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Volumn 73, Issue 3, 2013, Pages 316-327

Prostate epithelial AR inactivation leads to increased intraprostatic androgen synthesis

Author keywords

5 R2; androgen independence; AR; PEARKO mice; prostate

Indexed keywords

ANDROGEN RECEPTOR; ESTRADIOL; TESTOSTERONE;

EID: 84872815304     PISSN: 02704137     EISSN: 10970045     Source Type: Journal    
DOI: 10.1002/pros.22570     Document Type: Article
Times cited : (7)

References (54)
  • 1
    • 42149122668 scopus 로고    scopus 로고
    • The worldwide epidemiology of prostate cancer: Perspectives from autopsy studies
    • Haas GP, Delongchamps N, Brawley OW, Wang CY, de la Roza G,. The worldwide epidemiology of prostate cancer: Perspectives from autopsy studies. Can J Urol 2008; 15 (1): 3866-3871.
    • (2008) Can J Urol , vol.15 , Issue.1 , pp. 3866-3871
    • Haas, G.P.1    Delongchamps, N.2    Brawley, O.W.3    Wang, C.Y.4    De La Roza, G.5
  • 2
    • 34447529184 scopus 로고    scopus 로고
    • Commentary: Prostate cancer is omnipresent, but should we screen for it
    • Martin RM,. Commentary: Prostate cancer is omnipresent, but should we screen for it ? Int J Epidemiol 2007; 36 (2): 278-281.
    • (2007) Int J Epidemiol , vol.36 , Issue.2 , pp. 278-281
    • Martin, R.M.1
  • 4
    • 0029910571 scopus 로고    scopus 로고
    • Differential expression of 5 alpha-reductase isoenzymes in the human prostate and prostatic carcinomas
    • Bonkhoff H, Stein U, Aumuller G, Remberger K,. Differential expression of 5 alpha-reductase isoenzymes in the human prostate and prostatic carcinomas. Prostate 1996; 29 (4): 261-267.
    • (1996) Prostate , vol.29 , Issue.4 , pp. 261-267
    • Bonkhoff, H.1    Stein, U.2    Aumuller, G.3    Remberger, K.4
  • 5
    • 42949156786 scopus 로고    scopus 로고
    • Intra-prostatic androgen levels during various androgen-blockade regimens
    • Nishiyama T,. Intra-prostatic androgen levels during various androgen-blockade regimens. Best Pract Res Clin Endocrinol Metab 2008; 22 (2): 229-241.
    • (2008) Best Pract Res Clin Endocrinol Metab , vol.22 , Issue.2 , pp. 229-241
    • Nishiyama, T.1
  • 6
    • 42949144171 scopus 로고    scopus 로고
    • Intracrine androgen metabolism in prostate cancer progression: Mechanisms of castration resistance and therapeutic implications
    • Mostaghel EA, Nelson PS,. Intracrine androgen metabolism in prostate cancer progression: Mechanisms of castration resistance and therapeutic implications. Best Pract Res Clin Endocrinol Metab 2008; 22 (2): 243-258.
    • (2008) Best Pract Res Clin Endocrinol Metab , vol.22 , Issue.2 , pp. 243-258
    • Mostaghel, E.A.1    Nelson, P.S.2
  • 7
    • 5444272803 scopus 로고    scopus 로고
    • Cellular localization of mRNA expression of enzymes involved in the formation and inactivation of hormonal steroids in the mouse prostate
    • Pelletier G, Luu-The V, Li S, Ouellet J, Labrie F,. Cellular localization of mRNA expression of enzymes involved in the formation and inactivation of hormonal steroids in the mouse prostate. J Histochem Cytochem 2004; 52 (10): 1351-1356.
    • (2004) J Histochem Cytochem , vol.52 , Issue.10 , pp. 1351-1356
    • Pelletier, G.1    Luu-The, V.2    Li, S.3    Ouellet, J.4    Labrie, F.5
  • 8
    • 34548814957 scopus 로고    scopus 로고
    • 5alpha-reductase: History and clinical importance
    • Marks LS,. 5alpha-reductase: History and clinical importance. Rev Urol 2004; 6 (Suppl 9): S11-S21.
    • (2004) Rev Urol , vol.6 , Issue.SUPPL. 9
    • Marks, L.S.1
  • 9
    • 36949000088 scopus 로고    scopus 로고
    • Novel 5 alpha-steroid reductase (SRD5A3, type-3) is overexpressed in hormone-refractory prostate cancer
    • Uemura M, Tamura K, Chung S, Honma S, Okuyama A, Nakamura Y, Nakagawa H,. Novel 5 alpha-steroid reductase (SRD5A3, type-3) is overexpressed in hormone-refractory prostate cancer. Cancer Sci 2008; 99 (1): 81-86.
    • (2008) Cancer Sci , vol.99 , Issue.1 , pp. 81-86
    • Uemura, M.1    Tamura, K.2    Chung, S.3    Honma, S.4    Okuyama, A.5    Nakamura, Y.6    Nakagawa, H.7
  • 10
    • 0030026298 scopus 로고    scopus 로고
    • Immunohistochemical localization of steroid 5 alpha-reductase 2 in the human male fetal reproductive tract and adult prostate
    • Levine AC, Wang JP, Ren M, Eliashvili E, Russell DW, Kirschenbaum A,. Immunohistochemical localization of steroid 5 alpha-reductase 2 in the human male fetal reproductive tract and adult prostate. J Clin Endocrinol Metab 1996; 81 (1): 384-389.
    • (1996) J Clin Endocrinol Metab , vol.81 , Issue.1 , pp. 384-389
    • Levine, A.C.1    Wang, J.P.2    Ren, M.3    Eliashvili, E.4    Russell, D.W.5    Kirschenbaum, A.6
  • 11
    • 39149084101 scopus 로고    scopus 로고
    • Endogenous sex hormones and prostate cancer: A collaborative analysis of 18 prospective studies
    • Roddam AW, Allen NE, Appleby P, Key TJ,. Endogenous sex hormones and prostate cancer: A collaborative analysis of 18 prospective studies. J Natl Cancer Inst 2008; 100 (3): 170-183.
    • (2008) J Natl Cancer Inst , vol.100 , Issue.3 , pp. 170-183
    • Roddam, A.W.1    Allen, N.E.2    Appleby, P.3    Key, T.J.4
  • 12
    • 0034743536 scopus 로고    scopus 로고
    • Steroid 5 alpha-reductases and 3 alpha hydroxysteroid dehydrogenases: Key enzymes in androgen metabolism
    • Jin Y, Penning TM,. Steroid 5 alpha-reductases and 3 alpha hydroxysteroid dehydrogenases: Key enzymes in androgen metabolism. Best Pract Res Clin Endocrinol Metabol 2001; 15 (1): 79-94.
    • (2001) Best Pract Res Clin Endocrinol Metabol , vol.15 , Issue.1 , pp. 79-94
    • Jin, Y.1    Penning, T.M.2
  • 13
    • 0031714004 scopus 로고    scopus 로고
    • Expression of androgen receptor and growth factors in premalignant lesions of the prostate
    • Harper ME, Glynne-Jones E, Goddard L, Mathews P, Nicholson RI,. Expression of androgen receptor and growth factors in premalignant lesions of the prostate. J Pathol 1998; 186 (2): 169-177.
    • (1998) J Pathol , vol.186 , Issue.2 , pp. 169-177
    • Harper, M.E.1    Glynne-Jones, E.2    Goddard, L.3    Mathews, P.4    Nicholson, R.I.5
  • 14
    • 42249106022 scopus 로고    scopus 로고
    • Co-assessment of cytoplasmic and nuclear androgen receptor location in prostate specimens: Potential implications for prostate cancer development and prognosis
    • Diallo JS, Aldejmah A, Mouhim AF, Fahmy MA, Koumakpayi IH, Sircar K, Begin LR, Mes-Masson AM, Saad F,. Co-assessment of cytoplasmic and nuclear androgen receptor location in prostate specimens: Potential implications for prostate cancer development and prognosis. BJU Int 2008; 101 (10): 1302-1309.
    • (2008) BJU Int , vol.101 , Issue.10 , pp. 1302-1309
    • Diallo, J.S.1    Aldejmah, A.2    Mouhim, A.F.3    Fahmy, M.A.4    Koumakpayi, I.H.5    Sircar, K.6    Begin, L.R.7    Mes-Masson, A.M.8    Saad, F.9
  • 15
    • 0035361340 scopus 로고    scopus 로고
    • A mechanism for androgen receptor-mediated prostate cancer recurrence after androgen deprivation therapy
    • Gregory CW, He B, Johnson RT, Ford OH, Mohler JL, French FS, Wilson EM,. A mechanism for androgen receptor-mediated prostate cancer recurrence after androgen deprivation therapy. Cancer Res 2001; 61 (11): 4315-4319.
    • (2001) Cancer Res , vol.61 , Issue.11 , pp. 4315-4319
    • Gregory, C.W.1    He, B.2    Johnson, R.T.3    Ford, O.H.4    Mohler, J.L.5    French, F.S.6    Wilson, E.M.7
  • 16
    • 37349107226 scopus 로고    scopus 로고
    • Type 1 and type 2 5alpha-reductase expression in the development and progression of prostate cancer
    • Thomas LN, Douglas RC, Lazier CB, Too CK, Rittmaster RS, Tindall DJ,. Type 1 and type 2 5alpha-reductase expression in the development and progression of prostate cancer. Eur Urol 2008; 53 (2): 244-252.
    • (2008) Eur Urol , vol.53 , Issue.2 , pp. 244-252
    • Thomas, L.N.1    Douglas, R.C.2    Lazier, C.B.3    Too, C.K.4    Rittmaster, R.S.5    Tindall, D.J.6
  • 18
    • 79951838692 scopus 로고    scopus 로고
    • Activation of the androgen receptor by intratumoral bioconversion of androstanediol to dihydrotestosterone in prostate cancer
    • Mohler JL, Titus MA, Bai S, Kennerley BJ, Lih FB, Tomer KB, Wilson EM,. Activation of the androgen receptor by intratumoral bioconversion of androstanediol to dihydrotestosterone in prostate cancer. Cancer Res 2011; 71 (4): 1486-1496.
    • (2011) Cancer Res , vol.71 , Issue.4 , pp. 1486-1496
    • Mohler, J.L.1    Titus, M.A.2    Bai, S.3    Kennerley, B.J.4    Lih, F.B.5    Tomer, K.B.6    Wilson, E.M.7
  • 20
    • 0025873322 scopus 로고
    • Feed-forward control of prostate growth: Dihydrotestosterone induces expression of its own biosynthetic enzyme, steroid 5 alpha-reductase
    • George FW, Russell DW, Wilson JD,. Feed-forward control of prostate growth: dihydrotestosterone induces expression of its own biosynthetic enzyme, steroid 5 alpha-reductase. Proc Natl Acad Sci USA 1991; 88 (18): 8044-8047.
    • (1991) Proc Natl Acad Sci USA , vol.88 , Issue.18 , pp. 8044-8047
    • George, F.W.1    Russell, D.W.2    Wilson, J.D.3
  • 21
    • 0026723090 scopus 로고
    • Tissue distribution and kinetic characteristics of rat steroid 5 alpha-reductase isozymes. Evidence for distinct physiological functions
    • Normington K, Russell DW,. Tissue distribution and kinetic characteristics of rat steroid 5 alpha-reductase isozymes. Evidence for distinct physiological functions. J Biol Chem 1992; 267 (27): 19548-19554.
    • (1992) J Biol Chem , vol.267 , Issue.27 , pp. 19548-19554
    • Normington, K.1    Russell, D.W.2
  • 22
    • 3843075116 scopus 로고    scopus 로고
    • Localization of estrogen and androgen receptors in male reproductive tissues of mice and rats
    • Yamashita S,. Localization of estrogen and androgen receptors in male reproductive tissues of mice and rats. Anat Rec A Discov Mol Cell Evol Biol 2004; 279 (2): 768-778.
    • (2004) Anat Rec A Discov Mol Cell Evol Biol , vol.279 , Issue.2 , pp. 768-778
    • Yamashita, S.1
  • 24
    • 66849128249 scopus 로고    scopus 로고
    • Androgen sensitivity of prostate epithelium is enhanced by postnatal androgen receptor inactivation
    • Simanainen U, McNamara K, Gao YR, Handelsman DJ,. Androgen sensitivity of prostate epithelium is enhanced by postnatal androgen receptor inactivation. Am J Physiol Endocrinol Metab 2009; 296 (6): E1335-E1343.
    • (2009) Am J Physiol Endocrinol Metab , vol.296 , Issue.6
    • Simanainen, U.1    McNamara, K.2    Gao, Y.R.3    Handelsman, D.J.4
  • 29
    • 12144290810 scopus 로고    scopus 로고
    • Prostate pathology of genetically engineered mice: Definitions and classification. The consensus report from the Bar Harbor meeting of the Mouse Models of Human Cancer Consortium Prostate Pathology Committee
    • Shappell SB, Thomas GV, Roberts RL, Herbert R, Ittmann MM, Rubin MA, Humphrey PA, Sundberg JP, Rozengurt N, Barrios R, Ward JM, Cardiff RD,. Prostate pathology of genetically engineered mice: Definitions and classification. The consensus report from the Bar Harbor meeting of the Mouse Models of Human Cancer Consortium Prostate Pathology Committee. Cancer Res 2004; 64 (6): 2270-2305.
    • (2004) Cancer Res , vol.64 , Issue.6 , pp. 2270-2305
    • Shappell, S.B.1    Thomas, G.V.2    Roberts, R.L.3    Herbert, R.4    Ittmann, M.M.5    Rubin, M.A.6    Humphrey, P.A.7    Sundberg, J.P.8    Rozengurt, N.9    Barrios, R.10    Ward, J.M.11    Cardiff, R.D.12
  • 30
    • 78751580474 scopus 로고    scopus 로고
    • Increased 5alpha-reductase type 2 expression in human breast carcinoma following aromatase inhibitor therapy: The correlation with decreased tumor cell proliferation
    • Chanplakorn N, Chanplakorn P, Suzuki T, Ono K, Wang L, Chan MS, Wing L, Yiu CC, Chow LW, Sasano H,. Increased 5alpha-reductase type 2 expression in human breast carcinoma following aromatase inhibitor therapy: The correlation with decreased tumor cell proliferation. Horm Cancer 2011; 2 (1): 73-81.
    • (2011) Horm Cancer , vol.2 , Issue.1 , pp. 73-81
    • Chanplakorn, N.1    Chanplakorn, P.2    Suzuki, T.3    Ono, K.4    Wang, L.5    Chan, M.S.6    Wing, L.7    Yiu, C.C.8    Chow, L.W.9    Sasano, H.10
  • 32
    • 77954856291 scopus 로고    scopus 로고
    • Measurement of sex steroids in murine blood and reproductive tissues by liquid chromatography tandem mass spectrometry
    • McNamara KM, Harwood DT, Simanainen U, Walters KA, Jimenez M, Handelsman DJ,. Measurement of sex steroids in murine blood and reproductive tissues by liquid chromatography tandem mass spectrometry. J Steroid Biochem Mol Biol 2010; 121 (3-5): 611-618.
    • (2010) J Steroid Biochem Mol Biol , vol.121 , Issue.35 , pp. 611-618
    • McNamara, K.M.1    Harwood, D.T.2    Simanainen, U.3    Walters, K.A.4    Jimenez, M.5    Handelsman, D.J.6
  • 33
    • 0032535307 scopus 로고    scopus 로고
    • Androgen receptor expression in androgen-independent prostate cancer is associated with increased expression of androgen-regulated genes
    • Gregory CW, Hamil KG, Kim D, Hall SH, Pretlow TG, Mohler JL, French FS,. Androgen receptor expression in androgen-independent prostate cancer is associated with increased expression of androgen-regulated genes. Cancer Res 1998; 58 (24): 5718-5724.
    • (1998) Cancer Res , vol.58 , Issue.24 , pp. 5718-5724
    • Gregory, C.W.1    Hamil, K.G.2    Kim, D.3    Hall, S.H.4    Pretlow, T.G.5    Mohler, J.L.6    French, F.S.7
  • 34
    • 0021868640 scopus 로고
    • Metabolism of androgens in the seminal vesicles and the different lobes of the prostate in young mature rats
    • Lundmo PI, Sunde A, Tveter KJ,. Metabolism of androgens in the seminal vesicles and the different lobes of the prostate in young mature rats. J Steroid Biochem 1985; 22 (4): 513-519.
    • (1985) J Steroid Biochem , vol.22 , Issue.4 , pp. 513-519
    • Lundmo, P.I.1    Sunde, A.2    Tveter, K.J.3
  • 35
    • 0037085732 scopus 로고    scopus 로고
    • Transcriptional regulation of the mouse steroid 5alpha-reductase type II gene by progesterone in brain
    • Matsui D, Sakari M, Sato T, Murayama A, Takada I, Kim M, Takeyama K, Kato S,. Transcriptional regulation of the mouse steroid 5alpha-reductase type II gene by progesterone in brain. Nucleic Acids Res 2002; 30 (6): 1387-1393.
    • (2002) Nucleic Acids Res , vol.30 , Issue.6 , pp. 1387-1393
    • Matsui, D.1    Sakari, M.2    Sato, T.3    Murayama, A.4    Takada, I.5    Kim, M.6    Takeyama, K.7    Kato, S.8
  • 36
    • 0019799945 scopus 로고
    • Stromal-epithelial interactions-I. Induction of prostatic phenotype in urothelium of testicular feminized (Tfm/y) mice
    • Cunha GR, Chung LW,. Stromal-epithelial interactions-I. Induction of prostatic phenotype in urothelium of testicular feminized (Tfm/y) mice. J Steroid Biochem 1981; 14 (12): 1317-1324.
    • (1981) J Steroid Biochem , vol.14 , Issue.12 , pp. 1317-1324
    • Cunha, G.R.1    Chung, L.W.2
  • 37
    • 0035862917 scopus 로고    scopus 로고
    • Evidence that epithelial and mesenchymal estrogen receptor-alpha mediates effects of estrogen on prostatic epithelium
    • Risbridger G, Wang H, Young P, Kurita T, Wang YZ, Lubahn D, Gustafsson JA, Cunha G,. Evidence that epithelial and mesenchymal estrogen receptor-alpha mediates effects of estrogen on prostatic epithelium. Dev Biol 2001; 229 (2): 432-442.
    • (2001) Dev Biol , vol.229 , Issue.2 , pp. 432-442
    • Risbridger, G.1    Wang, H.2    Young, P.3    Kurita, T.4    Wang, Y.Z.5    Lubahn, D.6    Gustafsson, J.A.7    Cunha, G.8
  • 38
    • 79951527527 scopus 로고    scopus 로고
    • Altered prostate epithelial development and IGF-1 signal in mice lacking the androgen receptor in stromal smooth muscle cells
    • Yu S, Zhang C, Lin CC, Niu Y, Lai KP, Chang HC, Yeh SD, Chang C, Yeh S,. Altered prostate epithelial development and IGF-1 signal in mice lacking the androgen receptor in stromal smooth muscle cells. Prostate 2011; 71 (5): 517-524.
    • (2011) Prostate , vol.71 , Issue.5 , pp. 517-524
    • Yu, S.1    Zhang, C.2    Lin, C.C.3    Niu, Y.4    Lai, K.P.5    Chang, H.C.6    Yeh, S.D.7    Chang, C.8    Yeh, S.9
  • 41
    • 84856026139 scopus 로고    scopus 로고
    • Altered prostate epithelial development in mice lacking the androgen receptor in stromal fibroblasts
    • Yu S, Yeh CR, Niu Y, Chang HC, Tsai YC, Moses HL, Shyr CR, Chang C, Yeh S,. Altered prostate epithelial development in mice lacking the androgen receptor in stromal fibroblasts. Prostate 2012; 72 (4): 437-439.
    • (2012) Prostate , vol.72 , Issue.4 , pp. 437-439
    • Yu, S.1    Yeh, C.R.2    Niu, Y.3    Chang, H.C.4    Tsai, Y.C.5    Moses, H.L.6    Shyr, C.R.7    Chang, C.8    Yeh, S.9
  • 42
    • 0032525021 scopus 로고    scopus 로고
    • Sex hormone-induced prostatic carcinogenesis in the noble rat: The role of insulin-like growth factor-I (IGF-I) and vascular endothelial growth factor (VEGF) in the development of prostate cancer
    • Wang YZ, Wong YC,. Sex hormone-induced prostatic carcinogenesis in the noble rat: The role of insulin-like growth factor-I (IGF-I) and vascular endothelial growth factor (VEGF) in the development of prostate cancer. Prostate 1998; 35 (3): 165-177.
    • (1998) Prostate , vol.35 , Issue.3 , pp. 165-177
    • Wang, Y.Z.1    Wong, Y.C.2
  • 43
    • 22444445853 scopus 로고    scopus 로고
    • Steroids and the scientist
    • Gustafsson JA,. Steroids and the scientist. Mol Endocrinol 2005; 19 (6): 1412-1417.
    • (2005) Mol Endocrinol , vol.19 , Issue.6 , pp. 1412-1417
    • Gustafsson, J.A.1
  • 44
    • 0037109138 scopus 로고    scopus 로고
    • An endocrine pathway in the prostate, ERbeta, AR, 5alpha-androstane- 3beta, 17beta-diol, and CYP7B1, regulates prostate growth
    • Weihua Z, Lathe R, Warner M, Gustafsson JA,. An endocrine pathway in the prostate, ERbeta, AR, 5alpha-androstane-3beta, 17beta-diol, and CYP7B1, regulates prostate growth. Proc Natl Acad Sci USA 2002; 99 (21): 13589-13594.
    • (2002) Proc Natl Acad Sci USA , vol.99 , Issue.21 , pp. 13589-13594
    • Weihua, Z.1    Lathe, R.2    Warner, M.3    Gustafsson, J.A.4
  • 46
    • 3042586045 scopus 로고    scopus 로고
    • Estrogen receptor beta regulates epithelial cellular differentiation in the mouse ventral prostate
    • Imamov O, Morani A, Shim G-J, Omoto Y, Thulin-Andersson C, Warner M, Gustafsson JA,. Estrogen receptor beta regulates epithelial cellular differentiation in the mouse ventral prostate. PNAS 2004; 101 (25): 9375-9380.
    • (2004) PNAS , vol.101 , Issue.25 , pp. 9375-9380
    • Imamov, O.1    Morani, A.2    Shim, G.-J.3    Omoto, Y.4    Thulin-Andersson, C.5    Warner, M.6    Gustafsson, J.A.7
  • 48
    • 50249118153 scopus 로고    scopus 로고
    • 5alpha-androstane-3alpha,17beta-diol supports human prostate cancer cell survival and proliferation through androgen receptor-independent signaling pathways: Implication of androgen-independent prostate cancer progression
    • Yang Q, Titus MA, Fung KM, Lin HK,. 5alpha-androstane-3alpha,17beta-diol supports human prostate cancer cell survival and proliferation through androgen receptor-independent signaling pathways: Implication of androgen-independent prostate cancer progression. J Cell Biochem 2008; 104 (5): 1612-1624.
    • (2008) J Cell Biochem , vol.104 , Issue.5 , pp. 1612-1624
    • Yang, Q.1    Titus, M.A.2    Fung, K.M.3    Lin, H.K.4
  • 49
    • 0018909420 scopus 로고
    • Alteration in the metabolism of dihydrotestosterone in elderly men with prostate hyperplasia
    • Morimoto I, Edmiston A, Horton R,. Alteration in the metabolism of dihydrotestosterone in elderly men with prostate hyperplasia. J Clin Invest 1980; 66 (3): 612-615.
    • (1980) J Clin Invest , vol.66 , Issue.3 , pp. 612-615
    • Morimoto, I.1    Edmiston, A.2    Horton, R.3
  • 50
    • 0028173882 scopus 로고
    • Steroid 5 alpha-reductase: Two genes/two enzymes
    • Russell DW, Wilson JD,. Steroid 5 alpha-reductase: Two genes/two enzymes. Annu Rev Biochem 1994; 63: 25-61.
    • (1994) Annu Rev Biochem , vol.63 , pp. 25-61
    • Russell, D.W.1    Wilson, J.D.2
  • 51
    • 84862861767 scopus 로고    scopus 로고
    • The mouse as a model to investigate sex steroid metabolism in the normal and pathological prostate
    • McNamara KM, Handelsman DJ, Simanainen U,. The mouse as a model to investigate sex steroid metabolism in the normal and pathological prostate. J Steroid Biochem Mol Biol 2012; 131 (3-5): 107-121.
    • (2012) J Steroid Biochem Mol Biol , vol.131 , Issue.35 , pp. 107-121
    • McNamara, K.M.1    Handelsman, D.J.2    Simanainen, U.3
  • 53
    • 42949150940 scopus 로고    scopus 로고
    • Expression of steroidogenic enzymes and sex-steroid receptors in human prostate
    • Pelletier G,. Expression of steroidogenic enzymes and sex-steroid receptors in human prostate. Best Pract Res Clin Endocrinol Metab 2008; 22 (2): 223-228.
    • (2008) Best Pract Res Clin Endocrinol Metab , vol.22 , Issue.2 , pp. 223-228
    • Pelletier, G.1


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