Synthesis and biological evaluation of some novel resveratrol amide derivatives as potential anti-tumor agents

European Journal of Medicinal Chemistry

Volumn 62, Issue , 2013, Pages 222-231

  Yao, Ri Sheng ^a   Lu, Xiao Qin ^a   Guan, Qiu Xiang ^a   Zheng, Lei ^a   Lu, Xiang ^b   Ruan, Ban Feng ^a  

^a HEFEI UNIVERSITY OF TECHNOLOGY   (China)

^b NANJING UNIVERSITY   (China)

Author keywords

Anti tumor; COX 2 inhibitor; Molecular docking; Resveratrol derivatives

Indexed keywords

3 (2,4 DIMETHOXY 6 [ 4 METHOXYSTYRYL)PHENYL) 1 (3,5 DIMETHYLPIPERIDIN 1 YL]PROP 2 EN 1 ONE; AMIDE; ANTINEOPLASTIC AGENT; CYCLOOXYGENASE 2; N (3 CHLOROPROPYL) 3 [2,4 DIMETHOXY 6 ( 4METHOXYSTYRYL)PHENYL]ACRYLAMIDE; N BUTYL 3 [2,4 DIMETHOXY 6 ( 4 METHOXYSTYRYL) PHENYL]ACRYLAMIDE; PROSTAGLANDIN E2; UNCLASSIFIED DRUG;

ANTIINFLAMMATORY ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; BIOLOGICAL ACTIVITY; CANCER CELL CULTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IC 50; MACROPHAGE; MASS SPECTROMETRY; MOLECULAR DOCKING; PROTON NUCLEAR MAGNETIC RESONANCE; X RAY CRYSTALLOGRAPHY;

AMIDES; ANIMALS; ANTINEOPLASTIC AGENTS; CELL LINE; CELL PROLIFERATION; CRYSTALLOGRAPHY, X-RAY; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; DINOPROSTONE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; MCF-7 CELLS; MICE; MODELS, MOLECULAR; MOLECULAR STRUCTURE; STILBENES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84872763299     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2012.11.021     Document Type: Article

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