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Volumn 11, Issue 23, 2001, Pages 2993-2995
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Discovery of a N′-hydroxyphenylformamidine derivative HET0016 as a potent and selective 20-HETE synthase inhibitor
a
a
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Author keywords
[No Author keywords available]
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Indexed keywords
20 HYDROXY 5,8,11,14 EICOSATETRAENOIC ACID SYNTHASE;
ARACHIDONIC ACID;
CYTOCHROME P450;
ENZYME INHIBITOR;
FORMAMIDINE;
HYDROXYFORMAMIDINE DERIVATIVE;
KIDNEY ENZYME;
N (4 BUTYL 2 METHYLPHENYL) N' HYDROXYFORMAMIDINE;
N HYDROXYFORMAMIDINE;
UNCLASSIFIED DRUG;
20 HYDROXY 5,8,11,14 EICOSATETRAENOIC ACID;
20-HYDROXY-5,8,11,14-EICOSATETRAENOIC ACID;
AMIDINE;
CYTOCHROME P450 2D6;
HYDROXYICOSATETRAENOIC ACID;
N HYDROXY N' (4 BUTYL 2 METHYLPHENYL)FORMAMIDINE;
N-HYDROXY-N'-(4-BUTYL-2-METHYLPHENYL)FORMAMIDINE;
ARTICLE;
CONTROLLED STUDY;
DERIVATIZATION;
DRUG ACTIVITY;
DRUG POTENCY;
DRUG SCREENING;
DRUG SELECTIVITY;
DRUG STRUCTURE;
HUMAN;
HUMAN CELL;
IC 50;
KIDNEY MICROSOME;
REACTION ANALYSIS;
STRUCTURE ACTIVITY RELATION;
CHEMISTRY;
DRUG ANTAGONISM;
DRUG EFFECT;
KIDNEY;
METABOLISM;
MICROSOME;
AMIDINES;
CYTOCHROME P-450 CYP2D6;
DRUG EVALUATION, PRECLINICAL;
ENZYME INHIBITORS;
HUMANS;
HYDROXYEICOSATETRAENOIC ACIDS;
INHIBITORY CONCENTRATION 50;
KIDNEY;
MICROSOMES;
STRUCTURE-ACTIVITY RELATIONSHIP;
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EID: 0035802851
PISSN: 0960894X
EISSN: None
Source Type: Journal
DOI: 10.1016/S0960-894X(01)00614-X Document Type: Article |
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Times cited : (36)
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References (13)
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