Decreased expression of FOXP3 in nasal polyposis

Allergy, Asthma and Immunology Research

Volumn 4, Issue 1, 2012, Pages 24-30

  Roongrotwattanasiri, Kannika ^a,b   Pawankar, Ruby ^a   Kimura, Satoko ^a   Mori, Sachiko ^a   Nonaka, Manabu ^a   Yagi, Toshiaki ^a  

^a NIPPON MEDICAL SCHOOL   (Japan)

^b Faculty of Medicine Chiang Mai University   (Thailand)

Author keywords

Foxp3; Ige; Inflammation; Nasal polyposis; Regulatory T cells; Th2

Indexed keywords

EOTAXIN; MACROPHAGE DERIVED CHEMOKINE; RANTES; THYMUS AND ACTIVATION REGULATED CHEMOKINE; TRANSCRIPTION FACTOR FOXP3;

ADULT; ALLERGIC RHINITIS; ARTICLE; ATOPY; CD4+ CD25+ T LYMPHOCYTE; CD4+ T LYMPHOCYTE; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; EOSINOPHIL; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; INFLAMMATION; LAMINA PROPRIA; LYMPHOCYTE COUNT; MAST CELL; NOSE MUCOSA; NOSE POLYP; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; RHINOSINUSITIS; TH2 CELL;

EID: 83755182869     PISSN: 20927355     EISSN: 20927363     Source Type: Journal    
DOI: 10.4168/aair.2012.4.1.24     Document Type: Article

References (25)

1. Pearlman AN, Chandra RK, Chang D, Conley DB, Tripathi-Peters A, Grammer LC, Schleimer RT, Kern RC. Relationships between severity of chronic rhinosinusitis and nasal polyposis, asthma, and atopy. Am J Rhinol Allergy 2009;23:145-8.
2. Pawankar R, Nonaka M. Inflammatory mechanisms and remodeling in chronic rhinosinusitis and nasal polyps. Curr Allergy Asthma Rep 2007;7:202-8
3. Sánchez-Segura A, Brieva JA, Rodríguez C. T lymphocytes that infiltrate nasal polyps have a specialized phenotype and produce a mixed TH1/TH2 pattern of cytokines. J Allergy Clin Immunol 1998;102:953-60.
4. Hamilos DL, Leung DY, Huston DP, Kamil A, Wood R, Hamid Q. GM-CSF, IL-5 and RANTES immunoreactivity and mRNA expression in chronic hyperplastic sinusitis with nasal polyposis (NP). Clin Exp Allergy 1998;28:1145-52.
5. Patou J, Gevaert P, Van Zele T, Holtappels G, van Cauwenberge P, Bachert C. Staphylococcus aureus enterotoxin B, protein A, and lipoteichoic acid stimulations in nasal polyps. J Allergy Clin Immunol 2008;121:110-5.
6. Fukumoto A, Nonaka M, Ogihara N, Pawankar R. Induction of TARC production by lipopolysaccharide and interleukin-4 in nasal fibroblasts. Int Arch Allergy Immunol 2008;145:291-7.
7. Bernstein JM, Allen C, Rich G, Dryja D, Bina P, Reiser R, Ballow M, Wilding GE. Further observations on the role of Staphylococcus aureus exotoxins and IgE in the pathogenesis of nasal polyposis. Laryngoscope 2011;121:647-55.
8. Kimura S, Pawankar R, Mori S, Nonaka M, Masuno S, Yagi T, Okubo K. Increased expression and role of thymic stromal lymphopoietin in nasal polyposis. Allergy Asthma Immunol Res 2011;3:186-93.
9. Ling Y, Cao XS, Yu ZQ, Luo GH, Bai X, Su J, Dai L, Ruan CG. Alterations of CD4+ CD25+ regulatory T cells in patients with idiopathic thrombocytopenic purpura. Zhonghua Xue Ye Xue Za Zhi 2007;28:184-8.
10. Pekiner FN, Demirel GY, Gümrü B, Ozbayrak S. Serum cytokine and T regulatory cell levels in patients with burning mouth syndrome. J Oral Pathol Med 2008;37:528-34.
11. Wang J, Zhao R, Zhang F, Li J, Huo B, Cao Y, Dou K. Control of allograft rejection in mice by applying a novel neuropeptide, cortistatin. Adv Ther 2008;25:1331-41.
12. Provoost S, Maes T, van Durme YM, Gevaert P, Bachert C, Schmidt-Weber CB, Brusselle GG, Joos GF, Tournoy KG. Decreased FOXP3 protein expression in patients with asthma. Allergy 2009;64:1539-46.
13. Paik Y, Dahl M, Fang D, Calhoun K. Update: the role of FoxP3 in allergic disease. Curr Opin Otolaryngol Head Neck Surg 2008;16:275-9.
14. Feuerer M, Hill JA, Mathis D, Benoist C. Foxp3+ regulatory T cells: differentiation, specification, subphenotypes. Nat Immunol 2009;10:689-95.
15. Dutsch-Wicherek M, Tomaszewska R, Lazar A, Strek P, Wicherek L, Kijowski J, Majka M. The presence of B7-H4+ macrophages and CD25+CD4+ and FOXP3+ regulatory T cells in the microenvironment of nasal polyps - a preliminary report. Folia Histochem Cytobiol 2010;48:611-7.
16. Mason DY, Sammons R. Alkaline phosphatase and peroxidase for double immunoenzymatic labelling of cellular constituents. J Clin Pathol 1978;31:454-60.
17. Curotto de Lafaille MA, Kutchukhidze N, Shen S, Ding Y, Yee H, Lafaille JJ. Adaptive Foxp3+ regulatory T cell-dependent and -independent control of allergic inflammation. Immunity 2008;29:114-26.
18. Lee JH, Yu HH, Wang LC, Yang YH, Lin YT, Chiang BL. The levels of CD4+CD25+ regulatory T cells in paediatric patients with allergic rhinitis and bronchial asthma. Clin Exp Immunol 2007;148:53-63.
19. Van Zele T, Gevaert P, Watelet JB, Claeys G, Holtappels G, Claeys C, van Cauwenberge P, Bachert C. Staphylococcus aureus colonization and IgE antibody formation to enterotoxins is increased in nasal polyposis. J Allergy Clin Immunol 2004;114:981-3.
20. Suh KS, Park HS, Nahm DH, Kim YK, Lee YM, Park K. Role of IgG, IgA, and IgE antibodies in nasal polyp tissue: their relationships with eosinophilic infiltration and degranulation. J Korean Med Sci 2002;17:375-80.
21. Mandron M, Ariès MF, Brehm RD, Tranter HS, Acharya KR, Charveron M, Davrinche C.. Human dendritic cells conditioned with Staphylococcus aureus enterotoxin B promote TH2 cell polarization. J Allergy Clin Immunol 2006;117:1141-7.
22. Van Bruaene N, Pérez-Novo CA, Basinski TM, Van Zele T, Holtappels G, De Ruyck N, Schmidt-Weber C, Akdis C, Van Cauwenberge P, Bachert C, Gevaert P. T-cell regulation in chronic paranasal sinus disease. J Allergy Clin Immunol 2008;121:1435-41, 1441.e1-3.
23. Pérez Novo CA, Jedrzejczak-Czechowicz M, Lewandowska-Polak A, Claeys C, Holtappels G, Van Cauwenberge P, Kowalski ML, Bachert C. T cell inflammatory response, Foxp3 and TNFRS18-L regulation of peripheral blood mononuclear cells from patients with nasal polyps-asthma after staphylococcal superantigen stimulation. Clin Exp Allergy 2010;40:1323-32.
24. Bernstein JM, Ballow M, Rich G, Allen C, Swanson M, Dmochowski J. Lymphocyte subpopulations and cytokines in nasal polyps: is there a local immune system in the nasal polyp? Otolaryngol Head Neck Surg 2004;130:526-35.
25. Pawankar R. Nasal polyposis: an update: editorial review. Curr Opin Allergy Clin Immunol 2003;3:1-6.