Synchrotron X-ray interlaced microbeams suppress paroxysmal oscillations in neuronal networks initiating generalized epilepsy

Neurobiology of Disease

Volumn 51, Issue , 2013, Pages 152-160

  Pouyatos, Benoît ^a   Serduc, Raphaël ^a   Chipaux, Mathilde ^b,c   Chabrol, Tanguy ^a   Bräuer Krisch, Elke ^d   Nemoz, Christian ^d   Mathieu, Hervé ^a   David, Olivier ^a   Renaud, Luc ^e   Prezado, Yolanda ^d   Laissue, Jean Albert ^f   Estève, François ^a   Charpier, Stéphane ^c   Depaulis, Antoine ^a  

^a GRENOBLE INSTITUT DES NEUROSCIENCES   (France)

^b FONDATION OPHTALMOLOGIQUE ADOLPHE DE ROTHSCHILD   (France)

^c CNRS   (France)

^d EUROPEAN SYNCHROTRON RADIATION FACILITY   (France)

^e Brain and Cognition Research Center in Toulouse   (France)

^f UNIVERSITY OF BERN   (Switzerland)

Author keywords

Animal model; Epilepsy; In vivo; Intracellular recordings; Radiotherapy; Spike wave discharges; Synchrotron X ray microbeams

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTICONVULSANT THERAPY; ARTICLE; BEAM THERAPY; BRAIN REGION; CONTROLLED STUDY; ELECTRIC POTENTIAL; FEMALE; GENERALIZED EPILEPSY; HISTOPATHOLOGY; IN VIVO STUDY; INTERLACED ARRAYS OF MICROBEAM; NERVE CELL NETWORK; NEUROANATOMY; NONHUMAN; OSCILLATION; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; RADIATION DOSE; RAT; SOMATOSENSORY CORTEX; SYNAPTIC POTENTIAL; SYNCHROTRON RADIATION; THALAMUS;

ANIMALS; DISEASE MODELS, ANIMAL; ELECTROENCEPHALOGRAPHY; EPILEPSY, ABSENCE; FEMALE; NERVE NET; RATS; SOMATOSENSORY CORTEX; X-RAY THERAPY;

EID: 84872806062     PISSN: 09699961     EISSN: 1095953X     Source Type: Journal    
DOI: 10.1016/j.nbd.2012.11.005     Document Type: Article

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