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Volumn 32, Issue 1, 2013, Pages 140-148

A gene loop containing the floral repressor FLC is disrupted in the early phase of vernalization

Author keywords

chromosome conformation capture; FLC; gene loop; Polycomb; vernalization

Indexed keywords

POLYCOMB GROUP PROTEIN;

EID: 84872855164     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2012.324     Document Type: Article
Times cited : (138)

References (59)
  • 1
    • 79961172475 scopus 로고    scopus 로고
    • A Polycomb-based switch underlying quantitative epigenetic memory
    • Angel A, Song J, Dean C, Howard M (2011) A Polycomb-based switch underlying quantitative epigenetic memory.Nature 476: 105-108
    • (2011) Nature , vol.476 , pp. 105-108
    • Angel, A.1    Song, J.2    Dean, C.3    Howard, M.4
  • 2
    • 29144472375 scopus 로고    scopus 로고
    • A role for the CPF 3′ -end processing machinery in RNAP II-dependent gene looping
    • DOI 10.1101/gad.1362305
    • Ansari A, Hampsey M (2005) A role for the CPF 30-end processing machinery in RNAP II-dependent gene looping.Genes Dev 19: 2969-2978 (Pubitemid 41798113)
    • (2005) Genes and Development , vol.19 , Issue.24 , pp. 2969-2978
    • Ansari, A.1    Hampsey, M.2
  • 4
    • 33646529634 scopus 로고    scopus 로고
    • The timing of developmental transitions in plants
    • Baurle I, Dean C (2006) The timing of developmental transitions in plants.Cell 125: 655-664
    • (2006) Cell , vol.125 , pp. 655-664
    • Baurle, I.1    Dean, C.2
  • 6
    • 79952309663 scopus 로고    scopus 로고
    • The FRIGIDA complex activates transcription of FLC, a strong flowering repressor in Arabidopsis, by recruiting chromatin modification factors
    • Choi K, Kim J, Hwang HJ, Kim S, Park C, Kim SY, Lee I (2011) The FRIGIDA complex activates transcription of FLC, a strong flowering repressor in Arabidopsis, by recruiting chromatin modification factors.Plant Cell 23: 289-303
    • (2011) Plant Cell , vol.23 , pp. 289-303
    • Choi, K.1    Kim, J.2    Hwang, H.J.3    Kim, S.4    Park, C.5    Kim, S.Y.6    Lee, I.7
  • 7
    • 29544451829 scopus 로고    scopus 로고
    • SUPPRESSOR of FRIGIDA3 encodes a nuclear ACTIN-RELATED PROTEIN6 required for floral repression in Arabidopsis
    • Choi K, Kim S, Kim SY, Kim M, Hyun Y, Lee H, Choe S, Kim SG, Michaels S, Lee I (2005) SUPPRESSOR OF FRIGIDA3 encodes a nuclear ACTIN-RELATED PROTEIN6 required for floral repression in Arabidopsis.Plant Cell 17: 2647-2660
    • (2005) Plant Cell , vol.17 , pp. 2647-2660
    • Choi, K.1    Kim, S.2    Kim, S.Y.3    Kim, M.4    Hyun, Y.5    Lee, H.6    Choe, S.7    Kim, S.G.8    Michaels, S.9    Lee, I.10
  • 9
    • 78751501891 scopus 로고    scopus 로고
    • Regulation of the floral repressor gene FLC: The complexity of transcription in a chromatin context
    • Crevillen P, Dean C (2010) Regulation of the floral repressor gene FLC: the complexity of transcription in a chromatin context.Curr Opin Plant Biol 14: 38-44
    • (2010) Curr Opin Plant Biol , vol.14 , pp. 38-44
    • Crevillen, P.1    Dean, C.2
  • 10
    • 32644481938 scopus 로고    scopus 로고
    • Genome-wide identification and testing of superior reference genes for transcript normalization in arabidopsis
    • DOI 10.1104/pp.105.063743
    • Czechowski T, Stitt M, Altmann T, Udvardi MK, Scheible WR (2005) Genome-wide identification and testing of superior reference genes for transcript normalization in Arabidopsis.Plant Physiol 139: 5-17 (Pubitemid 43951587)
    • (2005) Plant Physiology , vol.139 , Issue.1 , pp. 5-17
    • Czechowski, T.1    Stitt, M.2    Altmann, T.3    Udvardi, M.K.4    Scheible, W.-R.5
  • 11
    • 58149217038 scopus 로고    scopus 로고
    • A PHDPolycomb repressive complex 2 triggers the epigenetic silencing of FLC during vernalization
    • De Lucia F, Crevillen P, Jones AM, Greb T, Dean C (2008) A PHDPolycomb repressive complex 2 triggers the epigenetic silencing of FLC during vernalization.Proc Natl Acad Sci USA 105: 16831-16836
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 16831-16836
    • De Lucia, F.1    Crevillen, P.2    Jones, A.M.3    Greb, T.4    Dean, C.5
  • 12
    • 28544445054 scopus 로고    scopus 로고
    • The nuclear actin-related protein ARP6 is a pleiotropic developmental regulator required for the maintenance of FLOWERING LOCUS C expression and repression of flowering in Arabidopsis
    • Deal RB, Kandasamy MK, McKinney EC, Meagher RB (2005) The nuclear actin-related protein ARP6 is a pleiotropic developmental regulator required for the maintenance of FLOWERING LOCUS C expression and repression of flowering in Arabidopsis.Plant Cell 17: 2633-2646
    • (2005) Plant Cell , vol.17 , pp. 2633-2646
    • Deal, R.B.1    Kandasamy, M.K.2    McKinney, E.C.3    Meagher, R.B.4
  • 13
    • 34249820562 scopus 로고    scopus 로고
    • Repression of flowering in Arabidopsis requires activation of FLOWERING LOCUS C expression by the histone variant H2A.Z
    • DOI 10.1105/tpc.106.048447
    • Deal RB, Topp CN, McKinney EC, Meagher RB (2007) Repression of flowering in Arabidopsis requires activation of FLOWERING LOCUS C expression by the histone variant H2A.Z.Plant Cell 19: 74-83 (Pubitemid 46852702)
    • (2007) Plant Cell , vol.19 , Issue.1 , pp. 74-83
    • Deal, R.B.1    Topp, C.N.2    McKinney, E.C.3    Meagher, R.B.4
  • 14
    • 0037083376 scopus 로고    scopus 로고
    • Capturing chromosome conformation
    • DOI 10.1126/science.1067799
    • Dekker J, Rippe K, Dekker M, Kleckner N (2002) Capturing chromosome conformation.Science 295: 1306-1311 (Pubitemid 34157624)
    • (2002) Science , vol.295 , Issue.5558 , pp. 1306-1311
    • Dekker, J.1    Rippe, K.2    Dekker, M.3    Kleckner, N.4
  • 15
    • 84861976397 scopus 로고    scopus 로고
    • Polycomb: A paradigm for genome organization from one to three dimensions
    • Delest A, Sexton T, Cavalli G (2012) Polycomb: a paradigm for genome organization from one to three dimensions.Curr Opin Cell Biol 24: 405-414
    • (2012) Curr Opin Cell Biol , vol.24 , pp. 405-414
    • Delest, A.1    Sexton, T.2    Cavalli, G.3
  • 16
    • 79952299705 scopus 로고    scopus 로고
    • Hypomorphic alleles reveal FCA-independent roles for FY in the regulation of FLOWERING LOCUS C
    • Feng W, Jacob Y, Veley KM, Ding L, Yu X, Choe G, Michaels SD (2011) Hypomorphic alleles reveal FCA-independent roles for FY in the regulation of FLOWERING LOCUS C.Plant Physiol 155: 1425-1434
    • (2011) Plant Physiol , vol.155 , pp. 1425-1434
    • Feng, W.1    Jacob, Y.2    Veley, K.M.3    Ding, L.4    Yu, X.5    Choe, G.6    Michaels, S.D.7
  • 17
    • 36048973238 scopus 로고    scopus 로고
    • Vernalization-Induced Trimethylation of Histone H3 Lysine 27 at FLC Is Not Maintained in Mitotically Quiescent Cells
    • DOI 10.1016/j.cub.2007.10.026, PII S0960982207020878
    • Finnegan EJ, Dennis ES (2007) Vernalization-induced trimethylation of histone H3 lysine 27 at FLC is not maintained in mitotically quiescent cells.Curr Biol 17: 1978-1983 (Pubitemid 350088488)
    • (2007) Current Biology , vol.17 , Issue.22 , pp. 1978-1983
    • Finnegan, E.J.1    Dennis, E.S.2
  • 18
    • 67650143299 scopus 로고    scopus 로고
    • FRIGIDA delays flowering in Arabidopsis via a co-transcriptional mechanism involving direct interaction with the nuclear cap binding complex
    • Geraldo N, Baurle I, Kidou SI, Hu X, Dean C (2009) FRIGIDA delays flowering in Arabidopsis via a co-transcriptional mechanism involving direct interaction with the nuclear cap binding complex.Plant Physiol 150: 1611-1618
    • (2009) Plant Physiol , vol.150 , pp. 1611-1618
    • Geraldo, N.1    Baurle, I.2    Kidou, S.I.3    Hu, X.4    Dean, C.5
  • 19
    • 33845872285 scopus 로고    scopus 로고
    • The PHD Finger Protein VRN5 Functions in the Epigenetic Silencing of Arabidopsis FLC
    • DOI 10.1016/j.cub.2006.11.052, PII S096098220602570X
    • Greb T, Mylne JS, Crevillen P, Geraldo N, An H, Gendall AR, Dean C (2007) The PHD finger protein VRN5 functions in the epigenetic silencing of Arabidopsis FLC.Curr Biol 17: 73-78 (Pubitemid 46027584)
    • (2007) Current Biology , vol.17 , Issue.1 , pp. 73-78
    • Greb, T.1    Mylne, J.S.2    Crevillen, P.3    Geraldo, N.4    An, H.5    Gendall, A.R.6    Dean, C.7
  • 21
    • 78650966670 scopus 로고    scopus 로고
    • Vernalization-mediated epigenetic silencing by a long intronic noncoding RNA
    • Heo JB, Sung S (2010) Vernalization-mediated epigenetic silencing by a long intronic noncoding RNA.Science 331: 76-79
    • (2010) Science , vol.331 , pp. 76-79
    • Heo, J.B.1    Sung, S.2
  • 22
    • 76249122261 scopus 로고    scopus 로고
    • The Spen family protein FPA controls alternative cleavage and polyadenylation of RNA
    • Hornyik C, Terzi LC, Simpson GG (2010) The Spen family protein FPA controls alternative cleavage and polyadenylation of RNA.Dev Cell 18: 203-213
    • (2010) Dev Cell , vol.18 , pp. 203-213
    • Hornyik, C.1    Terzi, L.C.2    Simpson, G.G.3
  • 23
    • 84865192845 scopus 로고    scopus 로고
    • Flowering time control: Another window to the connection between antisense RNA and chromatin
    • Ietswaart R, Wu Z, Dean C (2012) Flowering time control: another window to the connection between antisense RNA and chromatin.Trends Genet 28: 445-453
    • (2012) Trends Genet , vol.28 , pp. 445-453
    • Ietswaart, R.1    Wu, Z.2    Dean, C.3
  • 26
    • 34848825691 scopus 로고    scopus 로고
    • Polycomb response elements mediate the formation of chromosome higher-order structures in the bithorax complex
    • DOI 10.1038/ncb1637, PII NCB1637
    • Lanzuolo C, Roure V, Dekker J, Bantignies F, Orlando V (2007) Polycomb response elements mediate the formation of chromosome higher-order structures in the bithorax complex.Nat Cell Biol 9: 1167-1174 (Pubitemid 47500493)
    • (2007) Nature Cell Biology , vol.9 , Issue.10 , pp. 1167-1174
    • Lanzuolo, C.1    Roure, V.2    Dekker, J.3    Bantignies, F.4    Orlando, V.5
  • 27
    • 84864008380 scopus 로고    scopus 로고
    • Dynamic reconfiguration of long human genes during one transcription cycle
    • Larkin JD, Cook PR, Papantonis A (2012) Dynamic reconfiguration of long human genes during one transcription cycle.Mol Cell Biol 32: 2738-2747
    • (2012) Mol Cell Biol , vol.32 , pp. 2738-2747
    • Larkin, J.D.1    Cook, P.R.2    Papantonis, A.3
  • 28
    • 33847070442 scopus 로고    scopus 로고
    • The Role of Chromatin during Transcription
    • DOI 10.1016/j.cell.2007.01.015, PII S0092867407001092
    • Li B, Carey M, Workman JL (2007) The role of chromatin during transcription.Cell 128: 707-719 (Pubitemid 46273570)
    • (2007) Cell , vol.128 , Issue.4 , pp. 707-719
    • Li, B.1    Carey, M.2    Workman, J.L.3
  • 29
    • 74849099777 scopus 로고    scopus 로고
    • Targeted 30 processing of antisense transcripts triggers Arabidopsis FLC chromatin silencing
    • Liu F, Marquardt S, Swiezewski S, Dean C (2010) Targeted 30 processing of antisense transcripts triggers Arabidopsis FLC chromatin silencing.Science 327: 94-97
    • (2010) Science , vol.327 , pp. 94-97
    • Liu, F.1    Marquardt, S.2    Swiezewski, S.3    Dean, C.4
  • 30
    • 35648982312 scopus 로고    scopus 로고
    • The Arabidopsis RNA-Binding Protein FCA Requires a Lysine-Specific Demethylase 1 Homolog to Downregulate FLC
    • DOI 10.1016/j.molcel.2007.10.018, PII S1097276507007009
    • Liu F, Quesada V, Crevillen P, Bäurle I, Swiezewski S, Dean C (2007) The Arabidopsis RNA-binding protein FCA requires a lysinespecific demethylase 1 homolog to downregulate.FLC Mol Cell 28: 398-407 (Pubitemid 350030571)
    • (2007) Molecular Cell , vol.28 , Issue.3 , pp. 398-407
    • Liu, F.1    Quesada, V.2    Crevillen, P.3    Baurle, I.4    Swiezewski, S.5    Dean, C.6
  • 31
    • 66449105851 scopus 로고    scopus 로고
    • Tissue-and expression level-specific chromatin looping at maize b1 epialleles
    • Louwers M, Bader R, Haring M, van Driel R, de Laat W, Stam M (2009a) Tissue- and expression level-specific chromatin looping at maize b1 epialleles.Plant Cell 21: 832-842
    • (2009) Plant Cell , vol.21 , pp. 832-842
    • Louwers, M.1    Bader, R.2    Haring, M.3    Van Driel, R.4    De Laat, W.5    Stam, M.6
  • 32
    • 68449092480 scopus 로고    scopus 로고
    • Studying physical chromatin interactions in plants using Chromosome Conformation Capture (3C)
    • Louwers M, Splinter E, van Driel R, de Laat W, Stam M (2009b) Studying physical chromatin interactions in plants using Chromosome Conformation Capture (3C).Nat Protoc 4: 1216-1229
    • (2009) Nat Protoc , vol.4 , pp. 1216-1229
    • Louwers, M.1    Splinter, E.2    Van Driel, R.3    De Laat, W.4    Stam, M.5
  • 33
    • 79952631797 scopus 로고    scopus 로고
    • An ending is a new beginning: Transcription termination supports re-initiation
    • Lykke-Andersen S, Mapendano CK, Jensen TH (2011) An ending is a new beginning: transcription termination supports re-initiation.Cell Cycle 10: 863-865
    • (2011) Cell Cycle , vol.10 , pp. 863-865
    • Lykke-Andersen, S.1    Mapendano, C.K.2    Jensen, T.H.3
  • 34
    • 33646130847 scopus 로고    scopus 로고
    • EARLY in SHORT DAYS 1 (ESD1) encodes ACTIN-RELATED PROTEIN 6 (AtARP6), a putative component of chromatin remodelling complexes that positively regulates FLC accumulation in Arabidopsis
    • Martin-Trillo M, Lazaro A, Poethig RS, Gomez-Mena C, Pineiro MA, Martinez-Zapater JM, Jarillo JA (2006) EARLY IN SHORT DAYS 1 (ESD1) encodes ACTIN-RELATED PROTEIN 6 (AtARP6), a putative component of chromatin remodelling complexes that positively regulates FLC accumulation in Arabidopsis.Development 133: 1241-1252
    • (2006) Development , vol.133 , pp. 1241-1252
    • Martin-Trillo, M.1    Lazaro, A.2    Poethig, R.S.3    Gomez-Mena, C.4    Pineiro, M.A.5    Martinez-Zapater, J.M.6    Jarillo, J.A.7
  • 35
    • 80053190826 scopus 로고    scopus 로고
    • Evidence for a complex of transcription factor IIB with poly(A) polymerase and cleavage factor 1 subunits required for gene looping
    • Medler S, Al Husini N, Raghunayakula S, Mukundan B, Aldea A, Ansari A (2011) Evidence for a complex of transcription factor IIB with poly(A) polymerase and cleavage factor 1 subunits required for gene looping.J Biol Chem 286: 33709-33718
    • (2011) J Biol Chem , vol.286 , pp. 33709-33718
    • Medler, S.1    Al Husini, N.2    Raghunayakula, S.3    Mukundan, B.4    Aldea, A.5    Ansari, A.6
  • 36
    • 0033133554 scopus 로고    scopus 로고
    • FLOWERING LOCUS C encodes a novel MADS domain protein that acts as a repressor of flowering
    • Michaels SD, Amasino RM (1999) FLOWERING LOCUS C encodes a novel MADS domain protein that acts as a repressor of flowering.Plant Cell 11: 949-956
    • (1999) Plant Cell , vol.11 , pp. 949-956
    • Michaels, S.D.1    Amasino, R.M.2
  • 37
    • 84861912048 scopus 로고    scopus 로고
    • Role for gene looping in intron-mediated enhancement of transcription
    • Moabbi AM, Agarwal N, El Kaderi B, Ansari A (2012) Role for gene looping in intron-mediated enhancement of transcription.Proc Natl Acad Sci USA 109: 8505-8510
    • (2012) Proc Natl Acad Sci USA , vol.109 , pp. 8505-8510
    • Moabbi, A.M.1    Agarwal, N.2    El Kaderi, B.3    Ansari, A.4
  • 39
    • 84859335229 scopus 로고    scopus 로고
    • A pre-initiation complex at the 30-end of genes drives antisense transcription independent of divergent sense transcription
    • Murray SC, Serra Barros A, Brown DA, Dudek P, Ayling J, Mellor J (2012) A pre-initiation complex at the 30-end of genes drives antisense transcription independent of divergent sense transcription.Nucleic Acids Res 40: 2432-2444
    • (2012) Nucleic Acids Res , vol.40 , pp. 2432-2444
    • Murray, S.C.1    Serra Barros, A.2    Brown, D.A.3    Dudek, P.4    Ayling, J.5    Mellor, J.6
  • 41
    • 34547436788 scopus 로고    scopus 로고
    • Cell-type-specific expression of the human CD68 gene is associated with changes in Pol II phosphorylation and short-range intrachromosomal gene looping
    • DOI 10.1016/j.ygeno.2007.04.010, PII S0888754307000997
    • O'Reilly D, Greaves DR (2007) Cell-type-specific expression of the human CD68 gene is associated with changes in Pol II phosphorylation and short-range intrachromosomal gene looping.Genomics 90: 407-415 (Pubitemid 47176331)
    • (2007) Genomics , vol.90 , Issue.3 , pp. 407-415
    • O'Reilly, D.1    Greaves, D.R.2
  • 43
    • 70349542588 scopus 로고    scopus 로고
    • Close encounters of the 3C kind: Long-range chromatin interactions and transcriptional regulation
    • Palstra RJ (2009) Close encounters of the 3C kind: long-range chromatin interactions and transcriptional regulation.Brief Funct Genomic Proteomic 8: 297-309
    • (2009) Brief Funct Genomic Proteomic , vol.8 , pp. 297-309
    • Palstra, R.J.1
  • 44
    • 38149020517 scopus 로고    scopus 로고
    • Transcription-dependent gene looping of the HIV-1 provirus is dictated by recognition of pre-mRNA processing signals
    • Perkins KJ, Lusic M, Mitar I, Giacca M, Proudfoot NJ (2008) Transcription-dependent gene looping of the HIV-1 provirus is dictated by recognition of pre-mRNA processing signals.Mol Cell 29: 56-68
    • (2008) Mol Cell , vol.29 , pp. 56-68
    • Perkins, K.J.1    Lusic, M.2    Mitar, I.3    Giacca, M.4    Proudfoot, N.J.5
  • 45
    • 48249095591 scopus 로고    scopus 로고
    • Arabidopsis Trithorax1 dynamically regulates Flowering Locus C activation via histone 3 lysine 4 trimethylation
    • DOI 10.1105/tpc.108.058172
    • Pien S, Fleury D, Mylne JS, Crevillen P, Inze D, Avramova Z, Dean C, Grossniklaus U (2008) ARABIDOPSIS TRITHORAX1 Dynamically regulates FLOWERING LOCUS C activation via Histone 3 Lysine 4 trimethylation.Plant Cell 20: 580-588 (Pubitemid 352843994)
    • (2008) Plant Cell , vol.20 , Issue.3 , pp. 580-588
    • Pien, S.1    Fleury, D.2    Mylne, J.S.3    Crevillen, P.4    Inze, D.5    Avramova, Z.6    Dean, C.7    Grossniklaus, U.8
  • 46
    • 34548219406 scopus 로고    scopus 로고
    • A Transcription-Independent Role for TFIIB in Gene Looping
    • DOI 10.1016/j.molcel.2007.07.013, PII S1097276507004868
    • Singh BN, Hampsey M (2007) A transcription-independent role for TFIIB in gene looping.Mol Cell 27: 806-816 (Pubitemid 47333227)
    • (2007) Molecular Cell , vol.27 , Issue.5 , pp. 806-816
    • Singh, B.N.1    Hampsey, M.2
  • 47
    • 84868514154 scopus 로고    scopus 로고
    • Vernalization - A coldinduced epigenetic switch
    • Song J, Angel A, Howard M, Dean C (2012) Vernalization - a coldinduced epigenetic switch.J Cell Sci 125: 3723-3731
    • (2012) J Cell Sci , vol.125 , pp. 3723-3731
    • Song, J.1    Angel, A.2    Howard, M.3    Dean, C.4
  • 50
    • 0347717907 scopus 로고    scopus 로고
    • Vernalization in Arabidopsis thaliana is mediated by the PHD finger protein VIN3
    • DOI 10.1038/nature02195
    • Sung S, Amasino RM (2004) Vernalization in Arabidopsis thaliana is mediated by the PHD finger protein VIN3.Nature 427: 159-164 (Pubitemid 38094956)
    • (2004) Nature , vol.427 , Issue.6970 , pp. 159-164
    • Sung, S.1    Amasino, R.M.2
  • 51
    • 33845381753 scopus 로고    scopus 로고
    • A PHD finger protein involved in both the vernalization and photoperiod pathways in Arabidopsis
    • DOI 10.1101/gad.1493306
    • Sung S, Schmitz RJ, Amasino RM (2006) A PHD finger protein involved in both the vernalization and photoperiod pathways in Arabidopsis.Genes Dev 20: 3244-3248 (Pubitemid 44904846)
    • (2006) Genes and Development , vol.20 , Issue.23 , pp. 3244-3248
    • Sung, S.1    Schmitz, R.J.2    Amasino, R.M.3
  • 53
    • 72049133207 scopus 로고    scopus 로고
    • Cold-induced silencing by long antisense transcripts of an Arabidopsis Polycomb target
    • Swiezewski S, Liu F, Magusin A, Dean C (2009) Cold-induced silencing by long antisense transcripts of an Arabidopsis Polycomb target.Nature 462: 799-802
    • (2009) Nature , vol.462 , pp. 799-802
    • Swiezewski, S.1    Liu, F.2    Magusin, A.3    Dean, C.4
  • 55
    • 72749098124 scopus 로고    scopus 로고
    • Gene loops function to maintain transcriptional memory through interaction with the nuclear pore complex
    • Tan-Wong SM, Wijayatilake HD, Proudfoot NJ (2009) Gene loops function to maintain transcriptional memory through interaction with the nuclear pore complex.Genes Dev 23: 2610-2624
    • (2009) Genes Dev , vol.23 , pp. 2610-2624
    • Tan-Wong, S.M.1    Wijayatilake, H.D.2    Proudfoot, N.J.3
  • 58
    • 0036923833 scopus 로고    scopus 로고
    • Looping and interaction between hypersensitive sites in the active β-globin locus
    • DOI 10.1016/S1097-2765(02)00781-5
    • Tolhuis B, Palstra RJ, Splinter E, Grosveld F, de Laat W (2002) Looping and interaction between hypersensitive sites in the active beta-globin locus.Mol Cell 10: 1453-1465 (Pubitemid 36050885)
    • (2002) Molecular Cell , vol.10 , Issue.6 , pp. 1453-1465
    • Tolhuis, B.1    Palstra, R.-J.2    Splinter, E.3    Grosveld, F.4    De Laat, W.5


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