-
1
-
-
0038179723
-
Cost of migration: Invasion of malignant gliomas and implications for treatment
-
DOI 10.1200/JCO.2003.05.063
-
Giese A, Bjerkvig R, Berens ME and Westphal M: Cost of migration: invasion of malignant gliomas and implications for treatment. J Clin Oncol 21: 1624-1636, 2003. (Pubitemid 46594118)
-
(2003)
Journal of Clinical Oncology
, vol.21
, Issue.8
, pp. 1624-1636
-
-
Giese, A.1
Bjerkvig, R.2
Berens, M.E.3
Westphal, M.4
-
2
-
-
34248136479
-
Inhibition of both focal adhesion kinase and insulin-like growth factor-I receptor kinase suppresses glioma proliferation in vitro and in vivo
-
DOI 10.1158/1535-7163.MCT-06-0476
-
Liu TJ, LaFortune T, Honda T, Ohmori O, Hatakeyama S, Meye T, Jackson D, de Groot J and Yung WK: Inhibition of both focal adhesion kinase and insulin-like growth factor-I receptor kinase suppresses glioma proliferation in vitro and in vivo. Mol Cancer Ther 6: 1357-1367, 2007. (Pubitemid 46711999)
-
(2007)
Molecular Cancer Therapeutics
, vol.6
, Issue.4
, pp. 1357-1367
-
-
Liu, T.-J.1
LaFortune, T.2
Honda, T.3
Ohmori, O.4
Hatakeyama, S.5
Meyer, T.6
Jackson, D.7
De Groot, J.8
Yung, W.K.A.9
-
3
-
-
0025790916
-
Genes for epidermal growth factor receptor, transforming growth factor alpha, and epidermal growth factor and their expression in human gliomas in vivo
-
Ekstrand AJ, James CD, Cavenee WK, Seliger B, Pettersson RF and Collins VP: Genes for epidermal growth factor receptor, transforming growth factor alpha, and epidermal growth factor and their expression in human gliomas in vivo. Cancer Res 51: 2164-2172, 1991.
-
(1991)
Cancer Res
, vol.51
, pp. 2164-2172
-
-
Ekstrand, A.J.1
James, C.D.2
Cavenee, W.K.3
Seliger, B.4
Pettersson, R.F.5
Collins, V.P.6
-
4
-
-
33947681747
-
The epidermal growth factor receptor in malignant gliomas: Pathogenesis and therapeutic implications
-
DOI 10.1517/14728222.11.4.463
-
Nakamura JL: The epidermal growth factor receptor in malignant gliomas: pathogenesis and therapeutic implications. Expert Opin Ther Targets 11: 463-472, 2007. (Pubitemid 46487595)
-
(2007)
Expert Opinion on Therapeutic Targets
, vol.11
, Issue.4
, pp. 463-472
-
-
Nakamura, J.L.1
-
5
-
-
27744606737
-
Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors
-
DOI 10.1056/NEJMoa051918
-
Mellinghoff IK, Wang MY, Vivanco I, Haas-Kogan DA, Zhu S, Dia EQ, Lu KV, Yoshimoto K, Huang JH, Chute DJ, Riggs BL, Horvath S, Liau LM, Cavenee WK, Rao PN, Beroukhim R, Peck TC, Lee JC, Sellers WR, Stokoe D, Prados M, Cloughesy TF, Sawyers CL and Mischel PS: Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors. N Engl J Med 353: 2012-2024, 2005. (Pubitemid 41609094)
-
(2005)
New England Journal of Medicine
, vol.353
, Issue.19
, pp. 2012-2024
-
-
Mellinghoff, I.K.1
Wang, M.Y.2
Vivanco, I.3
Haas-Kogan, D.A.4
Zhu, S.5
Dia, E.Q.6
Lu, K.V.7
Yoshimoto, K.8
Huang, J.H.Y.9
Chute, D.J.10
Riggs, B.L.11
Horvath, S.12
Liau, L.M.13
Cavenee, W.K.14
Nagesh Rao, P.15
Beroukhim, R.16
Peck, T.C.17
Lee, J.C.18
Sellers, W.R.19
Stokoe, D.20
Prados, M.21
Cloughesy, T.F.22
Sawyers, C.L.23
Mischel, P.S.24
more..
-
6
-
-
0027179703
-
Eps8, a substrate for the epidermal growth factor receptor kinase, enhances EGF-dependent mitogenic signals
-
Fazioli F, Minichiello L, Matoska V, Castagnino P, Miki T, Wong WT and Di Fiore PP: Eps8, a substrate for the epidermal growth factor receptor kinase, enhances EGF-dependent mitogenic signals. EMBO J 12: 3799-3808, 1993. (Pubitemid 23282756)
-
(1993)
EMBO Journal
, vol.12
, Issue.10
, pp. 3799-3808
-
-
Fazioli, F.1
Minichiello, L.2
Matoska, V.3
Castagnino, P.4
Miki, T.5
Wong, W.T.6
Di Fiore, P.P.7
-
7
-
-
0033028804
-
Enhancement of tyrosyl phosphorylation and protein expression of eps8 by v-Src
-
Maa MC, Lai JR, Lin RW and Leu TH: Enhancement of tyrosyl phosphorylation and protein expression of eps8 by v-Src. Biochim Biophys Acta 1450: 341-351, 1999.
-
(1999)
Biochim Biophys Acta
, vol.1450
, pp. 341-351
-
-
Maa, M.C.1
Lai, J.R.2
Lin, R.W.3
Leu, T.H.4
-
8
-
-
0028922935
-
Direct binding of eps8 to the juxtamembrane domain of EGFR is phosphotyrosine- and SH2-independent
-
Castagnino P, Biesova Z, Wong WT, Fazioli F, Gill GN and Di Fiore PP: Direct binding of eps8 to the juxtamembrane domain of EGFR is phosphotyrosine- and SH2-independent. Oncogene 10: 723-729, 1995.
-
(1995)
Oncogene
, vol.10
, pp. 723-729
-
-
Castagnino, P.1
Biesova, Z.2
Wong, W.T.3
Fazioli, F.4
Gill, G.N.5
Di Fiore, P.P.6
-
9
-
-
0029054142
-
Constitutive phosphorylation of eps8 in tumor cell lines: Relevance to malignant transformation
-
Matoskova B, Wong WT, Salcini AE, Pelicci PG and Di Fiore PP: Constitutive phosphorylation of eps8 in tumor cell lines: relevance to malignant transformation. Mol Cell Biol 15: 3805-3812, 1995.
-
(1995)
Mol Cell Biol
, vol.15
, pp. 3805-3812
-
-
Matoskova, B.1
Wong, W.T.2
Salcini, A.E.3
Pelicci, P.G.4
Di Fiore, P.P.5
-
10
-
-
0033575885
-
Eps8 and E3B1 transduce signals from Ras to Rac
-
Scita G, Nordstrom J, Carbone R, Tenca P, Giardina G, Gutkind S, Bjarnegard M, Betsholtz C and Di Fiore PP: Eps8 and E3B1 transduce signals from Ras to Rac. Nature 401: 290-293, 1999.
-
(1999)
Nature
, vol.401
, pp. 290-293
-
-
Scita, G.1
Nordstrom, J.2
Carbone, R.3
Tenca, P.4
Giardina, G.5
Gutkind, S.6
Bjarnegard, M.7
Betsholtz, C.8
Di Fiore, P.P.9
-
11
-
-
0035802118
-
An effector region in Eps8 is responsible for the activation of the Rac-specific GEF activity of Sos-1 and for the proper localization of the Rac-based actin-polymerizing machine
-
DOI 10.1083/jcb.200103146
-
Scita G, Tenca P, Areces LB, Tocchetti A, Frittoli E, Giardina G, Ponzanelli I, Sini P, Innocenti M and Di Fiore PP: An effector region in Eps8 is responsible for the activation of the Rac-specific GEF activity of Sos-1 and for the proper localization of the Rac-based actin-polymerizing machine. J Cell Biol 154: 1031-1044, 2001. (Pubitemid 34286182)
-
(2001)
Journal of Cell Biology
, vol.154
, Issue.5
, pp. 1031-1044
-
-
Scita, G.1
Tenca, P.2
Areces, L.B.3
Tocchetti, A.4
Frittoli, E.5
Giardina, G.6
Ponzanelli, I.7
Sini, P.8
Innocenti, M.9
Di Fiore, P.P.10
-
12
-
-
78649952069
-
Integrity of SOS1/EPS8/ABI1 tri-complex determines ovarian cancer metastasis
-
Chen H, Wu X, Pan ZK and Huang S: Integrity of SOS1/EPS8/ABI1 tri-complex determines ovarian cancer metastasis. Cancer Res 70: 9979-9990, 2010.
-
(2010)
Cancer Res
, vol.70
, pp. 9979-9990
-
-
Chen, H.1
Wu, X.2
Pan, Z.K.3
Huang, S.4
-
13
-
-
77953957570
-
EPS8 upregulates FOXM1 expression, enhancing cell growth and motility
-
Wang H, Teh MT, Ji Y, Patel V, Firouzabadian S, Patel AA, Gutkind JS and Yeudall WA: EPS8 upregulates FOXM1 expression, enhancing cell growth and motility. Carcinogenesis 31: 1132-1141, 2010.
-
(2010)
Carcinogenesis
, vol.31
, pp. 1132-1141
-
-
Wang, H.1
Teh, M.T.2
Ji, Y.3
Patel, V.4
Firouzabadian, S.5
Patel, A.A.6
Gutkind, J.S.7
Yeudall, W.A.8
-
14
-
-
49849083350
-
Eps8 decreases chemosensitivity and affects survival of cervical cancer patients
-
Chen YJ, Shen MR, Chen YJ, Maa MC and Leu TH: Eps8 decreases chemosensitivity and affects survival of cervical cancer patients. Mol Cancer Ther 7: 1376-1385, 2008.
-
(2008)
Mol Cancer Ther
, vol.7
, pp. 1376-1385
-
-
Chen, Y.J.1
Shen, M.R.2
Chen, Y.J.3
Maa, M.C.4
Leu, T.H.5
-
15
-
-
34547104027
-
Eps8 facilitates cellular growth and motility of colon cancer cells by increasing the expression and activity of focal adhesion kinase
-
Maa MC, Lee JC, Chen YJ, Chen YJ, Lee YC, Wang ST, Huang CC, Chow NH and Leu TH: Eps8 facilitates cellular growth and motility of colon cancer cells by increasing the expression and activity of focal adhesion kinase. J Biol Chem 282: 19399-19409, 2007.
-
(2007)
J Biol Chem
, vol.282
, pp. 19399-19409
-
-
Maa, M.C.1
Lee, J.C.2
Chen, Y.J.3
Chen, Y.J.4
Lee, Y.C.5
Wang, S.T.6
Huang, C.C.7
Chow, N.H.8
Leu, T.H.9
-
16
-
-
58949087569
-
Role for EPS8 in squamous carcinogenesis
-
Wang H, Patel V, Miyazaki H, Gutkind JS and Yeudall WA: Role for EPS8 in squamous carcinogenesis. Carcinogenesis 30: 165-174, 2009.
-
(2009)
Carcinogenesis
, vol.30
, pp. 165-174
-
-
Wang, H.1
Patel, V.2
Miyazaki, H.3
Gutkind, J.S.4
Yeudall, W.A.5
-
17
-
-
67149147296
-
Structure of human lanthionine synthetase C-like protein 1 and its interaction with Eps8 and glutathione
-
Zhang W, Wang L, Liu Y, Xu J, Zhu G, Cang H, Li X, Bartlam M, Hensley K, Li G, Rao Z and Zhang XC: Structure of human lanthionine synthetase C-like protein 1 and its interaction with Eps8 and glutathione. Genes Dev 23: 1387-1392, 2009.
-
(2009)
Genes Dev
, vol.23
, pp. 1387-1392
-
-
Zhang, W.1
Wang, L.2
Liu, Y.3
Xu, J.4
Zhu, G.5
Cang, H.6
Li, X.7
Bartlam, M.8
Hensley, K.9
Li, G.10
Rao, Z.11
Zhang, X.C.12
-
18
-
-
34547937489
-
Eps8 is increased in pancreatic cancer and required for dynamic actin-based cell protrusions and intercellular cytoskeletal organization
-
DOI 10.1016/j.canlet.2007.04.008, PII S0304383507001966
-
Welsch T, Endlich K, Giese T, Buchler MW and Schmidt J: Eps8 is increased in pancreatic cancer and required for dynamic actin-based cell protrusions and intercellular cytoskeletal organization. Cancer Lett 255: 205-218, 2007. (Pubitemid 47268639)
-
(2007)
Cancer Letters
, vol.255
, Issue.2
, pp. 205-218
-
-
Welsch, T.1
Endlich, K.2
Giese, T.3
Buchler, M.W.4
Schmidt, J.5
-
19
-
-
71349087432
-
Mithramycin inhibits human epithelial carcinoma cell proliferation and migration involving downregulation of Eps8 expression
-
Yang TP, Chiou HL, Maa MC and Wang CJ: Mithramycin inhibits human epithelial carcinoma cell proliferation and migration involving downregulation of Eps8 expression. Chem Biol Interact 183: 181-186, 2010.
-
(2010)
Chem Biol Interact
, vol.183
, pp. 181-186
-
-
Yang, T.P.1
Chiou, H.L.2
Maa, M.C.3
Wang, C.J.4
-
20
-
-
84861886952
-
Subcellular location of EPS8 by its expression and preparation of antiserum
-
Luo C, Ding XF, Sun YB and Han M: Subcellular location of EPS8 by its expression and preparation of antiserum. J Nat Sci Hunan Normal University 31: 100-104, 2008.
-
(2008)
J Nat Sci Hunan Normal University
, vol.31
, pp. 100-104
-
-
Luo, C.1
Ding, X.F.2
Sun, Y.B.3
Han, M.4
-
21
-
-
0035035911
-
Localization of GFP-tagged concentrative nucleoside transporters in a renal polarized epithelial cell line
-
Mangravite LM, Lipschutz JH, Mostov KE and Giacomini KM: Localization of GFP-tagged concentrative nucleoside transporters in a renal polarized epithelial cell line. Am J Physiol Renal Physiol 280: F879-F885, 2001.
-
(2001)
Am J Physiol Renal Physiol
, vol.280
-
-
Mangravite, L.M.1
Lipschutz, J.H.2
Mostov, K.E.3
Giacomini, K.M.4
-
22
-
-
0034595687
-
Dynamics of NF αB and IαBα studied with green fluorescent protein (GFP) fusion proteins: Investigation of GFP-p65 binding to DNA by fluorescence resonance energy transfer
-
DOI 10.1074/jbc.M000291200
-
Schmid JA, Birbach A, Hofer-Warbinek R, Pengg M, Burner U, Furtmuller PG, Binder BR and de Martin R: Dynamics of NF kappa B and Ikappa Balpha studied with green fluorescent protein (GFP) fusion proteins. Investigation of GFP-p65 binding to DNa by fluorescence resonance energy transfer. J Biol Chem 275: 17035-17042, 2000. (Pubitemid 30398945)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.22
, pp. 17035-17042
-
-
Schmid, J.A.1
Birbach, A.2
Hofer-Warbinek, R.3
Pengg, M.4
Burner, U.5
Furtmuller, P.G.6
Binder, B.R.7
De Martin, R.8
-
23
-
-
0036468677
-
Germline transmission and tissue-specific expression of transgenes delivered by lentiviral vectors
-
DOI 10.1126/science.1067081
-
Lois C, Hong EJ, Pease S, Brown EJ and Baltimore D: Germline transmission and tissue-specific expression of transgenes delivered by lentiviral vectors. Science 295: 868-872, 2002. (Pubitemid 34118370)
-
(2002)
Science
, vol.295
, Issue.5556
, pp. 868-872
-
-
Lois, C.1
Hong, E.J.2
Pease, S.3
Brown, E.J.4
Baltimore, D.5
-
24
-
-
0347360339
-
The eps8 Family of Proteins Links Growth Factor Stimulation to Actin Reorganization Generating Functional Redundancy in the Ras/Rac Pathway
-
DOI 10.1091/mbc.E03-06-0427
-
Offenhauser N, Borgonovo A, Disanza A, Romano P, Ponzanelli I, Iannolo G, Di Fiore PP and Scita G: The eps8 family of proteins links growth factor stimulation to actin reorganization generating functional redundancy in the Ras/Rac pathway. Mol Biol Cell 15: 91-98, 2004. (Pubitemid 38044946)
-
(2004)
Molecular Biology of the Cell
, vol.15
, Issue.1
, pp. 91-98
-
-
Offenhauser, N.1
Borgonovo, A.2
Disanza, A.3
Romano, P.4
Ponzanelli, I.5
Iannolo, G.6
Di Fiore, P.P.7
Scita, G.8
-
25
-
-
67649935286
-
Eps8 regulates axonal filopodia in hippocampal neurons in response to brain-derived neurotrophic factor (BDNF)
-
Menna E, Disanza A, Cagnoli C, Schenk U, Gelsomino G, Frittoli E, Hertzog M, Offenhauser N, Sawallisch C, Kreienkamp HJ, Gertler FB, Di Fiore PP, Scita G and Matteoli M: Eps8 regulates axonal filopodia in hippocampal neurons in response to brain-derived neurotrophic factor (BDNF). PLoS Biol 7: e1000138, 2009.
-
(2009)
PLoS Biol
, vol.7
-
-
Menna, E.1
Disanza, A.2
Cagnoli, C.3
Schenk, U.4
Gelsomino, G.5
Frittoli, E.6
Hertzog, M.7
Offenhauser, N.8
Sawallisch, C.9
Kreienkamp, H.J.10
Gertler, F.B.11
Di Fiore, P.P.12
Scita, G.13
Matteoli, M.14
-
26
-
-
0036727502
-
Activation and role of MAP kinase-dependent pathways in retinal pigment epithelial cells: ERK and RPE cell proliferation
-
Hecquet C, Lefevre G, Valtink M, Engelmann K and Mascarelli F: Activation and role of MAP kinase-dependent pathways in retinal pigment epithelial cells: ERK and RPE cell proliferation. Invest Ophthalmol Vis Sci 43: 3091-3098, 2002. (Pubitemid 34977064)
-
(2002)
Investigative Ophthalmology and Visual Science
, vol.43
, Issue.9
, pp. 3091-3098
-
-
Hecquet, C.1
Lefevre, G.2
Valtink, M.3
Engelmann, K.4
Mascarelli, F.5
-
27
-
-
79960039308
-
The ERK cascade: Distinct functions within various subcellular organelles
-
Wortzel I and Seger R: The ERK cascade: distinct functions within various subcellular organelles. Genes Cancer 2: 195-209, 2011.
-
(2011)
Genes Cancer
, vol.2
, pp. 195-209
-
-
Wortzel, I.1
Seger, R.2
-
28
-
-
0035008166
-
Wingless-type frizzled protein receptor signaling and its putative role in human colon cancer
-
DOI 10.1002/mc.1039
-
Uthoff SM, Eichenberger MR, McAuliffe TL, Hamilton CJ and Galandiuk S: Wingless-type frizzled protein receptor signaling and its putative role in human colon cancer. Mol Carcinog 31: 56-62, 2001. (Pubitemid 32520668)
-
(2001)
Molecular Carcinogenesis
, vol.31
, Issue.1
, pp. 56-62
-
-
Uthoff, S.M.S.1
Eichenberger, M.R.2
McAuliffe, T.L.3
Hamilton, C.J.4
Galandiuk, S.5
-
29
-
-
0033777043
-
Catenins, Wnt signaling and cancer
-
Barker N and Clevers H: Catenins, Wnt signaling and cancer. Bioessays 22: 961-965, 2000.
-
(2000)
Bioessays
, vol.22
, pp. 961-965
-
-
Barker, N.1
Clevers, H.2
-
30
-
-
0033895709
-
Wnt signaling and cancer
-
Polakis P: Wnt signaling and cancer. Genes Dev 14: 1837-1851, 2000. (Pubitemid 30639518)
-
(2000)
Genes and Development
, vol.14
, Issue.15
, pp. 1837-1851
-
-
Polakis, P.1
-
31
-
-
85028115908
-
β-Catenin overexpression in malignant glioma and its role in proliferation and apoptosis in glioblastoma cells
-
Liu X WL, Zhao S, Ji X, Luo Y and Ling F: β-Catenin overexpression in malignant glioma and its role in proliferation and apoptosis in glioblastoma cells. Med Oncol 28: 608-614, 2011.
-
(2011)
Med Oncol
, vol.28
, pp. 608-614
-
-
Liu X, W.L.1
Zhao, S.2
Ji, X.3
Luo, Y.4
Ling, F.5
-
32
-
-
79959951151
-
High β-catenin/Tcf-4 activity confers glioma progression via direct regulation of AKT2 gene expression
-
Zhang J HK, Shi Z, Zou J, Wang Y, Jia Z, Zhang A, Han L, Yue X, Liu N, Jiang T, You Y, Pu P and Kang C: High β-catenin/Tcf-4 activity confers glioma progression via direct regulation of AKT2 gene expression. Neuro Oncol 13: 600-609, 2011.
-
(2011)
Neuro Oncol
, vol.13
, pp. 600-609
-
-
Zhang, J.H.K.1
Shi, Z.2
Zou, J.3
Wang, Y.4
Jia, Z.5
Zhang, A.6
Han, L.7
Yue, X.8
Liu, N.9
Jiang, T.10
You, Y.11
Pu, P.12
Kang, C.13
-
33
-
-
66449089619
-
Epidermal growth factor receptor pathway substrate 8 is overexpressed in human pituitary tumors: Role in proliferation and survival
-
Xu M, Shorts-Cary L, Knox AJ, Kleinsmidt-DeMasters B, Lillehei K and Wierman ME: Epidermal growth factor receptor pathway substrate 8 is overexpressed in human pituitary tumors: role in proliferation and survival. Endocrinology 150: 2064-2071, 2009.
-
(2009)
Endocrinology
, vol.150
, pp. 2064-2071
-
-
Xu, M.1
Shorts-Cary, L.2
Knox, A.J.3
Kleinsmidt-DeMasters, B.4
Lillehei, K.5
Wierman, M.E.6
-
35
-
-
77949937466
-
Interferon-gamma regulates intestinal epithelial homeostasis through converging beta-catenin signaling pathways
-
Nava P, Koch S, Laukoetter MG, Lee WY, Kolegraff K, Capaldo CT, Beeman N, Addis C, Gerner-Smidt K, Neumaier I, Skerra A, Li L, Parkos CA and Nusrat A: Interferon-gamma regulates intestinal epithelial homeostasis through converging beta-catenin signaling pathways. Immunity 32: 392-402, 2010.
-
(2010)
Immunity
, vol.32
, pp. 392-402
-
-
Nava, P.1
Koch, S.2
Laukoetter, M.G.3
Lee, W.Y.4
Kolegraff, K.5
Capaldo, C.T.6
Beeman, N.7
Addis, C.8
Gerner-Smidt, K.9
Neumaier, I.10
Skerra, A.11
Li, L.12
Parkos, C.A.13
Nusrat, A.14
|