The four and a half lim-only protein 2 (FHL2) activates transforming growth factor β (TGF-β) Signaling by regulating ubiquitination of the E3 ligase arkadia

Journal of Biological Chemistry

Volumn 288, Issue 3, 2013, Pages 1785-1794

  Xia, Tian ^a,b   Lévy, Laurence ^c   Levillayer, Florence ^b   Jia, Baosen ^a   Li, Gaiyun ^a   Neuveut, Christine ^b   Buendia, Marie Annick ^b,c   Lan, Ke ^a   Wei, Yu ^b  

^a INSTITUTE PASTEUR OF SHANGHAI   (China)

^b INSTITUT PASTEUR   (France)

^c INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOCATALYTIC PROCESS; C-TERMINAL REGIONS; E3 LIGASE; GENE RESPONSE; MOLECULAR BASIS; POLYUBIQUITINATION; REGULATORY MECHANISM; RNA INTERFERENCE; SINGLE MUTATION; TRANSFORMING GROWTH FACTORS; UBIQUITIN; UBIQUITIN LIGASES; UBIQUITINATION;

AMINO ACIDS; PROTEINS; RNA; SIGNAL TRANSDUCTION; TRANSCRIPTION;

SIGNALING;

ARKADIA PROTEIN; FOUR AND A HALF LIM ONLY PROTEIN 2; LYSINE; NUCLEIC ACID BINDING PROTEIN; SMAD3 PROTEIN; SMAD4 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; EMBRYO; GENE MUTATION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PROTEIN INTERACTION; RING FINGER MOTIF; SIGNAL TRANSDUCTION; UBIQUITINATION;

ANIMALS; BINDING SITES; CELL LINE, TUMOR; FIBROBLASTS; GENE EXPRESSION REGULATION; GENES, REPORTER; HALF-LIFE; HUMANS; LIM-HOMEODOMAIN PROTEINS; LUCIFERASES; MICE; MUSCLE PROTEINS; MUTATION; NUCLEAR PROTEINS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; TRANSFECTION; TRANSFORMING GROWTH FACTOR BETA; UBIQUITIN; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION;

EID: 84872735710     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.439760     Document Type: Article

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