-
1
-
-
77951026738
-
Clinical practice guidelines for Clostridium difficile infection in adults: 2010 update by the Society for Healthcare Epidemiology of America (SHEA) and the Infectious Diseases Society of America (IDSA)
-
doi:10 .1086/651706
-
Cohen SH, Gerding DN, Johnson S, Kelly CP, Loo VG, McDonald LC, Pepin J, Wilcox MH. 2010. Clinical practice guidelines for Clostridium difficile infection in adults: 2010 update by the Society for Healthcare Epidemiology of America (SHEA) and the Infectious Diseases Society of America (IDSA). Infect. Control Hosp. Epidemiol. 31:431-455. doi:10 .1086/651706.
-
(2010)
Infect. Control Hosp. Epidemiol.
, vol.31
, pp. 431-455
-
-
Cohen, S.H.1
Gerding, D.N.2
Johnson, S.3
Kelly, C.P.4
Loo, V.G.5
McDonald, L.C.6
Pepin, J.7
Wilcox, M.H.8
-
2
-
-
85027958654
-
Treatment of refractory and recurrent Clostridium difficile infection
-
doi:10.1038/nrgastro.2011.59
-
Surawicz CM, Alexander J. 2011. Treatment of refractory and recurrent Clostridium difficile infection. Nat. Rev. Gastroenterol. Hepatol. 8:330-339. doi:10.1038/nrgastro.2011.59.
-
(2011)
Nat. Rev. Gastroenterol. Hepatol.
, vol.8
, pp. 330-339
-
-
Surawicz, C.M.1
Alexander, J.2
-
3
-
-
19344363493
-
Increasing risk of relapse after treatment of Clostridium difficile colitis in Quebec, Canada
-
doi:10.1086/430315
-
Pepin J, Alary ME, Valiquette L, Raiche E, Ruel J, Fulop K, Godin D, Bourassa C. 2005. Increasing risk of relapse after treatment of Clostridium difficile colitis in Quebec, Canada. Clin. Infect. Dis. 40:1591-1597. doi:10.1086/430315.
-
(2005)
Clin. Infect. Dis.
, vol.40
, pp. 1591-1597
-
-
Pepin, J.1
Alary, M.E.2
Valiquette, L.3
Raiche, E.4
Ruel, J.5
Fulop, K.6
Godin, D.7
Bourassa, C.8
-
4
-
-
0026663447
-
Treatment of asymptomatic Clostridium difficile carriers (fecal excretors) with vancomycin or metronidazole. A randomized, placebo-controlled trial
-
Johnson S, Homann SR, Bettin KM, Quick JN, Clabots CR, Peterson LR, Gerding DN. 1992. Treatment of asymptomatic Clostridium difficile carriers (fecal excretors) with vancomycin or metronidazole. A randomized, placebo-controlled trial. Ann. Intern. Med. 117:297-302.
-
(1992)
Ann. Intern. Med.
, vol.117
, pp. 297-302
-
-
Johnson, S.1
Homann, S.R.2
Bettin, K.M.3
Quick, J.N.4
Clabots, C.R.5
Peterson, L.R.6
Gerding, D.N.7
-
5
-
-
33747603490
-
Prospective, randomized inpatient study of oral metronidazole versus oral metronidazole and rifampin for treatment of primary episode of Clostridium difficile-associated diarrhea
-
doi:10.1086 /506354
-
Lagrotteria D, Holmes S, Smieja M, Smaill F, Lee C. 2006. Prospective, randomized inpatient study of oral metronidazole versus oral metronidazole and rifampin for treatment of primary episode of Clostridium difficile-associated diarrhea. Clin. Infect. Dis. 43:547-552. doi:10.1086 /506354.
-
(2006)
Clin. Infect. Dis.
, vol.43
, pp. 547-552
-
-
Lagrotteria, D.1
Holmes, S.2
Smieja, M.3
Smaill, F.4
Lee, C.5
-
6
-
-
19344364596
-
Relatively poor outcome after treatment of Clostridium difficile colitis with metronidazole
-
doi: 10.1086/430311
-
Musher DM, Aslam S, Logan N, Nallacheru S, Bhaila I, Borchert F, Hamill RJ. 2005. Relatively poor outcome after treatment of Clostridium difficile colitis with metronidazole. Clin. Infect. Dis. 40:1586-1590. doi: 10.1086/430311.
-
(2005)
Clin. Infect. Dis.
, vol.40
, pp. 1586-1590
-
-
Musher, D.M.1
Aslam, S.2
Logan, N.3
Nallacheru, S.4
Bhaila, I.5
Borchert, F.6
Hamill, R.J.7
-
7
-
-
34547133720
-
A comparison of vancomycin and metronidazole for the treatment of Clostridium difficile-associated diarrhea, stratified by disease severity
-
Zar FA, Bakkanagari SR, Moorthi KM, Davis MB. 2007. A comparison of vancomycin and metronidazole for the treatment of Clostridium difficile-associated diarrhea, stratified by disease severity. Clin. Infect. Dis. 45:302-307.
-
(2007)
Clin. Infect. Dis.
, vol.45
, pp. 302-307
-
-
Zar, F.A.1
Bakkanagari, S.R.2
Moorthi, K.M.3
Davis, M.B.4
-
8
-
-
79551527297
-
Fidaxomicin versus vancomycin for Clostridium difficile infection
-
doi:10.1056 /NEJMoa0910812
-
Louie TJ, Miller MA, Mullane KM, Weiss K, Lentnek A, Golan Y, Gorbach S, Sears P, Shue YK. 2011. Fidaxomicin versus vancomycin for Clostridium difficile infection. N. Engl. J. Med. 364:422-431. doi:10.1056 /NEJMoa0910812.
-
(2011)
N. Engl. J. Med.
, vol.364
, pp. 422-431
-
-
Louie, T.J.1
Miller, M.A.2
Mullane, K.M.3
Weiss, K.4
Lentnek, A.5
Golan, Y.6
Gorbach, S.7
Sears, P.8
Shue, Y.K.9
-
9
-
-
62249214077
-
Rifaximin in treatment of recurrent Clostridium difficile-associated diarrhea: An uncontrolled pilot study
-
doi:10.1097/MCG.0b013e31814a4e97
-
Garey KW, Jiang ZD, Bellard A, Dupont HL. 2008. Rifaximin in treatment of recurrent Clostridium difficile-associated diarrhea: An uncontrolled pilot study. J. Clin. Gastroenterol. doi:10.1097/MCG.0b013e31814a4e97.
-
(2008)
J. Clin. Gastroenterol.
-
-
Garey, K.W.1
Jiang, Z.D.2
Bellard, A.3
Dupont, H.L.4
-
10
-
-
34250015914
-
Clostridium difficile colitis that fails conventional metronidazole therapy: Response to nitazoxanide
-
doi:10.1093/jac/dkl553
-
Musher DM, Logan N, Mehendiratta V, Melgarejo NA, Garud S, Hamill RJ. 2007. Clostridium difficile colitis that fails conventional metronidazole therapy: Response to nitazoxanide. J. Antimicrob. Chemother. 59:705-710. doi:10.1093/jac/dkl553.
-
(2007)
J. Antimicrob. Chemother.
, vol.59
, pp. 705-710
-
-
Musher, D.M.1
Logan, N.2
Mehendiratta, V.3
Melgarejo, N.A.4
Garud, S.5
Hamill, R.J.6
-
11
-
-
57249086250
-
A mouse model of Clostridium difficileassociated disease
-
doi:10.1053/j.gastro200809002
-
Chen X, Katchar K, Goldsmith JD, Nanthakumar N, Cheknis A, Gerding DN, Kelly CP. 2008. A mouse model of Clostridium difficileassociated disease. Gastroenterology 135:1984-1992. doi:10.1053/j.gastro .2008.09.002.
-
(2008)
Gastroenterology
, vol.135
, pp. 1984-1992
-
-
Chen, X.1
Katchar, K.2
Goldsmith, J.D.3
Nanthakumar, N.4
Cheknis, A.5
Gerding, D.N.6
Kelly, C.P.7
-
12
-
-
84864383200
-
Amixicile a novel inhibitor of pyruvate:ferredoxin oxidoreductase shows efficacy against clostridium difficile
-
doi:10 .1128/AAC.00360-12
-
Warren CA, OEvan Ballard TE, Kennedy A, Wang X, Riggins M, Olekhnovich I, Warthan M, Kolling GL, Guerrant RL, Macdonald TL, Hoffman PS. 2012. Amixicile, a novel inhibitor of pyruvate:ferredoxin oxidoreductase, shows efficacy against Clostridium difficile in a mouse infection model. Antimicrob. Agents Chemother. 56:4103-4111. doi:10 .1128/AAC.00360-12.
-
(2012)
A Mouse Infection Model. Antimicrob. Agents Chemother
, vol.56
, pp. 4103-4111
-
-
Warren, C.A.1
Oevan Ballard, T.E.2
Kennedy, A.3
Wang, X.4
Riggins, M.5
Olekhnovich, I.6
Warthan, M.7
Kolling, G.L.8
Guerrant, R.L.9
Macdonald, T.L.10
Hoffman, P.S.11
-
13
-
-
78649537405
-
Murine model of Clostridium difficile infection using gnotobiotic aged C57Bl/6 mice and a BI strain
-
Pawlowski SW, Calabrese G, Kolling GL, Freire R, Alcantara Warren C, Liu B, Sartor B, Guerrant RL. 2010. Murine model of Clostridium difficile infection using gnotobiotic aged C57Bl/6 mice and a BI strain. J. Infect. Dis. 202:1708-1712.
-
(2010)
J. Infect. Dis.
, vol.202
, pp. 1708-1712
-
-
Pawlowski, S.W.1
Calabrese, G.2
Kolling, G.L.3
Freire, R.4
Alcantara Warren, C.5
Liu, B.6
Sartor, B.7
Guerrant, R.L.8
-
14
-
-
54249110955
-
Development of a real-time PCR method for Firmicutes and Bacteroidetes in faeces and its application to quantify intestinal population of obese and lean pigs
-
doi:10.1111/j.1472-765X.2008.02408.x
-
Guo X, Xia X, Tang R, Zhou J, Zhao H, Wang K. 2008. Development of a real-time PCR method for Firmicutes and Bacteroidetes in faeces and its application to quantify intestinal population of obese and lean pigs. Lett. Appl. Microbiol. 47:367-373. doi:10.1111/j.1472-765X.2008.02408.x.
-
(2008)
Lett. Appl. Microbiol.
, vol.47
, pp. 367-373
-
-
Guo, X.1
Xia, X.2
Tang, R.3
Zhou, J.4
Zhao, H.5
Wang, K.6
-
15
-
-
0021156930
-
Bacteroides of the human lower intestinal tract
-
doi101146/annurevmi38100184001453
-
Salyers AA. 1984. Bacteroides of the human lower intestinal tract. Annu. Rev. Microbiol. 38:293-313. doi:10.1146/annurev.mi.38.100184.001453.
-
(1984)
Annu Rev Microbiol
, vol.38
, pp. 293-313
-
-
Salyers, A.A.1
-
16
-
-
66949167421
-
Intravenous tigecycline as adjunctive or alternative therapy for severe refractory Clostridium difficile infection
-
doi:10.1086 /599224
-
Herpers BL, Vlaminckx B, Burkhardt O, Blom H, Biemond-Moeniralam HS, Hornef M, Welte T, Kuijper EJ. 2009. Intravenous tigecycline as adjunctive or alternative therapy for severe refractory Clostridium difficile infection. Clin. Infect. Dis. 48:1732-1735. doi:10.1086 /599224.
-
(2009)
Clin. Infect. Dis.
, vol.48
, pp. 1732-1735
-
-
Herpers, B.L.1
Vlaminckx, B.2
Burkhardt, O.3
Blom, H.4
Biemond-Moeniralam, H.S.5
Hornef, M.6
Welte, T.7
Kuijper, E.J.8
-
17
-
-
33847630925
-
Interruption of recurrent Clostridium difficile-associated diarrhea episodes by serial therapy with vancomycin and rifaximin
-
doi:10.1086/511870
-
Johnson S, Schriever C, Galang M, Kelly CP, Gerding DN. 2007. Interruption of recurrent Clostridium difficile-associated diarrhea episodes by serial therapy with vancomycin and rifaximin. Clin. Infect. Dis. 44:846-848. doi:10.1086/511870.
-
(2007)
Clin. Infect. Dis.
, vol.44
, pp. 846-848
-
-
Johnson, S.1
Schriever, C.2
Galang, M.3
Kelly, C.P.4
Gerding, D.N.5
-
18
-
-
58749112167
-
Nitazoxanide versus vancomycin in Clostridium difficile infection: A randomized, double-blind study
-
doi:10.1086 /596552
-
Musher DM, Logan N, Bressler AM, Johnson DP, Rossignol JF. 2009. Nitazoxanide versus vancomycin in Clostridium difficile infection: A randomized, double-blind study. Clin. Infect. Dis. 48:e41-e46. doi:10.1086 /596552.
-
(2009)
Clin. Infect. Dis.
, vol.48
-
-
Musher, D.M.1
Logan, N.2
Bressler, A.M.3
Johnson, D.P.4
Rossignol, J.F.5
-
19
-
-
0032614375
-
Recurrent Clostridium difficile disease: Epidemiology and clinical characteristics
-
doi:10 .1086/501553
-
McFarland LV, Surawicz CM, Rubin M, Fekety R, Elmer GW, Greenberg RN. 1999. Recurrent Clostridium difficile disease: Epidemiology and clinical characteristics. Infect. Control Hosp. Epidemiol. 20:43-50. doi:10 .1086/501553.
-
(1999)
Infect. Control Hosp. Epidemiol.
, vol.20
, pp. 43-50
-
-
McFarland, L.V.1
Surawicz, C.M.2
Rubin, M.3
Fekety, R.4
Elmer, G.W.5
Greenberg, R.N.6
-
20
-
-
79959413785
-
Mouse relapse model of clostridium difficile infection
-
doi:10.1128/IAI.01336-10
-
Sun X, Wang H, Zhang Y, Chen K, Davis B, Feng H. 2011. Mouse relapse model of Clostridium difficile infection. Infect. Immun. 79:2856-2864. doi:10.1128/IAI.01336-10.
-
(2011)
Infect. Immun.
, vol.79
, pp. 2856-2864
-
-
Sun, X.1
Wang, H.2
Zhang, Y.3
Chen, K.4
Davis, B.5
Feng, H.6
-
21
-
-
34547640095
-
In vitro activities of 15 antimicrobial agents against 110 toxigenic Clostridium difficile clinical isolates collected from 1983 to 2004
-
doi:10.1128/AAC. 01623-06
-
Hecht DW, Galang MA, Sambol SP, Osmolski JR, Johnson S, Gerding DN. 2007. In vitro activities of 15 antimicrobial agents against 110 toxigenic Clostridium difficile clinical isolates collected from 1983 to 2004. Antimicrob. Agents Chemother. 51:2716-2719. doi:10.1128/AAC. 01623-06.
-
(2007)
Antimicrob. Agents Chemother.
, vol.51
, pp. 2716-2719
-
-
Hecht, D.W.1
Galang, M.A.2
Sambol, S.P.3
Osmolski, J.R.4
Johnson, S.5
Gerding, D.N.6
-
22
-
-
60649089055
-
Activity of vancomycin against epidemic Clostridium difficile strains in a human gut model
-
doi:10.1093 /jac/dkn502
-
Baines SD, O'Connor R, Saxton K, Freeman J, Wilcox MH. 2009. Activity of vancomycin against epidemic Clostridium difficile strains in a human gut model. J. Antimicrob. Chemother. 63:520-525. doi:10.1093 /jac/dkn502.
-
(2009)
J. Antimicrob. Chemother.
, vol.63
, pp. 520-525
-
-
Baines, S.D.1
O'Connor, R.2
Saxton, K.3
Freeman, J.4
Wilcox, M.H.5
-
23
-
-
84863641928
-
Fidaxomicin inhibits spore production in Clostridium difficile
-
doi:10.1093/cid/cis453
-
Babakhani F, Bouillaut L, Gomez A, Sears P, Nguyen L, Sonenshein AL. 2012. Fidaxomicin inhibits spore production in Clostridium difficile. Clin. Infect. Dis. 55(Suppl 2):S162-S169. doi:10.1093/cid/cis453.
-
(2012)
Clin. Infect. Dis.
, vol.55
, Issue.SUPPL. 2
-
-
Babakhani, F.1
Bouillaut, L.2
Gomez, A.3
Sears, P.4
Nguyen, L.5
Sonenshein, A.L.6
-
24
-
-
0034628426
-
Asymptomatic carriage of Clostridium difficile and serum levels of IgG antibody against toxin A
-
Kyne L, Warny M, Qamar A, Kelly CP. 2000. Asymptomatic carriage of Clostridium difficile and serum levels of IgG antibody against toxin A. N. Engl. J. Med. 342:390-397.
-
(2000)
N. Engl. J. Med.
, vol.342
, pp. 390-397
-
-
Kyne, L.1
Warny, M.2
Qamar, A.3
Kelly, C.P.4
-
25
-
-
0035915688
-
Association between antibody response to toxin A and protection against recurrent Clostridium difficile diarrhoea
-
doi:10.1016/S01400003592-3
-
Kyne L, Warny M, Qamar A, Kelly CP. 2001. Association between antibody response to toxin A and protection against recurrent Clostridium difficile diarrhoea. Lancet 357:189-193. doi:10.1016/S0140-6736(00)03592-3.
-
(2001)
Lancet
, vol.357
, pp. 189-193
-
-
Kyne, L.1
Warny, M.2
Qamar, A.3
Kelly, C.P.4
-
26
-
-
74849098405
-
Treatment with monoclonal antibodies against Clostridium difficile toxins
-
doi:10.1056/NEJMoa0907635
-
Lowy I, Molrine DC, Leav BA, Blair BM, Baxter R, Gerding DN, Nichol G, Thomas WD, Jr, Leney M, Sloan S, Hay CA, Ambrosino DM. 2010. Treatment with monoclonal antibodies against Clostridium difficile toxins. N. Engl. J. Med. 362:197-205. doi:10.1056/NEJMoa0907635.
-
(2010)
N. Engl. J. Med.
, vol.362
, pp. 197-205
-
-
Lowy, I.1
Molrine, D.C.2
Leav, B.A.3
Blair, B.M.4
Baxter, R.5
Gerding, D.N.6
Nichol, G.7
Thomas Jr., W.D.8
Leney, M.9
Sloan, S.10
Hay, C.A.11
Ambrosino, D.M.12
-
27
-
-
59349085748
-
Toxin-binding treatment for Clostridium difficile: A review including reports of studies with tolevamer
-
Weiss K. 2009. Toxin-binding treatment for Clostridium difficile: A review including reports of studies with tolevamer. Int. J. Antimicrob. Agents 33:4-7.
-
(2009)
Int. J. Antimicrob. Agents
, vol.33
, pp. 4-7
-
-
Weiss, K.1
-
28
-
-
0030807266
-
Effect of vancomycin on intestinal flora of patients who previously received antimicrobial therapy
-
Edlund C, Barkholt L, Olsson-Liljequist B, Nord CE. 1997. Effect of vancomycin on intestinal flora of patients who previously received antimicrobial therapy. Clin. Infect. Dis. 25:729-732.
-
(1997)
Clin. Infect. Dis.
, vol.25
, pp. 729-732
-
-
Edlund, C.1
Barkholt, L.2
Olsson-Liljequist, B.3
Nord, C.E.4
-
29
-
-
59749103290
-
OPT-80 eliminates Clostridium difficile and is sparing of Bacteroides species during treatment of C. difficile infection
-
doi:10.1128/AAC.01443-07
-
Louie TJ, Emery J, Krulicki W, Byrne B, Mah M. 2009. OPT-80 eliminates Clostridium difficile and is sparing of Bacteroides species during treatment of C. difficile infection. Antimicrob. Agents Chemother. 53: 261-263. doi:10.1128/AAC.01443-07.
-
(2009)
Antimicrob. Agents Chemother.
, vol.53
, pp. 261-263
-
-
Louie, T.J.1
Emery, J.2
Krulicki, W.3
Byrne, B.4
Mah, M.5
-
30
-
-
78049517194
-
A new macrocyclic antibiotic, fidaxomicin (OPT-80), causes less alteration to the bowel microbiota of Clostridium difficileinfected patients than does vancomycin
-
doi:10.1099/mic.0.042010-0
-
Tannock GW, Munro K, Taylor C, Lawley B, Young W, Byrne B, Emery J, Louie T. 2010. A new macrocyclic antibiotic, fidaxomicin (OPT-80), causes less alteration to the bowel microbiota of Clostridium difficileinfected patients than does vancomycin. Microbiology 156:3354-3359. doi:10.1099/mic.0.042010-0.
-
(2010)
Microbiology
, vol.156
, pp. 3354-3359
-
-
Tannock, G.W.1
Munro, K.2
Taylor, C.3
Lawley, B.4
Young, W.5
Byrne, B.6
Emery, J.7
Louie, T.8
|