Bone degeneration and recovery after early and late bisphosphonate treatment of ovariectomized wistar rats assessed by in vivo micro-computed tomography

Calcified Tissue International

Volumn 82, Issue 3, 2008, Pages 202-211

  Brouwers, J E M ^a   Lambers, F M ^a   Gasser, J A ^b   Van Rietbergen, B ^a   Huiskes, R ^a  

^a EINDHOVEN UNIVERSITY OF TECHNOLOGY   (Netherlands)

^b NOVARTIS PHARMA AG   (Switzerland)

Author keywords

Bisphosphonate; In vivo micro computed tomography; Osteoporosis; Rat

Indexed keywords

BISPHOSPHONIC ACID DERIVATIVE; ZOLEDRONIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE ATROPHY; BONE DENSITY; BONE MASS; BONE STRUCTURE; COMPARATIVE STUDY; COMPUTED TOMOGRAPHY SCANNER; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; EARLY INTERVENTION; FEMALE; FLUORESCENCE ANALYSIS; IN VIVO STUDY; METAPHYSIS; MICRO-COMPUTED TOMOGRAPHY; MORPHOMETRICS; NONHUMAN; OSSIFICATION; OSTEOPOROSIS; OVARIECTOMY; PRIORITY JOURNAL; RAT; SINGLE DRUG DOSE; THERAPY DELAY; TIBIA; TRABECULAR BONE;

ANIMALS; BONE DEMINERALIZATION, PATHOLOGIC; BONE DENSITY CONSERVATION AGENTS; BONE RESORPTION; COMPRESSIVE STRENGTH; DIPHOSPHONATES; DISEASE MODELS, ANIMAL; ELASTICITY; FEMALE; IMIDAZOLES; OSTEOPOROSIS; OVARIECTOMY; RATS; RATS, WISTAR; STRESS, MECHANICAL; TIBIA; TOMOGRAPHY, X-RAY COMPUTED;

EID: 41049086665     PISSN: 0171967X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00223-007-9084-3     Document Type: Article

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