An orthopedic tissue adhesive for targeted delivery of intraoperative biologics

Journal of Orthopaedic Research

Volumn 31, Issue 3, 2013, Pages 392-400

  Simson, Jacob ^a   Crist, Joshua ^a   Strehin, Iossif ^a   Lu, Qiaozhi ^a   Elisseeff, Jennifer H ^a  

^a Johns Hopkins University   (United States)

Author keywords

bone marrow; intraoperative biologics; osteogenesis; PRP; tissue adhesive

Indexed keywords

ALKALINE PHOSPHATASE; BIOMATERIAL; CALCIUM; CHONDROITIN SULFATE SUCCINIMIDYL SUCCINATE; CYANOACRYLATE; OSTEOCALCIN; TRANSCRIPTION FACTOR RUNX2; UNCLASSIFIED DRUG;

ARTICLE; BIOCOMPATIBILITY; BONE DEVELOPMENT; BONE MARROW; CELL ENCAPSULATION; CELL VIABILITY; CULTURE MEDIUM; GELATION; GENE EXPRESSION; HUMAN; HUMAN CELL; HYDROGEL; IMMUNOHISTOCHEMISTRY; IMPLANT DELIVERY DEVICE; MESENCHYMAL STEM CELL; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STEM CELL; THROMBOCYTE RICH PLASMA; UPREGULATION;

BONE MARROW; BONE MARROW CELLS; CELL SURVIVAL; CHONDROITIN SULFATES; GENE EXPRESSION; HUMANS; HYDROGEL; INTRAOPERATIVE PERIOD; MATERIALS TESTING; PLATELET-RICH PLASMA; REGENERATION; SUCCINIMIDES; TISSUE ADHESIVES; TISSUE ENGINEERING;

EID: 84872791906     PISSN: 07360266     EISSN: 1554527X     Source Type: Journal    
DOI: 10.1002/jor.22247     Document Type: Article

References (50)

1. Alsousou J, Thompson M, Hulley P, et al. 2009. The biology of platelet-rich plasma and its application in trauma and orthopaedic surgery: a review of the literature. J Bone Joint Surg Br 91: 987-996.
2. Ishida K, Kuroda R, Miwa M, et al. 2007. The regenerative effects of platelet-rich plasma on meniscal cells in vitro and its in vivo application with biodegradable gelatin hydrogel. Tissue Eng 13: 1103-1112.
3. Murray MM, Spindler KP, Abreu E, et al. 2007. Collagen-platelet rich plasma hydrogel enhances primary repair of the porcine anterior cruciate ligament. J Orthop Res 25: 81-91.
4. Akeda K, An Hs, Okuma M, et al. 2006. Platelet-rich plasma stimulates porcine articular chondrocyte proliferation and matrix biosynthesis. Osteoarthritis Cartilage 14: 1272-1280.
5. Marx RE, Carlson ER, Eichstaedt RM, et al. 1998. Platelet-rich plasma: growth factor enhancement for bone grafts. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 85: 638-646.
6. Caplan AI, Dennis JE,. 2006. Mesenchymal stem cells as trophic mediators. J Cell Biochem 98: 1076-1084.
7. De Jonge S, De Vos RJ, Weir A, et al. 2011. One-year follow-up of platelet-rich plasma treatment in chronic Achilles tendinopathy: a double-blind randomized placebo-controlled trial. Am J Sports Med 39: 1623-1629.
8. Creaney L, Wallace A, Curtis M, et al. 2011. Growth factor-based therapies provide additional benefit beyond physical therapy in resistant elbow tendinopathy: a prospective, single-blind, randomised trial of autologous blood injections versus platelet-rich plasma injections. Br J Sports Med 45: 966-971.
9. Lin SS, Landesberg R, Chin HS, et al. 2006. Controlled release of PRP-derived growth factors promotes osteogenic differentiation of human mesenchymal stem cells. Conf Proc IEEE Eng Med Biol Soc 1: 4358-4361.
10. Rai B, Oest ME, Dupont KM, et al. 2007. Combination of platelet-rich plasma with polycaprolactone-tricalcium phosphate scaffolds for segmental bone defect repair. J Biomed Mater Res A 81: 888-899.
11. Sarkar MR, Augat P, Shefelbine SJ, et al. 2006. Bone formation in a long bone defect model using a platelet-rich plasma-loaded collagen scaffold. Biomaterials 27: 1817-1823.
12. Hoemann CD, Hurtig M, Rossomacha E, et al. 2005. Chitosan-glycerol phosphate/blood implants improve hyaline cartilage repair in ovine microfracture defects. J Bone Joint Surg Am 87: 2671-2686.
13. Everts PA, Knape JT, Weibrich G, et al. 2006. Platelet-rich plasma and platelet gel: a review. J Extra Corpor Technol 38: 174-187.
14. Marx RE,. 2001. Platelet-rich plasma (PRP): what is PRP and what is not PRP? Implant Dent 10: 225-228.
15. Thor A, Franke-Stenport V, Johansson CB, et al. 2007. Early bone formation in human bone grafts treated with platelet-rich plasma: preliminary histomorphometric results. Int J Oral Maxillofac Surg 36: 1164-1171.
16. Han B, Woodell-May J, Ponticiello M, et al. 2009. The effect of thrombin activation of platelet-rich plasma on demineralized bone matrix osteoinductivity. J Bone Joint Surg Am 91: 1459-1470.
17. Harrison S, Vavken P, Kevy S, et al. 2011. Platelet activation by collagen provides sustained release of anabolic cytokines. Am J Sports Med 39: 729-734.
18. Strehin I, Nahas Z, Arora K, et al. 2010. A versatile pH sensitive chondroitin sulfate-PEG tissue adhesive and hydrogel. Biomaterials 31: 2788-2797.
19. Moss M, Kruger GO, Reynolds DC,. 1965. The effect of chondroitin sulfate on bone healing. Oral Surg Oral Med Oral Pathol 20: 795-801.
20. Bouvier M, Couble ML, Hartmann DJ, et al. 1990. Ultrastructural and immunocytochemical study of bone-derived cells cultured in three-dimensional matrices: influence of chondroitin-4 sulfate on mineralization. Differentiation 45: 128-137.
21. Van Sysante JLC, Pieper J, Buma P, et al. 2001. Linkage of chondroitin-sulfate to type I collagen scaffolds stimulates the bioactivity of seeded chondrocytes in vitro. Biomaterials 22: 2359-2369.
22. Wollenweber M, Domaschke H, Hanke T, et al. 2006. Mimicked bioartificial matrix containing chondroitin sulphate on a textile scaffold of poly(3-hydroxybutyrate) alters the differentiation of adult human mesenchymal stem cells. Tissue Eng 12: 345-359.
23. Varghese S, Hwang NS, Canver AC, et al. 2008. Chondroitin sulfate based niches for chondrogenic differentiation of mesenchymal stem cells. Matrix Biol 27: 12-21.
24. Strehin I, Ambrose WM, Schein O, et al. 2009. Synthesis and characterization of a chondroitin sulfate-polyethylene glycol corneal adhesive. J Cataract Refract Surg 35: 567-576.
25. Nagata MJ, Messora MR, Furlaneto FA, et al. 2010. Effectiveness of two methods for preparation of autologous platelet-rich plasma: an experimental study in rabbits. Eur J Dent 4: 395-402.
26. Lee H, Yu C, Chansakul T, et al. 2008. Enhanced chondrogenesis of mesenchymal stem cells in collagen mimetic peptide-mediated microenvironment. Tissue Eng: Part A 14: 1-9.
27. Yang F, Williams CG, Wang DA, et al. 2005. The effect of incorporating RGD adhesive peptide in polyethylene glycol diacrylate hydrogel on osteogenesis of bone marrow stromal cells. Biomaterials 26: 5991-5998.
28. Re'em T, Kaminer-Israeli Y, Ruvinov E, et al. 2012. Chondrogenesis of hMSC in affinity-bound TGF-beta scaffolds. Biomaterials 33: 751-761.
29. Lee KW, Yoon JJ, Lee JH, et al. 2004. Sustained release of vascular endothelial growth factor from calcium-induced alginate hydrogels reinforced by heparin and chitosan. Transplant Proc 36: 2464-2465.
30. Sanchez M, Anitua E, Azofra J, et al. 2007. Comparison of surgically repaired Achilles tendon tears using platelet-rich fibrin matrices. Am J Sports Med 35: 245-251.
31. Fortier LA, Potter HG, Rickey EJ, et al. 2010. Concentrated bone marrow aspirate improves full-thickness cartilage repair compared with microfracture in the equine model. J Bone Joint Surg Am 92: 1927-1937.
32. A Gobbi GK, Scotti C, Mahajan V, et al. 2011. One-step cartilage repair with bone marrow aspirate concentrated cells and collagen matrix in full-thickness knee cartilage lesions: results at 2-year follow-up. Cartilage 2: 14.
33. Mishra A, Pavelko T,. 2006. Treatment of chronic elbow tendinosis with buffered platelet-rich plasma. Am J Sports Med 34: 1774-1778.
34. You TM, Choi BH, Zhu SJ, et al. 2007. Platelet-enriched fibrin glue and platelet-rich plasma in the repair of bone defects adjacent to titanium dental implants. Int J Oral Maxillofac Implants 22: 417-422.
35. Bhargava MM, Attia ET, Murrell GA, et al. 1999. The effect of cytokines on the proliferation and migration of bovine meniscal cells. Am J Sports Med 27: 636-643.
36. Ozaki Y, Nishimura M, Sekiya K, et al. 2007. Comprehensive analysis of chemotactic factors for bone marrow mesenchymal stem cells. Stem Cells Dev 16: 119-129.
37. Doucet C, Ernou I, Zhang Y, et al. 2005. Platelet lysates promote mesenchymal stem cell expansion: a safety substitute for animal serum in cell-based therapy applications. J Cell Physiol 205: 228-236.
38. Zhao G, Yin S, Liu G, et al. 2009. In vitro engineering of fibrocartilage using CDMP1 induced dermal fibroblasts and polyglycolide. Biomaterials 30: 3241-3250.
39. Collier S, Ghosh P,. 1995. Effects of transforming growth factor beta on proteoglycan synthesis by cell and explant cultures derived from the knee joint meniscus. Osteoarthritis Cartilage 3: 127-138.
40. Chow TW, Mcintire LV, Peterson DM,. 1983. Importance of plasma fibronectin in determining PFP and PRP clot mechanical properties. Thromb Res 29: 243-248.
41. Ruoslahti E, Pierschbacher MD,. 1987. New perspectives in cell adhesion: RGD and integrins. Science 238: 491-497.
42. Keogh MB, FJ OB, Daly JS,. 2010. A novel collagen scaffold supports human osteogenesis-applications for bone tissue engineering. Cell Tissue Res 340: 169-177.
43. Nevo Z, Dorfman A,. 1972. Stimulation of chondromucoprotein synthesis in chondrocytes by extracellular chondromucoprotein. Proc Natl Acad Sci USA 69: 2069-2072.
44. Neuss S, Schneider RK, Tietze L, et al. 2010. Secretion of fibrinolytic enzymes facilitates human mesenchymal stem cell invasion into fibrin clots. Cells Tissues Organs 191: 36-46.
45. Wang DA, Varghese S, Sharma B, et al. 2007. Multifunctional chondroitin sulphate for cartilage tissue-biomaterial integration. Nat Mater 6: 385-392.
46. Sim R, Liang TS, Tay BK,. 1993. Autologous marrow injection in the treatment of delayed and non-union in long bones. Singapore Med J 34: 412-417.
47. Jager M, Herten M, Fochtmann U, et al. 2011. Bridging the gap: bone marrow aspiration concentrate reduces autologous bone grafting in osseous defects. J Orthop Res 29: 173-180.
48. Catelas I, Sese N, Wu BM, et al. 2006. Human mesenchymal stem cell proliferation and osteogenic differentiation in fibrin gels in vitro. Tissue Eng 12: 2385-2396.
49. Linde A, Jontell M, Lundgren T, et al. 1983. Noncollagenous proteins of rat compact bone. J Biol Chem 258: 1698-1705.
50. Fischer H, Scherz J, Szabo S, et al. 2011. DNase 2 is the main DNA-degrading enzyme of the stratum corneum. PLoS ONE 6: e17581.