Distribution of antidepressant residues in wastewater and biosolids following different treatment processes by municipal wastewater treatment plants in Canada

Water Research

Volumn 46, Issue 17, 2012, Pages 5600-5612

  Lajeunesse, A ^a   Smyth, S A ^a   Barclay, K ^a   Sauve S ^b   Gagnon, C ^a  

^a ENVIRONMENT CANADA   (Canada)

^b UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

Antidepressants; LC MS MS; Pharmaceuticals; Sewage treatment plants; Treated biosolids; Wastewater

Indexed keywords

AMIDES; BIOLOGICAL SEWAGE TREATMENT; BIOMOLECULES; BIOSOLIDS; DRUG PRODUCTS; EFFLUENTS; FILTRATION; METABOLITES; PASSIVE FILTERS; SORPTION; WASTEWATER; WASTEWATER TREATMENT;

ANTIDEPRESSANTS; BIOLOGICAL AERATED FILTER; BIOLOGICAL NUTRIENT REMOVAL; DIFFERENT TREATMENTS; LC-MS/MS; MUNICIPAL WASTEWATER TREATMENT PLANTS; RECALCITRANT COMPOUNDS; SORPTION COEFFICIENTS;

SEWAGE TREATMENT PLANTS;

AMITRIPTYLINE; ANTIDEPRESSANT AGENT; CARBAMAZEPINE; CITALOPRAM; DESVENLAFAXINE; VENLAFAXINE;

BIOFILTRATION; BIOSOLID; CONCENTRATION (COMPOSITION); EFFLUENT; METABOLITE; SEWAGE TREATMENT; SORPTION; WASTEWATER;

ACTIVATED SLUDGE; ARTICLE; BIOLOGICAL AERATED FILTER; BIOSOLID; CANADA; FILTER; PRIORITY JOURNAL; SEWAGE TREATMENT PLANT; WASTE WATER MANAGEMENT; WASTE WATER TREATMENT PLANT;

CANADA;

EID: 84865969020     PISSN: 00431354     EISSN: 18792448     Source Type: Journal    
DOI: 10.1016/j.watres.2012.07.042     Document Type: Article

References (56)

1. Aboulfadl K., De Potter C., Prévost M., Sauvé S. Time-dependent integrity during storage of natural surface water samples for the trace analysis of pharmaceutical products, feminizing hormones and pesticides. Chemistry Central Journal 2010, 4:10.
2. Barron L., Tobin J., Paull B. Multi-residue determination of pharmaceuticals in sludge and sludge enriched soils using pressurized liquid extraction, solid phase extraction and liquid chromatography with tandem mass spectrometry. Journal of Environmental Monitoring 2008, 10:353-361.
3. Bergersen O., Hanssen K.Ø., Vasskog T. Anaerobic treatment of sewage sludge containing selective serotonin reuptake inhibitors. Bioresource Technology 2012, 117:325-332.
4. Calisto V., Esteves V.I. Psychiatric pharmaceuticals in the environment. Chemosphere 2009, 77:1257-1274.
5. Carballa M., Omil F., Ternes T., Lema J.M. Fate of pharmaceutical and personal care products (PPCPs) during anaerobic digestion of sewage sludge. Water Research 2007, 41:2139-2150.
6. Chenxi W., Spongberg A.L., Witter J.D. Determination of the persistence of pharmaceuticals in biosolids using liquid-chromatography tandem mass spectrometry. Chemosphere 2008, 73:511-518.
7. Chiou C.T., Peters L.J., Freed V.H. A physical concept of soil-water equilibria for non-ionic organic compounds. Science 1979, 206:831-832.
8. Daughton E.G., Ternes T.A. Pharmaceuticals and personal care products in the environment: agents of subtle change?. Environmental Health Perspectives 1999, 107:907-938.
9. Deegan A.M., Shaik B., Nolan K., Urell K., Oelgemöller M., Tobin J., Morrisey A. Treatment options for wastewater effluents from pharmaceutical companies. International Journal of Environmental Science and Technology 2011, 8:649-666.
10. Delle Site A. Factors affecting sorption of organic compounds in natural sorbent/water systems and sorption coefficients for selected pollutants: a review. Journal of Physical and Chemical Reference Data 2001, 30:213-216.
11. DeVane C.L. Metabolism and pharmacokinetics of selective serotonin reuptake inhibitors. Cellular and Molecular Neurobiology 1999, 19:443-465.
12. Englert B. Method 1694: Pharmaceuticals and Personal Care Products in Water, Soil, Sediment, and Biosolids by HPLC/MS/MS 2007, U.S. Environmental Protection Agency (EPA), EPA-821-R-08-002, 1-72.
13. Fong P.P. Chapter 15: antidepressants in aquatic organisms: a wide range of effects. ACS Symposium Series 2001, vol. 791. (Washington, USA). C.G. Daughton, T.L. Jones-Lepp (Eds.).
14. Göbel A., Thomsen A., McArdell C.S., Alder A.C., Giger W., Theiß N., Löffler D., Ternes T.A. Extraction and determination of sulfonamides, macrolides, and trimethoprim in sewage sludge. Journal of Chromatography A 2005, 1085:179-189.
15. Gómez M.J., Petrović M., Fernández-Alba A.R., Barceló D. Determination of pharmaceuticals of various therapeutic classes by solid-phase extraction and liquid chromatography-tandem mass spectrometry analysis in hospital effluent wastewaters. Journal of Chromatography A 2006, 1114:224-233.
16. Halling-Sørensen B., Nors Nielsen S., Lanzky P.F., Ingerslev F., Holten Lützhøft H.C., Jørgensen S.E. Occurrence, fate and effect of pharmaceutical substances in the environment - a review. Chemosphere 1998, 36(2):357-393.
17. Hayashi Y., Matsuda R., Ito K., Nishimura W., Imali K., Maeda M. Detection limit estimated from slope of calibration curve: an application to competitive ELISA. Analytical Science 2005, 21:167-169.
18. Heberer T. Occurrence, fate and removal of pharmaceuticals residues in the aquatic environment: a review of recent research data. Toxicology Letters 2002, 131:5-17.
19. Himmelsbach M., Buchberger W., Klampfl C.W. Determination of antidepressants in surface and waste water samples by capillary electrophoresis with electrospray ionization mass spectrometric detection after preconcentration using off-line solid-phase extraction. Electrophoresis 2006, 27:1220-1226.
20. Hörsing M., Ledin A., Grabic R., Fick J., Tysklind M., La Cour Jansen J., Andersen H.R. Determination of sorption of seventy-five pharmaceuticals in sewage sludge. Water Research 2011, 45:4470-4482.
21. Huq S., Dixon A., Teuscher J., Lok S., Kallury K. Application Note TN-008: Efficient Extraction of Basic Drugs from Biological Matrices Using a Polymeric Cationic Mixed-mode Sorbent Strata™X-C 2003, Phenomenex Inc., Torrance, CA, USA.
22. Jelić A., Petrović M., Barceló D. Multi-residue method for trace level determination of pharmaceuticals in solid samples using pressurized liquid extraction followed by liquid chromatography/quadrupole-linear ion trap mass spectrometry. Talanta 2009, 80:363-371.
23. Jones O.A., Voulvoulis N., Lester J.N. Partitioning behavior of five pharmaceuticals compounds to activated sludge and river sediment. Archives of Environmental Contamination and Toxicology 2006, 50:297-305.
24. Jones-Lepp T.L., Stevens R. Pharmaceuticals and personal care products in biosolids/sewage sludge: the interface between analytical chemistry and regulation. Analytical and Bioanalytical Chemistry 2007, 387:1173-1183.
25. Kinney C.A., Furlong E.T., Zaugg S.D., Burkhardt M.R., Werner S.L., Cahill J.D., Jorgensen G.R. Survey of organic wastewater contaminants in biosolids destined for land application. Environmental Science & Technology 2006, 40:7207-7215.
26. Koe B.K., Weissman A., Welch W.M., Browne R.G. Sertraline, 1S,4S-N-methyl-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthylamine, a new uptake inhibitor with selectivity for serotonin. Journal of Pharmacology and Experimental Therapeutics 1983, 226:686-700.
27. Kolpin D.W., Furlong E.T., Meyer M.T., Thurman E.M., Zaugg S.D., Barber L.B., Buxton H.T. Pharmaceuticals, hormones, and other organic wastewater contaminants in US streams, 1999-2000: a national reconnaissance. Environmental Science & Technology 2002, 36(6):1202-1211.
28. Lajeunesse A., Gagnon C., Sauvé S. Determination of basic antidepressants and their N-desmethyl metabolites in raw sewage and wastewater using solid-phase extraction and liquid chromatography-tandem mass spectrometry. Analytical Chemistry 2008, 80:5325-5333.
29. Lajeunesse A., Gagnon C., Gagné F., Louis S., čejka P., Sauvé S. Distribution of antidepressants and their metabolites in brook trout exposed to municipal wastewaters before and after ozone treatment - evidence of biological effects. Chemosphere 2011, 83:564-571.
30. Lamas J.P., Salgado-Petinal C., García-Jares C., Llompart M., Cela R., Gómez M. Solid-phase microextraction-gas chromatography-mass spectrometry for the analysis of selective serotonin reuptake inhibitors in environmental water. Journal of Chromatography A 2004, 1046:241-247.
31. Lazzara R., Blázquez M., Porte C., Barata C. Low environmental levels of fluoxetine induce spawning and changes in endogenous estradiol levels in the zebra mussel Dreissena polymorpha. Aquatic Toxicology 2012, 106-107:123-130.
32. Lishman L., Smyth S.A., Sarafin K., Kleywegt S., Toito J., Peart T., Lee B., Servos M., Beland M., Seto P. Occurrence and reductions of pharmaceuticals and personal care products and estrogens by municipal wastewater treatment plants in Ontario, Canada. Science of The Total Environment 2006, 367:544-558.
33. MacLeod S.L., Sudhir P., Wong C.S. Stereoisomer analysis of wastewater-derived β-blockers, selective serotonin re-uptake inhibitors, and salbutamol by high-performance liquid chromatography-tandem mass spectrometry. Journal of Chromatography A 2007, 1170:23-33.
34. Mennigen J.A., Lado W.E., Zamora J.M., Duarte-Guterman P., Langlois V.S., Metcalfe C.D., Chang J.P., Moon T.W., Trudeau V.L. Waterborne fluoxetine disrupts the reproductive axis in sexually mature male goldfish, Carassius auratus. Aquatic Toxicology 2010, 100:354-364.
35. Metcalfe C.D., Chu S., Judt C., Li H., Oakes K.D., Servos M.R., Andrews D.M. Antidepressants and their metabolites in municipal wastewater, and downstream exposure in an urban watershed. Environmental Toxicology & Chemistry 2010, 29:79-89.
36. Nieto A., Borrull F., Pocurull E., Marcé R.M. Pressurized liquid extraction of pharmaceuticals from sewage-sludge. Journal of Separation Science 2007, 30:979-984.
37. Oller I., Malato S., Sánchez-Pérez J.A. Combination of advanced oxidation processes and biological treatments for wastewater decontamination - a review. Science of The Total Environment 2011, 409:4141-4166.
38. Ort C., Lawrence M.G., Rieckermann J., Joss A. Sampling for pharmaceuticals and personal care products (PPCPs) and illicit drugs in wastewater systems: are your conclusions valid? - a critical review. Environmental Science & Technology 2010, 44:6024-6035.
39. Oulton R.L., Kohn T., Cwiertny D.M. Pharmaceuticals and personal care products in effluent matrices: a survey of transformation and removal during wastewater treatment and implications for wastewater management. Journal of Environmental Monitoring 2010, 12:1956-1978.
40. Radjenović J., Jelić A., Petrović M., Barceló D. Determination of pharmaceuticals in sewage sludge by pressurized liquid extraction (PLE) coupled to liquid chromatography-tandem mass spectrometry. Analytical and Bioanalytical Chemistry 2009, 393:1685-1695.
41. Rúa-Gómez P.C., Püttmann W. Impact of wastewater treatment plant discharge of lidocaine, tramadol, venlafaxine and their metabolites on the quality of surface waters and groundwater. Journal of Environmental Monitoring 2012, 14:1391-1399.
42. Schultz M.M., Furlong E.T. Trace analysis of antidepressants pharmaceuticals and their select degradates in aquatic matrixes by LC/ESI/MS/MS. Analytical Chemistry 2008, 80:1756-1762.
43. Schultz M.M., Furlong E.T., Kolpin D.W., Werner S.L., Schoenfuss H.L., Barber L.B., Blazer V.S., Norris D.O., Vajda A.M. Antidepressants pharmaceuticals in two U.S. effluent-impacted streams: occurrence and fate in water and sediment, and selective uptake in fish neural tissue. Environmental Science & Technology 2010, 44:1918-1925.
44. Servos M.R., Bennie D.T., Burnison B.K., Jurkovic A., McInnis R., Neheli T., Schnell A., Seto P., Smyth S.A., Ternes T.A. Distribution of estrogens, 17β-estradiol and estrone in Canadian municipal wastewater treatment plants. Science of The Total Environment 2005, 336:155-170.
45. Sui Q., Huang J., Deng S., Chen W., Yu G. Seasonal variation in the occurrence and removal of pharmaceuticals and personal care products in different biological wastewater treatment processes. Environmental Science & Technology 2011, 45:3341-3348.
46. Tchobanoglous G., Burton F., Stensel H.D. Wastewater engineering: treatment and reuse. McGraw-Hill Series in Civil and Environmental Engineering 2004, (New-York, London). fourth ed. Metcalf, Eddy (Eds.).
47. Ternes T.A. Occurrence of drugs in German sewage plants and rivers. Water Research 1998, 32(11):3245-3260.
48. Ternes T.A., Joss A., Siegrist H. Scrutinizing pharmaceuticals and personal care products in wastewater treatment. Environmental Science & Technology October 2004, 393A-399A.
49. Ternes T.A., Bonerz M., Hermann N., Löffler D., Keller E., Lacida B.B., Alder A. Determination of pharmaceuticals, iodinated contrast media and musk fragrances in sludge by LC/tandem MS and GC/MS. Journal of Chromatography A 2005, 1067:213-223.
50. Vanderford B.J., Pearson R.A., Rexing D.J., Snyder S.A. Analysis of endocrine disruptors, pharmaceuticals, and personal care products in water using liquid chromatography/tandem mass spectrometry. Analytical Chemistry 2003, 75:6265-6274.
51. Vasskog T., Berger U., Samuelsen P.-J., Kallenborn R., Jensen E. Selective serotonin reuptake inhibitors in sewage influents and effluents from Tromsø, Norway. Journal of Chromatography A 2006, 1115:187-195.
52. Vasskog T., Andersen T., Pedersen-Bjergaard S., Kallenborn R., Jensen E. Occurrence of selective serotonin reuptake inhibitors in sewage and receiving waters at Spitsbergen and in Norway. Journal of Chromatography A 2008, 1185:194-205.
53. Vasskog T., Bergersen O., Andersen T., Jensen E., Eggen T. Depletion of selective serotonin reuptake inhibitors during sewage sludge composting. Waste Management 2009, 29:2808-2815.
54. Viglino L., Prévost M., Sauvé S. High throughput analysis of solid-bound endocrine disruptors by LDTD-MS/MS. Journal of Environmental Monitoring 2011, 13:583-590.
55. Weigel S., Berger U., Jensen E., Kallenborn R., Thorensen H., Hühnerfuss H. Determination of select pharmaceuticals and caffeine in sewage and seawater from Tromsø/Norway with emphasis on ibuprofen and its metabolites. Chemosphere 2004, 56:583-592.
56. Wick A., Fink G., Joss A., Siegrist H., Ternes T.A. Fate of beta blockers and psycho-active drugs in conventional wastewater treatment. Water Research 2009, 43:1060-1074.