Retraction: Diabetes and overexpression of proNGF cause retinal neurodegeneration via activation of RhoA pathway (PLoS ONE (2013) 8:1 (e54692) DOI: 10.1371/journal.pone.0054692);Diabetes and Overexpression of proNGF Cause Retinal Neurodegeneration via Activation of RhoA Pathway

PLoS ONE

Volumn 8, Issue 1, 2013, Pages

  Al Gayyar, Mohammed M H ^a,b,c,d   Mysona, Barbara A ^a,b,c   Matragoon, Suraporn ^a,b,c   Abdelsaid, Mohammed A ^a,b,c   El Azab, Mona F ^a,b,c,e   Shanab, Ahmed Y ^a,b,c   Ha, Yonju ^b   Smith, Sylvia B ^b   Bollinger, Kathryn E ^b   El Remessy, Azza B ^a,b,c  

^a UNIVERSITY OF GEORGIA   (United States)

^b MEDICAL COLLEGE OF GEORGIA   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

^d MANSOURA UNIVERSITY   (Egypt)

^e SUEZ CANAL UNIVERSITY   (Egypt)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; JANUS KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; NERVE GROWTH FACTOR; NEUROTROPHIN RECEPTOR P75; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PRONERVE GROWTH FACTOR; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DEATH; CONTROLLED STUDY; DIABETES MELLITUS; DISEASE ASSOCIATION; ENZYME ACTIVATION; IN VITRO STUDY; IN VIVO STUDY; MALE; MOLECULAR DYNAMICS; MOLECULAR PATHOLOGY; NICK END LABELING; NONHUMAN; PROTEIN CLEAVAGE; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; RETINA DEGENERATION; RETINA GANGLION CELL; SIGNAL TRANSDUCTION; UPREGULATION; WESTERN BLOTTING;

EID: 84872844805     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0186748     Document Type: Erratum

References (45)

1. Al-Gayyar MMH, Matragoon S, Pillai BA, Ali TK, Abdelsaid MA, et al. (2011) Epicatechin blocks proNGF-mediated retinal neurodegeneration via inhibition of p75NTR expression in experimental diabetes. Diabetologia.
2. Ali TK, Al-Gayyar MM, Matragoon S, Pillai BA, Abdelsaid MA, et al. (2011) Diabetes-induced peroxynitrite impairs the balance of pro-nerve growth factor and nerve growth factor, and causes neurovascular injury. Diabetologia.
3. Casaccia-Bonnefil P, Carter BD, Dobrowsky RT, Chao MV, (1996) Death of oligodendrocytes mediated by the interaction of nerve growth factor with its receptor p75. Nature 383: 716-719.
4. von Bartheld CS, (1998) Neurotrophins in the developing and regenerating visual system. Histol Histopathol 13: 437-459.
5. Fahnestock M, Yu G, Michalski B, Mathew S, Colquhoun A, et al. (2004) The nerve growth factor precursor proNGF exhibits neurotrophic activity but is less active than mature nerve growth factor. J Neurochem 89: 581-592.
6. Masoudi R, Ioannou MS, Coughlin MD, Pagadala P, Neet KE, et al. (2009) Biological activity of nerve growth factor precursor is dependent upon relative levels of its receptors. J Biol Chem 284: 18424-18433.
7. Ali TK, Matragoon S, Pillai BA, Liou GI, El-Remessy AB, (2008) Peroxynitrite mediates retinal neurodegeneration by inhibiting NGF survival signal in experimental and human diabetes. J Diabetes 57: 889-898.
8. Yune TY, Lee JY, Jung GY, Kim SJ, Jiang MH, et al. (2007) Minocycline alleviates death of oligodendrocytes by inhibiting pro-nerve growth factor production in microglia after spinal cord injury. J Neurosci 27: 7751-7761.
9. Semenova MM, Maki-Hokkonen AM, Cao J, Komarovski V, Forsberg KM, et al. (2007) Rho mediates calcium-dependent activation of p38alpha and subsequent excitotoxic cell death. Nat Neurosci 10: 436-443.
10. Dubreuil CI, Winton MJ, McKerracher L, (2003) Rho activation patterns after spinal cord injury and the role of activated Rho in apoptosis in the central nervous system. J Cell Biol 162: 233-243.
11. Nwariaku FE, Chang J, Zhu X, Liu Z, Duffy SL, et al. (2002) The role of p38 map kinase in tumor necrosis factor-induced redistribution of vascular endothelial cadherin and increased endothelial permeability. Shock 18: 82-85.
12. Nwariaku FE, Rothenbach P, Liu Z, Zhu X, Turnage RH, et al. (2003) Rho inhibition decreases TNF-induced endothelial MAPK activation and monolayer permeability. J Appl Physiol 95: 1889-1895.
13. Arthur WT, Noren NK, Burridge K, (2002) Regulation of Rho family GTPases by cell-cell and cell-matrix adhesion. Biol Res 35: 239-246.
14. Burridge K, Wennerberg K, (2004) Rho and Rac take center stage. Cell 116: 167-179.
15. Huang EJ, Reichardt LF, (2003) Trk receptors: roles in neuronal signal transduction. Annu Rev Biochem 72: 609-642.
16. Linseman DA, Loucks FA, (2008) Diverse roles of Rho family GTPases in neuronal development, survival, and death. Front Biosci 13: 657-676.
17. Miloso M, Scuteri A, Foudah D, Tredici G, (2008) MAPKs as mediators of cell fate determination: an approach to neurodegenerative diseases. Curr Med Chem 15: 538-548.
18. Kawasaki H, Morooka T, Shimohama S, Kimura J, Hirano T, et al. (1997) Activation and involvement of p38 mitogen-activated protein kinase in glutamate-induced apoptosis in rat cerebellar granule cells. J Biol Chem 272: 18518-18521.
19. Kummer JL, Rao PK, Heidenreich KA, (1997) Apoptosis induced by withdrawal of trophic factors is mediated by p38 mitogen-activated protein kinase. J Biol Chem 272: 20490-20494.
20. Xia Z, Dickens M, Raingeaud J, Davis RJ, Greenberg ME, (1995) Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis. Science 270: 1326-1331.
21. Mielke K, Damm A, Yang DD, Herdegen T, (2000) Selective expression of JNK isoforms and stress-specific JNK activity in different neural cell lines. Brain Res Mol Brain Res 75: 128-137.
22. Irving EA, Barone FC, Reith AD, Hadingham SJ, Parsons AA, (2000) Differential activation of MAPK/ERK and p38/SAPK in neurones and glia following focal cerebral ischaemia in the rat. Brain Res Mol Brain Res 77: 65-75.
23. Matragoon S, Al-Gayyar M, Mysona B, Abdelsaid M, Pillai BA, et al. (2012) Electroporation-mediated gene delivery of cleavage-resistant pro-nerve growth factor causes retinal neuro- and vascular degeneration. Molecular Vision 18: 2993-3003.
24. Dun Y, Thangaraju M, Prasad P, Ganapathy V, Smith SB, (2007) Prevention of excitotoxicity in primary retinal ganglion cells by (+)-pentazocine, a sigma receptor-1 specific ligand. Invest Ophthalmol Vis Sci 48: 4785-4794.
25. Shanab AY, Nakazawa T, Ryu M, Tanaka Y, Himori N, et al. (2012) Metabolic stress response implicated in diabetic retinopathy: The role of calpain, and the therapeutic impact of calpain inhibitor. Neurobiol Dis 48: 556-567.
26. Krishnamoorthy RR, Agarwal P, Prasanna G, Vopat K, Lambert W, et al. (2001) Characterization of a transformed rat retinal ganglion cell line. Brain Res Mol Brain Res 86: 1-12.
27. Al-Gayyar MM, Abdelsaid MA, Matragoon S, Pillai BA, El-Remessy AB, (2010) Neurovascular protective effect of FeTPPs in N-methyl-D-aspartate model: similarities to diabetes. Am J Pathol 177: 1187-1197.
28. El-Remessy AB, Tawfik HE, Matragoon S, Pillai B, Caldwell RB, et al. (2010) Peroxynitrite mediates diabetes-induced endothelial dysfunction: possible role of rho kinase activation. Exp Diabetes Res 2010: 247861.
29. Lebrun-Julien F, Bertrand MJ, De Backer O, Stellwagen D, Morales CR, et al. (2010) ProNGF induces TNFalpha-dependent death of retinal ganglion cells through a p75NTR non-cell-autonomous signaling pathway. Proc Natl Acad Sci U S A 107: 3817-3822.
30. Mysona BA, Abdelsaid MA, Matragoon S, Pillai B, El-Remessy A, (2012) Inflammatory Role of ProNGF/p75NTR in Muller cells of the Diabetic Retina. ARVO Meeting Abstracts 53: 2003.
31. Hammes HP, Federoff HJ, Brownlee M, (1995) Nerve growth factor prevents both neuroretinal programmed cell death and capillary pathology in experimental diabetes. Mol Med 1: 527-534.
32. Carmignoto G, Comelli MC, Candeo P, Cavicchioli L, Yan Q, et al. (1991) Expression of NGF receptor and NGF receptor mRNA in the developing and adult rat retina. Exp Neurol 111: 302-311.
33. Suzuki A, Nomura S, Morii E, Fukuda Y, Kosaka J, (1998) Localization of mRNAs for trkB isoforms and p75 in rat retinal ganglion cells. J Neurosci Res 54: 27-37.
34. Coassin M, Lambiase A, Sposato V, Micera A, Bonini S, et al. (2008) Retinal p75 and bax overexpression is associated with retinal ganglion cells apoptosis in a rat model of glaucoma. Graefes Arch Clin Exp Ophthalmol 246: 1743-1749.
35. Xu F, Wei Y, Lu Q, Zheng D, Zhang F, et al. (2009) Immunohistochemical localization of sortilin and p75(NTR) in normal and ischemic rat retina. Neurosci Lett 454: 81-85.
36. Hu B, Yip HK, So KF, (1999) Expression of p75 neurotrophin receptor in the injured and regenerating rat retina. Neuroreport 10: 1293-1297.
37. Fujimura M, Usuki F, Kawamura M, Izumo S, (2011) Inhibition of the Rho/ROCK pathway prevents neuronal degeneration in vitro and in vivo following methylmercury exposure. Toxicol Appl Pharmacol 250: 1-9.
38. Hirata A, Inatani M, Inomata Y, Yonemura N, Kawaji T, et al. (2008) Y-27632, a Rho-associated protein kinase inhibitor, attenuates neuronal cell death after transient retinal ischemia. Graefes Arch Clin Exp Ophthalmol 246: 51-59.
39. Ito T, Ohtori S, Hata K, Inoue G, Moriya H, et al. (2007) Rho kinase inhibitor improves motor dysfunction and hypoalgesia in a rat model of lumbar spinal canal stenosis. Spine (Phila Pa 1976) 32: 2070-2075.
40. Rao VP, Epstein DL, (2007) Rho GTPase/Rho kinase inhibition as a novel target for the treatment of glaucoma. BioDrugs 21: 167-177.
41. Lebrun-Julien F, Morquette B, Douillette A, Saragovi HU, Di Polo A, (2009) Inhibition of p75(NTR) in glia potentiates TrkA-mediated survival of injured retinal ganglion cells. Mol Cell Neurosci 40: 410-420.
42. Segain JP, Raingeard de la Bletiere D, Sauzeau V, Bourreille A, Hilaret G, et al. (2003) Rho kinase blockade prevents inflammation via nuclear factor kappa B inhibition: evidence in Crohn's disease and experimental colitis. Gastroenterology 124: 1180-1187.
43. He Y, Xu H, Liang L, Zhan Z, Yang X, et al. (2008) Antiinflammatory effect of Rho kinase blockade via inhibition of NF-kappaB activation in rheumatoid arthritis. Arthritis Rheum 58: 3366-3376.
44. Purves T, Middlemas A, Agthong S, Jude EB, Boulton AJ, et al. (2001) A role for mitogen-activated protein kinases in the etiology of diabetic neuropathy. Faseb J 15: 2508-2514.
45. Dong M, Yan BP, Liao JK, Lam YY, Yip GW, et al. (2010) Rho-kinase inhibition: a novel therapeutic target for the treatment of cardiovascular diseases. Drug Discov Today 15: 622-629.