Preventive effects of the anti-vasospasm agent via the regulation of the Rho-kinase pathway on the development of steroid-induced osteonecrosis in rabbits

Bone

Volumn 53, Issue 2, 2013, Pages 329-335

  Ikemura, Satoshi ^a   Yamamoto, Takuaki ^a   Motomura, Goro ^a   Yamaguchi, Ryosuke ^a   Zhao, Garida ^a   Iwasaki, Kenyu ^a   Iwamoto, Yukihide ^a  

^a KYUSHU UNIVERSITY   (Japan)

Author keywords

Corticosteroid; Femoral head; Osteonecrosis; Rabbit; Vasospasm

Indexed keywords

APOLIPOPROTEIN E; ENDOTHELIAL NITRIC OXIDE SYNTHASE; ENDOTHELIN A RECEPTOR; FASUDIL; FIBRINOGEN; METHYLPREDNISOLONE; RHO KINASE; THROMBIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; BONE MARROW; BONE NECROSIS; CONTINUOUS INFUSION; CONTROLLED STUDY; DRUG HALF LIFE; ENZYME REGULATION; FEMUR; HISTOPATHOLOGY; HUMERUS; IMMUNOHISTOCHEMISTRY; INCIDENCE; MALE; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; PATHOGENESIS; PROTEIN EXPRESSION; PROTEOMICS; RABBIT; SMOOTH MUSCLE; TREATMENT OUTCOME; VASOSPASM;

1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE; ADRENAL CORTEX HORMONES; ANIMALS; MALE; METHYLPREDNISOLONE; OSTEONECROSIS; RABBITS; RHO-ASSOCIATED KINASES; STEROIDS;

EID: 84872813183     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2012.12.050     Document Type: Article

References (34)

1. Assouline-Dayan Y., Chang C., Greenspan A., Shoenfeld Y., Gershwin M.E. Pathogenesis and natural history of osteonecrosis. Semin Arthritis Rheum 2002, 32:94-124.
2. Ortiguera C.J., Pulliam I.T., Cabanela M.E. Total hip arthroplasty for osteonecrosis: matched-pair analysis of 188 hips with long-term follow-up. J Arthroplasty 1999, 14:21-28.
3. Mont M.A., Hungerford D.S. Non-traumatic avascular necrosis of the femoral head. J Bone Joint Surg Am 1995, 77:459-473.
4. Yamamoto T., Irisa T., Sugioka Y., Sueishi K. Effects of pulse methylprednisolone on bone and marrow tissues: corticosteroid-induced osteonecrosis in rabbits. Arthritis Rheum 1997, 40:2055-2064.
5. Miyanishi K., Yamamoto T., Irisa T., Yamashita A., Jingushi S., Noguchi Y., et al. Bone marrow fat cell enlargement and a rise in intraosseous pressure in steroid-treated rabbits with osteonecrosis. Bone 2002, 30:185-190.
6. Motomura G., Yamamoto T., Miyanishi K., Jingushi S., Iwamoto Y. Combined effects of an anticoagulant and a lipid-lowering agent on the prevention of steroid-induced osteonecrosis in rabbits. Arthritis Rheum 2004, 50:3387-3391.
7. Ichiseki T., Matsumoto T., Nishino M., Kaneuji A., Katsuda S. Oxidative stress and vascular permeability in steroid-induced osteonecrosis model. J Orthop Sci 2004, 9:509-515.
8. Kuribayashi M., Fujioka M., Takahashi K.A., Arai Y., Ishida M., Goto T., et al. Vitamin E prevents steroid-induced osteonecrosis in rabbits. Acta Orthop 2010, 81:154-160.
9. Yasue H., Omote S., Takizawa A., Takizawa A., Nagao M. Coronary arterial spasm in ischemic heart disease and its pathogenesis. Circ Res 1983, 52:147-152.
10. Kawano H., Node K. The role of vascular failure in coronary artery spasm. J Cardiovasc 2011, 57:2-7.
11. Kimura K., Ito M., Amano M., Chihara K., Fukata Y., Nakafuku M., et al. Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase). Science 1996, 273:245-248.
12. Fukata Y., Amano M., Kaibuchi K. Rho-Rho-kinase pathway in smooth muscle contraction and cytoskeletal reorganization of non-muscle cells. Trends Pharmacol Sci 2001, 22:32-39.
13. Otsuka T., Ibuki C., Suzuki T., Ishii K., Kodani E., Atarashi H., et al. Vasodilatory effect of subsequent administration of fasudil, a rho-kinase inhibitor, surpasses that of nitroglycerin at the concentric coronary stenosis in patients with stable angina pectoris. Circ J 2006, 70:402-408.
14. Satoh S., Hitomi A., Ikegaki I., Kawasaki K., Nakazono O., Iwasaki M., et al. Amelioration of endothelial damage/dysfunction is a possible mechanism for the neuroprotective effects of Rho-kinase inhibitors against ischemic brain damage. Brain Res Bull 2010, 81:191-195.
15. Toshima Y., Satoh S., Ikegaki I., Asano T. A new model of cerebral microthrombosis in rat and the neuroprotective effect of a Rho-kinase inhibitor. Stroke 2000, 31:2245-2250.
16. Shibuya M., Hirai S., Seto M., Satoh S., Ohtomo E. Fasudil Ischemic Stroke Study Group. Effects of fasudil in acute ischemic stroke: results of a prospective placebo-controlled double-blind trial. J Neurol Sci 2005, 238:31-39.
17. Herrera E.A., Camm E.J., Cross C.M., Mullender J.L., Wooding F.B., Giussani D.A. Morphological and functional alterations in the aorta of the chronically hypoxic fetal rat. J Vasc Res 2012, 49:50-58.
18. Gangopahyay A., Oran M., Bauer E.M., Wertz J.W., Comhair S.A., Erzurum S.C., et al. Bone morphogenetic protein receptor II is a novel mediator of endothelial nitric-oxide synthase activation. J Biol Chem 2011, 286:33134-33140.
19. Tsikas D. Methods of quantitative analysis of the nitric oxide metabolites and nitrate in human biological fluids. Free Radic Res 2005, 39:795-815.
20. Mann M., Pandey A. Use of mass spectrometry-derived data to annotate nucleotide and protein sequence databases. Trends Biochem Sci 2001, 26:54-61.
21. Yamanaka H., Takeyoshi M., Minobe Y., Yakabe Y., Takatsuki M., Sato H. Comprehensive identification of cytochrome p450 isoforms from solubility-based fractionated rat liver microsomes. Drug Metab Lett 2007, 1:281-286.
22. Perkins D.N., Pappin D.J., Creasy D.M., Cottrell J.S. Probability-based protein identification by searching sequence databases using mass spectrometry data. Electrophoresis 1999, 20:3551-3567.
23. Hirano K., Tsutsui H., Sugioka Y., Sueishi K. Histopathologic alterations of retinacular vessels and osteonecrosis. Clin Orthop 1997, 342:192-204.
24. Kishi F., Minami K., Okishima N., Murakami M., Mori S., Yano M., et al. Novel 31-amino-acid-length endothelins cause constriction of vascular smooth muscle. Biochem Biophys Res Commun 1998, 248:387-390.
25. Agapitov A.V., Haynes W.G. Role of endothelin in cardiovascular disease. J Renin Angiotensin Aldosterone 2002, 3:1-15.
26. Spratt J.C., Goddard J., Patel N., Strachan F.E., Rankin A.J., Webb D.J. Systemic ETA receptor antagonism with BQ-123 blocks ET-1 induced forearm vasoconstriction and decreases peripheral vascular resistance in healthy men. Br J Pharmacol 2001, 134:648-654.
27. Kumar A., Morrison S., Gulati A. Effect of ETA receptor antagonists on cardiovascular responses induced by centrally administered sarafotoxin 6b: role of sympathetic nervous system. Peptides 1997, 18:855-864.
28. Iuchi T., Akaike M., Mitsui T., Ohshima Y., Shintani Y., Azuma H., et al. Glucocorticoid excess induces superoxide production in vascular endothelial cells and elicits vascular endothelial dysfunction. Circ Res 2003, 92:81-87.
29. Kerachian M.A., Séguin C., Harvey E.J. Glucocorticoids in osteonecrosis of the femoral head: a new understanding of the mechanisms of action. J Steroid Biochem Mol Biol 2009, 114:121-128.
30. Uehata M., Ishizaki T., Satoh H., Ono T., Kawahara T., Morishita T., et al. Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension. Nature 1997, 389:990-994.
31. Yamanaka H., Yakabe Y., Saito K., Sekijima M., Shirai T. Quantitative proteomic analysis of rat liver for carcinogenicity prediction in a 28-day repeated dose study. Proteomics 2007, 7:781-795.
32. Miyanishi K., Yamamoto T., Irisa T., Yamashita A., Jingushi S., Noguchi Y., et al. A high low-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio as a potential risk factor for corticosteroid-induced osteonecrosis in rabbits. Rheumatology (Oxford) 2001, 40:196-201.
33. Ichiseki T., Kaneuji A., Katsuda S., Ueda Y., Sugimori T., Matsumoto T. DNA oxidation injury in bone early after steroid administration is involved in the pathogenesis of steroid-induced osteonecrosis. Rheumatology (Oxford) 2005, 44:456-460.
34. Nishida K., Yamamoto T., Motomura G., Jingushi S., Iwamoto Y. Pitavastatin may reduce risk of steroid-induced osteonecrosis in rabbits: a preliminary histological study. Clin Orthop 2008, 466:1054-1058.