Changes in corneal sensation and ocular surface in patients with asymmetrical keratoconus

Cornea

Volumn 32, Issue 2, 2013, Pages 205-210

  Cho, Kyong Jin ^a   Mok, Jee Won ^b   Choi, Min Yeong ^b   Kim, Ja Yeon ^b   Joo, Choun Ki ^b,c  

^a Dankook University   (South Korea)

^b The Catholic University of Korea   (South Korea)

^c The Catholic University of Korea   (South Korea)

Author keywords

corneal sensitivity; impression cytology; keratoconus; ocular surface disease; tear deficiency; tear osmolarity

Indexed keywords

ADULT; ARTICLE; CANCER GRADING; CASE CONTROL STUDY; CLINICAL ARTICLE; CLINICAL FEATURE; CONTACT LENS; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORNEA; FEMALE; GOBLET CELL; HUMAN; HYDROGEL; IMPRESSION CYTOLOGY; KERATOCONUS; LACRIMAL FLUID; MALE; MEASUREMENT; OCULAR SURFACE CHANGE; OSMOLARITY; PRIORITY JOURNAL; PROSPECTIVE STUDY; SCHIRMER TEST; SLIT LAMP; SQUAMOUS CELL METAPLASIA; TOPICAL ANESTHESIA; TOPOGRAPHY; VISUAL SYSTEM PARAMETERS;

ADOLESCENT; ADULT; CASE-CONTROL STUDIES; CONJUNCTIVA; CORNEAL DISEASES; FEMALE; HUMANS; KERATOCONUS; MALE; METAPLASIA; OSMOLAR CONCENTRATION; PROSPECTIVE STUDIES; SENSATION DISORDERS; TEARS; YOUNG ADULT;

EID: 84872949176     PISSN: 02773740     EISSN: 15364798     Source Type: Journal    
DOI: 10.1097/ICO.0b013e3182632c07     Document Type: Article

References (27)

1. Jacobs DS, Dohlman CH. Is keratoconus genetic? Int Ophthalmol Clin. 1993;33:249-260. (Pubitemid 23155414)
2. Nordan LT. Keratoconus: diagnosis and treatment. Int Ophthalmol Clin. 1997;37:51-63. (Pubitemid 27149006)
3. Rabinowitz YS. Keratoconus. Surv Ophthalmol. 1998;42:297-319. (Pubitemid 28092771)
4. Smolek MK, Klyce SD. Is keratoconus a true ectasia? An evaluation of corneal surface area. Arch Ophthalmol. 2000;118:1179-1186.
5. Collier SA, Madigan MC, Penfold PL. Expression of membrane-type 1 matrix metalloproteinase (MT1-MMP) and MMP-2 in normal and keratoconus corneas. Curr Eye Res. 2000;21:662-668.
6. Zhou L, Sawaguchi S, Twining SS, et al. Expression of degradative enzymes and protease inhibitors in corneas with keratoconus. Invest Ophthalmol Vis Sci. 1998;39:1117-1124. (Pubitemid 28247345)
7. Tervo T. Consecutive demonstration of nerves containing catecholamine and acetylcholinesterase in the rat cornea. Histochemistry. 1977;50:291-299. (Pubitemid 8027356)
8. Marfurt CF, Ellis LC. Immunohistochemical localization of tyrosine hydroxylase in corneal nerves. J Comp Neurol. 1993;336:517-531. (Pubitemid 23292357)
9. Muller LJ, Vrensen GF, Pels L, et al. Architecture of human corneal nerves. Invest Ophthalmol Vis Sci. 1997;38:985-994. (Pubitemid 27193524)
10. Sherwin T, Brookes NH, Loh IP, et al. Cellular incursion into Bowman's membrane in the peripheral cone of the keratoconic cornea. Exp Eye Res. 2002;74:473-482. (Pubitemid 34757025)
11. Stern ME, Beuerman RW, Fox RI, et al. The pathology of dry eye: The interaction between the ocular surface and lacrimal glands. Cornea. 1998;17:584-589. (Pubitemid 28511901)
12. Xu KP, Yagi Y, Tsubota K. Decrease in corneal sensitivity and change in tear function in dry eye. Cornea. 1996;15:235-239. (Pubitemid 26123061)
13. Anshu, Munshi MM, Sathe V, et al. Conjunctival impression cytology in contact lens wearers. Cytopathology. 2001;12:314-320.
14. Tseng SC. Staging of conjunctival squamous metaplasia by impression cytology. Ophthalmology. 1985;92:728-733. (Pubitemid 15059999)
15. Dogru M, Karakaya H, Ozçetin H. Tear function and ocular surface changes in keratoconus. Ophthalmology. 2003;110:1110-1118. (Pubitemid 36676641)
16. Lema I, Sobrino T, Durán JA, et al. Subclinical keratoconus and inflammatory molecules from tears. Br J Ophthalmol. 2009;93:820-824.
17. Al-Aqaba MA, Farai L, Fares U, et al. The morphologic characteristics of corneal nerves in advanced keratoconus as evaluated by acetylcholinesterase technique. Am J Ophthalmol. 2011;152:364-376.
18. Zabala M, Archila EA. Corneal sensitivity and topogometry in keratoconus. CLAO J. 1988;14:210-212. (Pubitemid 18262803)
19. Nichols KK, Mitchell GL, Zadnik K, The repeatability of clinical measurements of dry eye. Cornea. 2004;23:272-285. (Pubitemid 38404279)
20. Teng CC. Electron microscope study of the pathology of keratoconus: I. Am J Ophthalmol. 1963;55:18-47.
21. Ruddle JB, Mackey DA, Downie NA. Clinical progression of keratoconus following a Vth nerve palsy. Clin Experiment Ophthalmol. 2003;31: 363-365. (Pubitemid 37127461)
22. Dartt DA, McCarthy DM, Mercer HJ, et al. Localization of nerves adjacent to goblet cells in rat conjunctiva. Curr Eye Res. 1995;14: 993-1000.
23. Murube J. Tear osmolarity. Ocul Surf. 2006;4:62-73. (Pubitemid 351902296)
24. Pflugfelder SC, Jones D, Ji Z, et al. Altered cytokine balance in the tear fluid and conjunctiva of patients with Sjogren's syndrome keratoconjunctivitis sicca. Curr Eye Res. 1999;19:201-211. (Pubitemid 29500267)
25. Smith VA, Rishmawi H, Hussein H. Tear film MMP accumulation and corneal disease. Br J Ophthalmol. 2001;85:147-153. (Pubitemid 32146751)
26. Lema I, Brea D, Rodríguez-González R, et al. Proteomic analysis of the tear film in patients with keratoconus. Mol Vis. 2010;16:2055-2061.
27. Jun AS, Coppe L, Speck C, et al. Subnormal cytokine profile in the tear fluid of keratoconus patients. PLoS One. 2011;6:e16437.