A new class of NO-donor pro-drugs triggered by γ-glutamyl transpeptidase with potential for reno-selective vasodilatation

Chemical Communications

Volumn 49, Issue 14, 2013, Pages 1389-1391

  Qingzhi, Zhang ^a   Agnieszka, Kulczynska ^a   Webb, David J ^b   Megson, Ian L ^c   Botting, Nigel P ^a  

^a UNIVERSITY OF ST ANDREWS   (United Kingdom)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

^c UNIVERSITY OF THE HIGHLANDS AND ISLANDS   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA GLUTAMYLTRANSFERASE; GUANIDINE DERIVATIVE; N GAMMA GLUTAMYLAMINOBENZYLOXY GUANIDINE; N HYDROXYGUANIDINE; NITRIC OXIDE; PRODRUG; UNCLASSIFIED DRUG;

ACUTE KIDNEY FAILURE; ARTICLE; CYCLIZATION; DRUG SYNTHESIS; ENZYME ACTIVATION; IN VITRO STUDY; KIDNEY INJURY; VASODILATATION;

EID: 84872738180     PISSN: 13597345     EISSN: 1364548X     Source Type: Journal    
DOI: 10.1039/c2cc38382a     Document Type: Article

References (26)

1. R. W. Schrier, W. Wang, B. Poole, A. Mitra, J. Clin. Invest., 2004, 114:5-14
2. J. V. Bonvebtre, J. M. Weinberg, J. Am. Soc. Nephrol., 2003, 14:2199-2210
3. T. A. Sutton, C. J. Fisher, B. A. Molitoris, Kidney Int., 2002, 62:1539-1549
4. G. Mariscalco, R. Lorusso, C. Dominici, A. Renzulli, A. Sala, Ann. Thorac. Surg., 2011, 92:1539-1547
5. P. A. Grace, Br. J. Surg., 1994, 81:637-647
6. M. L. Brocq, S. J. Leslie, P. Milliken, I. L. Megson, Antioxid. Redox Signaling, 2008, 10:1631-1674
7. A. MacKenzie, W. Martin, Br. J. Pharmacol., 1998, 124:710-728
8. M. Saran, C. Michel, W. Bors, Free Radical Res. Commun., 1990, 10:221-226
9. M. D. Denton, G. M. Chertow, H. R. Brady, Kidney Int., 1996, 49:4-14
10. T. Bove, G. Landoni, M. G. Calabró, G. Aletti, G. Marino, E. Cerchierini, G. Crescenzi, A. Zangrillo, Circulation, 2005, 111:3230-3235
11. P. G. Wang, T. B. Cai, and N. Taniguchi, Nitric Oxide Donors: For Pharmaceutical and Biological Applications, Wiley-VCH, 2005, ISBN, 3-527-31015-0
12. A. Renodon-Cornière, S. Dijols, C. Perollier, D. Lefevre-Groboillot, J. L. Boucher, R. Attias, M. A. Sari, D. Stuehr, D. Mansuy, J. Med. Chem., 2002, 45:944-954
13. D. Mansuy, J. L. Boucher, Drug Metab. Rev., 2002, 34:593-606
14. M. Xian, X. P. Li, X. P. Tang, X. C. Chen, X. L. Zheng, J. J. Galligan, D. L. Kreulen, P. G. Wang, Bioorg. Med. Chem. Lett., 2001, 11:2377-2380
15. M. Xian, N. Fujiwara, T. Cai, Z. Wen, S. Kazuma, A. Janczuk, X. Tang, V. Telyatnikov, Y. Miyamoto, N. Taniguchi, P. G. Wang, Bioorg. Med. Chem., 2002, 10:3049-3055
16. Q. Jia, T. Cai, M. Huang, H. Li, M. Xian, T. L. Poulos, P. G. Wang, J. Med. Chem., 2003, 46:2271-2274
17. D. Schade, J. Kotthaus, H. Hungeling, J. Kotthaus, B. Clement, ChemMedChem, 2009, 4:1595-1599
18. D. Schade, J. Kotthaus, N. Klein, J. Kotthaus, B. Clement, Org. Biomol. Chem., 2011, 9:5249-5259
19. J. P. Ward, Ann. R. Coll. Surg. Engl., 1975, 57:248-261
20. S. Wilk, H. Mizoguchi, M. Orlowski, J. Pharmacol. Exp. Ther., 1978, 206:227-232
21. M. Barthelmebs, A. Caillette, J. D. Ehrhardt, J. Velly, J. L. Imbs, Kidney Int., 1990, 37:1414-1422
22. R. G. G. Leenders, K. A. A. Gerrits, R. Ruijtenbeek, H. W. Scheeren, Tetrahedron Lett., 1995, 36:1701-1704
23. A. Ménard, R. Castonguay, C. Lherbet, C. Rivard, Y. Roupioz, J. W. Keillor, Biochemistry, 2001, 40:12678-12685
24. B. E. Toki, C. G. Cerveny, A. F. Wahl, P. D. Senter, J. Org. Chem., 2002, 67:1866-1872
25. M. Sato, T. Ishii, Y. Kobayashi-Matsunaga, H. Amada, K. Taniguchi, N. Miyata, K. Kameo, Bioorg. Med. Chem. Lett., 2001, 11:2993-2995
26. N. Miyata, T. Seki, Y. Tanaka, T. Omura, K. Taniguchi, M. Doi, K. Bandou, S. Kametani, M. Sato, S. Okuyama, L. Cambj-Sapunar, D. R. Harder, R. J. Roman, J. Pharmacol. Exp. Ther., 2005, 314:77-85