Ozone oxidation of antidepressants in wastewater -Treatment evaluation and characterization of new by-products by LC-QToFMS

Chemistry Central Journal

Volumn 7, Issue 1, 2013, Pages

  Lajeunesse, André ^a   Blais, Mireille ^b   Barbeau, Benoît ^b   Sauvé, Sébastien ^c   Gagnon, Christian ^a  

^a ENVIRONMENT CANADA   (Canada)

^b ÉCOLE POLYTECHNIQUE DE MONTRÉAL   (Canada)

^c UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

Antidepressants; Biosolids; LC MS MS; Ozone; Sewage treatment plants; Side products

Indexed keywords

EID: 84872814968     PISSN: None     EISSN: 1752153X     Source Type: Journal    
DOI: 10.1186/1752-153X-7-15     Document Type: Article

References (40)

1. Halling-Sørensen B, Nors Nielsen S, Lanzky PF, Ingerslev F, Holten Lützhøft HC, Jørgensen SE. Occurence, fate and effect of pharmaceutical substances in the environment - A review. Chemosphere 1998, 36:357-393.
2. Daughton EG, Ternes TA. Pharmaceuticals and personal care products in the environment: agents of subtle change?. Environ Health Perspect 1999, 107:907-938.
3. Heberer T. Occurence, fate and removal of pharmaceuticals residues in the aquatic environment: A review of recent research data. Toxicol Lett 2002, 131(1-2):5-17.
4. Ternes TA. Occurrence of drugs in German sewage plants and rivers. Water Res 1998, 32:3245-3260.
5. Oulton RL, Kohn T, Cwiertny DM. Pharmaceuticals and personal care products in effluent matrices: a survey of transformation and removal during wastewater treatment and implications for wastewater management. J Environ Monit 2010, 12:1956-1978.
6. Vasskog T, Anderssen T, Pedersen-Bjergaard S, Kallenborn R, Jensen E. Occurrence of selective serotonin reuptake inhibitors in sewage and receiving waters at Spitsbergen and in Norway. J Chromatogr A 2008, 1185:194-205.
7. Van Rooyen GF, Badenhorst D, Swart KJ, Hundt HKL, Scanes T, Hundt AF. Determination of carbamazepine and carbamazepine 10,11-epoxide in human plasma by tandem liquid chromatography-mass spectrometry with electrospray ionisation. J Chromatogr B 2002, 769:1-7.
8. Calisto V, Esteves VI. Psychiatric pharmaceuticals in the environment. Chemosphere 2009, 77:1257-1274.
9. Fong PP. Antidepressants in aquatic organisms: a wide range of effects. Pharmaceuticals and Personal Care Products in the environment 2001, 264-281. Washington, USA: Scientific and regulatory issue, ACS Symposium series, Daughton CG, Jones-Lepp TL.
10. Gagné F, Blaise C, Fournier M, Hansen PD. Effects of selected pharmaceutical products on phagocytic activity in Elliptio complanata mussels. Comp Biochem Physiol 2006, C143:179-186.
11. Mennigen JA, Lado WE, Zamora JM, Duarte-Guterman P, Langlois VS, Metcalfe CD, Chang JP, Moon TW, Trudeau VL. Waterborne fluoxetine disrupts the reproductive axis in sexually mature male goldfish, Carassius auratus. Aquat Toxicol 2010, 100:354-364.
12. Lajeunesse A, Gagnon C, Gagné F, Louis S, Čejka P, Sauvé S. Distribution of antidepressants and their metabolites in brook trout exposed to municipal wastewaters before and after ozone treatment - Evidence of biological effects. Chemosphere 2011, 83:564-571.
13. Lazzara R, Blázquez M, Porte C, Barata C. Low environmental levels of fluoxetine induce spawning and changes in endogenous estradiol levels in the zebra mussel Dreissena polymorpha. Aquat Toxicol 2012, 106-107:123-130.
14. Rúa-Gómez P, Püttmann W. Impact of wastewater treatment plant discharge of lidocaine, tramadol, venlafaxine and their metabolites on the quality of surface waters and groundwater. J Environ Monit 2012, 14:1391-1399.
15. Lajeunesse A, Gagnon C, Sauvé S. Determination of basic antidepressants and their N-desmethyl metabolites in raw sewage and wastewater using solid-phase extraction and liquid chromatography-tandem mass spectrometry. Anal Chem 2008, 80:5325-5333.
16. Schultz MM, Furlong ET. Trace analysis of antidepressants pharmaceuticals and their select degradates in aquatic matrixes by LC/ESI/MS/MS. Anal Chem 2008, 80:1756-1762.
17. Metcalfe CD, Chu S, Judt C, Li H, Oakes KD, Servos MR, Andrews DM. Antidepressants and their metabolites in municipal wastewater, and downstream exposure in an urban watershed. Environ Toxicol Chem 2010, 29:79-89.
18. Radjenović J, Jelić A, Petrović M, Barceló D. Determination of pharmaceuticals in sewage sludge by pressurized liquid extraction (PLE) coupled to liquid chromatography-tandem mass spectrometry. Anal Bioanal Chem 2009, 393:1685-1695.
19. Hörsing M, Ledin A, Grabic R, Fick J, Tysklind M, la Cour Jansen J, Andersen HR. Determination of sorption of seventy-five pharmaceuticals in sewage sludge. Water Res 2011, 45:4470-4482.
20. Lajeunesse A, Smyth SA, Barclay K, Sauvé S, Gagnon C. Distribution of antidepressant residues in wastewater and biosolids following different treatment processes by municipal wastewater treatment plants in Canada. Water Res 2012, 46:5600-5612.
21. Oller I, Malato S, Sánchez-Pérez JA. Combination of advanced oxidation Processes and biological treatments for wastewater decontamination - A review. Sci Tot Environ 2011, 409:4141-4166.
22. Benotti M, Stanford B, Wert E, Snyder S. Evaluation of a photocatalytic reactor membrane pilot system for the removal of pharmaceuticals and endocrine disrupting compounds from water. Water Res 2009, 43:1513-1522.
23. Wert E, Rosario-Ortiz F, Snyder S. Effect of ozone exposure on the oxidation of trace organic contaminants in wastewater. Water Res 2009, 43:1005-1014.
24. Méndez-Arriaga F, Otsu T, Oyama T, Gimenez J, Esplugas S, Hidaka H, Serpone N. Photooxidation of the antidepressant drug fluoxetine (Prozac®) in aqueous media by hybrid catalytic/ozonation processes. Water Res 2011, 45:2782-2794.
25. Huber MM, Göbel A, Joss A, Hermann N, Löffler D, Mcardell CS, Ried A, Siegrist H, Terne TA, von Gunten U. Oxidation of pharmaceuticals during ozonation of municipal wastewater effluent: A pilot study. Environ Sci Technol 2005, 39:4290-4299.
26. Snyder SA, Wert EC, Rexing DJ, Zegers RE, Drury DD. Ozone oxidation of endocrine disruptors and pharmaceuticals in surface water and wastewater. Ozone Sci Eng 2006, 28:455-460.
27. Gagnon C, Lajeunesse A, Cejka P, Gagné F, Hausler R. Degradation of selected acidic and neutral pharmaceutical products in a primary-treated wastewater by disinfection processes. Ozone Sci Eng 2008, 30:387-392.
28. Langlais B, Reckhow DA, Brink DR. Chapter II: Fundamental aspects. Ozone in water treatment - Application and engineering. AWWA Research Association / Compagnie Générale des eaux 1991, 11-79. Michigan, USA: Lewis publishers inc, Langlais B, Reckhow DA, Brink DR.
29. Tomiyasu H, Fukutomi H, Gordon G. Kinetics and mechanism of ozone decomposition in basic aqueous solution. Inorg Chem 1985, 24:2962-2966.
30. Dodd MC, Rentsch D, Singer HP, Kohler H-PE, von Gunten U. Transformation of β-Lactam antibacterial agents during aqueous ozonation: reaction pathways and quantitative bioassay of biologically-active oxidation products. Environ Sci Technol 2010, 44:5940-5948.
31. Elmghari-Tabib M, Laplanche A, Venien F, Martin G. Ozonation of amines in aqueous solutions. Water Res 1982, 16:223-229.
32. Elmghari-Tabib M, Dalouche A, Faujour C, Venien E, Martin G, Legeron JP. Ozonation reaction patterns of alcohols and aliphatic amines. Ozone Sci Eng 1982, 4:195-205.
33. Standard method 2350. Oxidant demand / Requirement 2007, Approved by SM Committee.
34. U.S. Environmental Protection Agency (EPA) Standard method 4500-03 B for ozone 2005, U.S: Environmental Protection Agency (EPA), 21, Standard methods for the examination of water and wastewater, U.S. Environmental Protection Agency (EPA).
35. Lajeunesse A, Gagnon C. Determination of acidic pharmaceutical products and carbamazepine in roughly primary-treated wastewater by solid-phase extraction and gas chromatography-tandem mass spectrometry. Intern J Environ Anal Chem 2007, 87:565-578.
36. Deegan AM, Shaik B, Nolan K, Urell K, Oelgemöller M, Tobin J, Morrisey A. Treatment options for wastewater effluents from pharmaceutical companies. Int J Environ Sci Tech 2011, 8:649-666.
37. Trimm DL. Chapter 4: The liquid phase oxidation of sulphur, nitrogen, and chlorine compounds. Comprehensive chemical kinetics - Vol. 16 Liquid phase oxidation 1980, 205-249. Amsterdam, The Netherlands: Elsevier Scientific Publishing Company, Bamford CH, Tipper CFH.
38. Zwiener C, Frimmel FH. Oxidative treatment of pharmaceuticals in water. Water Res 2000, 34(6):1881-1885.
39. Rosal R, Rodríguez A, Perdigón-Melón JA, Petre A, García-Calvo E, Gómez MJ, Agüera A, Fernández-Alba AR. Occurrence of emerging pollutants in urban wastewater and their removal through biological treatment followed by ozonation. Water Res 2010, 44:578-588.
40. Commission of the European Communities: Commission Decision (2002/657/EC) of 12 August 2002 Implementing Council Directive 96/23/EC concerning the performance of analytical methods and the interpretation of results. Off J Eur Commun 2002, (8):L221-17. Internet access: http://www.ecolex.org, Commission of the European Communities: Commission Decision (2002/657/EC) of 12 August 2002.