-
1
-
-
84858163506
-
Systemic mastocytosis in adults: 2012 update on diagnosis, risk stratification, and management
-
Pardanani A. Systemic mastocytosis in adults: 2012 update on diagnosis, risk stratification, and management. Am J Hematol 2012;87:401-11.
-
(2012)
Am J Hematol
, vol.87
, pp. 401-411
-
-
Pardanani, A.1
-
3
-
-
67651015586
-
Most common clinical presentations of cutaneous mastocytosis
-
Bulat V, Mihic LL, Situm M, Buljan M, Blajic I, Pusic J. Most common clinical presentations of cutaneous mastocytosis. Acta Clin Croat 2009;48:59-64.
-
(2009)
Acta Clin Croat
, vol.48
, pp. 59-64
-
-
Bulat, V.1
Mihic, L.L.2
Situm, M.3
Buljan, M.4
Blajic, I.5
Pusic, J.6
-
5
-
-
67651120132
-
Systemic mastocytosis in 342 consecutive adults: survival studies and prognostic factors
-
Lim KH, Tefferi A, Lasho TL, Finke C, Patnaik M, Butterfield JH, McClure RF, Li CY, Pardanani A. Systemic mastocytosis in 342 consecutive adults: survival studies and prognostic factors. Blood 2009;113:5727-36.
-
(2009)
Blood
, vol.113
, pp. 5727-5736
-
-
Lim, K.H.1
Tefferi, A.2
Lasho, T.L.3
Finke, C.4
Patnaik, M.5
Butterfield, J.H.6
McClure, R.F.7
Li, C.Y.8
Pardanani, A.9
-
6
-
-
70449706224
-
Prognostically relevant breakdown of 123 patients with systemic mastocytosis associated with other myeloid malignancies
-
Pardanani A, Lim K, Lasho TL, Finke C, McClure RF, Li C, Tefferi A. Prognostically relevant breakdown of 123 patients with systemic mastocytosis associated with other myeloid malignancies. Blood 2009;114:3769-72.
-
(2009)
Blood
, vol.114
, pp. 3769-3772
-
-
Pardanani, A.1
Lim, K.2
Lasho, T.L.3
Finke, C.4
McClure, R.F.5
Li, C.6
Tefferi, A.7
-
7
-
-
0345772088
-
Aggressive systemic mastocytosis and related mast cell disorders: current treatment options and proposed response criteria
-
Valent P, Akin C, Sperr WR, Escribano L, Arock M, Horny HP, Bennett JM, Metcalfe DD. Aggressive systemic mastocytosis and related mast cell disorders: current treatment options and proposed response criteria. Leuk Res 2003;27:635-41.
-
(2003)
Leuk Res
, vol.27
, pp. 635-641
-
-
Valent, P.1
Akin, C.2
Sperr, W.R.3
Escribano, L.4
Arock, M.5
Horny, H.P.6
Bennett, J.M.7
Metcalfe, D.D.8
-
8
-
-
9744246909
-
Signal transduction via the stem cell factor receptor/c-Kit
-
Ronnstrand L. Signal transduction via the stem cell factor receptor/c-Kit. Cell Mol Life Sci 2004;61:2535-48.
-
(2004)
Cell Mol Life Sci
, vol.61
, pp. 2535-2548
-
-
Ronnstrand, L.1
-
10
-
-
0030889905
-
Kit receptor dimerization is driven by bivalent binding of stem cell factor
-
Lemmon MA, Pinchasi D, Zhou M, Lax I, Schlessinger J. Kit receptor dimerization is driven by bivalent binding of stem cell factor. J Biol Chem 1997;272:6311-7.
-
(1997)
J Biol Chem
, vol.272
, pp. 6311-6317
-
-
Lemmon, M.A.1
Pinchasi, D.2
Zhou, M.3
Lax, I.4
Schlessinger, J.5
-
12
-
-
0036493872
-
The c-KIT mutation causing human mastocytosis is resistant to STI571 and other KIT kinase inhibitors; kinases with enzymatic site mutations show different inhibitor sensitivity profiles than wild-type kinases and those with regulatory-type mutations
-
Ma Y, Zeng S, Metcalfe DD, Akin C, Dimitrijevic S, Butterfield JH, McMahon G, Longley BJ. The c-KIT mutation causing human mastocytosis is resistant to STI571 and other KIT kinase inhibitors; kinases with enzymatic site mutations show different inhibitor sensitivity profiles than wild-type kinases and those with regulatory-type mutations. Blood 2002;99:1741-4.
-
(2002)
Blood
, vol.99
, pp. 1741-1744
-
-
Ma, Y.1
Zeng, S.2
Metcalfe, D.D.3
Akin, C.4
Dimitrijevic, S.5
Butterfield, J.H.6
McMahon, G.7
Longley, B.J.8
-
13
-
-
69849098126
-
Mastocytosis: an unusual clonal disorder of bone marrow-derived hematopoietic progenitor cells
-
Horny HP. Mastocytosis: an unusual clonal disorder of bone marrow-derived hematopoietic progenitor cells. Am J Clin Pathol 2009;132:438-47.
-
(2009)
Am J Clin Pathol
, vol.132
, pp. 438-447
-
-
Horny, H.P.1
-
14
-
-
70449520449
-
Myeloproliferative neoplasms: contemporary diagnosis using histology and genetics
-
Tefferi A, Skoda R, Vardiman JW. Myeloproliferative neoplasms: contemporary diagnosis using histology and genetics. Nat Rev Clin Oncol 2009;6:627-37.
-
(2009)
Nat Rev Clin Oncol
, vol.6
, pp. 627-637
-
-
Tefferi, A.1
Skoda, R.2
Vardiman, J.W.3
-
15
-
-
33749368009
-
KIT mutation in mast cells and other bone marrow hematopoietic cell lineages in systemic mast cell disorders: a prospective study of the Spanish Network on Mastocytosis (REMA) in a series of 113 patients
-
Garcia-Montero AC, Jara-Acevedo M, Teodosio C, et al. KIT mutation in mast cells and other bone marrow hematopoietic cell lineages in systemic mast cell disorders: a prospective study of the Spanish Network on Mastocytosis (REMA) in a series of 113 patients. Blood 2006;108:2366-72.
-
(2006)
Blood
, vol.108
, pp. 2366-2372
-
-
Garcia-Montero, A.C.1
Jara-Acevedo, M.2
Teodosio, C.3
-
16
-
-
69349102308
-
Prognosis in adult indolent systemic mastocytosis: a long-term study of the Spanish Network on Mastocytosis in a series of 145 patients
-
Escribano L, Alvarez-Twose I, Sanchez-Munoz L, et al. Prognosis in adult indolent systemic mastocytosis: a long-term study of the Spanish Network on Mastocytosis in a series of 145 patients. J Allergy Clin Immunol 2009;124:514-21.
-
(2009)
J Allergy Clin Immunol
, vol.124
, pp. 514-521
-
-
Escribano, L.1
Alvarez-Twose, I.2
Sanchez-Munoz, L.3
-
17
-
-
34249333084
-
Standards and standardization in mastocytosis: consensus statements on diagnostics, treatment recommendations and response criteria
-
Valent P, Akin C, Escribano L, et al. Standards and standardization in mastocytosis: consensus statements on diagnostics, treatment recommendations and response criteria. Eur J Clin Invest 2007;37:435-53.
-
(2007)
Eur J Clin Invest
, vol.37
, pp. 435-453
-
-
Valent, P.1
Akin, C.2
Escribano, L.3
-
18
-
-
77951066096
-
A critical reappraisal of treatment response criteria in systemic mastocytosis and a proposal for revisions
-
Pardanani A, Tefferi A. A critical reappraisal of treatment response criteria in systemic mastocytosis and a proposal for revisions. Eur J Haematol 2010;84:371-8.
-
(2010)
Eur J Haematol
, vol.84
, pp. 371-378
-
-
Pardanani, A.1
Tefferi, A.2
-
19
-
-
77956280312
-
The classification of systemic mastocytosis should include mast cell leukemia (MCL) and systemic mastocytosis with a clonal hematologic non-mast cell lineage disease (SM-AHNMD)
-
Valent P, Arock M, Akin C, et al. The classification of systemic mastocytosis should include mast cell leukemia (MCL) and systemic mastocytosis with a clonal hematologic non-mast cell lineage disease (SM-AHNMD). Blood 2010;116:850-1.
-
(2010)
Blood
, vol.116
, pp. 850-851
-
-
Valent, P.1
Arock, M.2
Akin, C.3
-
20
-
-
73349111582
-
Cytoreductive therapy in 108 adults with systemic mastocytosis: outcome analysis and response prediction during treatment with interferon-alpha, hydroxyurea, imatinib mesylate or 2-chlorodeoxyadenosine
-
Lim KH, Pardanani A, Butterfield JH, Li CY, Tefferi A. Cytoreductive therapy in 108 adults with systemic mastocytosis: outcome analysis and response prediction during treatment with interferon-alpha, hydroxyurea, imatinib mesylate or 2-chlorodeoxyadenosine. Am J Hematol 2009;84:790-4.
-
(2009)
Am J Hematol
, vol.84
, pp. 790-794
-
-
Lim, K.H.1
Pardanani, A.2
Butterfield, J.H.3
Li, C.Y.4
Tefferi, A.5
-
21
-
-
0034254249
-
Inhibition of c-kit receptor tyrosine kinase activity by STI 571, a selective tyrosine kinase inhibitor
-
Heinrich MC, Griffith DJ, Druker BJ, Wait CL, Ott KA, Zigler AJ. Inhibition of c-kit receptor tyrosine kinase activity by STI 571, a selective tyrosine kinase inhibitor. Blood 2000;96:925-32.
-
(2000)
Blood
, vol.96
, pp. 925-932
-
-
Heinrich, M.C.1
Griffith, D.J.2
Druker, B.J.3
Wait, C.L.4
Ott, K.A.5
Zigler, A.J.6
-
22
-
-
0043169405
-
Effects of tyrosine kinase inhibitor STI571 on human mast cells bearing wild-type or mutated c-kit
-
Akin C, Brockow K, D'Ambrosio C, Kirshenbaum AS, Ma Y, Longley BJ, Metcalfe DD. Effects of tyrosine kinase inhibitor STI571 on human mast cells bearing wild-type or mutated c-kit. Exp Hematol 2003;31:686-92.
-
(2003)
Exp Hematol
, vol.31
, pp. 686-692
-
-
Akin, C.1
Brockow, K.2
D'Ambrosio, C.3
Kirshenbaum, A.S.4
Ma, Y.5
Longley, B.J.6
Metcalfe, D.D.7
-
23
-
-
0041656424
-
Imatinib for systemic mast-cell disease
-
Pardanani A, Elliott M, Reeder T, Li CY, Baxter EJ, Cross NC, Tefferi A. Imatinib for systemic mast-cell disease. Lancet 2003;362:535-6.
-
(2003)
Lancet
, vol.362
, pp. 535-536
-
-
Pardanani, A.1
Elliott, M.2
Reeder, T.3
Li, C.Y.4
Baxter, E.J.5
Cross, N.C.6
Tefferi, A.7
-
24
-
-
64249092051
-
Advanced mast cell disease: an Italian Hematological Multicenter experience
-
Pagano L, Valentini CG, Caira M, et al. Advanced mast cell disease: an Italian Hematological Multicenter experience. Int J Hematol 2008;88:483-8.
-
(2008)
Int J Hematol
, vol.88
, pp. 483-488
-
-
Pagano, L.1
Valentini, C.G.2
Caira, M.3
-
25
-
-
32844455834
-
A novel K509I mutation of KIT identified in familial mastocytosis-in vitro and in vivo responsiveness to imatinib therapy
-
Zhang LY, Smith ML, Schultheis B, Fitzgibbon J, Lister TA, Melo JV, Cross NC, Cavenagh JD. A novel K509I mutation of KIT identified in familial mastocytosis-in vitro and in vivo responsiveness to imatinib therapy. Leuk Res 2006;30:373-8.
-
(2006)
Leuk Res
, vol.30
, pp. 373-378
-
-
Zhang, L.Y.1
Smith, M.L.2
Schultheis, B.3
Fitzgibbon, J.4
Lister, T.A.5
Melo, J.V.6
Cross, N.C.7
Cavenagh, J.D.8
-
26
-
-
1842579440
-
A novel form of mastocytosis associated with a transmembrane c-kit mutation and response to imatinib
-
Akin C, Fumo G, Yavuz AS, Lipsky PE, Neckers L, Metcalfe DD. A novel form of mastocytosis associated with a transmembrane c-kit mutation and response to imatinib. Blood 2004;103:3222-5.
-
(2004)
Blood
, vol.103
, pp. 3222-3225
-
-
Akin, C.1
Fumo, G.2
Yavuz, A.S.3
Lipsky, P.E.4
Neckers, L.5
Metcalfe, D.D.6
-
27
-
-
84872814676
-
-
Novartis Pharmaceuticals Corporation. East Hanover, NJ: Novartis Pharmaceuticals Corporation.
-
Novartis Pharmaceuticals Corporation. Imatinib (Gleevec) Package Insert. East Hanover, NJ: Novartis Pharmaceuticals Corporation, 2012.
-
(2012)
Imatinib (Gleevec) Package Insert
-
-
-
28
-
-
0344987881
-
A tyrosine kinase created by fusion of the PDGFRA and FIP1L1 genes as a therapeutic target of imatinib in idiopathic hypereosinophilic syndrome
-
Cools J, DeAngelo DJ, Gotlib J, et al. A tyrosine kinase created by fusion of the PDGFRA and FIP1L1 genes as a therapeutic target of imatinib in idiopathic hypereosinophilic syndrome. N Engl J Med 2003;348:1201-14.
-
(2003)
N Engl J Med
, vol.348
, pp. 1201-1214
-
-
Cools, J.1
DeAngelo, D.J.2
Gotlib, J.3
-
29
-
-
10744228486
-
CHIC2 deletion, a surrogate for FIP1L1-PDGFRA fusion, occurs in systemic mastocytosis associated with eosinophilia and predicts response to imatinib mesylate therapy
-
Pardanani A, Ketterling RP, Brockman SR, et al. CHIC2 deletion, a surrogate for FIP1L1-PDGFRA fusion, occurs in systemic mastocytosis associated with eosinophilia and predicts response to imatinib mesylate therapy. Blood 2003;102:3093-6.
-
(2003)
Blood
, vol.102
, pp. 3093-3096
-
-
Pardanani, A.1
Ketterling, R.P.2
Brockman, S.R.3
-
30
-
-
84862252300
-
Complete response after imatinib mesylate therapy in a patient with well-differentiated systemic mastocytosis
-
Alvarez-Twose I, Gonzalez P, Morgado JM, Jara-Acevedo M, Sanchez-Munoz L, Matito A, Mollejo M, Orfao A, Escribano L. Complete response after imatinib mesylate therapy in a patient with well-differentiated systemic mastocytosis. J Clin Oncol 2012;30:e126-9.
-
(2012)
J Clin Oncol
, vol.30
-
-
Alvarez-Twose, I.1
Gonzalez, P.2
Morgado, J.M.3
Jara-Acevedo, M.4
Sanchez-Munoz, L.5
Matito, A.6
Mollejo, M.7
Orfao, A.8
Escribano, L.9
-
31
-
-
84872792020
-
-
Novartis Pharma AG. Stein, Switzerland: Novartis Pharma AG.
-
Novartis Pharma AG. Nilotinib (Tasigna) Package Insert. Stein, Switzerland: Novartis Pharma AG, 2012.
-
(2012)
Nilotinib (Tasigna) Package Insert
-
-
-
32
-
-
75349094716
-
Extended kinase profile and properties of the protein kinase inhibitor nilotinib
-
Manley PW, Drueckes P, Fendrich G, Furet P, Liebetanz J, Martiny-Baron G, Mestan J, Trappe J, Wartmann M, Fabbro D. Extended kinase profile and properties of the protein kinase inhibitor nilotinib. Biochim Biophys Acta 2010;1804:445-53.
-
(2010)
Biochim Biophys Acta
, vol.1804
, pp. 445-453
-
-
Manley, P.W.1
Drueckes, P.2
Fendrich, G.3
Furet, P.4
Liebetanz, J.5
Martiny-Baron, G.6
Mestan, J.7
Trappe, J.8
Wartmann, M.9
Fabbro, D.10
-
33
-
-
26944458584
-
The systemic mastocytosis-specific activating cKit mutation D816V can be inhibited by the tyrosine kinase inhibitor AMN107
-
von Bubnoff N, Gorantla SH, Kancha RK, Lordick F, Peschel C, Duyster J. The systemic mastocytosis-specific activating cKit mutation D816V can be inhibited by the tyrosine kinase inhibitor AMN107. Leukemia 2005;19:1670-1.
-
(2005)
Leukemia
, vol.19
, pp. 1670-1671
-
-
von Bubnoff, N.1
Gorantla, S.H.2
Kancha, R.K.3
Lordick, F.4
Peschel, C.5
Duyster, J.6
-
34
-
-
33748114504
-
Effects of AMN107, a novel aminopyrimidine tyrosine kinase inhibitor, on human mast cells bearing wild-type or mutated codon 816 c-kit
-
Verstovsek S, Akin C, Manshouri T, Quintas-Cardama A, Huynh L, Manley P, Tefferi A, Cortes J, Giles FJ, Kantarjian H. Effects of AMN107, a novel aminopyrimidine tyrosine kinase inhibitor, on human mast cells bearing wild-type or mutated codon 816 c-kit. Leuk Res 2006;30:1365-70.
-
(2006)
Leuk Res
, vol.30
, pp. 1365-1370
-
-
Verstovsek, S.1
Akin, C.2
Manshouri, T.3
Quintas-Cardama, A.4
Huynh, L.5
Manley, P.6
Tefferi, A.7
Cortes, J.8
Giles, F.J.9
Kantarjian, H.10
-
35
-
-
49449112613
-
A phase II study of nilotinib, a novel inhibitor of c-Kit, PDGFR, and Bcr-Abl, administered to patients with systemic mastocytosis
-
Abstract 2703.
-
Hochhaus A, Ottmann OG, Lauber S, Hughes T, Verhoef G, Schwarer AP, Gratwohl A, Rafferty T, Resta D, Gattermann N. A phase II study of nilotinib, a novel inhibitor of c-Kit, PDGFR, and Bcr-Abl, administered to patients with systemic mastocytosis. Blood 2006;108:Abstract 2703.
-
(2006)
Blood
, vol.108
-
-
Hochhaus, A.1
Ottmann, O.G.2
Lauber, S.3
Hughes, T.4
Verhoef, G.5
Schwarer, A.P.6
Gratwohl, A.7
Rafferty, T.8
Resta, D.9
Gattermann, N.10
-
36
-
-
77953691179
-
Nilotinib versus imatinib for newly diagnosed chronic myeloid leukemia
-
Saglio G, Kim DW, Issaragrisil S, et al. Nilotinib versus imatinib for newly diagnosed chronic myeloid leukemia. N Engl J Med 2010;362:2251-9.
-
(2010)
N Engl J Med
, vol.362
, pp. 2251-2259
-
-
Saglio, G.1
Kim, D.W.2
Issaragrisil, S.3
-
37
-
-
35748952533
-
Dasatinib: a new step in molecular target therapy
-
Olivieri A, Manzione L. Dasatinib: a new step in molecular target therapy. Ann Oncol 2007;18:vi42-6.
-
(2007)
Ann Oncol
, vol.18
-
-
Olivieri, A.1
Manzione, L.2
-
38
-
-
33645687784
-
Dasatinib (BMS-354825) inhibits KITD816V, an imatinib-resistant activating mutation that triggers neoplastic growth in most patients with systemic mastocytosis
-
Shah NP, Lee FY, Luo R, Jiang Y, Donker M, Akin C. Dasatinib (BMS-354825) inhibits KITD816V, an imatinib-resistant activating mutation that triggers neoplastic growth in most patients with systemic mastocytosis. Blood 2006;108:286-91.
-
(2006)
Blood
, vol.108
, pp. 286-291
-
-
Shah, N.P.1
Lee, F.Y.2
Luo, R.3
Jiang, Y.4
Donker, M.5
Akin, C.6
-
39
-
-
52449085884
-
Phase II study of dasatinib in Philadelphia chromosome-negative acute and chronic myeloid diseases, including systemic mastocytosis
-
Verstovsek S, Tefferi A, Cortes J, et al. Phase II study of dasatinib in Philadelphia chromosome-negative acute and chronic myeloid diseases, including systemic mastocytosis. Clin Cancer Res 2008;14:3906-15.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 3906-3915
-
-
Verstovsek, S.1
Tefferi, A.2
Cortes, J.3
-
40
-
-
77953725855
-
Dasatinib versus imatinib in newly diagnosed chronic-phase chronic myeloid leukemia
-
Kantarjian H, Shah NP, Hochhaus A, et al. Dasatinib versus imatinib in newly diagnosed chronic-phase chronic myeloid leukemia. N Engl J Med 2010;362:2260-70.
-
(2010)
N Engl J Med
, vol.362
, pp. 2260-2270
-
-
Kantarjian, H.1
Shah, N.P.2
Hochhaus, A.3
-
41
-
-
41849136506
-
Dasatinib therapy for systemic mastocytosis: four cases
-
Purtill D, Cooney J, Sinniah R, Carnley B, Cull G, Augustson B, Cannell P. Dasatinib therapy for systemic mastocytosis: four cases. Eur J Haematol 2008;80:456-8.
-
(2008)
Eur J Haematol
, vol.80
, pp. 456-458
-
-
Purtill, D.1
Cooney, J.2
Sinniah, R.3
Carnley, B.4
Cull, G.5
Augustson, B.6
Cannell, P.7
-
42
-
-
70349658639
-
Masitinib (AB1010), a potent and selective tyrosine kinase inhibitor targeting KIT
-
Dubreuil P, Letard S, Ciufolini M, et al. Masitinib (AB1010), a potent and selective tyrosine kinase inhibitor targeting KIT. PLoS ONE 2009;4:e7258.
-
(2009)
PLoS ONE
, vol.4
-
-
Dubreuil, P.1
Letard, S.2
Ciufolini, M.3
-
43
-
-
78649504351
-
Masitinib for the treatment of systemic and cutaneous mastocytosis with handicap: a phase 2a study
-
Paul C, Sans B, Suarez F, et al. Masitinib for the treatment of systemic and cutaneous mastocytosis with handicap: a phase 2a study. Am J Hematol 2010;85:921-5.
-
(2010)
Am J Hematol
, vol.85
, pp. 921-925
-
-
Paul, C.1
Sans, B.2
Suarez, F.3
-
44
-
-
84862578484
-
Mast cell leukemia: identification of a new c-Kit mutation, dup(501-502), and response to Masitinib, a c-Kit tyrosine kinase inhibitor
-
Georgin-Lavialle S, Lhermitte L, Suarez F, et al. Mast cell leukemia: identification of a new c-Kit mutation, dup(501-502), and response to Masitinib, a c-Kit tyrosine kinase inhibitor. Eur J Haematol 2012;89:47-52.
-
(2012)
Eur J Haematol
, vol.89
, pp. 47-52
-
-
Georgin-Lavialle, S.1
Lhermitte, L.2
Suarez, F.3
-
45
-
-
0036720398
-
The roles of FLT3 in hematopoiesis and leukemia
-
Gilliland DG, Griffin JD. The roles of FLT3 in hematopoiesis and leukemia. Blood 2002;100:1532-42.
-
(2002)
Blood
, vol.100
, pp. 1532-1542
-
-
Gilliland, D.G.1
Griffin, J.D.2
-
46
-
-
18844478996
-
PKC412-a protein kinase inhibitor with a broad therapeutic potential
-
Fabbro D, Ruetz S, Bodis S, Pruschy M, Csermak K, Man A, Campochiaro P, Wood J, O'Reilly T, Meyer T. PKC412-a protein kinase inhibitor with a broad therapeutic potential. Anticancer Drug Des 2000;15:17-28.
-
(2000)
Anticancer Drug Des
, vol.15
, pp. 17-28
-
-
Fabbro, D.1
Ruetz, S.2
Bodis, S.3
Pruschy, M.4
Csermak, K.5
Man, A.6
Campochiaro, P.7
Wood, J.8
O'Reilly, T.9
Meyer, T.10
-
47
-
-
79960404044
-
KIT inhibitor midostaurin exhibits a high rate of clinically meaningful and durable responses in advanced systemic mastocytosis: report of a fully accrued phase II trial
-
Abstract 316.
-
Gotlib J, DeAngelo DJ, George TI, Corless CL, Linder A, Langford C, Dutreix C, Gross S, Nikolova Z, Graubert T. KIT inhibitor midostaurin exhibits a high rate of clinically meaningful and durable responses in advanced systemic mastocytosis: report of a fully accrued phase II trial. Blood 2010;116:Abstract 316.
-
(2010)
Blood
, vol.116
-
-
Gotlib, J.1
DeAngelo, D.J.2
George, T.I.3
Corless, C.L.4
Linder, A.5
Langford, C.6
Dutreix, C.7
Gross, S.8
Nikolova, Z.9
Graubert, T.10
-
48
-
-
30444446680
-
PKC412 inhibits in vitro growth of neoplastic human mast cells expressing the D816V-mutated variant of KIT: comparison with AMN107, imatinib, and cladribine (2CdA) and evaluation of cooperative drug effects
-
Gleixner KV, Mayerhofer M, Aichberger KJ, et al. PKC412 inhibits in vitro growth of neoplastic human mast cells expressing the D816V-mutated variant of KIT: comparison with AMN107, imatinib, and cladribine (2CdA) and evaluation of cooperative drug effects. Blood 2006;107:752-9.
-
(2006)
Blood
, vol.107
, pp. 752-759
-
-
Gleixner, K.V.1
Mayerhofer, M.2
Aichberger, K.J.3
-
49
-
-
84872798845
-
Midostaurin a multi-targeted oral kinase inhibitor in systemic mastocytosis: report of an open-label compassionate use program in the United Kingdom
-
Abstract 5145.
-
Knapper S, Cullis J, Drummond MW, Evely R, Everington T, Hoyle C, McLintock L, Poynton C, Radia D. Midostaurin a multi-targeted oral kinase inhibitor in systemic mastocytosis: report of an open-label compassionate use program in the United Kingdom. Blood 2011;118:Abstract 5145.
-
(2011)
Blood
, vol.118
-
-
Knapper, S.1
Cullis, J.2
Drummond, M.W.3
Evely, R.4
Everington, T.5
Hoyle, C.6
McLintock, L.7
Poynton, C.8
Radia, D.9
-
50
-
-
84872800619
-
KIT inhibitor midostaurin in patients with advanced systemic mastocytosis: results of a planned interim analysis of the global CPKC412D2201 trial
-
Abstract 799.
-
Gotlib J, Kluin-Nelemans HC, George TI, et al. KIT inhibitor midostaurin in patients with advanced systemic mastocytosis: results of a planned interim analysis of the global CPKC412D2201 trial. Blood 2012;120:Abstract 799.
-
(2012)
Blood
, vol.120
-
-
Gotlib, J.1
Kluin-Nelemans, H.C.2
George, T.I.3
-
51
-
-
80051475544
-
Tyrosine kinase inhibitors in the treatment of systemic mastocytosis
-
Ustun C, DeRemer DL, Akin C. Tyrosine kinase inhibitors in the treatment of systemic mastocytosis. Leuk Res 2011;35:1143-52.
-
(2011)
Leuk Res
, vol.35
, pp. 1143-1152
-
-
Ustun, C.1
DeRemer, D.L.2
Akin, C.3
-
52
-
-
21344439293
-
Systemic mastocytosis: bone marrow pathology, classification, and current therapies
-
Pardanani A. Systemic mastocytosis: bone marrow pathology, classification, and current therapies. Acta Haematol 2005;114:41-51.
-
(2005)
Acta Haematol
, vol.114
, pp. 41-51
-
-
Pardanani, A.1
-
53
-
-
0036202125
-
Mastocytosis and fibrosis: role of cytokines
-
Li CY, Baek JY. Mastocytosis and fibrosis: role of cytokines. Int Arch Allergy Immunol 2002;127:123-6.
-
(2002)
Int Arch Allergy Immunol
, vol.127
, pp. 123-126
-
-
Li, C.Y.1
Baek, J.Y.2
-
54
-
-
79952336888
-
Clonal analysis of NRAS activating mutations in KIT-D816V systemic mastocytosis
-
Wilson TM, Maric I, Simakova O, Bai Y, Chan EC, Olivares N, Carter M, Maric D, Robyn J, Metcalfe DD. Clonal analysis of NRAS activating mutations in KIT-D816V systemic mastocytosis. Haematologica 2011;96:459-63.
-
(2011)
Haematologica
, vol.96
, pp. 459-463
-
-
Wilson, T.M.1
Maric, I.2
Simakova, O.3
Bai, Y.4
Chan, E.C.5
Olivares, N.6
Carter, M.7
Maric, D.8
Robyn, J.9
Metcalfe, D.D.10
-
55
-
-
84872827684
-
Ponatinib exerts growth-inhibitory effects on neoplastic mast cells and synergizes with midostaurin in producing growth arrest and apoptosis
-
Abstract 3497.
-
Gleixner KV, Blatt K, Peter B, Hadzijusufovic E, Valent P. Ponatinib exerts growth-inhibitory effects on neoplastic mast cells and synergizes with midostaurin in producing growth arrest and apoptosis. Blood 2011;118:Abstract 3497.
-
(2011)
Blood
, vol.118
-
-
Gleixner, K.V.1
Blatt, K.2
Peter, B.3
Hadzijusufovic, E.4
Valent, P.5
-
56
-
-
34250024319
-
REMA. Recent advances in the understanding of mastocytosis: the role of KIT mutations
-
Orfao A, Garcia-Montero AC, Sanchez L, Escribano L. REMA. Recent advances in the understanding of mastocytosis: the role of KIT mutations. Br J Haematol 2007;138:12-30.
-
(2007)
Br J Haematol
, vol.138
, pp. 12-30
-
-
Orfao, A.1
Garcia-Montero, A.C.2
Sanchez, L.3
Escribano, L.4
-
57
-
-
19444371824
-
A germline mutation in KIT in familial diffuse cutaneous mastocytosis
-
Tang X, Boxer M, Drummond A, Ogston P, Hodgins M, Burden AD. A germline mutation in KIT in familial diffuse cutaneous mastocytosis. J Med Genet 2004;41:e88.
-
(2004)
J Med Genet
, vol.41
-
-
Tang, X.1
Boxer, M.2
Drummond, A.3
Ogston, P.4
Hodgins, M.5
Burden, A.D.6
-
58
-
-
76649094569
-
Pediatric mastocytosis is a clonal disease associated with D816V and other activating c-KIT mutations
-
Bodemer C, Hermine O, Palmerini F, et al. Pediatric mastocytosis is a clonal disease associated with D816V and other activating c-KIT mutations. J Invest Dermatol 2010;130:804-15.
-
(2010)
J Invest Dermatol
, vol.130
, pp. 804-815
-
-
Bodemer, C.1
Hermine, O.2
Palmerini, F.3
-
59
-
-
13044305857
-
Activating and dominant inactivating c-KIT catalytic domain mutations in distinct clinical forms of human mastocytosis
-
Longley BJ Jr, Metcalfe DD, Tharp M, Wang X, Tyrrell L, Lu SZ, Heitjan D, Ma Y. Activating and dominant inactivating c-KIT catalytic domain mutations in distinct clinical forms of human mastocytosis. Proc Natl Acad Sci USA 1999;96:1609-14.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 1609-1614
-
-
Longley Jr, B.J.1
Metcalfe, D.D.2
Tharp, M.3
Wang, X.4
Tyrrell, L.5
Lu, S.Z.6
Heitjan, D.7
Ma, Y.8
-
60
-
-
0037405219
-
Systemic mastocytosis with associated clonal hematological non-mast-cell lineage disease: analysis of clinicopathologic features and activating c-kit mutations
-
Pullarkat VA, Bueso-Ramos C, Lai R, Kroft S, Wilson CS, Pullarkat ST, Bu X, Thein M, Lee M, Brynes RK. Systemic mastocytosis with associated clonal hematological non-mast-cell lineage disease: analysis of clinicopathologic features and activating c-kit mutations. Am J Hematol 2003;73:12-7.
-
(2003)
Am J Hematol
, vol.73
, pp. 12-17
-
-
Pullarkat, V.A.1
Bueso-Ramos, C.2
Lai, R.3
Kroft, S.4
Wilson, C.S.5
Pullarkat, S.T.6
Bu, X.7
Thein, M.8
Lee, M.9
Brynes, R.K.10
-
61
-
-
0009013631
-
Somatic c-KIT activating mutation in urticaria pigmentosa and aggressive mastocytosis: establishment of clonality in a human mast cell neoplasm
-
Longley BJ, Tyrrell L, Lu SZ, Ma YS, Langley K, Ding TG, Duffy T, Jacobs P, Tang LH, Modlin I. Somatic c-KIT activating mutation in urticaria pigmentosa and aggressive mastocytosis: establishment of clonality in a human mast cell neoplasm. Nat Genet 1996;12:312-4.
-
(1996)
Nat Genet
, vol.12
, pp. 312-314
-
-
Longley, B.J.1
Tyrrell, L.2
Lu, S.Z.3
Ma, Y.S.4
Langley, K.5
Ding, T.G.6
Duffy, T.7
Jacobs, P.8
Tang, L.H.9
Modlin, I.10
-
62
-
-
0031039992
-
A new c-kit mutation in a case of aggressive mast cell disease
-
Pignon JM, Giraudier S, Duquesnoy P, Jouault H, Imbert M, Vainchenker W, Vernant JP, Tulliez M. A new c-kit mutation in a case of aggressive mast cell disease. Br J Haematol 1997;96:374-6.
-
(1997)
Br J Haematol
, vol.96
, pp. 374-376
-
-
Pignon, J.M.1
Giraudier, S.2
Duquesnoy, P.3
Jouault, H.4
Imbert, M.5
Vainchenker, W.6
Vernant, J.P.7
Tulliez, M.8
-
63
-
-
79960629726
-
Novel, activating KIT-N822I mutation in familial cutaneous mastocytosis
-
Wasag B, Niedoszytko M, Piskorz A, Lange M, Renke J, Jassem E, Biernat W, Debiec-Rychter M, Limon J. Novel, activating KIT-N822I mutation in familial cutaneous mastocytosis. Exp Hematol 2011;39:859-65.e2.
-
(2011)
Exp Hematol
, vol.39
-
-
Wasag, B.1
Niedoszytko, M.2
Piskorz, A.3
Lange, M.4
Renke, J.5
Jassem, E.6
Biernat, W.7
Debiec-Rychter, M.8
Limon, J.9
-
64
-
-
0344643427
-
One-step detection of c-kit point mutations using peptide nucleic acid-mediated polymerase chain reaction clamping and hybridization probes
-
Sotlar K, Escribano L, Landt O, Mohrle S, Herrero S, Torrelo A, Lass U, Horny HP, Bultmann B. One-step detection of c-kit point mutations using peptide nucleic acid-mediated polymerase chain reaction clamping and hybridization probes. Am J Pathol 2003;162:737-46.
-
(2003)
Am J Pathol
, vol.162
, pp. 737-746
-
-
Sotlar, K.1
Escribano, L.2
Landt, O.3
Mohrle, S.4
Herrero, S.5
Torrelo, A.6
Lass, U.7
Horny, H.P.8
Bultmann, B.9
-
65
-
-
0027359443
-
Identification of mutations in the coding sequence of the proto-oncogene c-kit in a human mast cell leukemia cell line causing ligand-independent activation of c-kit product
-
Furitsu T, Tsujimura T, Tono T, Ikeda H, Kitayama H, Koshimizu U, Sugahara H, Butterfield JH, Ashman LK, Kanayama Y. Identification of mutations in the coding sequence of the proto-oncogene c-kit in a human mast cell leukemia cell line causing ligand-independent activation of c-kit product. J Clin Invest 1993;92:1736-44.
-
(1993)
J Clin Invest
, vol.92
, pp. 1736-1744
-
-
Furitsu, T.1
Tsujimura, T.2
Tono, T.3
Ikeda, H.4
Kitayama, H.5
Koshimizu, U.6
Sugahara, H.7
Butterfield, J.H.8
Ashman, L.K.9
Kanayama, Y.10
-
66
-
-
33947520803
-
Juxtamembrane-type c-kit gene mutation found in aggressive systemic mastocytosis induces imatinib-resistant constitutive KIT activation
-
Nakagomi N, Hirota S. Juxtamembrane-type c-kit gene mutation found in aggressive systemic mastocytosis induces imatinib-resistant constitutive KIT activation. Lab Invest 2007;87:365-71.
-
(2007)
Lab Invest
, vol.87
, pp. 365-371
-
-
Nakagomi, N.1
Hirota, S.2
-
67
-
-
84863723014
-
A global, phase II, single-arm, open-label study to determine the efficacy of midostaurin in patients with aggressive systemic mastocytosis (ASM) or mast cell leukemia (MCL) with or without an associated hematologic clonal nonmast cell lineage disease (AHNMD)
-
Abstract TPS200.
-
Gotlib J, Kluin-Nelemans H, Mauro M, et al. A global, phase II, single-arm, open-label study to determine the efficacy of midostaurin in patients with aggressive systemic mastocytosis (ASM) or mast cell leukemia (MCL) with or without an associated hematologic clonal nonmast cell lineage disease (AHNMD). J Clin Oncol 2011;29:Abstract TPS200.
-
(2011)
J Clin Oncol
, vol.29
-
-
Gotlib, J.1
Kluin-Nelemans, H.2
Mauro, M.3
-
68
-
-
76749089140
-
Systemic mastocytosis in adults: a review on prognosis and treatment based on 342 Mayo Clinic patients and current literature
-
Pardanani A, Tefferi A. Systemic mastocytosis in adults: a review on prognosis and treatment based on 342 Mayo Clinic patients and current literature. Curr Opin Hematol 2010;17:125-32.
-
(2010)
Curr Opin Hematol
, vol.17
, pp. 125-132
-
-
Pardanani, A.1
Tefferi, A.2
|