Cytotoxic and apoptosis-inducing activities of 12-O-acetylazedarachin B from the fruits of Melia azedarach in human cancer cell lines

Biological and Pharmaceutical Bulletin

Volumn 36, Issue 1, 2013, Pages 135-139

  Kikuchi, Takashi ^a,b   Pan, Xin ^a   Ishii, Koichi ^a   Nakamura, Yasuhiro ^a   Ogihara, Eri ^a   Koike, Kazuo ^c   Tanaka, Reiko ^b   Akihisa, Toshihiro ^a  

^a NIHON UNIVERSITY   (Japan)

^b OSAKA MEDICAL COLLEGE   (Japan)

^c TOHO UNIVERSITY   (Japan)

Author keywords

12 O acetylazedarachin B; Apoptosis; Cytotoxic activity; Limonoid; Melia azedarach

Indexed keywords

12 O ACETYLAZEDARACHIN B; CASPASE 3; CASPASE 8; CASPASE 9; CISPLATIN; DEATH RECEPTOR; FLUOROURACIL; LIMONOID; MELIA AZEDARACH EXTRACT; PHOSPHOLIPID; PROCASPASE 3; PROCASPASE 8; PROCASPASE 9; PROTEIN BAX; PROTEIN BCL 2; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; DNA FRAGMENTATION; DRUG CYTOTOXICITY; DRUG IDENTIFICATION; DRUG ISOLATION; DRUG POTENCY; FRUIT; HUMAN; HUMAN CELL; IC 50; LEUKEMIA; MITOCHONDRION; STOMACH CANCER;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL CYCLE; CELL LINE, TUMOR; CELL SURVIVAL; FRUIT; HUMANS; LIMONINS; MELIA AZEDARACH; PLANT EXTRACTS;

EID: 84872691417     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.b12-00795     Document Type: Article

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