Nasal polyposis: An inflammatory condition requiring effective anti-inflammatory treatment

Current Opinion in Otolaryngology and Head and Neck Surgery

Volumn 21, Issue 1, 2013, Pages 23-30

  Chin, David ^a,b   Harvey, Richard J ^a,c,d  

^a St Vincent's University   (Australia)

^b CHANGI GENERAL HOSPITAL   (Singapore)

^c MACQUARIE UNIVERSITY   (Australia)

^d UNIVERSITY OF NEW SOUTH WALES   (Australia)

Author keywords

chronic rhinosinusitis; corticosteroid; endoscopic sinus surgery; eosinophilic; irrigations

Indexed keywords

BUDESONIDE; CYANOCOBALAMIN; INTERLEUKIN 17; INTERLEUKIN 25; INTERLEUKIN 33; INTERLEUKIN 5;

ADAPTIVE IMMUNITY; ALLERGIC RHINITIS; ANTIINFLAMMATORY ACTIVITY; ASTHMA; BRONCHUS REACTIVITY; CHRONIC RHINOSINUSITIS; CLINICAL PRACTICE; DIAGNOSTIC ACCURACY; DISEASE CONTROL; DISEASE SEVERITY; ENDOSCOPIC SINUS SURGERY; EOSINOPHILIA; HISTOPATHOLOGY; HUMAN; IMMUNE DYSREGULATION; INNATE IMMUNITY; META ANALYSIS (TOPIC); NOSE POLYP; PHENOTYPE; PRIORITY JOURNAL; PROGNOSIS; RANDOMIZED CONTROLLED TRIAL (TOPIC); RECURRENT DISEASE; RESPIRATORY EPITHELIUM; REVIEW; STEROID THERAPY; TH2 CELL;

ADMINISTRATION, TOPICAL; ANTI-INFLAMMATORY AGENTS; CHRONIC DISEASE; HUMANS; IMMUNITY, INNATE; INFLAMMATION; NASAL POLYPS; RHINITIS; SINUSITIS;

EID: 84872846863     PISSN: 10689508     EISSN: 15316998     Source Type: Journal    
DOI: 10.1097/MOO.0b013e32835bc3f9     Document Type: Review

References (60)

1. Fokkens WJ, Lund VJ, Mullol J, et al. European position paper on rhinosinusitis and nasal polyps 2012. Rhinol Suppl 2012; 3:1-298.
2. Kern RC, Conley DB, Walsh W, et al. Perspectives on the etiology of chronic rhinosinusitis: an immune barrier hypothesis. Am J Rhinol 2008; 22:549-559.
3. Timperley D, Schlosser RJ, Harvey RJ. Chronic rhinosinusitis: an education and treatment model. Otolaryngol Head Neck Surg 2010; 143:S3-S8.
4. Van Zele T, Claeys S, Gevaert P, et al. Differentiation of chronic sinus diseases by measurement of inflammatory mediators. Allergy 2006; 61:1280-1289.
5. Bachert C, Zhang N, Holtappels G, et al. Presence of IL-5 protein and IgE antibodies to staphylococcal enterotoxins in nasal polyps is associated with comorbid asthma. J Allergy Clin Immunol 2010; 126:962-968; 968 e961-966.
6. Zhang N, Van Zele T, Perez-Novo C, et al. Different types of T-effector cells orchestrate mucosal inflammation in chronic sinus disease. J Allergy Clin Immunol 2008; 122:961-968.
7. Jiang XD, Li GY, Li L, et al. The characterization of IL-17A expression in patients with chronic rhinosinusitis with nasal polyps. Am J Rhinol Allergy 2011; 25:e171-e175.
8. Wen W, Liu W, Zhang L, et al. Increased neutrophilia in nasal polyps reduces the response to oral corticosteroid therapy. J Allergy Clin Immunol 2012; 129:1522-1528; e1525..
9. Holgate ST. The sentinel role of the airway epithelium in asthma pathogenesis. Immunol Rev 2011; 242:205-219.
10. Hammad H, Lambrecht BN. Dendritic cells and airway epithelial cells at the interface between innate and adaptive immune responses. Allergy 2011; 66:579-587.
11. Takeno S, Hirakawa K, Ishino T. Pathological mechanisms and clinical features of eosinophilic chronic rhinosinusitis in the Japanese population. Allergol Int 2010; 59:247-256.
12. Coffman RL. Immunology: the origin of TH2 responses. Science 2010; 328:1116-1117.
13. Reh DD, Wang Y, Ramanathan M Jr, Lane AP. Treatment-recalcitrant chronic rhinosinusitis with polyps is associated with altered epithelial cell expression of interleukin-33. Am J Rhinol Allergy 2010; 24:105-109.
14. Lam MH L, McLacklan R, Snidvongs K, et al. IL-25 and IL-33 as mediators of eosinophilic inflammation in chronic rhinosinusitis. J Allergy Clin Immunol 2012; (in press).
15. Wang YH, Angkasekwinai P, Lu N, et al. IL-25 augments type 2 immune responses by enhancing the expansion and functions of TSLP-DC-activated Th2 memory cells. J Exp Med 2007; 204:1837-1847.
16. Koyasu S, Moro K. Type 2 innate immune responses and the natural helper cell. Immunology 2011; 132:475-481.
17. Koyasu S, Moro K. Innate Th2-type immune responses and the natural helper cell, a newly identified lymphocyte population. Curr Opin Allergy Clin Immunol 2011; 11:109-114.
18. Mjosberg JM, Trifari S, Crellin NK, et al. Human IL-25-and IL-33-responsive type 2 innate lymphoid cells are defined by expression of CRTH2 and CD161. Nat Immunol 2011; 12:1055-1062.
19. Ito T, Liu YJ, Arima K. Cellular and molecular mechanisms of TSLP function in human allergic disorders-TSLP programs the 'Th2 code' in dendritic cells. Allergol Int 2012; 61:35-43.
20. Boita M, Garzaro M, Raimondo L, et al. The expression of TSLP receptor in chronic rhinosinusitis with and without nasal polyps. Int J Immunopathol Pharmacol 2011; 24:761-768.
21. Liu YJ, Soumelis V, Watanabe N, et al. TSLP: an epithelial cell cytokine that regulates T cell differentiation by conditioning dendritic cell maturation. Annu Rev Immunol 2007; 25:193-219.
22. Harada M, Hirota T, Jodo AI, et al. Thymic stromal lymphopoietin gene promoter polymorphisms are associated with susceptibility to bronchial asthma. Am J Respir Cell Mol Biol 2011; 44:787-793.
23. Shikotra A, Choy DF, Ohri CM, et al. Increased expression of immunoreactive thymic stromal lymphopoietin in patients with severe asthma. J Allergy Clin Immunol 2012; 129:104-111; e101-109.
24. Kim YM, Munoz A, Hwang PH, Nadeau KC. Migration of regulatory T cells toward airway epithelial cells is impaired in chronic rhinosinusitis with nasal polyposis. Clin Immunol 2010; 137:111-121.
25. Roongrotwattanasiri K, Pawankar R, Kimura S, et al. Decreased expression of FOXP3 in nasal polyposis. Allergy Asthma Immunol Res 2012; 4:24-30.
26. Van Bruaene N, Perez-Novo CA, Basinski TM, et al. T-cell regulation in chronic paranasal sinus disease. J Allergy Clin Immunol 2008; 121:1435-1441; 1441 e1431-1433.
27. Van Bruaene N, Derycke L, Perez-Novo CA, et al. TGF-beta signaling and collagen deposition in chronic rhinosinusitis. J Allergy Clin Immunol 2009; 124:253-259; 259 e251-252.
28. Van Crombruggen K, Zhang N, Gevaert P, et al. Pathogenesis of chronic rhinosinusitis: inflammation. J Allergy Clin Immunol 2011; 128:728-732.
29. Pezato R, Voegels RL. Why do we not find polyps in the lungs? Bronchial mucosa as a model in the treatment of polyposis. Med Hypotheses 2012; 78:468-470.
30. Szczeklik A, Stevenson DD. Aspirin-induced asthma: advances in pathogenesis, diagnosis, and management. J Allergy Clin Immunol 2003; 111:913-921; quiz 922.
31. Ragab A, Clement P, Vincken W. Objective assessment of lower airway involvement in chronic rhinosinusitis. Am J Rhinol 2004; 18:15-21.
32. Chanez P, Vignola AM, Vic P, et al. Comparison between nasal and bronchial inflammation in asthmatic and control subjects. Am J Respir Crit Care Med 1999; 159:588-595.
33. ten Brinke A, Grootendorst DC, Schmidt JT, et al. Chronic sinusitis in severe asthma is related to sputum eosinophilia. J Allergy Clin Immunol 2002; 109:621-626.
34. Amorim MM, Araruna A, Caetano LB, et al. Nasal eosinophilia: an indicator of eosinophilic inflammation in asthma. Clin Exp Allergy 2010; 40:867-874.
35. Sakuma Y, Ishitoya J, Komatsu M, et al. New clinical diagnostic criteria for eosinophilic chronic rhinosinusitis. Auris Nasus Larynx 2011; 38:583-588.
36. Braunstahl GJ, Kleinjan A, Overbeek SE, et al. Segmental bronchial provocation induces nasal inflammation in allergic rhinitis patients. Am J Respir Crit Care Med 2000; 161:2051-2057.
37. Braunstahl GJ, Overbeek SE, Kleinjan A, et al. Nasal allergen provocation induces adhesion molecule expression and tissue eosinophilia in upper and lower airways. J Allergy Clin Immunol 2001; 107:469-476.
38. Williamson PA, Vaidyanathan S, Clearie K, et al. Airway dysfunction in nasal polyposis: a spectrum of asthmatic disease? Clin Exp Allergy 2011; 41:1379-1385.
39. Braunstahl GJ. Chronic rhinosinusitis, nasal polyposis and asthma: the united airways concept reconsidered? Clin Exp Allergy 2011; 41:1341-1343.
40. Batra PS, Kern RC, Tripathi A, et al. Outcome analysis of endoscopic sinus surgery in patients with nasal polyps and asthma. Laryngoscope 2003; 113:1703-1706.
41. Proimos E, Papadakis CE, Chimona TS, et al. The effect of functional endoscopic sinus surgery on patients with asthma and CRS with nasal polyps. Rhinology 2010; 48:331-338.
42. Ehnhage A, Olsson P, Kolbeck KG, et al. One year after endoscopic sinus surgery in polyposis: asthma, olfaction, and quality-of-life outcomes. Otolaryngol Head Neck Surg 2012; 146:834-841.
43. Ragab S, Scadding GK, Lund VJ, Saleh H. Treatment of chronic rhinosinusitis and its effects on asthma. Eur Respir J 2006; 28:68-74.
44. Uri N, Cohen-Kerem R, Barzilai G, et al. Functional endoscopic sinus surgery in the treatment of massive polyposis in asthmatic patients. J Laryngol Otol 2002; 116:185-189.
45. Payne SC, Early SB, Huyett P, et al. Evidence for distinct histologic profile of nasal polyps with and without eosinophilia. Laryngoscope 2011; 121:2262-2267.
46. Snidvongs K, Lam M, Sacks R, et al. Structured histopathology profiling of chronic rhinosinusitis in routine practice. Int Forum Allergy Rhinol 2012; 2:376-385.
47. Soler ZM, Sauer D, Mace J, Smith TL. Impact of mucosal eosinophilia and nasal polyposis on quality-of-life outcomes after sinus surgery. Otolaryngol Head Neck Surg 2010; 142:64-71.
48. Hu Y, Cao PP, Liang GT, et al. Diagnostic significance of blood eosinophil count in eosinophilic chronic rhinosinusitis with nasal polyps in Chinese adults. Laryngoscope 2012; 122:498-503.
49. Armengot M, Garin L, de Lamo M, et al. Cytological and tissue eosinophilia correlations in nasal polyposis. Am J Rhinol Allergy 2010; 24:413-415.
50. Leung RM, Kern RC, Conley DB, et al. Osteomeatal complex obstruction is not associated with adjacent sinus disease in chronic rhinosinusitis with polyps. Am J Rhinol Allergy 2011; 25:401-403.
51. Snidvongs K CD, Sacks R, Earls P, Harvey RJ. Eosinophilic rhinosinusitis is not a disease of ostiomeatal occlusion. Laryngoscope 2012; (in press).
52. Snidvongs K, Chaowanapanja P, Aeumjaturapat S, et al. Does nasal irrigation enter paranasal sinuses in chronic rhinosinusitis? Am J Rhinol 2008; 22:483-486.
53. Harvey RJ, Debnath N, Srubiski A, et al. Fluid residuals and drug exposure in nasal irrigation. Otolaryngol Head Neck Surg 2009; 141:757-761.
54. Harvey RJ, Goddard JC, Wise SK, Schlosser RJ. Effects of endoscopic sinus surgery and delivery device on cadaver sinus irrigation. Otolaryngol Head Neck Surg 2008; 139:137-142.
55. Snidvongs K KL, Sivasubramaniam R, Cope D, et al. Topical steroid for nasal polyps. Cochrane Database Syst Rev 2012; (in press).
56. Grobler A, Weitzel EK, Buele A, et al. Pre and postoperative sinus penetration of nasal irrigation. Laryngoscope 2008; 118:2078-2081.
57. Brenner PS, Abadie WM, Weitzel EK, et al. Unexpected consequences of transnasal balloon dilation of the maxillary ostium. Int Forum Allergy Rhinol 2011; 1:466-470.
58. Harvey RJ, Schlosser RJ. Local drug delivery. Otolaryngol Clin North Am 2009; 42:829-845; ix..
59. Chalton R, Mackay I, Wilson R, Cole P. Double blind, placebo controlled trial of betamethasone nasal drops for nasal polyposis. Br Med J 1985; 291:788.
60. Snidvongs K, Pratt E, Chin D, et al. Corticosteroid nasal irrigations after endoscopic sinus surgery in the management of chronic rhinosinusitis. Int Forum Allergy Rhinol 2012; 2:415-421.