Effects of the activated mitogen-activated protein kinase pathway via the c-ros receptor tyrosine kinase on the T47D breast cancer cell line following alcohol exposure

Oncology Reports

Volumn 29, Issue 3, 2013, Pages 868-874

  Lee, Hyung Tae ^a   Kim, Se Kye ^a   Choi, Mi Ran ^a   Park, Ji Hyun ^a   Jung, Kyoung Hwa ^a   Chai, Young Gyu ^a  

^a Hanyang University   (South Korea)

Author keywords

Alcohol; Breast cancer; Histone phosphorylation; Mitogen activated protein kinase pathway; Receptor tyrosine kinase

Indexed keywords

ALCOHOL; C ROS RECEPTOR TYROSINE KINASE; HISTONE H3; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN AND STRESS ACTIVATED PROTEIN KINASE 1; PROTEIN 14 3 3; PROTEIN KINASE; PROTEIN TYROSINE KINASE; UNCLASSIFIED DRUG;

ARTICLE; AUTOPHOSPHORYLATION; CANCER CELL; CELL NUCLEUS; CELL PROLIFERATION; CONTROLLED STUDY; GENE EXPRESSION; GENE EXPRESSION REGULATION; GROWTH REGULATION; HISTONE PHOSPHORYLATION; HUMAN; HUMAN CELL; IMMEDIATE EARLY GENE; NUCLEOTIDE SEQUENCE; ONCOGENE C FOS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEOMICS;

ALCOHOL DRINKING; BREAST NEOPLASMS; BUTADIENES; CELL LINE, TUMOR; ETHANOL; FEMALE; GENE EXPRESSION; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMMEDIATE-EARLY PROTEINS; MAP KINASE KINASE 1; MAP KINASE KINASE 2; MAP KINASE SIGNALING SYSTEM; NITRILES; PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS; UP-REGULATION;

EID: 84872776849     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2012.2209     Document Type: Article

References (39)

1. Boffetta P and Hashibe M: Alcohol and cancer. Lancet Oncol 7: 149-156, 2006. (Pubitemid 43159501)
2. Seitz HK and Stickel F: Molecular mechanisms of alcoholmediated carcinogenesis. Nat Rev Cancer 7: 599-612, 2007.
3. Boffetta P, Hashibe M, La Vecchia C, Zatonski W and Rehm J: The burden of cancer attributable to alcohol drinking. Int J Cancer 119: 884-887, 2006. (Pubitemid 44051453)
4. Aroor AR and Shukla SD: MAP kinase signaling in diverse effects of ethanol. Life Sci 74: 2339-2364, 2004. (Pubitemid 38293254)
5. Santen RJ, Song RX, McPherson R, Kumar R, Adam L, Jeng MH and Yue W: The role of mitogen-activated protein (MAP) kinase in breast cancer. J Steroid Biochem Mol Biol 80: 239-256, 2002. (Pubitemid 34233743)
6. Mueller H, Flury N, Eppenberger-Castori S, Kueng W, David F and Eppenberger U: Potential prognostic value of mitogen-activated protein kinase activity for disease-free survival of primary breast cancer patients. Int J Cancer 89: 384-388, 2000. (Pubitemid 30620293)
7. Izevbigie EB, Ekunwe SI, Jordan J and Howard CB: Ethanol modulates the growth of human breast cancer cells in vitro. Exp Biol Med (Maywood) 227: 260-265, 2002.
8. Park PH, Lim RW and Shukla SD: Involvement of histone acetyltransferase (HAT) in ethanol-induced acetylation of histone H3 in hepatocytes: potential mechanism for gene expression. Am J Physiol Gastrointest Liver Physiol 289: G1124-G1136, 2005. (Pubitemid 41740619)
9. James TT, Aroor AR, Lim RW and Shukla SD: Histone H3 phosphorylation (Ser10, Ser28) and phosphoacetylation (K9S10) are differentially associated with gene expression in liver of rats treated in vivo with acute ethanol. J Pharmacol Exp Ther 340: 237-247, 2012.
10. Chi P, Allis CD and Wang GG: Covalent histone modifications - miswritten, misinterpreted and mis-erased in human cancers. Nat Rev Cancer 10: 457-469, 2010.
11. Jenuwein T and Allis CD: Translating the histone code. Science 293: 1074-1080, 2001. (Pubitemid 32758077)
12. Kouzarides T: Chromatin modifications and their function. Cell 128: 693-705, 2007. (Pubitemid 46273577)
13. Baek SH: When signaling kinases meet histones and histone modifiers in the nucleus. Mol Cell 42: 274-284, 2011.
14. Zhong S, Jansen C, She QB, Goto H, Inagaki M, Bode AM, Ma WY and Dong Z: Ultraviolet B-induced phosphorylation of histone H3 at serine 28 is mediated by MSK1. J Biol Chem 276: 33213-33219, 2001.
15. He Z, Cho YY, Ma WY, Choi HS, Bode AM and Dong Z: Regulation of ultraviolet B-induced phosphorylation of histone H3 at serine 10 by Fyn kinase. J Biol Chem 280: 2446-2454, 2005. (Pubitemid 40189344)
16. Lee YJ and Shukla SD: Histone H3 phosphorylation at serine 10 and serine 28 is mediated by p38 MAPK in rat hepatocytes exposed to ethanol and acetaldehyde. Eur J Pharmacol 573: 29-38, 2007. (Pubitemid 47470061)
17. Soloaga A, Thomson S, Wiggin GR, Rampersaud N, Dyson MH, Hazzalin CA, Mahadevan LC and Arthur JS: MSK2 and MSK1 mediate the mitogen- and stress-induced phosphorylation of histone H3 and HMG-14. EMBO J 22: 2788-2797, 2003. (Pubitemid 36712374)
18. Reul JM and Chandramohan Y: Epigenetic mechanisms in stress-related memory formation. Psychoneuroendocrinology 32 (Suppl 1): S21-S25, 2007. (Pubitemid 47211635)
19. Clayton AL, Rose S, Barratt MJ and Mahadevan LC: Phosphoacetylation of histone H3 on c-fos- and c-jun-associated nucleosomes upon gene activation. EMBO J 19: 3714-3726, 2000. (Pubitemid 30462129)
20. Hazzalin CA and Mahadevan LC: MAPK-regulated transcription: a continuously variable gene switch? Nat Rev Mol Cell Biol 3: 30-40, 2002. (Pubitemid 135709916)
21. Strelkov IS and Davie JR: Ser-10 phosphorylation of histone H3 and immediate early gene expression in oncogene-transformed mouse fibroblasts. Cancer Res 62: 75-78, 2002. (Pubitemid 34073989)
22. Chadee DN, Hendzel MJ, Tylipski CP, Allis CD, Bazett-Jones DP, Wright JA and Davie JR: Increased Ser-10 phosphorylation of histone H3 in mitogen-stimulated and oncogene-transformed mouse fibroblasts. J Biol Chem 274: 24914-24920, 1999.
23. Choi MR, Jung KH, Park JH, Das ND, Chung MK, Choi IG, Lee BC, Park KS and Chai YG: Ethanol-induced small heat shock protein genes in the differentiation of mouse embryonic neural stem cells. Arch Toxicol 85: 293-304, 2011.
24. Jung KH, Das ND, Park JH, Lee HT, Choi MR, Chung MK, Park KS, Jung MH, Lee BC, Choi IG and Chai YG: Effects of acute ethanol treatment on NCCIT cells and NCCIT cell-derived embryoid bodies (EBs). Toxicol In Vitro 24: 1696-1704, 2010.
25. Shevchenko A, Wilm M, Vorm O and Mann M: Mass spectrometric sequencing of proteins silver-stained polyacrylamide gels. Anal Chem 68: 850-858, 1996.
26. Baik SY, Jung KH, Choi MR, Yang BH, Kim SH, Lee JS, Oh DY, Choi IG, Chung H and Chai YG: Fluoxetine-induced up-regulation of 14-3-3zeta and tryptophan hydroxylase levels in RBL-2H3 cells. Neurosci Lett 374: 53-57, 2005. (Pubitemid 41556547)
27. Choe MK, Hong CP, Park J, Seo SH and Roh TY: Functional elements demarcated by histone modifications in breast cancer cells. Biochem Biophys Res Commun 418: 475-482, 2012.
28. Macdonald N, Welburn J P, Noble ME, Nguyen A, Yaffe MB, Clynes D, Moggs JG, Orphanides G, Thomson S, Edmunds JW, Clayton AL, Endicott JA and Mahadevan LC: Molecular basis for the recognition of phosphorylated and phosphoacetylated histone h3 by 14-3-3. Mol Cell 20: 199-211, 2005. (Pubitemid 41484166)
29. Drobic B, Perez-Cadahia B, Yu J, Kung SK and Davie JR: Promoter chromatin remodeling of immediate-early genes is mediated through H3 phosphorylation at either serine 28 or 10 by the MSK1 multi-protein complex. Nucleic Acids Res 38: 3196-3208, 2010.
30. Acquaviva J, Wong R and Charest A: The multifaceted roles of the receptor tyrosine kinase ROS in development and cancer. Biochim Biophys Acta 1795: 37-52, 2009.
31. Hubbard SR and Miller WT: Receptor tyrosine kinases: mechanisms of activation and signaling. Curr Opin Cell Biol 19: 117-123, 2007. (Pubitemid 46386407)
32. Aroor AR, James TT, Jackson DE and Shukla SD: Differential changes in MAP kinases, histone modifications, and liver injury in rats acutely treated with ethanol. Alcohol Clin Exp Res 34: 1543-1551, 2010.
33. Hong SK, Yoon S, Moelling C, Arthan D and Park JI: Non-catalytic function of ERK1/2 can promote Raf/MEK/ERK-mediated growth arrest signaling. J Biol Chem 284: 33006-33018, 2009.
34. Chung J, Liu C, Smith DE, Seitz HK, Russell RM and Wang XD: Restoration of retinoic acid concentration suppresses ethanol-enhanced c-Jun expression and hepatocyte proliferation in rat liver. Carcinogenesis 22: 1213-1219, 2001. (Pubitemid 32737338)
35. Wang XD: Alcohol, vitamin A, and cancer. Alcohol 35: 251-258, 2005.
36. Simoni D and Tolomeo M: Retinoids, apoptosis and cancer. Curr Pharm Des 7: 1823-1837, 2001. (Pubitemid 32998338)
37. Hennig M, Yip-Schneider MT, Klein P, Wentz S, Matos JM, Doyle C, Choi J, Wu H, O'Mara A, Menze A, Noble S, McKillop IH and Schmidt CM: Ethanol-TGFalpha-MEK signaling promotes growth of human hepatocellular carcinoma. J Surg Res 154: 187-195, 2009.
38. Ku BM, Lee YK, Jeong JY, Mun J, Han JY, Roh GS, Kim HJ, Cho GJ, Choi WS, Yi GS and Kang SS: Ethanol-induced oxidative stress is mediated by p38 MAPK pathway in mouse hippocampal cells. Neurosci Lett 419: 64-67, 2007. (Pubitemid 46694105)
39. Aitken A: 14-3-3 and its possible role in co-ordinating multiple signalling pathways. Trends Cell Biol 6: 341-347, 1996. (Pubitemid 26283439)