Studies of (±)-3,4-methylenedioxymethamphetamine (mdma) metabolism and disposition in rats and mice: Relationship to neuroprotection and neurotoxicity profile

Journal of Pharmacology and Experimental Therapeutics

Volumn 344, Issue 2, 2013, Pages 479-488

  Mueller, Melanie ^a   Maldonado Adrian, Concepcion ^a   Yuan, Jie ^a   McCann, Una D ^a   Ricaurte, George A ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3,4 DIHYDROXYPHENYLACETIC ACID; 3,4 METHYLENEDIOXYMETHAMPHETAMINE; 5 HYDROXYINDOLEACETIC ACID; BIOLOGICAL MARKER; DOPAMINE; SEROTONIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD LEVEL; BODY TEMPERATURE; BRAIN METABOLISM; CHEMICAL ANALYSIS; CONTROLLED STUDY; DOPAMINERGIC SYSTEM; INDUCED HYPOTHERMIA; MALE; METABOLITE; NEUROCHEMISTRY; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT; SEROTONINERGIC SYSTEM; TEMPERATURE SENSITIVITY; THERAPY EFFECT; TREATMENT OUTCOME;

ADMINISTRATION, ORAL; ANIMALS; BIOTRANSFORMATION; BODY TEMPERATURE; BRAIN; DOPAMINE; DOSE-RESPONSE RELATIONSHIP, DRUG; HYPOTHERMIA, INDUCED; MALE; MICE; MICE, INBRED STRAINS; N-METHYL-3,4-METHYLENEDIOXYAMPHETAMINE; NEURONS; NEUROTOXICITY SYNDROMES; RATS; RATS, SPRAGUE-DAWLEY; SEROTONIN; SPECIES SPECIFICITY; TIME FACTORS; TISSUE DISTRIBUTION;

EID: 84872698893     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.112.201699     Document Type: Article

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