Lesions masquerading as acute stroke

Journal of Magnetic Resonance Imaging

Volumn 37, Issue 1, 2013, Pages 15-34

  Liu, Xiang ^a   Almast, Jeevak ^a   Ekholm, Sven ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

acute stroke; CT; diffusion weighted imaging; MRI; perfusion weighted imaging; stroke mimics

Indexed keywords

BRAIN DISEASE; CEREBRAL HYPERPERFUSION SYNDROME; CEREBROVASCULAR ACCIDENT; CEREBROVASCULAR MALFORMATION; COMPUTER ASSISTED TOMOGRAPHY; CONTRAST ENHANCEMENT; CREUTZFELDT JAKOB DISEASE; DEMYELINATING DISEASE; DIFFUSION WEIGHTED IMAGING; DRUG ABUSE; GLIOBLASTOMA; HEPATIC ENCEPHALOPATHY; HERPES SIMPLEX ENCEPHALITIS; HUMAN; HYPERGLYCEMIA; HYPOGLYCEMIA; INFECTION; INTRACRANIAL TUMOR; LEUKOENCEPHALOPATHY; MELAS SYNDROME; MENINGIOMA; METABOLIC DISORDER; MULTIPLE SCLEROSIS; NERVE DEGENERATION; NEUROIMAGING; NUCLEAR MAGNETIC RESONANCE IMAGING; PERFUSION WEIGHTED IMAGING; POSTERIOR REVERSIBLE ENCEPHALOPATHY SYNDROME; PRIORITY JOURNAL; PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY; REVIEW; SEIZURE; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; STROKE LIKE MIGRAINE ATTACKS AFTER RADIATION TREATMENT; SUBDURAL HEMATOMA; VEIN THROMBOSIS;

ACUTE DISEASE; ALGORITHMS; BRAIN; BRAIN MAPPING; BRAIN NEOPLASMS; DIAGNOSIS, DIFFERENTIAL; DIAGNOSTIC IMAGING; DIFFUSION MAGNETIC RESONANCE IMAGING; GLIOMA; HUMANS; MENINGIOMA; NEOPLASM METASTASIS; PERFUSION; STROKE; TOMOGRAPHY, X-RAY COMPUTED; VENOUS THROMBOSIS;

EID: 84872846162     PISSN: 10531807     EISSN: 15222586     Source Type: Journal    
DOI: 10.1002/jmri.23647     Document Type: Review

References (99)

1. Lloyd-Jones D, Adams RJ, Brown TM, et al. Heart disease and stroke statistics-2010 update: a report from the American Heart Association. Circulation 2010; 121: e46-e215.
2. Huff JS,. Stroke mimics and chameleons. Emerg Med Clin North Am 2002; 20: 583-595.
3. Norris JW, Hachinski VC,. Misdiagnosis of stroke. Lancet 1982; 1: 328-331.
4. Libman RB, Wirkowski E, Alvir J, et al. Conditions that mimic stroke in the emergency department. Implications for acute stroke trials. Arch Neurol 1995; 52: 1119-1122.
5. Allder SJ, Moody AR, Martel AL, et al. Limitations of clinical diagnosis in acute stroke. Lancet 1999; 354: 1523.
6. Hemmen TM, Meyer BC, McClean TL, et al. Identification of nonischemic stroke mimics among 411 code strokes at the University of California, San Diego, Stroke Center. J Stroke Cerebrovasc Dis 2008; 17: 23-25.
7. Hand PJ, Kwan J, Lindley RI, et al. Distinguishing between stroke and mimic at the bedside. The Brain Attack Study. Stroke 2006; 37: 769-775.
8. Hatzitolios A, Savopoulos C, Ntaios G, et al. Stroke and conditions that mimic it: a protocol secures a safe early recognition. Hippokratia 2008; 12: 98-102.
9. Scott PA, Silbergleit R,. Misdiagnosis of stroke in tissue plasminogen activator-treated patients: characteristics and outcomes. Ann Emerg Med 2003; 42: 611-618.
10. Winkler DT, Fluri F, Fuhr P, et al. Thrombolysis in stroke mimics: frequency, clinical characteristics, and outcome. Stroke 2009; 40: 1522-1525.
11. Garcia, AM, Egido JA, Garcia ME, et al. Thrombolysis for ischaemic stroke and glioblastoma multiforme: a case report. BMJ Case Rep 2009 [Epub ahead of print].
12. Chernyshev OY, Martin-Schild S, Albright KC, et al. Safety of tPA in stroke mimics and neuroimaging-negative cerebral ischemia. Neurology 2010; 74: 1340-1345.
13. Tsivgoulis G, Alexandrov AV, Chang J, et al. Safety and outcomes of intravenous thrombolysis in stroke mimics: a 6-year, single-care center study and a pooled analysis of reported series. Stroke 2011; 42: 1771-1774.
14. Chen Y, Bogosavljevic V, Leys D, et al. Intravenous thrombolytic therapy in patients with stroke mimics: baseline characteristics and safety profile. Eur J Neurol 2011; 18: 1246-1250.
15. Taylor CL, Selman WR, Ratcheson RA,. Steal affecting the central nervous system. Neurosurgery 2002; 50: 679-688
16. van Mook WN, Rennenberg RJ, Schurink GW, et al. Cerebral hyperperfusion syndrome. Lancet Neurol 2005; 4: 877-888.
17. Adhiyaman V, Alexander S,. Cerebral hyperperfusion syndrome following carotid endarterectomy. QJM 2007; 100: 239-244.
18. Tseng YC, Hsu HL, Lee TH, et al. Prediction of cerebral hyperperfusion syndrome after carotid stenting: a cerebral perfusion computed tomography study. J Comput Assist Tomogr 2009; 33: 540-545.
19. Bousser MG, Ferro JM,. Cerebral venous thrombosis: an update. Lancet Neurol 2007; 6: 162-170.
20. Leach JL, Fortuna RB, Jones BV, et al. Imaging of cerebral venous thrombosis: current techniques, spectrum of findings, and diagnostic pitfalls. Radiographics 2006; 26: S19-41.
21. Ross RT,. Transient tumor attacks. Arch Neurol 1983; 40: 633-636.
22. Morgenstern LB, Frankowski RF,. Brain tumor masquerading as stroke. J Neurooncol 1999; 44: 47-52.
23. The UK TIA study group. Intracranial tumors that mimic transient cerebral ischaemia: sessons from a large multicentre trial. J Neurol Neurosurg Psychiatry 1993; 56: 563-536.
24. Komotar RJ, Keswani SC, Wityk RJ,. Meningioma presenting as stroke: report of two cases and estimation of incidence. J Neurol Neurosurg Psychiatry 2003; 74: 136-137.
25. Graus F, Rogers LR, Posner JB,. Cerebrovascular complications in patients with cancer. Medicine 1985; 64: 16-35.
26. Lefkovitz NW, Roessmann U, Kori SH,. Major cerebral infarction from tumor embolus. Stroke 1986; 17: 555-557.
27. O'Neill BP, Dinapoli RP, Okazaki H,. Cerebral Infarction as a result of tumor emboli. Cancer 1987; 16: 90-95.
28. Aoki N, Sakai T, Oikawa A, et al. Dissection of the middle cerebral artery caused by invasion of malignant glioma presenting as acute onset of hemiplegia. Acta Neurochir 1999; 141: 1005-1008.
29. Fisher M, Recht L,. Brain tumor presenting as an acute pure motor hemiparesis. Stroke 1989; 20: 288-291.
30. Rogers LR,. Cerebrovascular complications in cancer patients. Neurol Clin 1991; 9: 889-899.
31. Chaturvedi S, Ansell J, Recht L,. Should cerebral ischemic events in cancer patients be considered a manifestation of hyper coagulability? Stroke 1994; 25: 1215-1218.
32. Cascino TL,. Neurologic complications of systemic cancer. Med Clin N Am 1993; 77: 265-279.
33. Menon B, Vengamma B, Suman R, et al. Glioma masquerading as stroke. JIACM 2010; 11: 302-305.
34. Sharma T, Khosla VK, Brar R,. Primary glioblastoma multiformis of cerebellum mimicking infarct. Neurol India 2010; 58: 808-810.
35. Manara R, Marasco R, Citton V, et al. Gliomatosis cerebri: a possible clinical and neuroradiologic "stroke mimic." Neurologist 2011; 17: 83-85.
36. Nguyen TT, Wray AC, Laidlaw JD,. Midbrain and thalamic haemorrhage as first presentation of intracerebral glioma. J Clin Neurosci 2005; 12: 946-949.
37. Inamasu J, Kuramae T, Nakatsukasa M,. Glioblastoma masquerading as a hypertensive putaminal hemorrhage: a diagnostic pitfall. Neurol Med Chir (Tokyo) 2009; 49: 427-429.
38. Petzold GC, Valdueza JM, Zimmer C,. Cerebral metastasis of renal carcinoma mimicking venous haemorrhagic infarction. J Neurol Neurosurg Psychiatry 2004; 75: 477.
39. Sumer M, Ozon AO, Bakar B, Cila A, Ruacan S,. Intravascular lymphoma masquerading as multiembolic stroke developing after coronary artery by-pass surgery. Neurologist 2009; 15: 98-101.
40. Zimmerman RD, Fleming CA, Saint-Louis LA, et al. Magnetic resonance imaging of meningiomas. AJNR Am J Neuroradiol 1985; 6: 149-157.
41. Schubeus P, Schorner W, Rottacker C, et al. Intracranial meningiomas: how frequent are indicative findings in CT and MRI? Neuroradiology 1990; 32: 467-473.
42. Goldsher D, Litt AW, Pinto RS, et al. Dural "tail" associated with meningiomas on Gd-DTPA-enhanced MR images: characteristics, differential diagnostic value, and possible implications for treatment. Radiology 1990; 176: 447-450.
43. Cha S,. Update on brain tumor imaging: from anatomy to physiology. AJNR Am J Neuroradiol 2006; 27: 475-487.
44. Cha S, Lupo JM, Chen MH, et al. Differentiation of glioblastoma multiforme and single brain metastasis by peak height and percentage of signal intensity recovery derived from dynamic susceptibility-weighted contrast-enhanced perfusion MR imaging. AJNR Am J Neuroradiol 2007; 28: 1078-1084.
45. Law M, Cha S, Knopp EA, et al. High-grade gliomas and solitary metastases: differentiation by using perfusion and proton spectroscopic MR imaging. Radiology 2002; 222: 715-721.
46. Cha S, Knopp EA, Johnson G, Wetzel SG, Litt AW, Zagzag D,. Intracranial mass lesions: dynamic contrast-enhanced susceptibility-weighted echo-planar perfusion MR imaging. Radiology 2002; 223: 11-29.
47. Cha S,. Perfusion MR imaging of brain tumors. Top Magn Reson Imaging 2004; 15: 279-289.
48. Law M, Yang S, Wang H, et al. Glioma grading: sensitivity, specificity, and predictive values of perfusion MR imaging and proton MR spectroscopic imaging compared with conventional MR imaging. AJNR Am J Neuroradiol 2003; 24: 1989-1998.
49. Schrader B, Barth H, Lang EW, et al. Spontaneous intracranial haematomas caused by neoplasms. Acta Neurochir (Wien) 2000; 142: 979-985.
50. Little JR, Dial B, Belanger G, Carpenter S,. Brain hemorrhage from intracranial tumor. Stroke 1979; 10: 238-283.
51. Lieu AS, Hwang SL, Howng SL, Chai CY,. Brain tumors with hemorrhage. J Formos Med Assoc 1999; 98: 365-367.
52. Liu X, Tian W, Kolar B, et al. MR diffusion tensor and perfusion weighted imaging in preoperative grading of supratentorial non-enhancing gliomas. Neurooncology 2011; 13: 447-455.
53. Qiu W, Wu JS, Carroll WM, et al. Wallenberg syndrome caused by multiple sclerosis mimicking stroke. J Clin Neurosci 2009; 16: 1700-1702.
54. Rosso C, Remy P, Creange A, et al. Diffusion-weighted MR imaging characteristics of an acute strokelike form of multiple sclerosis. AJNR Am J Neuroradiol 2006; 27: 1006-1008.
55. Przeklasa-Auth M, Ovbiagele B, Yim C, et al. Multiple sclerosis with initial stroke-like clinicoradiologic features: case report and literature review. Child Neurol 2010; 25: 732-737.
56. Bugnicourt JM, Garcia PY, Monet P, et al. Teaching neuroimages: marked reduced apparent diffusion coefficient in acute multiple sclerosis lesion. Neurology 2010; 74: e87.
57. Malhotra HS, Jain KK, Agarwal A, et al. Characterization of tumefactive demyelinating lesions using MR imaging and in-vivo proton MR spectroscopy. Mult Scler 2009; 15: 193-203.
58. Masdeu JC, Quinto C, Olivera C, et al. Open-ring imaging sign: highly specific for atypical brain demyelination. Neurology 2000; 54: 1427-1433.
59. Mori K, Miwa K, Hara S, et al. [A case of a bacterial brain abscess presenting as symptoms of 'sudden stroke-like' onset]. No Shinkei Geka [in Japanese] 2003; 31: 443-448.
60. Garg RK, Sinha MK,. Multiple ring-enhancing lesions of the brain. J Postgrad Med 2010; 56: 307-316.
61. Leuthardt EC, Wippold FJ 2nd, Oswood MC, et al. Diffusion-weighted MR imaging in the preoperative assessment of brain abscesses. Surg Neurol 2002; 58: 395-402.
62. Karnath B,. Subdural hematoma: presentation and management in older adults. Geriatrics 2004; 58: 18-23.
63. Yokoyama K, Matsuki M, Shimano H, et al. Diffusion tensor imaging in chronic subdural hematoma: correlation between clinical signs and fractional anisotropy in the pyramidal tract. AJNR Am J Neuroradiol 2008; 29: 1159-1163.
64. Zuccoli G, Pipitone N,. Neuroimaging findings in acute Wernicke's encephalopathy: review of the literature. AJR Am J Roentgenol 2009; 192: 501-508.
65. Fei GQ, Zhong C, Jin L, et al. Clinical characteristics and MR imaging features of nonalcoholic Wernicke encephalopathy. AJNR Am J Neuroradiol 2008; 29: 164-169.
66. Hagan IG, Burney K,. Radiology of recreational drug abuse. Radiographics 2007; 27: 919-940.
67. Rovira A, Alonso J, Cõrdoba J,. R imaging findings in hepatic encephalopathy. AJNR Am J Neuroradiol 2008; 29: 1612-1621.
68. Wintermark M, Fischbein NJ, Mukherjee P, et al. Unilateral putaminal CT, MR, and diffusion abnormalities secondary to nonketotic hyperglycemia in the setting of acute neurologic symptoms mimicking stroke. AJNR Am J Neuroradiol 2004; 25: 975-976.
69. Black DF, Bartleson JD, Bell ML, et al. SMART: stroke-like migraine attacks after radiation therapy. Cephalalgia 2006; 26: 1137-1142.
70. Bartleson JD, Krecke KN, O'Neill BP, et al. Reversible, strokelike migraine attacks in patients with previous radiation therapy. J Neurooncol 2003; 5: 121-127.
71. Farid K, Meissner WG, Samier-Foubert A, et al. Normal cerebrovascular reactivity in stroke-like migraine attacks after radiation therapy syndrome. Clin Nucl Med 2010; 35: 583-585.
72. Pruitt A, Dalmau J, Detre J, et al. Episodic neurologic dysfunction with migraine and reversible imaging findings after radiation. Neurology 2006; 67: 676-678.
73. Hinchey J, Chaves C, Appignani B, et al. A reversible posterior leukoencephalopathy syndrome. N Engl J Med 1996; 334: 494-500.
74. Bartynski WS, Boardman JF,. Distinct imaging patterns and lesion distribution in posterior reversible encephalopathy syndrome (PRES). AJNR Am J Neuroradiol 2007; 28: 1320-1327.
75. Bartynski WS,. Posterior reversible encephalopathy syndrome. Part 1. Fundamental imaging and clinical features. AJNR Am J Neuroradiol 2008; 29: 1036-1042.
76. Wu Q, Marescaux C, Wolff V, et al. Tacrolimus-associated posterior reversible encephalopathy syndrome after solid organ transplantation. Eur Neurol 2010; 64: 169-177.
77. Cole AJ,. Status epilepticus and periictal imaging. Epilepsia 2004; 45 (Suppl 4): 72-77.
78. Huang YC, Weng HH, Tsai YT, et al. Periictal magnetic resonance imaging in status epilepticus. Epilepsy Res 2009; 86: 72-81.
79. Craven I, Kotsarini C, Hoggard N,. Recent advances in imaging epilepsy. Postgrad Med J 2010; 86: 552-559.
80. Wiest R, von Bredow F, Schindler K, et al. Detection of regional blood perfusion changes in epileptic seizures with dynamic brain perfusion CT-a pilot study. Epilepsy Res 2006; 72: 102-110.
81. Gelfand JM, Wintermark M, Josephson SA,. Cerebral perfusion-CT patterns following seizure. Eur J Neurol 2010; 17: 594-601.
82. Mathews MS, Smith WS, Wintermark M, et al. Local cortical hypoperfusion imaged with CT perfusion during postictal Todd's paresis. Neuroradiology 2008; 50: 397-401.
83. Parmar H, Lim SH, Tan NC, et al. Acute symptomatic seizures and hippocampus damage: DWI and MRS findings. Neurology 2006; 66: 1732-1735.
84. Hauf M, Slotboom J, Nirkko A, et al. Cortical regional hyperperfusion in nonconvulsive status epilepticus measured by dynamic brain perfusion CT. AJNR Am J Neuroradiol 2009; 30: 693-698.
85. Royter V, Paletz L, Waters MF,. Stroke vs. status epilepticus. A case report utilizing CT perfusion. J Neurol Sci 2008; 266: 174-176.
86. Masterson K, Vargas MI, Delavelle J,. Postictal deficit mimicking stroke: role of perfusion CT. J Neuroradiol 2009; 36: 48-51.
87. Szabo K, Poepel A, Pohlmann-Eden B, et al. Diffusion-weighted and perfusion MRI demonstrates parenchymal changes in complex partial status epilepticus. Brain 2005; 128: 1369-1376.
88. Leonhardt G, de Greiff A, Weber J, et al. Brain perfusion following single seizures. Epilepsia 2005; 46: 1943-1949.
89. El-Koussy M, Mathis J, Lovblad KO, et al. Focal status epilepticus: follow-up by perfusion and diffusion MRI. Eur Radiol 2002; 12: 568-574.
90. Kim JA, Chung JI, Yoon PH, et al. Transient MR signal changes in patients with generalized tonicoclonic seizure or status epilepticus: periictal diffusion-weighted imaging. AJNR Am J Neuroradiol 2001; 22: 1149-1160.
91. Liu X, Tian W, Li L, et al. Hyperintensity on diffusion weighted image along ipsilateral cortical spinal tract after cerebral ischemic stroke: a diffusion tensor analysis. Eur J Radiol 2012; 81: 292-297.
92. Castillo M, Mukherji SK,. Early abnormalities related to postinfarction Wallerian degeneration: evaluation with MR diffusion-weighted imaging. J Comput Assist Tomogr 1999; 23: 1004-1007.
93. Vitali P, Maccagnano E, Caverzasi E, et al. Diffusion-weighted MRI hyperintensity patterns differentiate CJD from other rapid dementias. Neurology 2011; 76: 1711-1719.
94. Shah R, Bag AK, Chapman PR, et al. Imaging manifestations of progressive multifocal leukoencephalopathy. Clin Radiol 2010; 65: 431-439.
95. Ametani M, Ogawa T, Tanabe Y, et al. Sequential MR imaging and SPECT studies in herpes simplex encephalitis with crossed cerebellar hyperperfusion. Ann Nucl Med 2005; 19: 151-155.
96. Küker W, Nägele T, Schmidt F, et al. Diffusion-weighted MRI in herpes simplex encephalitis: a report of three cases. Neuroradiology 2004; 46: 122-125.
97. Ma JH, Kim YJ, Yoo WJ, et al. MR imaging of hypoglycemic encephalopathy: lesion distribution and prognosis prediction by diffusion-weighted imaging. Neuroradiology 2009; 51: 641-649.
98. Ohshita T, Oka M, Imon Y, et al. Serial diffusion-weighted imaging in MELAS. Neuroradiology 2000; 42: 651-656.
99. Rosen L, Phillips S, Enzmann D,. Magnetic resonance imaging in MELAS syndrome. Neuroradiology 1990; 32: 168-171.