59
    • 77954742819 scopus 로고    scopus 로고
    • Serum free testosterone and metabolic syndrome in Japanese men
    • Katabami, T., Kato, H., Asahina, T., et al,. (2010) Serum free testosterone and metabolic syndrome in Japanese men. Endocrine Journal, 57, 533-539.
    • (2010) Endocrine Journal , vol.57 , pp. 533-539
    • Katabami, T.1    Kato, H.2    Asahina, T.3
  • 61
    • 51249113647 scopus 로고    scopus 로고
    • The effects of testosterone on sleep and sleep-disordered breathing in men: Its bidirectional interaction with erectile function
    • Andersen, M.L., &, Tufik, S., (2008) The effects of testosterone on sleep and sleep-disordered breathing in men: its bidirectional interaction with erectile function. Sleep Medicine Reviews, 12, 365-379.
    • (2008) Sleep Medicine Reviews , vol.12 , pp. 365-379
    • Andersen, M.L.1    Tufik, S.2
  • 62
    • 0036384408 scopus 로고    scopus 로고
    • Body fat distribution, serum leptin, and cardiovascular risk factors in men with obstructive sleep apnea
    • Schafer, H., Pauleit, D., Sudhop, T., et al,. (2002) Body fat distribution, serum leptin, and cardiovascular risk factors in men with obstructive sleep apnea. Chest, 122, 829-839.
    • (2002) Chest , vol.122 , pp. 829-839
    • Schafer, H.1    Pauleit, D.2    Sudhop, T.3
  • 63
    • 84866682572 scopus 로고    scopus 로고
    • Effects of testosterone therapy on sleep and breathing in obese men with severe obstructive sleep apnea: A randomised placebo-controlled trial
    • Hoyos, C.M., Killick, R., Yee, B.J., et al,. (2012) Effects of testosterone therapy on sleep and breathing in obese men with severe obstructive sleep apnea: a randomised placebo-controlled trial. Clinical Endocrinology (Oxford), 77, 599-607.
    • (2012) Clinical Endocrinology (Oxford) , vol.77 , pp. 599-607
    • Hoyos, C.M.1    Killick, R.2    Yee, B.J.3
  • 64
    • 79960341473 scopus 로고    scopus 로고
    • Evaluation of testosterone serum levels in patients with obstructive sleep apnea syndrome
    • Molina, F.D., Suman, M., Carvalho, T.B., et al,. (2011) Evaluation of testosterone serum levels in patients with obstructive sleep apnea syndrome. Brazilian Journal of Otorhinolaryngology, 77, 88-95.
    • (2011) Brazilian Journal of Otorhinolaryngology , vol.77 , pp. 88-95
    • Molina, F.D.1    Suman, M.2    Carvalho, T.B.3
  • 66
    • 79957464811 scopus 로고    scopus 로고
    • Sleep apnea, reproductive hormones and quality of sexual life in severely obese men
    • Hammoud, A.O., Walker, J.M., Gibson, M., et al,. (2011) Sleep apnea, reproductive hormones and quality of sexual life in severely obese men. Obesity, 19, 1118-1123.
    • (2011) Obesity , vol.19 , pp. 1118-1123
    • Hammoud, A.O.1    Walker, J.M.2    Gibson, M.3


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