Assessing breast cancer margins ex vivo using aqueous quantum-dot-molecular probes

International Journal of Surgical Oncology

Volumn 2012, Issue , 2012, Pages

  Au, Giang H T ^a   Shih, Wan Y ^a   Shih, Wei Heng ^b   Mejias, Linette ^c   Swami, Vanlila K ^c   Wasko, Kimberly ^c   Brooks, Ari D ^c  

^a DREXEL UNIVERSITY   (United States)

^b Drexel University   (United States)

^c DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84872803391     PISSN: 20901402     EISSN: 20901410     Source Type: Journal    
DOI: 10.1155/2012/861257     Document Type: Article

References (61)

1. Breast Cancer Overview. American Cancer Society; 2012 http://www.cancer.org/Cancer/BreastCancer/OverviewGuide/breast-cancer-overview- key-statistics
2. Nguyen F. T., Zysk A. M., Chaney E. J., Kotynek J. G., Oliphant U. J., Bellafiore F. J., Rowland K. M., Johnson P. A., Boppart S. A., Intraoperative evaluation of breast tumor margins with optical coherence tomography. Cancer Research 2009 69 22 8790 8796 2-s2.0-72249122937 10.1158/0008-5472.CAN-08-4340
3. Balch G. C., Mithani S. K., Simpson J. F., Kelley M. C., Gwin J., Bland K., Accuracy of intraoperative gross examination of surgical margin status in women undergoing partial mastectomy for breast malignancy. American Surgeon 2005 71 1 22 28 2-s2.0-14944347508 (Pubitemid 43073515)
4. Cabioglu N., Hunt K. K., Sahin A. A., Kuerer H. M., Babiera G. V., Singletary S. E., Whitman G. J., Ross M. I., Ames F. C., Feig B. W., Buchholz T. A., Meric-Bernstam F., Role for intraoperative margin assessment in patients undergoing breast-conserving surgery. Annals of Surgical Oncology 2007 14 4 1458 1471 2-s2.0-34047214302 10.1245/s10434-006-9236-0 (Pubitemid 46536814)
5. Kurniawan E. D., Wong M. H., Windle I., Rose A., Mou A., Buchanan M., Collins J. P., Miller J. A., Gruen R. L., Mann G. B., Predictors of surgical margin status in breast-conserving surgery within a breast screening program. Annals of Surgical Oncology 2008 15 9 2542 2549 2-s2.0-50049131073 10.1245/s10434-008-0054-4
6. Poggi M. M., Danforth D. N., Sciuto L. C., Smith S. L., Steinberg S. M., Liewehr D. J., Menard C., Lippman M. E., Lichter A. S., Altemus R. M., Eighteen-year results in the treatment of early breast carcinoma with mastectomy versus breast conservation therapy: the National Cancer Institute randomized trial. Cancer 2003 98 4 697 702 2-s2.0-0042071601 10.1002/cncr.11580 (Pubitemid 36959264)
7. Chagpar A., Yen T., Sahin A., Hunt K. K., Whitman G. J., Ames F. C., Ross M. I., Meric-Bernstam F., Babiera G. V., Singletary S. E., Kuerer H. M., Intraoperative margin assessment reduces reexcision rates in patients with ductal carcinoma in situ treated with breast-conserving surgery. American Journal of Surgery 2003 186 4 371 377 2-s2.0-10744227387 10.1016/S0002-9610(03) 00264-2 (Pubitemid 38368613)
8. Abe O., Abe R., Enomoto K., Effects of radiotherapy and of differences in the extent of surgery for early breast cancer on local recurrence and 15-year survival: an overview of the randomised trials. The Lancet 2005 366 9503 2087 2106 10.1016/S0140-6736(05)67887-7 (Pubitemid 41797643)
9. Kell M. R., Dunne C., Burke J. P., Morrow M., Effect of margin status on local recurrence after breast conservation and radiation therapy for ductal carcinoma in situ. Journal of Clinical Oncology 2009 27 10 1615 1620 2-s2.0-63749086807 10.1200/JCO.2008.17.5182
10. Cao D., Lin C., Woo S. H., Vang R., Tsangaris T. N., Argani P., Separate cavity margin sampling at the time of initial breast lumpectomy significantly reduces the need for reexcisions. American Journal of Surgical Pathology 2005 29 12 1625 1632 2-s2.0-33644789703
11. Veronesi U., Cascinelli N., Mariani L., Greco M., Saccozzi R., Luini A., Aguilar M., Marubini E., Twenty-year follow-up of a randomized study comparing breast-conserving surgery with radical mastectomy for early breast cancer. The New England Journal of Medicine 2002 347 16 1227 1232 2-s2.0-0037126350 10.1056/NEJMoa020989 (Pubitemid 35176241)
12. Valdes E. K., Boolbol S. K., Cohen J. M., Feldman S. M., Intra-operative touch preparation cytology; does it have a role in re-excision lumpectomy? Annals of Surgical Oncology 2007 14 3 1045 1050 2-s2.0-33847368964 10.1245/s10434-006-9263-x (Pubitemid 46348828)
13. Olson T. P., Harter J., Muñoz A., Mahvi D. M., Breslin T. M., Frozen section analysis for intraoperative margin assessment during breast-conserving surgery results in low rates of re-excision and local recurrence. Annals of Surgical Oncology 2007 14 10 2953 2960 2-s2.0-34648832084 10.1245/s10434-007-9437-1 (Pubitemid 47460626)
14. Dener C., Inan A., Sen M., Demirci S., Intraoperative frozen section for margin assessment in breast conserving surgery. Scandinavian Journal of Surgery 2009 98 1 34 40 2-s2.0-67649126324
15. Pappo I., Spector R., Schindel A., Morgenstern S., Sandbank J., Leider L. T., Schneebaum S., Lelcuk S., Karni T., Diagnostic performance of a novel device for real-time margin assessment in lumpectomy specimens. Journal of Surgical Research 2010 160 2 277 281 2-s2.0-77950917979 10.1016/j.jss.2009.02. 025
16. Izuishi K., Tajiri H., Fujii T., Boku N., Ohtsu A., Ohnishi T., Ryu M., Kinoshita T., Yoshida S., The histological basis of detection of adenoma and cancer in the colon by autofluorescence endoscopic imaging. Endoscopy 1999 31 7 511 516 2-s2.0-0032850907 10.1055/s-1999-57 (Pubitemid 29457226)
17. De Veld D. C. G., Witjes M. J. H., Sterenborg H. J. C. M., Roodenburg J. L. N., The status of in vivo autofluorescence spectroscopy and imaging for oral oncology. Oral Oncology 2005 41 2 117 131 2-s2.0-13444261941 10.1016/j.oraloncology.2004.07.007 (Pubitemid 40202877)
18. Singletary S. E., Surgical margins in patients with early-stage breast cancer treated with breast conservation therapy. American Journal of Surgery 2002 184 5 383 393 2-s2.0-0036845433 10.1016/S0002-9610(02)01012-7 (Pubitemid 35335942)
19. Nguyen Q. T., Olson E. S., Aguilera T. A., Jiang T., Scadeng M., Ellies L. G., Tsien R. Y., Surgery with molecular fluorescence imaging using activatable cell-penetrating peptides decreases residual cancer and improves survival. Proceedings of the National Academy of Sciences of the United States of America 2010 107 9 4317 4322 2-s2.0-77749254873 10.1073/pnas.0910261107
20. van Dam G. M., Themelis G., Crane L. M. A., Intraoperative tumor-specific fluorescence imaging in overaian cancer by folate receptor-a targeting: first in-human results. Nature Medicine 2011 17 10 1315 1320
21. Carrilho C., Cantel M., Gouveia P., David L., Simple mucin-type carbohydrate antigens (Tn, sialosyl-Tn, T and sialosyl-T) and gp 230 mucin-like glycoprotein are candidate markers for neoplastic transformation of the human cervix. Virchows Archiv 2000 437 2 173 179 2-s2.0-0033880054 (Pubitemid 30623577)
22. Kishikawa T., Ghazizadeh M., Sasaki Y., Springer G. F., Specific role of T and Tn tumor-associated antigens in adhesion between a human breast carcinoma cell line and a normal human breast epithelial cell line. Japanese Journal of Cancer Research 1999 90 3 326 332 2-s2.0-0032915391 (Pubitemid 29164023)
23. Imai J., Ghazizadeh M., Naito Z., Asano G., Immunohistochemical expression of T, Tn and sialyl-Tn antigens and clinical outcome in human breast carcinoma. Anticancer Research 2001 21 2 1327 1334 2-s2.0-0035003195 (Pubitemid 32494142)
24. Blixt O., Lavrova O. I., Mazurov D. V., Cló E., Kračun S. K., Bovin N. V., Filatov A. V., Analysis of Tn antigenicity with a panel of new IgM and IgG1 monoclonal antibodies raised against leukemic cells. Glycobiology 2012 22 4 529 542 10.1093/glycob/cwr178
25. Zhuang D., Yousefi S., Dennis J. W., Tn antigen and UDP-Gal:GalNAc alpha-R beta 1-3Galactosyltransferase expression in human breast carcinoma. Cancer Biochemistry Biophysics 1991 12 3 185 198 2-s2.0-0026254563
26. Ju T., Lanneau G. S., Gautam T., Wang Y., Xia B., Stowell S. R., Willard M. T., Wang W., Xia J. Y., Zuna R. E., Laszik Z., Benbrook D. M., Hanigan M. H., Cummings R. D., Human tumor antigens Tn and sialyl Tn arise from mutations in Cosmc. Cancer Research 2008 68 6 1636 1646 2-s2.0-40949133707 10.1158/0008-5472.CAN-07-2345 (Pubitemid 351416547)
27. Ju T., Otto V. I., Cummings R. D., The Tn antigena-structural simplicity and biological complexity. Angewandte Chemie-International Edition 2011 50 8 1770 1791 2-s2.0-79951801155 10.1002/anie.201002313
28. Konska G., Guerry M., Caldefie-Chezet F., De Latour M., Guillot J., Study of the expression of Tn antigen in different types of human breast cancer cells using VVA-B4 lectin. Oncology Reports 2006 15 2 305 310 2-s2.0-33744504505
29. Springer G. F., Immunoreactive T and Tn epitopes in cancer diagnosis, prognosis, and immunotherapy. Journal of Molecular Medicine 1997 75 8 594 602 2-s2.0-0030848719 10.1007/s001090050144 (Pubitemid 27373602)
30. Konska G., Guillot J., De Latour M., Fonck Y., Expression of Tn antigen and N-acetyllactosamine residues in malignant and benign human breast tumors detected by lectins and monoclonal antibody 83D4. International Journal of Oncology 1998 12 2 361 367 2-s2.0-0031907306 (Pubitemid 28064862)
31. Demichelis S. O., Alberdi C. G., Servi W. J., Isla-Larrain M. T., Segal-Eiras A., Croce M. V., Comparative immunohistochemical study of MUC1 and carbohydrate antigens in breast benign disease and normal mammary gland. Applied Immunohistochemistry and Molecular Morphology 2010 18 1 41 50 2-s2.0-76149118772 10.1097/PAI.0b013e3181ac1c20
32. Galonić D. P., Gin D. Y., Chemical glycosylation in the synthesis of glycoconjugate antitumour vaccines. Nature 2007 446 7139 1000 1007 2-s2.0-34247853422 10.1038/nature05813 (Pubitemid 46691044)
33. Slovin S. F., Keding S. J., Ragupathi G., Carbohydrate vaccines as immunotherapy for cancer. Immunology and Cell Biology 2005 83 4 418 428 2-s2.0-22944474953 10.1111/j.1440-1711.2005.01350.x (Pubitemid 41044620)
34. Konska G., Vissac C., Zagla K., Chezet F., Vasson M. P., Bernard-Gallon D., Guillot J., Ultrastructural localization of binding sites for PNA and VVA-B(4) lectins in human breast cancer cell lines detected by confocal fluorescence microscopy. International Journal of Oncology 2002 21 5 1009 1014 2-s2.0-0036834228
35. Gao X., Cui Y., Levenson R. M., Chung L. W. K., Nie S., In vivo cancer targeting and imaging with semiconductor quantum dots. Nature Biotechnology 2004 22 8 969 976 2-s2.0-3543022686 10.1038/nbt994 (Pubitemid 39014473)
36. Zhao Q., Jiang H., Cao Z., Yang L., Mao H., Lipowska M., A handhold fluorescene molecular tomography system for interoperative optical imaging of tumor margins. Medical Physics 2011 38 11 5873 5879
37. Zhou M., Ghosh I., Quantum dots and peptides: a bright future together. Biopolymers 2007 88 3 325 339 2-s2.0-34250683760 10.1002/bip.20655 (Pubitemid 46732418)
38. Watanabe M., Fujioka K., Akiyama N., Takeyama H., Manabe N., Yamamoto K., Manome Y., Conjugation of quantum dots and JT95 IgM monoclonal antibody for thyroid carcinoma without abolishing the specificity and activity of the antibody. IEEE Transactions on Nanobioscience 2011 10 1 30 35 2-s2.0-79955622654 10.1109/TNB.2011.2125800
39. Xia Z., Xing Y., So M. K., Koh A. L., SInclair R., Rao J., Multiplex detecion of protease activity with quantum dor nano sensors preapred by interinmediated specific bioconjugation. Analytical Chemistry 2008 80 8649 8655
40. Wu X., Liu H., Liu J., Haley K. N., Treadway J. A., Larson J. P., Ge N., Peale F., Bruchez M. P., Immunofluorescent labeling of cancer marker Her2 and other cellular targets with semiconductor quantum dots. Nature Biotechnology 2003 21 1 41 46 10.1038/nbt764 (Pubitemid 36055825)
41. Jaiswal J. K., Goldman E. R., Mattoussi H., Simon S. M., Use of quantum dots for live cell imaging. Nat Methods 2004 1 1 73 78 2-s2.0-24044518772
42. Au G. H. T., Shih W. Y., Tseng S. J., Shih W. H., Aqueoues CdPbS quantum dots for near-infrared imaging. Nanotechnology 2012 23 275601
43. Wu C. S., Oo M. K. K., Cupps J. M., Fan X., Robust silica-coated quantum dot-molecular beacon for high sensitive DNA detection. Biosen Bioelectron 2011 26 3870
44. Kim S., Lim Y. T., Soltesz E. G., De Grand A. M., Lee J., Nakayama A., Parker J. A., Mihaljevic T., Laurence R. G., Dor D. M., Cohn L. H., Bawendi M. G., Frangioni J. V., Near-infrared fluorescent type II quantum dots for sentinel lymph node mapping. Nature Biotechnology 2004 22 1 93 97 2-s2.0-0347473808 10.1038/nbt920 (Pubitemid 38057962)
45. Wang J., Yong W. H., Sun Y., Vernier P. T., Koeffler H. P., Gundersen M. A., Marcu L., Receptor-targeted quantum dots: fluorescent probes for brain tumor diagnosis. Journal of Biomedical Optics 2007 12 4 044021 10.1117/1.2764463 (Pubitemid 350066427)
46. Zhang C. Y., Hu J., Single quantum dot-based nanosensor for multiple DNA detection. Analytical Chemistry 2010 82 5 1921 1927 2-s2.0-77749305092 10.1021/ac9026675
47. Cady N. C., Quantum dot molecular beacons for DNA detection. Methods in Molecular Biology 2009 544 3 367 379
48. Kim J. H., Chaudhary S., Ozkan M., Multicolour hybrid nanoprobes of molecular beacon conjugated quantum dots: FRET and gel electrophoresis assisted target DNA detection. Nanotechnology 2007 18 19 2-s2.0-34249020474 10.1088/0957-4484/18/19/195105 195105 (Pubitemid 46786428)
49. Papagiannaros A., Upponi J., Hartner W., Mongayt D., Levchenko T., Torchilin V., Quantum dot loaded immunomicelles for tumor imaging. BMC Medical Imaging 2010 10, article 22 2-s2.0-77957924571 10.1186/1471-2342-10-22
50. Jiang W., Papa E., Fischer H., Mardyani S., Chan W. C. W., Semiconductor quantum dots as contrast agents for whole animal imaging. Trends in Biotechnology 2004 22 12 607 609 2-s2.0-8144229655 10.1016/j.tibtech.2004.10.012 (Pubitemid 39473205)
51. Li H., Shih W. Y., Shih W. H., Non-heavy-metal ZnS quantum dots with bright blue photoluminescence by a one-step aqueous synthesis. Nanotechnology 2007 18 20 2-s2.0-34247488822 10.1088/0957-4484/18/20/205604 205604 (Pubitemid 46663869)
52. Li H., Shih W. Y., Shih W. H., Synthesis and characterization of aqueous carboxyl-capped CdS quantum dots for bioapplications. Industrial and Engineering Chemistry Research 2007 46 7 2013 2019 2-s2.0-34247153474 10.1021/ie060963s (Pubitemid 46588075)
53. Ramanujam N., Fluorescence spectroscopy of neoplastic and non-neoplastic tissues. Neoplasia 2000 2 1-2 89 117 2-s2.0-0034050985 (Pubitemid 30123183)
54. Cohen E., Ophir I., Shaul Y. B., Induced differentiation in HT29, a human colon adenocarcinoma cell line. Journal of Cell Science 1999 112 16 2657 2666 2-s2.0-0032821972 (Pubitemid 29429789)
55. Li H., Shih W. H., Shih W. Y., Chen L., Tseng S. J., Tang S. C., Transfection of aqueous CdS quantum dots using polyethylenimine. Nanotechnology 2008 19 47 2-s2.0-58149252199 10.1088/0957-4484/19/47/475101 475101
56. Burkholder H. C., Witherspoon L. E., Burns R. P., Horn J. S., Biderman M. D., Breast surgery techniques: preoperative bracketing wire localization by surgeons. American Surgeon 2007 73 6 574 578 2-s2.0-34548552862 (Pubitemid 351396650)
57. Wallace A. M., Daniel B. L., Jeffrey S. S., Birdwell R. L., Nowels K. W., Dirbas F. M., Schraedley-Desmond P., Ikeda D. M., Rates of reexcision for breast cancer after magnetic resonance imaging-guided bracket wire localization. Journal of the American College of Surgeons 2005 200 4 527 537 2-s2.0-15944371880 10.1016/j.jamcollsurg.2004.12.013 (Pubitemid 40432320)
58. Pleijhuis R. G., Graafland M., De Vries J., Bart J., De Jong J. S., Van Dam G. M., Obtaining adequate surgical margins in breast-conserving therapy for patients with early-stage breast cancer: current modalities and future directions. Annals of Surgical Oncology 2009 16 10 2717 2730 2-s2.0-73349137018 10.1245/s10434-009-0609-z
59. Law T. T., Kwong A., Surgical margins in breast conservation therapy: how much should we excise? Southern Medical Journal 2009 102 12 1234 1237 2-s2.0-73949094364 10.1097/SMJ.0b013e3181bfd420
60. Wilke L. G., Brown J. Q., Bydlon T. M., Kennedy S. A., Richards L. M., Junker M. K., Gallagher J., Barry W. T., Geradts J., Ramanujam N., Rapid noninvasive optical imaging of tissue composition in breast tumor margins. American Journal of Surgery 2009 198 4 566 574 2-s2.0-70349466659 10.1016/j.amjsurg.2009.06.018
61. Themelis G., Yoo J. S., Soh K. S., Schulz R., Ntziachristos V., Real-time intraoperative fluorescence imaging system using light-absorption correction. Journal of Biomedical Optics 2009 14 6 064012 2-s2.0-77950359684