Metabolic therapy at the edge between human hosts and gut microbes;La thérapie métabolique à l'interface entre l'homme et le microbiote intestinal

Annales Pharmaceutiques Francaises

Volumn 71, Issue 1, 2013, Pages 34-41

  Blasco Baque, V ^a,b   Serino, M ^a   Burcelin, R ^a  

^a University Hospital of Toulouse   (France)

^b UNIVERSITÉ DE TOULOUSE   (France)

Author keywords

Gut microbiota; High fat diet; Metabolic disease; Personalized medicine; Pre probiotics

Indexed keywords

PREBIOTIC AGENT; PROBIOTIC AGENT;

ARTICLE; DIETARY FIBER; HOST; INTESTINE FLORA; METABOLIC DISORDER; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PERSONALIZED MEDICINE;

ANIMALS; GASTROINTESTINAL TRACT; HUMANS; INDIVIDUALIZED MEDICINE; INFLAMMATION; METABOLIC DISEASES; MICE;

EID: 84872684378     PISSN: 00034509     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pharma.2012.08.003     Document Type: Article

References (55)

1. Franks P.W., Hanson R.L., Knowler W.C., Sievers M.L., Bennett P.H., et al. Childhood obesity, other cardiovascular risk factors, and premature death. N Engl J Med 2010, 362:485-493.
2. Blasco-Baque V., Kemoun P., Loubieres P., Roumieux M., Heymes C., et al. Impact of periodontal disease on arterial pressure in diabetic mice. Ann Cardiol Angeiol (Paris) 2012, 61(3):173-177.
3. Blasco-Baque V Impact of type 2 diabetes on the development of periodontal disease in the mouse. Bull Group Int Rech Sci Stomatol Odontol 2011, 50(2):11-12.
4. Carulli L., Rondinella S., Lombardini S., Canedi I., Loria P., et al. Review article: diabetes, genetics and ethnicity. Aliment Pharmacol Ther 2005, 22(Suppl. 2):16-19.
5. Qin J., Li R., Raes J., Arumugam M., Burgdorf K.S., et al. A human gut microbial gene catalogue established by metagenomic sequencing. Nature 2010, 464:59-65.
6. Arumugam M., Raes J., Pelletier E., Le Paslier D., Yamada T., et al. Enterotypes of the human gut microbiome. Nature 2011, 473:174-180.
7. Ley R.E., Backhed F., Turnbaugh P., Lozupone C.A., Knight R.D., et al. Obesity alters gut microbial ecology. Proc Natl Acad Sci U S A 2005, 102:11070-11075.
8. Serino M., Luche E., Gres S., Baylac A., Berge M., et al. Metabolic adaptation to a high-fat diet is associated with a change in the gut microbiota. Gut 2012, 61:543-553.
9. Turnbaugh P.J., Hamady M., Yatsunenko T., Cantarel B.L., Duncan A., et al. A core gut microbiome in obese and lean twins. Nature 2009, 457:480-484.
10. Karlsson C.L., Onnerfalt J., Xu J., Molin G., Ahrne S., et al. The microbiota of the gut in preschool children with normal and excessive body weight. Obesity (Silver Spring) 2012, 10.1038/oby.2012.110.
11. Claesson M.J., Cusack S., O'Sullivan O., Greene-Diniz R., de Weerd H., et al. Composition, variability, and temporal stability of the intestinal microbiota of the elderly. Proc Natl Acad Sci U S A 2011, 108(Suppl. 1):4586-4591.
12. Turnbaugh P.J., Ley R.E., Mahowald M.A., Magrini V., Mardis E.R., et al. An obesity-associated gut microbiome with increased capacity for energy harvest. Nature 2006, 444:1027-1031.
13. Turnbaugh P., Ridaura V., Faith J., Rey F., Knight R., et al. The effect of diet on the human gut microbiome: a metagenomic analysis in humanized gnotobiotic mice. Sci Transl Med 2009, 1:6-14.
14. Backhed F., Ding H., Wang T., Hooper L.V., Koh G.Y., et al. The gut microbiota as an environmental factor that regulates fat storage. Proc Natl Acad Sci U S A 2004, 101:15718-15723.
15. Backhed F., Manchester J.K., Semenkovich C.F., Gordon J.I. Mechanisms underlying the resistance to diet-induced obesity in germ-free mice. Proc Natl Acad Sci U S A 2007, 104:979-984.
16. Shoelson S.E., Lee J., Goldfine A.B. Inflammation and insulin resistance. J Clin Invest 2006, 116:1793-1801.
17. Hotamisligil G.S. Inflammation and metabolic disorders. Nature 2006, 444:860-867.
18. Weisberg S.P., Hunter D., Huber R., Lemieux J., Slaymaker S., et al. CCR2 modulates inflammatory and metabolic effects of high-fat feeding. J Clin Invest 2006, 116:115-124.
19. Weisberg S.P., McCann D., Desai M., Rosenbaum M., Leibel R.L., et al. Obesity is associated with macrophage accumulation in adipose tissue. J Clin Invest 2003, 112:1796-1808.
20. Bouloumie A., Casteilla L., Lafontan M Adipose tissue lymphocytes and macrophages in obesity and insulin resistance: makers or markers, and which comes first ?. Arterioscler Thromb Vasc Biol 2008, 28:1211-1213.
21. Feuerer M., Herrero L., Cipolletta D., Naaz A., Wong J., et al. Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters. Nat Med 2009, 15:930-939.
22. Palmer C., Bik E.M., Digiulio D.B., Relman D.A., Brown PO Development of the human infant intestinal microbiota. PLoS Biol 2007, 5:e177.
23. Zoetendal E.G., Akkermans A.D., De Vos WM Temperature gradient gel electrophoresis analysis of 16S rRNA from human fecal samples reveals stable and host-specific communities of active bacteria. Appl Environ Microbiol 1998, 64:3854-3859.
24. Penders J., Thijs C., Vink C., Stelma F.F., Snijders B., et al. Factors influencing the composition of the intestinal microbiota in early infancy. Pediatrics 2006, 118:511-521.
25. Gronlund M.M., Lehtonen O.P., Eerola E., Kero P. Fecal microflora in healthy infants born by different methods of delivery: permanent changes in intestinal flora after cesarean delivery. J Pediatr Gastroenterol Nutr 1999, 28:19-25.
26. Orrhage K., Nord C.E. Factors controlling the bacterial colonization of the intestine in breastfed infants. Acta Paediatr Suppl 1999, 88:47-57.
27. Stappenbeck T.S., Hooper L.V., Gordon J.I. Developmental regulation of intestinal angiogenesis by indigenous microbes via Paneth cells. Proc Natl Acad Sci U S A 2002, 99:15451-15455.
28. Reinhardt C., Bergentall M., Greiner T.U., Schaffner F., Ostergren-Lunden G., et al. Tissue factor and PAR1 promote microbiota-induced intestinal vascular remodelling. Nature 2012, 483:627-631.
29. Hansen C.H., Nielsen D.S., Kverka M., Zakostelska Z., Klimesova K., et al. Patterns of early gut colonization shape future immune responses of the host. PLoS One 2012, 7:e34043.
30. Canani R.B., Costanzo M.D., Leone L., Bedogni G., Brambilla P., et al. Epigenetic mechanisms elicited by nutrition in early life. Nutr Res Rev 2011, 24:198-205.
31. Delzenne N.M., Neyrinck A.M., Cani P.D. Modulation of the gut microbiota by nutrients with prebiotic properties: consequences for host health in the context of obesity and metabolic syndrome. Microb Cell Fact 2011, 10(Suppl. 1):S10.
32. Amar J., Chabo C., Waget A., Klopp P., Vachoux C., et al. Intestinal mucosal adherence and translocation of commensal bacteria at the early onset of type 2 diabetes: molecular mechanisms and probiotic treatment. EMBO Mol Med 2011, 3:559-572.
33. Cani P.D., Knauf C., Iglesias M.A., Drucker D.J., Delzenne N.M., et al. Improvement of glucose tolerance and hepatic insulin sensitivity by oligofructose requires a functional glucagon-like peptide 1 receptor. Diabetes 2006, 55:1484-1490.
34. Cani P.D., Neyrinck A.M., Fava F., Knauf C., Burcelin R.G., et al. Selective increases of bifidobacteria in gut microflora improve high-fat diet-induced diabetes in mice through a mechanism associated with endotoxaemia. Diabetologia 2007, 50:2374-2383.
35. Khan M., Raoult D., Richet H., Lepidi H., La Scola B. Growth-promoting effects of single-dose intragastrically administered probiotics in chickens. Br Poult Sci 2007, 48:732-735.
36. Angelakis E., Bastelica D., Ben Amara A., El Filali A., Dutour A., et al. An evaluation of the effects of Lactobacillus ingluviei on body weight, the intestinal microbiome and metabolism in mice. Microb Pathog 2012, 52:61-68.
37. Amar J., Burcelin R., Ruidavets J.B., Cani P.D., Fauvel J., et al. Energy intake is associated with endotoxemia in apparently healthy men. Am J Clin Nutr 2008, 87:1219-1223.
38. Cani P.D., Amar J., Iglesias M.A., Poggi M., Knauf C., et al. Metabolic endotoxemia initiates obesity and insulin resistance. Diabetes 2007, 56:1761-1772.
39. Cani P.D., Bibiloni R., Knauf C., Waget A., Neyrinck A.M., et al. Changes in gut microbiota control metabolic endotoxemia-induced inflammation in high-fat diet-induced obesity and diabetes in mice. Diabetes 2008, 57:1470-1481.
40. Caesar R., Reigstad C.S., Backhed H.K., Reinhardt C., Ketonen M., et al. Gut-derived lipopolysaccharide augments adipose macrophage accumulation but is not essential for impaired glucose or insulin tolerance in mice. Gut 2012, 10.1136/gutjnl-2011-301689.
41. Velagapudi V.R., Hezaveh R., Reigstad C.S., Gopalacharyulu P., Yetukuri L., et al. The gut microbiota modulates host energy and lipid metabolism in mice. J Lipid Res 2010, 51:1101-1112.
42. Ueki K., Kondo T., Tseng Y.H., Kahn C.R. Central role of suppressors of cytokine signaling proteins in hepatic steatosis, insulin resistance, and the metabolic syndrome in the mouse. Proc Natl Acad Sci U S A 2004, 101:10422-10427.
43. Henao-Mejia J., Elinav E., Jin C., Hao L., Mehal W.Z., et al. Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity. Nature 2012.
44. Neish A.S. Microbes in gastro-intestinal health and disease. Gastroenterology 2009, 136:65-80.
45. Sansonetti P., Di Santo J. Debugging how bacteria manipulate the immune response. Immunity 2007, 26:149-161.
46. Carneiro L.A., Magalhaes J.G., Tattoli I., Philpott D.J., Travassos L.H. Nod-like proteins in inflammation and disease. J Pathol 2008, 214:136-148.
47. Hosoi T., Yokoyama S., Matsuo S., Akira S., Ozawa K. Myeloid differentiation factor 88 (MyD88)-deficiency increases risk of diabetes in mice. PLoS One 2010, 5(9). pii: e12537.
48. Poggi M., Bastelica D., Gual P., Iglesias M.A., Gremeaux T., et al. C3H/HeJ mice carrying a toll-like receptor 4 mutation are protected against the development of insulin resistance in white adipose tissue in response to a high-fat diet. Diabetologia 2007, 50:1267-1276.
49. Schertzer J.D., Tamrakar A.K., Magalhaes J.G., Pereira S., Bilan P.J., et al. NOD1 activators link innate immunity to insulin resistance. Diabetes 2011, 60:2206-2215.
50. Vijay-Kumar M., Aitken J.D., Carvalho F.A., Cullender T.C., Mwangi S., et al. Metabolic syndrome and altered gut microbiota in mice lacking Toll-like receptor 5. Science 2010, 328:228-231.
51. Vijay-Kumar M., Carvalho F.A., Aitken J.D., Fifadara N.H., Gewirtz A.T. TLR5 or NLRC4 is necessary and sufficient for promotion of humoral immunity by flagellin. Eur J Immunol 2010, 40:3528-3534.
52. Muccioli G.G., Naslain D., Backhed F., Reigstad C.S., Lambert D.M., et al. The endocannabinoid system links gut microbiota to adipogenesis. Mol Syst Biol 2010, 6:392.
53. Medici F., Hawa M., Ianari A., Pyke D.A., Leslie R.D. Concordance rate for type II diabetes mellitus in monozygotic twins: actuarial analysis. Diabetologia 1999, 42:146-150.
54. Burcelin R., Crivelli V., Dacosta A., Roy-Tirelli A., Thorens B Heterogeneous metabolic adaptation of C57BL/6J mice to high-fat diet. Am J Physiol Endocrinol Metab 2002, 282:E834-E842.
55. de Fourmestraux V., Neubauer H., Poussin C., Farmer P., Falquet L., et al. Transcript profiling suggests that differential metabolic adaptation of mice to a high-fat diet is associated with changes in liver to muscle lipid fluxes. J Biol Chem 2004, 279:50743-50753.