Integrin αvβ6 as a novel marker for diagnosis and metastatic potential of thyroid carcinoma

Head and Neck Oncology

Volumn 5, Issue 1, 2013, Pages

  Liu, Song ^a,b   Liang, Benjia ^a,b   Gao, Huijie ^a,b   Zhang, Fan ^c   Wang, Ben ^a,b   Dong, Xiaoqun ^d,e   Niu, Jun ^a  

^a SHANDONG UNIVERSITY   (China)

^b BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

^c Weihai Maternal and Child Hospital ^*  (China)

^d UNIVERSITY OF RHODE ISLAND   (United States)

^e UNIVERSITY OF RHODE ISLAND   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHAVBETA6 INTEGRIN; TUMOR MARKER;

ADULT; AGED; ARTICLE; CANCER DIAGNOSIS; CLINICAL FEATURE; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; METASTASIS POTENTIAL; NODULAR GOITER; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; SENSITIVITY AND SPECIFICITY; THYROID ADENOMA; THYROID CARCINOMA; THYROIDITIS;

EID: 84872866973     PISSN: None     EISSN: 17583284     Source Type: Journal    
DOI: None     Document Type: Article

References (33)

1. Yu GP, Li JC, Branovan D, McCormick S, Schantz SP. Thyroid cancer incidence and survival in the national cancer institute surveillance, epidemiology, and end results race/ethnicity groups. Thyroid. 2010 May;20(5):465-73.
2. Kitano M, Rahbari R, Patterson EE, Steinberg SM, Prasad NB, Wang Y, et al. Evaluation of candidate diagnostic micrornas in thyroid fine-needle aspiration biopsy samples. Thyroid. 2012 Mar;22(3):285-91.
3. Pang T, Ihre-Lundgren C, Gill A, McMullen T, Sywak M, Sidhu S, et al. Correlation between indeterminate aspiration cytology and final histopathology of thyroid neoplasms. Surgery. 2010 Sep;148(3):532-7.
4. Torregrossa L, Giannini R, Borrelli N, Sensi E, Melillo RM, Leocata P, et al. CXCR4 expression correlates with the degree of tumor infiltration and BRAF status in papillary thyroid carcinomas. Mod Pathol. 2012 Jan;25(1):46-55.
5. Smith VA, Sessions RB, Lentsch EJ. Cervical lymph node metastasis and papillary thyroid carcinoma: does the compartment involved affect survival? Experience from the SEER database. J Surg Oncol. 2012 Sep 15;106(4):357-62.
6. Hynes RO. Integrins: bidirectional, allosteric signaling machines. Cell. 2002 Sep 20;110(6):673-87. (Pubitemid 35283958)
7. Harburger DS, Calderwood DA. Integrin signalling at a glance. J Cell Sci. 2009 Jan 15;122(Pt 2):159-63.
8. Breuss JM, Gallo J, DeLisser HM, Klimanskaya IV, Folkesson HG, Pittet JF, et al. Expression of the beta 6 integrin subunit in development, neoplasia and tissue repair suggests a role in epithelial remodeling. J Cell Sci. 1995 Jun;108 (Pt 6):2241-51.
9. Yang GY, Xu KS, Pan ZQ, Zhang ZY, Mi YT, Wang JS, et al. Integrin alpha v beta 6 mediates the potential for colon cancer cells to colonize in and metastasize to the liver. Cancer Sci. 2008 May;99(5):879-87.
10. Niu J, Gu X, Turton J, Meldrum C, Howard EW, Agrez M. Integrin-mediated signalling of gelatinase B secretion in colon cancer cells. Biochem Biophys Res Commun. 1998 Aug 10;249(1):287-91. (Pubitemid 28418736)
11. Niu J, Gu X, Ahmed N, Andrews S, Turton J, Bates R, et al. The alphaVbeta6 integrin regulates its own expression with cell crowding: implications for tumour progression. Int J Cancer. 2001 Apr 1;92(1):40-8. (Pubitemid 32187030)
12. Ahmed N, Niu J, Dorahy DJ, Gu X, Andrews S, Meldrum CJ, et al. Direct integrin alphavbeta6-ERK binding: implications for tumour growth. Oncogene. 2002 Feb 21;21(9):1370-80. (Pubitemid 34214502)
13. Niu J, Dorahy DJ, Gu X, Scott RJ, Draganic B, Ahmed N, et al. Integrin expression in colon cancer cells is regulated by the cytoplasmic domain of the beta6 integrin subunit. Int J Cancer. 2002 Jun 1;99(4):529-37. (Pubitemid 34461605)
14. Gu X, Niu J, Dorahy DJ, Scott R, Agrez MV. Integrin alpha(v)beta6- associated ERK2 mediates MMP-9 secretion in colon cancer cells. Br J Cancer. 2002 Jul 29;87(3):348-51.
15. Zhang ZY, Xu KS, Wang JS, Yang GY, Wang W, Wang JY, et al. Integrin alphanvbeta6 acts as a prognostic indicator in gastric carcinoma. Clin Oncol (R Coll Radiol). 2008 Feb;20(1):61-6.
16. Sipos B, Hahn D, Carceller A, Piulats J, Hedderich J, Kalthoff H, et al. Immunohistochemical screening for beta6-integrin subunit expression in adenocarcinomas using a novel monoclonal antibody reveals strong up-regulation in pancreatic ductal adenocarcinomas in vivo and in vitro. Histopathology. 2004 Sep;45(3):226-36. (Pubitemid 39279179)
17. Breuss JM, Gillett N, Lu L, Sheppard D, Pytela R. Restricted distribution of integrin beta 6 mRNA in primate epithelial tissues. J Histochem Cytochem. 1993 Oct;41(10):1521-7. (Pubitemid 23275254)
18. Kawashima A, Tsugawa S, Boku A, Kobayashi M, Minamoto T, Nakanishi I, et al. Expression of alphav integrin family in gastric carcinomas: increased alphavbeta6 is associated with lymph node metastasis. Pathol Res Pract. 2003;199(2):57-64. (Pubitemid 36519495)
19. Hamidi S, Salo T, Kainulainen T, Epstein J, Lerner K, Larjava H. Expression of alpha(v)beta6 integrin in oral leukoplakia. Br J Cancer. 2000 Apr;82(8):1433-40. (Pubitemid 30175910)
20. Elayadi AN, Samli KN, Prudkin L, Liu YH, Bian A, Xie XJ, et al. A peptide selected by biopanning identifies the integrin alphavbeta6 as a prognostic biomarker for nonsmall cell lung cancer. Cancer Res. 2007 Jun 15;67(12):5889-95. (Pubitemid 46985024)
21. Ahmed N, Pansino F, Clyde R, Murthi P, Quinn MA, Rice GE, et al. Overexpression of alpha(v)beta6 integrin in serous epithelial ovarian cancer regulates extracellular matrix degradation via the plasminogen activation cascade. Carcinogenesis. 2002 Feb;23(2):237-44. (Pubitemid 34223999)
22. Paunovic I, Isic T, Havelka M, Tatic S, Cvejic D, Savin S. Combined immunohistochemistry for thyroid peroxidase, galectin-3, CK19 and HBME-1 in differential diagnosis of thyroid tumors. APMIS. 2012 May;120(5):368-79.
23. Nar A, Ozen O, Tutuncu NB, Demirhan B. Cyclin A and cyclin B1 overexpression in differentiated thyroid carcinoma. Med Oncol. 2012 Mar;29(1):294-300.
24. Morari EC, Silva JR, Guilhen AC, Cunha LL, Marcello MA, Soares FA, et al. Muc-1 expression may help characterize thyroid nodules but does not predict patients' outcome. Endocr Pathol. 2010 Dec;21(4):242-9.
25. Mihailovic J, Stefanovic L, Malesevic M, Markoski B. The importance of age over radioiodine avidity as a prognostic factor in differentiated thyroid carcinoma with distant metastases. Thyroid. 2009 Mar;19(3):227-32.
26. Arihiro K, Kaneko M, Fujii S, Inai K, Yokosaki Y. Significance of alpha 9 beta 1 and alpha v beta 6 integrin expression in breast carcinoma. Breast Cancer. 2000 Jan;7(1):19-26.
27. Oh J, Takahashi R, Kondo S, Mizoguchi A, Adachi E, Sasahara RM, et al. The membrane-anchored MMP inhibitor RECK is a key regulator of extracellular matrix integrity and angiogenesis. Cell. 2001 Dec 14;107(6):789-800. (Pubitemid 34033671)
28. Saldanha RG, Molloy MP, Bdeir K, Cines DB, Song X, Uitto PM, et al. Proteomic identification of lynchpin urokinase plasminogen activator receptor protein interactions associated with epithelial cancer malignancy. J Proteome Res. 2007 Mar;6(3):1016-28. (Pubitemid 46480466)
29. Wang J, Zhang Z, Xu K, Sun X, Yang G, Niu W, et al. Suppression of integrin αυβ6 by RNA interference in colon cancer cells inhibits extracellular matrix degradation through the MAPK pathway. Int J Cancer. 2008;123(6):1311-7.
30. Ahmed N, Pansino F, Baker M, Rice G, Quinn M. Association between alphavbeta6 integrin expression, elevated p42/44 kDa MAPK, and plasminogen-dependent matrix degradation in ovarian cancer. J Cell Biochem. 2002;84(4):675-86. (Pubitemid 34113107)
31. Ramos DM, But M, Regezi J, Schmidt BL, Atakilit A, Dang D, et al. Expression of integrin beta 6 enhances invasive behavior in oral squamous cell carcinoma. Matrix Biol. 2002 Apr;21(3):297-307. (Pubitemid 34497020)
32. Zha S, Yegnasubramanian V, Nelson WG, Isaacs WB, De Marzo AM. Cyclooxygenases in cancer: progress and perspective. Cancer Lett. 2004 Nov 8;215(1):1-20. (Pubitemid 39221453)
33. Nystrom ML, McCulloch D, Weinreb PH, Violette SM, Speight PM, Marshall JF, et al. Cyclooxygenase-2 inhibition suppresses alphavbeta6 integrin-dependent oral squamous carcinoma invasion. Cancer Res. 2006 Nov 15;66(22):10833-42. (Pubitemid 44876979)